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Effects of Different Methods for Determining the Number of Transferable Embryos on Genetic Gain and Inbreeding Coefficient in a Japanese Holstein MOET Breeding Population

  • Terawaki, Y.;Asada, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.5
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    • pp.597-602
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    • 2001
  • This study was conducted to examine the relationships between the methods used to determine the number of transferable embryos collected per flush and the estimated cumulative genetic improvements in the Japanese Holstein MOET breeding population. Cumulative genetic improvements were predicted by Monte Carlo simulation using three different determination methods (MODEL 1, MODEL 2, and MODEL 3), for calculating the number of embryos collected per flush. Moreover EBVs were estimated including or ignoring coefficients of inbreeding in MME. Inbreeding coefficients were also predicted. The number of transferable embryos was determined using normal, gamma, and Poisson distributions in MODEL 1, gamma and Poisson distributions in MODEL 2, and only the Poisson distribution in MODEL 3. The fitness of MODEL 2 in relation to field data from Hokkaido Japan was the best, and the results for MODEL3 indicated that this model is unsuitable for determining the number of transferable embryos. The largest cumulative genetic improvement (3.11) in the 10th generation was predicted by MODEL 3 and the smallest (2.83) by MODEL 2. Mean coefficients of correlation between the true and estimated breeding values were 0.738, 0.729, and 0.773 in MODELS 1, 2, and 3, respectively. It is suggested that the smallest genetic improvement in MODEL 2 resulted from the smallest correlation coefficient between the true and estimated breeding values. The differences in milk, fat, and protein yields between MODELS 2 and 3 were 182.0, 7.0, and 5.6 kg, respectively, in real units when each trait was independently selected. The inbreeding coefficient was the highest (0.374) in MODEL 2 and the lowest (0.357) in MODEL 3. The effects of different methods for determining the number of transferable embryos per flush on genetic improvements and inbreeding coefficients of the simulated populations were remarkable. The effects of including coefficients of inbreeding in MME, however, were unclear.

Assessment of Autonomic Function in Functional Headache by Heart Rate Variability (심인성(心因性) 두통(頭痛)의 심박변이도(HRV) 분석에 의한 자율신경기능 평가)

  • Kim, Kyung-Ok;Song, Ji-Hyung;Kim, Geun-Woo;Koo, Byung-Soo;Shim, Sang-Min
    • Journal of Oriental Neuropsychiatry
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    • v.13 no.1
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    • pp.19-37
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    • 2002
  • Objectives : This study sought to define autonomic functional difference on heart rate variability between headache patients and normal subjects Methods : We determined, heart rate variability of 52 headache patients and 30 normal subjects by means of three time domain measures: Mean PR(mean pulse rate), SDNN(standard deviation of all normal R-R intervals), RMSSD(the square root of the mean of sum of the squares of differences between adjacent normal R-R intervals), and five frequency domain measures: TP(total power), VLF(very low frequency), LF(low frequency), HF(high frequency). Results : 1) RMSSD, TP, HF, HF Norm of HRV decreased with aging and LF Norm, LF/HF increased with aging in headache patients. 2) There was no significant differences between migraine and tention headache in any standard index of HRV, whereas, HRV of total headache patients were smaller than those of normal subjects. 3) In the gender comparison, SDNN, RMSSD, HF of tention headache patients were the smallest and then migraine patients, normal subjects in order with man, whereas, LF Norm, LF/HF of normal subjects were the smallest with man. RMSSD of migraine patients were the smallest and then tention headache patients, normal subjects in order with women. 4) In the term of history of headache patients, SDNN, RMSSD were getting lower as long term. 5) There was no significant differences of HRV in physical symptom of headache patients. Conclusions : All of these results show that standard index of HRV of headache patients were significantly different with normal subjects.

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Effect of the Structure of the Smallest Poresize Layer on the Permeability of PES Microfiltration Membranes (최소 기공층 구조가 PES계 정밀여과막 투과 성능에 미치는 영향)

  • Kim, No-Won
    • Membrane Journal
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    • v.19 no.1
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    • pp.25-33
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    • 2009
  • PES (polyethersulfone) membranes with highly enhanced their asymmetry were prepared by phase inversion process. The membranes were prepared by using PES/DMF (N,N-dimethylformamide)/TSA (p-toluenesulfonic acid)/PVP (polyvinylpyrrolidone) casting solution and water coagulant. The pre-coagulation of membrane surface which was induced by an addition of TSA as a demixing agent and PVP as a swelling polymer in the PES solution and humid exposure time, played a crucial role in determining morphological properties and the PWP (pure water permeation) performance. The PES solution was coated on polyester film under condition of 80% humidity for a while ($72{\sim}144$ sec) before immersing in a coagulation bath. The characterization of membranes was carried out by a capillary flow porometer, a FE-SEM and a permeation test apparatus. As the thickness of the smallest pore size layer (SPL) decreased, the asymmetry of membrane increased under conditions of 20 wt% of TSA and 10 wt% of PVP in 11 wt% of PES solution during longer humid contact time. As a result, the membranes showed a remarkable increase of PWP.

An Investigation of the Effect of the Height of Wteps on the Joint Moment of Lower Extremities of the Elderly While Walking Downstairs (노인의 계단 내려가기 동작 시 계단 높이와 하지 관절 모멘트와의 관계 연구)

  • Eun, Seon-Deok
    • Korean Journal of Applied Biomechanics
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    • v.16 no.4
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    • pp.31-38
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    • 2006
  • The purpose of this study was to investigate the effect of changing the steps height on the joint moment of lower extremity in stair-descent activity of elderly persons. Data were collected by 3-D cinematography and force platform. 9 male elderly subjects in the 60s and 70s participated in this study. All subjects performed a stair-descent in four different heights of stairs (10, 14, 18, 22cm) having 5 step staircase. The results were as follows. 1. For the step height of 22cm the maximum. plantarflexion moment was the smallest and the largest for the step height of 14cm. 2. There was not a statistical difference shown for the extension moment of the knee joint for the different height of steps. 3. There was not a statistical difference shown for the flexion moment of the hip joint for the varying height of steps but on average for the 18cm step this increased rapidly. 4. The smallest maximum. value for inversion moment was revealed for the step height of 10cm and this increased significantly for the step height of 22cm. 5. The smallest maximum. value for abduction moment of the hip joint was revealed for the step height of 10cm and this increased significantly for the step height of 22cm. 6. There was no significant difference shown for the maximum. abduction moment for the hip joint. The main conclusion is that there is a huge difference in the moment of the lower extremities for the elderly while walking down a stairs with a step height above 18 cm and that this moment increased or decreased rapidly under a condition of step height being 22cm. With the results from this research and related research of elderly walking upstairs it can be shown that the step height has a large role in the safety for the elderly.

A PAPR Reduction Method Using the Correlation of the OFDM Information Signal (정보의 상관도를 이용한 OFDM신호의 PAPR저감 기법)

  • Kim Sang-Woo;Hieu Nguyen Thanh;Ryu Heung-Gyoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.16 no.3 s.94
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    • pp.327-334
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    • 2005
  • In this paper, a new PAPR reduction method using correlation of input data sequence is proposed in order to overcome the serious drawbacks, such as necessity of side information transmission or increase of system complexity and calculation which are the basis of previous SLM, PTS and DSI method. A new PAPR reduction method can be classified into Method 1 and Method 2. Method 1 reduces the correlation between the smallest sub-sequence and neighbor smallest sub-sequence. And, to consider the own correlation in detail, the Method 2 reduces two case of correlation between neighbor smallest sub-sequences and neighbor largest sub-sequences. According to simulation result, Method 1 and Method 2 has about 0.5 $\~$ O.8 dB and 1 $\~$ l.2 dB PAPR reduction effect respectively. If more detailed process to reduce the correlation of input data sequence is considered, we can achieve better PAPR reduction performance.

Grip Force, Finger Force, and Comfort analyses of Young and Old People by Hand Tool Handle Shapes (수공구 손잡이 형태에 따른 청.노년층의 악력과 손가락 힘 및 편안함 분석)

  • Kong, Yong-Ku;Sohn, Seong-Tae;Kim, Dae-Min;Jung, Myung-Chul
    • Journal of the Ergonomics Society of Korea
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    • v.28 no.2
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    • pp.27-34
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    • 2009
  • The purpose of this study was to evaluate aging (young and old), gender (male and female), and handle shape effects on grip force, finger force, and subjective comfort. Four handle shapes of A, D, I, and V were implemented by a multi-finger force measurement (MFFM) system which was developed to measure every finger force with different grip spans. Forty young (20 males and 20 females) and forty old (20 males and 20 females) subjects participated in twelve gripping tasks and rated their comfort for all handles using a 5-point scale. Grip forces were calculating by summation of all four forces of the index, middle, ring and little fingers. Results showed that young males (283.2N) had larger gripping force than old males (235.6N), while young females (151.4N) had lower force than old females (153.6N). Young subjects exerted the largest gripping force with D-shape due to large contribution of the index and middle fingers and the smallest with A-shape; however, old subjects exerted the largest with I-shape and the smallest with V-shape due to small contribution of the ring and little fingers. As expected, the middle finger had the largest finger force and the little finger had the smallest. The fraction of contribution of index and ring fingers to grip force differed among age groups. Interestingly, young subjects provided larger index finger force than ring finger force, whereas old subjects showed that larger ring finger forces than index finger force in the griping tasks. In the relationship between performance and subjective comfort, I-shape exerting the largest grip force had less comfort than D-shape producing the second largest grip force. The findings of this study can provide guidelines on designing hand tool handle to obtain better performance as well as users' comfort.

Nephelometer Measurement of Aerosol Scattering Coefficients at Seoul (네펠로미터로 관측한 서울의 에어러솔 산란계수 특성)

  • Shim, Sungbo;Yoon, Young Jun;Yum, Seong Soo;Cha, Joo Wan;Kim, Jong Hwan;Kim, Jhoon;Lee, Bang-Yong
    • Atmosphere
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    • v.18 no.4
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    • pp.459-474
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    • 2008
  • Aerosol scattering coefficients for three different wavelengths ($\lambda$=450,550,700 nm) are measured almost continuously by a nephelometer in Seoul for a period of 13 months (February 2007-February 2008), which includes two weeks break in August 2007 for measurements at Daegwallyeong and YoungJongdo. The mean of the daily average scattering coefficients at $\lambda$=550 nm is $194.1{\pm}144.2Mm^{-1}$ and the minimum and maximum are $14.3Mm^{-1}$ and $998.1Mm^{-1}$, respectively. The scattering coefficient shows a general increasing trend with atmospheric relative humidity (RH). When the data are classified according to weather conditions, the days with no major weather events show the smallest scattering coefficient and also the lowest RH. Surprisingly haze/fog days show the largest scattering coefficient and Asian dust days comes in second. Although the variation is large within a season, winter shows the largest and autumn shows the smallest scattering coefficient. The average ${\AA}ngstr{\ddot{o}}m$ exponent is $1.40{\pm}0.32$ for the entire Seoul measurement. As expected, Asian dust days show the smallest ${\AA}ngstr{\ddot{o}}m$ exponent and haze/fog days are the next, suggesting more efficient hygroscopic growth of aerosols for this weather condition. Aerosol scattering coefficient seems to show better correspondence with CCN concentration rather than total aerosol concentration, which may indicate that CCN active aerosols are also good scattering aerosols.

A Study on the Lower Body Somatotype Characteristics of 20~59 Aged Women by Age Groups

  • Lee, Mi-Sung;Kim, So-Ra
    • Journal of the Ergonomics Society of Korea
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    • v.30 no.6
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    • pp.727-737
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    • 2011
  • Objective: This study aimed to analyze somatotype characteristics of the women of 20's, 30's 40's and 50's and thus to provide the basis for developing pants patterns by the age groups. Background: Despite many previous researches for the somatotype characteristics of adult women, few studies have considered age groups. Method: The data of the $5^{th}$ anthropometry by Size Korea were analyzed for the purpose. The 32 direct body measurements and the 32 indexes of 2,213 women aged 20~59 were analyzed. In order to compare somatotype characteristics among the age groups, an ANOVA and a Tukey test were used. Results: The women in 20's were the tallest among the age groups, and had the smallest waist circumference and hip circumference. Their waist breadths were also the narrowest. They had a slim and long body type but their calves were relatively thick. The 30's women were smaller, shorter with the height and length items than the 20's were. They were bigger, wider and deeper with the circumference, breadth and depth items than the 20's were and they were heavier. On the other hand, their hip circumference and crotch length were in the same group as the women in 20's. The crotch length(omphalion) of the 40's women was the longest among all the age groups and the crotch length(natural indentation) of the 40's women was in the same as the women in 50's. The women in 50's were the smallest and heaviest among all the age groups. The difference between their hip circumferences and waist circumferences was the smallest. They had an obese abdomen and sagged hips. Conclusions: The somatotype characteristics of the age groups were significantly different, and thus it is suggested to develop skirt and pants patterns for each age group. Application: The skirt and pants patterns for the somatotype characteristics of the women by age groups will be developed through the body feature data of this study.

The effects of cryopreservation on human dental pulp-derived mesenchymal stem cells

  • Tomlin, Allison;Sanders, Michael B;Kingsley, Karl
    • Biomaterials and Biomechanics in Bioengineering
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    • v.3 no.2
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    • pp.105-114
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    • 2016
  • The purpose of this study is to evaluate the effects of cryopreservation on dental pulp-derived stem cells (DPSC) viability over a period of three years. Dental pulp-derived stem cells were isolated and cultured from thirty-one healthy teeth. DPSC isolates were assessed for doubling-time and baseline viability prior to cryopreservation and were assessed again at three time points; one week (T1), 18 months (T2), and 36 months (T3). DPSC can be grouped based on their observed doubling times; slow (sDT), intermediate (iDT), and rapid (rDT). Viability results demonstrated all three types of DPSC isolates (sDT, iDT and rDT) exhibit time-dependent reductions in viability following cryopreservation, with the greatest reduction observed among sDT-DPSCs and the smallest observed among the rDT-DPSC isolates. Cryopreserved DPSCs demonstrate time-dependent reductions in cellular viability. Although reductions in viability were smallest at the initial time point (T1) and greatest at the final time point (T3), these changes were markedly different among DPSC isolates with similar doubling times (DTs). Furthermore, the analysis of various DPSC biomarkers - including both intracellular and cell surface markers, revealed differential mRNA expression. More specifically, the relative high expression of Sox-2 was only found only among the rDT isolates, which was associated with the smallest reduction in viability over time. The expression of Oct4 and NANOG were also higher among rDT isolates, however, expression was comparatively lower among the sDT isolates that had the highest reduction in cellular viability over the course of this study. These data may suggest that some biomarkers, including Sox-2, Oct4 and NANOG may have some potential for use as biomarkers that may be associated with either higher or lower cellular viability over long-term storage applications although more research will be needed to confirm these findings.

Smallest-Small-World Cellular Genetic Algorithms (최소좁은세상 셀룰러 유전알고리즘)

  • Kang, Tae-Won
    • Journal of KIISE:Software and Applications
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    • v.34 no.11
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    • pp.971-983
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    • 2007
  • Cellular Genetic Algorithms(CGAs) are a subclass of Genetic Algorithms(GAs) in which each individuals are placed in a given geographical distribution. In general, CGAs# population space is a regular network that has relatively long characteristic path length and high clustering coefficient in the view of the Networks Theory. Long average path length makes the genetic interaction of remote nodes slow. If we have the population#s path length shorter with keeping the high clustering coefficient value, CGAs# population space will converge faster without loss of diversity. In this paper, we propose Smallest-Small-World Cellular Genetic Algorithms(SSWCGAs). In SSWCGAs, each individual lives in a population space that is highly clustered but having shorter characteristic path length, so that the SSWCGAs promote exploration of the search space with no loss of exploitation tendency that comes from being clustered. Some experiments along with four real variable functions and two GA-hard problems show that the SSWCGAs are more effective than SGAs and CGAs.