• 한국환경성돌연변이발암원학회지
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• 제11권2호
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• pp.148-160
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• 1991

인체의 여리 조직을 대상으로하여 면연조직화학전방법을 통하여 glutathione transferase isoenzyme의 분포를 비교 분석하였다. 상피조직중의 GST-Pi의 다랑분포가 확인되었으며, 특히 외인성 화학물질에 노출되기 쉬운 피부, 유두, 신도 등의 과립층과 췌장, 담도, 타액선, 신세뇨관등의 배설관의 상피 또는 난소의 theca와 granulosa, 고환의 Leydig세포, 부신피 질의 zona reticularis 등의 steroid 생합성이 왕성한 부위에서 높은 GST-Pi 분포가 관찰되었다. 면역조직화학적 분석과 병행하여 Western blot 분석을 시행해본 결과 이러한 GST-Pi 분포가 인체유래 유각상피세포 중에서도 확인되었다. 그러나 K-ras 암유전자로 형질전환하여 암화능을 갖춘 인체상피세포주의 GST-Pi 발현은 유의한 차이를 보이지 않았다. 뿐만아니라 타액중에서도 GST-Pi가 다량 존재함이 Western blot 분석에 의하여 구명되었다. 이러한 결과는 GST-Pi가 인체조직 중 외인성독성물질에 노출되는 부위, 내인성 steroid 합성부위 및 배설능을 갖는 부위의 상피조직에 주로 존재하고 있음을 보여주고 있으며, 이러한 GST-Pi의 조직분포는 동효소가 인체의 해독기능에 주요한 역할을 하고 있음을 시사해주고 있다.

• Toxicological Research
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• 제32권2호
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• pp.103-108
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• 2016

The purpose of this study was to determine the hair growth effects of lavender oil (LO) in female C57BL/6 mice. The experimental animals were divided into a normal group (N: saline), a vehicle control group (VC: jojoba oil), a positive control group (PC: 3% minoxidil), experimental group 1 (E1: 3% LO), and experimental group 2 (E2: 5% LO). Test compound solutions were topically applied to the backs of the mice ($100{\mu}L$ per application), once per day, 5 times a week, for 4 weeks. The changes in hair follicle number, dermal thickness, and hair follicle depth were observed in skin tissues stained with hematoxylin and eosin, and the number of mast cells was measured in the dermal and hypodermal layers stained with toluidine blue. PC, E1, and E2 groups showed a significantly increased number of hair follicles, deepened hair follicle depth, and thickened dermal layer, along with a significantly decreased number of mast cells compared to the N group. These results indicated that LO has a marked hair growth-promoting effect, as observed morphologically and histologically. There was no significant difference in the weight of the thymus among the groups. However, both absolute and relative weights of the spleen were significantly higher in the PC group than in the N, VC, E1, or E2 group at week 4. Thus, LO could be practically applied as a hair growth-promoting agent.

• 대한의생명과학회지
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• 제22권4호
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• pp.140-149
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• 2016

All pesticides must be assessed strictly whether safe or not when agricultural operators are exposed to the pesticides in farmland. A pesticide is commonly regarded as safe when estimated dermal absorption amount is lower than the acceptable operator's exposure level (AOEL). In this study, dermal absorption rate of chlorpyrifos, a widely used organophosphate insecticide, was investigated using rat dermal tissue model. Chlorpyrifos wettable powder solved in water (250, 500 and 2,500 ppm) was applied to freshly excised rat dermal slices ($341{\sim}413{\mu}m$ thickness) on static Franz diffusion cells at $32^{\circ}C$ for 6 hours. After exposure period of 6 hours, and then washing-at residual amount of chlorpyrifos was analyzed in dermal tissues, tape strips, washing solution, washing swabs of receptor bottles and receptor fluids at 1, 2, 4, 8 and 24 hours. Chlorpyrifos was only detected in dermal tissue but not found in receptor fluid at each concentration and time point, and the absorption rate of 250, 500 and 2,500 ppm was 2.36%, 1.96% and 1.69%, respectively. The estimated exposure level of chlorpyrifos was calculated as 0.012 mg/kg bw/day. The health risk for farmers in this condition is a level of concern because the estimated exposure level is 12 times higher than AOEL 0.001 mg/kg bw/day. However, actual health risk will be alleviated than estimated because absorbed chlorpyrifos is not permeated into internal body system and only retained in skin layer.

• 복식
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• 제59권3호
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• pp.82-95
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• 2009

The kind and the use of the fabrics for crown manufacture in the Baekje period has been studied by characterizing the imprinted fabrics on the crowns and the diadem ornaments from the old tomb. The contact region with the skin inside of the crown and the region between the bark of white birch and the gilt bronze openwork plates contained fabrics. The fabrics used in the gilt-bronze crown were all plain weave silk except that of Yongwonri tomb where loosely woven thin tabby was used. There have been 4-types of iron framed diadem of the Baekje, which comprise the inverted triangle-shaped diadem only with iron frame, the diadem with gold plate ornament in the iron frame, the diadem decorated with mica plate and gold plate, and the diadem with silver ornament in the iron frame. The fabrics used in the triangle shaped iron frame diadem include plain weave silk, irregular plain woven silk, thin tabby, complex silk gauze, twill weave on plain ground, and warp-faced compound weave. The iron frames were wrapped with the fabrics from one layer up to three layers, and the iron diadem was covered with one later of loosely woven textile such as irregular plain woven silk, thin tabby, and complex silk gauze. But in case of decorating the iron diadem with gold Plate ornaments, multiple layers of fabric were used to sustain the weight of the ornaments. The fabrics in the iron diadem frame were sewed with running stitch, overedge stitch or hemming stitch, diagonal hemming stitch, half back stitch), and overcast stitch.

• 한국의류학회지
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• 제41권5호
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• pp.929-938
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• 2017

This research investigated the effects of cool touch fabrics on thermo-regulating physical properties and subjective evaluation using a 3D fitted women's T-shirts in wear test. Qmax, clothing microclimate, microclimate wettedness, thermogram and subjective vote were observed during rest-right after an exercise-rest protocol. As a result, there was no single determining physical variable to explain the reasons of cool sensations of T-shirts made of cool touch fabric across the entire protocol. Qmax could partly predict a wear sensation at the initial stage when only insensible perspiration was presented. Simultaneous observation of temperature/humidity gradient understand from the inside to the outside of the clothing layer or microclimate wettedness calculated using vapor pressure were helpful to figure out the performance of cool touch fabric, especially at the later stage of the protocol when sweating was excessive. It was especially difficult to connect thermo-regulating physical variables to the subjective evaluation during transient conditions such as 'right after exercise' stage. It is necessary to measure the amount of heat and moisture transferred from the skin to the outside of clothing along with the physical properties measured in this study to understand the detailed mechanisms of why a cool sensation is evoked from tight fitting T-shirts made of newly developed cool touch fabrics.

• 대한약침학회지
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• 제11권2호
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• pp.33-40
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• 2008

Objective The purpose of this study was to investigate the effects of Sweet Bee Venom to the abdominal fat accumulation clinically. Methods The 20 healthy women volunteers who showed the notice of this study by the home page of Sangji University were treated with Sweet Bee Venom(SBV) during twenty times. To investigate the effects of Sweet Bee Venom of the abdominal fat accumulation, abdominal CT, LFT, Thermography, BMI, Inbody 3.0 etc. were performed during clinical trials. And statistical analysis was carried out the data of 10 volunteers who performed all the schedule of this study. Results Following results were obtained from the clinical studies Sweet Bee Venom showed the effect of decreased the body weight, thickness of abdominal skin and fat layer, BMI, and increased abdominal heat, but they are not showed statistical significant. Conclusions These results suggest that treatment Sweet Bee Venom on the abdomen was effective to decrease fat tissue but for the treatment of obesity was performed with right diet program and exercise.

• 수산해양기술연구
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• 제42권2호
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• pp.78-85
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• 2006

A survey on the fishing gear for octopus drift-line fishing was done in Gangwon-do, Sacheon, Gyeongnam and Hokkaido, Japan, while a survey on the environments of fishing grounds used data from January to August from the Korea east coast farming forecast system of Donghae Fisheries Research and Development Institute. The present situation of fishing was examined with boats engaging in drift-line fishing from March to August in the coastal waters along Gangneung. The fishing tackle for octopus drift-line fishing was made manually, and the size, shape, and weight of the hook and number of shooting used vary according to the fishing time and region. Lead is used as the material for sinkers. As bait, pork fat with skin is mostly used in Gangwon-do. The temperature of the bottom water layer in the coastal fishing ground of Gangneung from April to June ranges from $3.2-12.4^{\circ}C$, which is the optimal temperature for octopuses. During July and August, the temperature ranges from $5.0-20.6^{\circ}C$. The maximum difference between day and night temperatures reached up to $9.2^{\circ}C$. Salinity is generally stable at $33.2-35.324.6%_{\circ}$, which does not affect the inhabitation of octopuses. The octopus catch reached its peak from May to July, while most octopuses weighed less than 1 kg (76.7%). The results show that it is effective to carry out octopus drift-line fishing up to a depth of 40 meters; and that the maximum number of octopuses per line is obtained with an operation time of six hours.

• Membrane and Water Treatment
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• 제6권2호
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• pp.127-139
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• 2015

Rejection of ionic solutes by reverse osmosis (RO) and nanofiltration (NF) membranes is controlled mainly by electrochemical interaction as well as pore size, but it is very difficult to directly evaluate such electrochemical interaction. In this work, we used an inverse HPLC method to investigate the interaction between ionic solutes and poly (m- phenylenediaminetrimesoyl) (PPT), a polymer similar to the skin layer of polyamide RO and NF membranes. Silica gel particles coated with PPT were used as the stationary phase, and aqueous solutions of the ionic solutes were used as the mobile phase. Chromatographs obtained for the ionic solutes showed features typical of exclusion chromatographs: the ionic solutes were eluted faster than water (mobile phase), and the exclusion intensity of the ionic solute decreased with increasing solute concentration, asymptotically approaching a minimum value. The charge density of PPT was estimated to be ca. 0.007 mol/L. On the basis of minimum exclusion intensity, the exclusion distances between a salt and neutralized PPT was examined, and the following average values were obtained: 0.49 nm for 1:1 salts, 0.57 nm for 2:1 salts, 0.60 nm for 1:2 salts, and 0.66 nm for 2:2 salts. However, $NaAsO_2$ and $H_3BO_3$, which are dissolved at neutral pH in their undissociated forms, were not excluded.

• Advances in concrete construction
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• 제10권4호
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• pp.357-367
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• 2020

The impulse of this paper is to examine the influence of unsteady flow comprising of Eyring-Powell nanofluid over a stretched surface. This work aims to explore efficient transfer of heat in Eyring-Powell nanofluid with bio-convection. Nanofluids possess significant features that have aroused various investigators because of their utilization in industrial and nanotechnology. The influence of including motile microorganism is to stabilize the nanoparticle suspensions develop by the mixed influence of magnetic field and buoyancy force. This research paper reveals the detailed information about the linearly compressed Magnetohydrodynamics boundary layer flux of two dimensional Eyring-Powell nanofluid through disposed surface area due to the existence of microorganism with inclusion the influence of non- linear thermal radiation, energy activation and bio-convection. The liquid is likely to allow conduction and thickness of the liquid is supposed to show variation exponentially. By using appropriate similarity type transforms, the nonlinear PDE's are converted into dimensionless ODE's. The results of ODE's are finally concluded by employing (HAM) Homotopy Analysis approach. The influence of relevant parameters on concentration, temperature, velocity and motile microorganism density are studied by the use of graphs and tables. We acquire skin friction, local Nusselt and motil microorganism number for various parameters.

• Journal of Yeungnam Medical Science
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• 제9권2호
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• pp.269-274
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• 1992

본 연구에서는 1992년 3월부터 8월까지 유방 병소로 본원에 내원하여 유방암으로 확진된 12명을 대상으로 초음파 소견을 분석하여 다음과 같은 결론을 얻었다. 즉 종괴경계의 불규칙적인 분엽성(12/12), 종괴 내부의 저 echo(11/12), 종괴음영의 비균질성(11/12), 후방음영의 감소(7/12), 변연 echo의 증강(9/12), 표재층의 분열(11/12), 종괴의 전후경에 대한 횡경의 비율(T/AP<1.4 : 9/12), 소석회화(2/12), 피부의 비후(2/12) 등의 소견들이 유방암을 감별 진단하는데 도움을 주지만, 이들 소견들은 반드시 유방암에서만 관찰되는 소견들은 아니고, 유방암외의 다른 양성병변들에서도 그 빈도는 낮지만 관찰될 수 있는 소견들로서, 유방 초음파검사상의 이들 소견만으로 유방암을 정확히 감별진단하기는 힘들며, 보다 정확한 진단을 위해서는 X-선 유방촬영법같은 다른 영상진단법과의 상호보완을 통한 종합적인 검사가 필요할 것이다.