• Nutrition Research and Practice
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• v.3 no.2
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• pp.84-88
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• 2009

In our previous study, we have shown that berberine has both anti-adipogenic and anti-inflammatory effects on 3T3-L1 adipocytes, and the anti-adipogenic effect is due to the down-regulation of adipogenic enzymes and transcription factors. Here we focused more on anti-inflammatory effect of berberine using real time RT-PCR and found it changes expressions of adipokines. We hypothesized that anti-adipogenicity of berberine mediates anti-inflammtory effect and explored leptin as a candidate mediator of this signaling. We studied this hypothesis by western blot analysis, but our results showed that berberine has no effect on the phosphorylations of STAT-3 and ERK which have important roles on leptin signaling. These results led us to conclude that the anti-inflammatory effect of berberine is not mediated by the inhibition of leptin signal transduction. Moreover, we have found that berberine down-regulates NF-${\kappa}B$ signaling, one of the inflammation-related signaling pathway, through western blot analysis. Taken together, the anti-inflammatory effect of berberine is not mediated by leptin, and berberine induces anti-inflammatory effect independent of leptin signaling.

• Journal of Preventive Medicine and Public Health
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• v.40 no.1
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• pp.71-76
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• 2007

Objectives : This study was performed to investigate the distribution of apolipoproteins A-I and B among Korean employees and their partners. Methods : The study population consisted of 7,633 men and women (4,578 men and 3,054 women) residing in Seoul and Kyung-gee Do, with an average age of $43.5{\pm}8.3$ years. Blood samples were collected following at least 12 hours of fasting. Apolipoproteins A-I and B were measured using a Behring Nephelometer analyzer. The body mass index (BMI) for each participant was calculated as weight (kg) divided by height squared $(m^2)$. Information on health-related behaviors such as exercise, alcohol intake, and smoking habits was collected through self-administrated questionnaires. Results : The mean concentrations of Apo A-I were $132.6{\pm}22.3mg/dL$ and $142.9{\pm}24.8mg/dL$ in the men and women, respectively. The concentration of Apo A-I increased significantly across all age categories of men. The mean concentrations of Apo B were $101.7{\pm}23.2mg/dL$ and $87.8{\pm}23.5mg/dL$ in the men and women, respectively, and Apo B increased significantly across all age categories for both the men and women. Exercise and BMI were major determinants for Apo A-I and B levels. The 10th percentile of Apo A-I concentration was 109 mg/dL in the men and 113 mg/dL in the women, and the 90th percentile of Apo B concentration was 131 mg/dL in the men and 118 mg/dL women. Conclusions : For the prevention of coronary artery disease, we recommend that for individuals in the 10th percentile of concentration for Apo A-I and the 90th percentile of concentration for Apo B, active preventive interventions such as weight loss and exercise should be taken. This study, within its limitations, may be useful for evaluating apolipoprotein A-I and B concentrations in Korean adults.

• Journal of the Korean Applied Science and Technology
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• v.26 no.1
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• pp.102-108
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• 2009

Behaviors of saturated fatty acid halides (CI4, C16, C18) were measured by LB method when the molecules were stimulated by pressure. The saturated fatty acid halides were deposited on the indium tin oxide(lTO) glass by the LB method. The average organic ultra thin film size and the surface roughness of the fatty acid halides thin films were investigated using AFM. It was found that AFM images show small surface roughness ($2.5{\sim}5.0\;nm$) and the organic ultra thin film size of $2.5{\sim}12\;nm$. Both aggregations and pin-holes were also seen on the AFM images. However we found that the surface roughness. These effects seem to be reasonable to be related to the increase of the organic ultra thin film size of fatty acid halides.

• Textile Coloration and Finishing
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• v.5 no.3
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• pp.194-205
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• 1993

Plasma polymerization in prepared glow discharge was carried out to improve the bathochromic of dyed PET fabrics by using silicon containing vinyl monomer in plasma polymerization equipment which consists of a pair of electrodes was connected to the 13.56MHz RF generator. The optimum condition for the bathochromic effect was investigated on various plasma polymeriztion parameters. By plasma polymerization used silicon containing vinyl monomer, the bathochromic of dyed PET fabrics was very enhanced. The optimum conditions on this equipment were as follows ; electrode distance : 3cm, discharge output : 60W, gas pressure : 0.3 Torr, monomer flow rate : 30㎤/min. plasma polymerization time : 60sec. The apparent strength of plasma polymerized PET fabrics was increased about 40∼47% with decreasing about 3 of L value.

• Journal of The Korean Association For Science Education
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• v.11 no.2
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• pp.67-77
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• 1991

In this paper, current research papers on Physics Problem Solving were analyzed according to the types of research purpose, method, subject and content of Physics, by using 3 Proceedings and 4 kinds of Journal, that is, the International Workshop(1983, Paris, France) and Conference (1983, Utrecht, The Netherlands) and Seminar(1987, Cornell University, U. S. A.) on Physics Education, and Journal of Research in Science Teaching (1984-1990) and Science Education (1986-1990). and Inter national Journal of Science Education(l987-1988) and Cognitive Science(1989-1990). There were 98 research papers on Problem Solving and among them 37 papers on Physics Problem Solving were selected for analyzing. The results of analysis are as follows; 1) The studies on Model of Novice Student were 22(59%), And those on Model of Desired Preformance, on Model of learning and on Model of Teaching were all much the same. 2) The theoretical studies were 10(27%), and the experimental ones 27(73%). Among the experimental studies, there were 16(59%) by using the written test, and 7(26%) by using the thinking aloud method. 3) The studies about university students as subjects were 20(54%). Probably, it seems the reason that most of researchers on Physics Problem Solving were professors of university or graduate students. 4) Among the various fields of Physics, the studies on Mechanics were 24(63%) and those on E1ectromagnetics 6(16%). or graduate students.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.4
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• pp.503-513
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• 2007

The obese population has been increasing worldwide and obesity has become one of the socioeconomic problems. Obesity raises more concerns as more studies regarding its direct and indirect relativity to several diseases such as type II diabetes, hypertension, etc. are published. Since leptin, an important signal in the chronic control of food intake and energy expenditure, was discovered in 1994, there has been a great accumulation of knowledge on fighting obesity by facilitating pharmacological and nutritional strategies on the molecular level of the body weight control system. In particular, evidences are accumulating that particular food components affect our physiological function and gene expressions which are associated with body weight control. In this study, we review the four mechanisms for weight control and antiobesity functional agents such as HCA, L-carnitine, CLA, chitosan, calcium supplements capsaicin contained in red pepper, and oriental herbal mixture. We also describe about the efficacy and working mechanism of these functional agents on the basis of antiobesity mechanisms.

• Transactions on Electrical and Electronic Materials
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• v.11 no.3
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• pp.145-148
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• 2010

White organic light emitting devices were fabricated to improve the stability through a structural change using the two peak emission method. The fabricated devices were composed of indium tin oxide (100 nm)/ $\alpha$-NPD (30 nm)/4,40-bis(2,20-diphenylvinyl)-1,10-biphenyl (DPVBi, d: variable)/DPVBi: Rubrene (40 nm)/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline(5 nm)/ $Alq_3$(5 nm)/ Al (100 nm). A DPVBi for blue emissions was used as the host material in the emitters. The doping concentration of the Rubrene was fixed at 2.0% (by weight). The white emission with Commission Internationale De L'Eclairage coordinates of (0.3342, 0.3439) occurred at 14 V with a thickness d of 1 nm. It was insensitive to the drive voltage, and the devices had a maximum luminance of $211\;cd/cm^2$. At 19 V, the current density and maximum external quantum efficiency were $173\;mAcm^2$ and 0.478%, respectively.

• Animal Systematics, Evolution and Diversity
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• v.22 no.2
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• pp.223-229
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• 2006

Two litonotid ciliates collected from the freshwater habitats in Korea were identified as Loxophyllum meleagris ($M\ddot{u}ller$, 1773) and Siroloxophyllum utriculariae (Penard, 1922). The description was based on the observation of living and protargol impregnated specimens, and biometric analysis. Their diagnostic characteristics are as follows. L. meleagris; $163-480\times80-100{\mu}m$ in vivo, body shape lancet or knife-like; dorsal margin with 10-19 extrusome warts; 8-35 macronuclei nodules, like a string of bead; 16-21 somatic kineties on right side (including perioral kinety 2, 3) and 6-11 on left side (including perioral kinety 1); 1 contractile vacuole located at posterior part at diastole stage, extending along the dorsal margin toward anterior end with a single long narrow canal. S. utriculariae; $110-170\times78-150{\mu}m$ in vivo, body shape lancet like; dorsal margin without extrusome warts; 2 macronuclei, spherical; 12-19 somatic kineties on right side, 3-7 on left side (including perioral kinety 1); 2-3 contractile vacuoles, first one located anterior ventrally, second one located posterior dorsally and last one located near posterior end of cell.

• Clean Technology
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• v.7 no.1
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• pp.35-42
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• 2001

This study was performed to evaluate the effect of zeolite addition on biofloc in aictvated sludge process. Two units were compared each other, in which one was operated as control unit (CU) and the other was managed by adding zeolite into aeration basin to sustain 4,000 mg/l (ZU). It was observed that flocs of both units were enduringly increased in medium size by extending SRT (Solid Retention Time), although their effect size of ZU was smaller than theirs of CU. Zeolite application excessively improved sludge settling property and ZU presented sludge settling velocity of 3.4 to 11 m/h regardless of SRT variation. The sludge volume index (SVI) was in the range of 50 and 108 ml/g. Conversely, the sludge settling velocity of CU seriously depended on SRT increase, and sludge sedimentation was not achieved at a 40 days of SRT due to Sphaerotilus appeared predominantly in reactor.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.10
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• pp.4055-4068
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• 2010

In this study, validity of wastewater treatment system with advanced treatment processes was evaluated by studying its operational conditions by applying the advanced treatment to the wastewater treatment system which was operating for last several years. Study indicated a fair result for the removal efficiencies of BOD, T-P, and T-N for each unit operation. BOD removal efficiencies for primary clarifier, bioreactor, final effluent are 35, 87, and 48 % respectively. T-P(T-N) removal efficiencies for primary clarifier, bioreactor, final effluent are 18(23), 40(38), and 25(25) % respectively. Further investigation of bioreactor showed that various microorganism such as bacteria, protozoa, and metazoa is present in the bioreactor, and the main function of the media, adhesion (adsorption) of microorganism onto the media, is stabilized. Final effluent quality was lower than the regulation, and BOD, COD, SS, T-N, T-P were 5.5, 9.9, 4.6, 11.8, 0.99 mg/L respectively.