• Title/Summary/Keyword: soft contact

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Biosafety of the New Soft Contact Lens Materials in the Fibroblast L-929 Cell Line (흰쥐의 섬유아세포 L-929를 이용한 새로운 Soft Contact Lens 소재의 생물안전성 검증)

  • You, Young-Hyun;Nam, Joo-Hyeung;Kim, Bieong-Kil;Kim, Soon-Bok;Moon, Ik-Jae;Kim, Jong-Pil;Seu, Young-Bae
    • Microbiology and Biotechnology Letters
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    • v.37 no.1
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    • pp.75-79
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    • 2009
  • In this study, we polymerized new materials for soft contact lens using HEMA (2-hydroxyethyl methacrylate) which is the based-monomer of soft contact lens, EGDMA (ethylene glycol dimethacrylate) as cross linkage agent, and the new additives of monoester or di-ester derived from itaconic acid commercially produced by the fermentation of Asp. itaconicus. New polymer materials for soft contact lens were synthesized with the mixture of HEMA and mono- or diester at different ratios and presented to a good water content and oxygen transmissibility (Dk/L) values. In case of polymerization with HEMA and mono-ester (15%), the water content and oxygen transmissibility of contact lens were found to be good values at 57.6% and 28.5 Dk respectively. The mixture of HEMA and mono-ester is more excellent than HEMA/di-ester in the water content and oxygen transmissibility. The toxicity of new contact lens materials were confirmed in the fibroblast L-929 cell line using a agar overlay test and a growth inhibition test with the extract solution of contact lens.

Elution Properties of Naringin from Soft Contact Lens Containing Naringin (나린진(naringin)이 함유된 소프트 콘택트렌즈에서 나린진의 용출 특성)

  • Ryu, Geun-Chang;Jun, Jin;Jin, Moon-Seok;Chae, Soo-Chul;Kim, In-Suk
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.3
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    • pp.45-50
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    • 2008
  • Purpose: A soft contact lens was manufactured by adding naringin known as natural anti-bacterial material to resin solution. With solution eluted from manufactured contact lens, we examined its optical properties, physical and chemical states of naringin in the polymer, and elution properties. Methods: The soft contact lens with naringin was synthesized by bulk polymerization method. IR spectrum and HPLC were used to define the bonding type of naringin itself in the soft contact lens contained naringin, elution process of naringin to the saline solution, and the amount of naringin solution eluted from the lens with elapsed time. Results: Naringin was continuously eluted with constant concentration from the soft contact lens for about a month and the structure ofnaringin which is eluted was as same as before it was added to resin solution. Any change in optical properties such as transmittance couldn't be found. Bonding state and the structure of naringin in contact lens were explained with IR spectrum and HPLC results. Conclusions: In the contact lens with naringin, naringin remained in the contact lens bonding with weak hydrogen bonding and/or van der Waals force between naringin and polymer. Naringin was continuously eluted from the contact lens contained naringin during about 1 month. Even after 1 month, it showed that the concentration of the naringin eluted was approximately 10 ppm in a day. From the results, adding naringin to the soft contact lens resin is very effective method for manufacturing the soft contact lens which has anti-bacterial function for a period of time.

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Analysis of Rolling Contact Fatigue of Ball Bearing with Various Hardness by X-ray Diffraction (BEARING소재 경도에 따른 구름접촉피로의 X선적 해석)

  • 이한영
    • Tribology and Lubricants
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    • v.17 no.3
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    • pp.209-215
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    • 2001
  • In view of the effects of the hardness of material on fatigue, rolling contact fatigue process in hard metals seems to differ from it in soft metals. This paper has been aimed to compare the rolling contact fatigue process according to the hardness of materials. Rolling contact fatigue tests using the ball bearings assembled with the inner race of four different hardness have been carried out. In addition, residual stress and half-value breadth on/below the inner raceway during individual rolling contact fatigue have been measured by X-ray diffraction. The results of this study showed that the change of residual stress and half-value breadth during the rolling contact fatigue on race way in hard metals is the same as in soft metals. However, plastic deformation by rolling contact in hard metals is in microscopic scale but only for soft metals in macroscopic scale.

Comparison of Contrast Sensitivity Between Soft Contact Lens Wearers and Spectacle Wearers (콘택트렌즈와 안경 착용자의 대비감도 비교)

  • Kim, Jai-Min;Lee, Min-Ah
    • Journal of Korean Ophthalmic Optics Society
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    • v.12 no.4
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    • pp.119-125
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    • 2007
  • The aim of the present study was to compare the contrast sensitivity of soft contact lens wearers, spectacle wearers or emmetropia. Seventy myopic eyes and thirty emmetropic eyes aged 19 to 26 years were collected. The myopic group included 48 eyes corrected with spectacle lenses and 22 eyes of them corrected with contact lenses, too: all had corrected vision acuity of 20/20 or better. Spatial contrast sensitivity was measured using the OPTEC 6500 contrast sensitivity view-in tester included the EyeView  Functional Vision Analysis software at photopic or mesoopic condition. There was no significant difference in contrast sensitivity between spectacle lenses and emmetropes. Myopes corrected with soft contact lenses showed statistical sensitivity losses at 1.5, 12 cycle/degree spatial frequencies. In conclusion, our findings suggest that loss of contrast sensitivity in soft contact lens wearers might be interpreted as evidence for corneal disruption before corneal pathological events occur in contact lens wearers. Contrast sensitivity testing appears to be a useful method for evaluating soft contact lenses.

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Microbe Pollution Condition on Soft Contact Lenses (소프트 콘택트렌즈에서의 미생물 오염양상)

  • Han, Sun-Hee;Park, Sung-Min;Yu, Tae-Shick
    • Journal of Korean Ophthalmic Optics Society
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    • v.10 no.4
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    • pp.313-321
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    • 2005
  • To know the pollution level concerning the microbes contamination condition in soft contact lenses, 2 experiments were operated with different methods. Firs experiment, we observed lenses surfaces through a scanning electronic microscope after pollution sort contact lenses with the suspensions of Staphylococcus aureus, Pseudomonas aeruginosa and Entrobacter aerogenes which can be major bacteria causing keratitis as wearing on soft contact lenses. As 1 hour after pollution with the soft contact lenses, we observed that many bacteria adhered to the lenses, and the pollution condition got worse with passing time increase(2, 4, 6, 12, and 24 hours, respectively). At 12 hours lapse of polluting soft contact lenses with P. aeruginosa, some bacteria adhered to the lenses. And as 24 hours lapsed after pollution soft lenses with E. aerogenes, bacteria adhered to them, and atypical substance was observed some of the surface of lenses. Second experiment, we observed the microbe pollution condition in soft contact lenses by let 21 people in twenties(men & women), who doesn't eye disorders, wear soft contact lenses during 4 hours. As the result, many kinds of bacterium and fungus were observed, and especially, the bacteria could be identified with their colors and the shapes of colony, so we found that single type, two types, and three types of bacteria adhered to their lenses.

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Dextrous Manipulation Planning of Soft-Fingered Hands (소프트핑거 로봇손의 물체 운용계획)

  • 정낙영;최동훈;서일홍
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.18 no.8
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    • pp.2016-2025
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    • 1994
  • A hierarchical planning strategy for dextrous manipulation of multifingered hands with soft finger contact model is proposed. Dextrous manipulation planning can be divided into a high-level stage which specifies the position/orientation trajectories of the fingertips on the object and a low-level stage which determines the contact forces and joint trajectories for the fingers. In the low-level stage, various nonlinear optimization problems are formulated according to the contact modes and integrated into a manipulation planning algorithm to find contact forces and joint velocities at each time step. Montana's contact equations are used for the high-level planning. Quasi-static simulation results are presented and illustrated by employing a three-fingered hand manipulating a sphere to demonstrate the validity of the proposed low-level planning strategy.

A Study on Protein Adsorption-resistant Soft Contact Lens (단백질흡착을 막는 소프트콘택트렌즈에 관한 연구)

  • 조종수;정영일
    • Journal of Biomedical Engineering Research
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    • v.17 no.3
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    • pp.291-296
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    • 1996
  • Poly(ethylene glycol)(PEG) macromers terminated with diacrylate Iyoups and interpenetrating poly- mer networks(IPN) composed of poly(hydroxyethyl methacrylate)(PHEMA) or poly(hydroxyethyl methacrylate-co-hydronypropyl methacrylate-co- N-vinyl pyrrolidone ) [ P( HEM A-co- HPM A-co- NVP) ] and PEG macromer were synthesized with the aim of obtaining protein adsorption resistant soft contact lens. Polymerization of PEC macromer resulted in the formation of cross-linked gels due to the multifunctionality of macromer. Crosslinked P(HEMA) or P(HEMA-co-HPMA-co-WVP) chains were interpenetrated into the cross-linked three-dimensional networks of PEG. It was found that albumin adsorption onto the contact lens prepared by P(HEMA-co-HPMA-co-NVP) /PEG IPW decreases with an increase of molecular weight of PEG. Also, it was found that albumin adsorption onto the both contact lens decreases with an increase of concentration of PEC macromer in the IPN preparation. There are also more adequate in the bioinertnen for the contact lens by P(HEMA)/PEG IPN or P (HEMA-co-HPMA-co-NVP)/PEG IPN than that by P(HEMA) or P(HEMA-co-HPMA-co-NVP)

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A Survey about Wearing Soft Contact Lenses for Astigmatism Correction of The Local College Students, Gyeongsangnam-Do, Korea (경남지역 대학생들의 난시 교정용 소프트 콘택트렌즈의 착용에 관한 설문조사)

  • Kim, Bong-Hwan;Han, Seon-Hee;Kim, Dae-Hyeon;Byeon, Sang-Hyeon;Chae, Jeong-Im;Kim, Jae-Seok;Hwang, Yun-Jeong;Kim, Hak-Jun
    • Journal of Korean Clinical Health Science
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    • v.3 no.3
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    • pp.378-389
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    • 2015
  • Purpose. The actual status of wearing toric soft contact lenses was investigated to learn why it is not used although it is required. Materials and Methods. This study has studied 64 contact lens wearing the local college students, Gyeongsangnam-do who are 20.17(${\pm}0.70$)years old, by measuring their refractive power and over-refractive power with auto refractometer(HRK-8000A, Huvitz, Korea). In addition to that, a survey was done to figure out why they do not wear toric soft contact lenses, the purpose of using toric soft contact lenses, whether they have astigmatism or any knowledge about it, the kinds of contact lens, whether they are willing to buy corrective lenses, and how they are satisfied after purchasing them. Results. 17 students (21.9%) said they experienced light-spread; 9 students (14.1%)said that they have dizziness when they wear contact lens all day long. In the survey to see whether they had astigmatism or not, 37 students (57.8%) said they had it. For the reason they do not wear toric soft contact lenses, 33 students (51.6%) said that "they were prescribed regardless of astigmatism in the optometrist." To the question asking if they are willing to buy toric soft contact lenses according to the existence of astigmatism, 51 students (79.6%) answered they are. 31 students (48.4%) said they heard a description about astigmatism at the time of purchase for contact lens. Conclusion. As the ways for any people who need to correct astigmatism to wear corrective lens, enough education about astigmatism and consistent follow-up management are needed, where the role of optometrist is considered important.

Contrast Sensitivity and Glare with Spherical and Toric Soft Contact Lenses in Low-astigmatic Eyes (구면과 토릭 소프트 렌즈로 교정한 약도 난시안의 대비감도와 눈부심)

  • Lee, Min-Ah;Kim, Hyun Jung;Kim, Jai-Min
    • Journal of Korean Ophthalmic Optics Society
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    • v.14 no.1
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    • pp.39-45
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    • 2009
  • Purpose: The purpose of this study is to compare the visual performance by contrast sensitivity (CS) and disability glare (DG) in low astigmatic eyes corrected with toric soft lenses and other optical corrections. Methods: Twenty university students with myopia (-1.00 to -6.50D Sph. with astigmatism up to 1.50 cyl) were enrolled and corrected by five different methods: 1) soft toric lenses; 2) spherical soft contact lenses; 3) RGP lenses; 4) best spectacle corrected visual acuity; 5) spherical equivalent spectacles. All subjects had corrected vision acuity of 20/20 or better. Contrast sensitivity and disability glare were measured using the OPTEC 6500 contrast sensitivity view-in tester included the EyeView Functional Vision Analysis software at photopic or mesopic conditions with glare. Results: At photopic condition, best corrected spectacle wearers had the highest monocular contrast sensitivity at all spatial frequency followed by soft toric lenses, RGP lenses, spherical equivalent spectacles, and spherical soft contact lenses. However, all of them were in normal contrast sensitivity value at photopic condition. At mesopic condition with glare, toric soft lenses were the highest and followed by RGP lenses, spherical equivalent spectacles, best spectacle corrected visual acuity and spherical soft contact lenses. It was observed that spherical soft contact lens wearers demonstrated lower range than normal contrast sensitivity value at mesopic condition with glare. Conclusion: Toric soft lenses gave better visual performance than spherical soft lenses in low astigmatic eyes. Subjects requiring the use of contact lenses under mesophic conditions could benefit from toric soft lenses.

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The Relationship between Habitual Patient-Reported Symptoms and Signs in the Soft Contact Lens Wearers (소프트 콘택트렌즈 착용자에서 평상시 나타난 증상에 관한 연구)

  • Lee, Koon-Ja;Buyn, Jang-Won;Mun, Mi-Young;Leem, Hyun-Sung
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.3
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    • pp.19-28
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    • 2008
  • Purpose: To understand symptoms and signs in soft contact lens wearers the authors evaluate the attribution of the tear test to the contact lens related symptoms and signs. Methods: Sixty-two healthy soft contact lens wearers (23.95${\pm}$4.38 years old, 18.60${\pm}$16.92 months of prior lens wear) were participated in this study. 3 kinds of tear test and McMonnies' questionnaire test were performed for the soft contact lens wearers and subjective symptoms and objective signs were graded using CCLRU scales during the study period. Results: In this surveys, we found ocular dryness, redness and tiredness are the most common frequent and severe symptoms in soft contact lens wearers. Frequency of the ocular dryness, redness and tiredness are associated with grittiness, burning sensation and foreign body sensation respectively, and severity of the photophobia, foreign body sensation are associated with unstable vision and grittiness and which are associated with score of McMonnies' Questionnaire. Conjunctival redness and limbal redness are major signs but those are not need to be clinical care and rarely occurred corneal and conjunctival staining which are associated with tear break-up-time statistically. Conclusions: Dryness, redness and tiredness are primary common symptoms in Korean soft contact lens wearers. The frequency of those symptoms are increased with the period of soft contact lens wear and those are associated with other symptoms but have no relationship with signs.

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