• Title/Summary/Keyword: size series

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Standardized Uptake Values Highly Correlate with Tumor Size and Fuhrman Grade in Patients with Clear Cell Renal Cell Carcinoma

  • Polat, Emre Can;Otunctemur, Alper;Ozbek, Emin;Besiroglu, Huseyin;Dursun, Murat;Ozer, Kutan;Horsanali, Mustafa Ozan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7821-7824
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    • 2014
  • Background: We investigated the correlation between standardized uptake value (SUVmax), tumor size and Fuhrman grade in patients with renal cell carcinoma (RC). Materials and Methods: We retrospectively analyzed the data of 54 patients with clear cell renal cell carcinoma histopathologically diagnosed who underwent fluorine-18 fluoro-2 deoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) between January 2005 and March 2014. Results: Avarage tumor sizes were $5.64{\pm}1.85$, $6.85{\pm}2.24$ and $7.98{\pm}2.45$ in low, medium and high SUVmax groups, respectively. The Spearman's correlation coefficient between the tumor size and SUVmax was 0.385 (p=0.004) and between the Fuhrman grade and SUVmax was 0.578 (p<0.001). Conclusions: SUVmax appears highly correlated with tumor size and Fuhrman grade in patients with histopathologically confirmed clear cell RC. Multicenter studies are needed to provide larger series for more accurate results.

Size effect on tensile strength of filament wound CFRP composites (필라멘트 와인딩 탄소섬유 복합재의 인장강도 크기 효과)

  • Hwang, T.K.;Doh, Y.D.;Kim, H.G.
    • Composites Research
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    • v.24 no.5
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    • pp.1-8
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    • 2011
  • This paper presents the results of theoretical analysis and experimental test to show the size effect on the fiber strength of filament would pressure vessel. First, a series of fully scaled hoop ring tests with filament would carbon-epoxy were conducted, which exhibited a remarkable size effect on the fiber strength. Next, the failure analyses using WWLM(Weibull Weakest Link Model) and the SMFM(Sequential Multi-step Failure Model) were performed and compared to the hoop ring test data, as well as to unidirectional specimens test data from the literature. It was found that the analysis results significantly underestimated the fiber strengths compared to the test data. In this study, a modified SMFM was proposed through the modification of the length size effect. The fiber strengths from modified SMFM analysis showed good agreement with the test data.

Study on the Influence of Mixing Effect to the Measurement of Particle Size Distribution using DMA and CPC (혼합효과가 DMA와 CPC를 이용한 입자분포 측정에 미치는 영향에 관한 연구)

  • Lee, Youn-Soo;Ahn, Kang-Ho;Kim, Sang-Soo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.27 no.3
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    • pp.326-333
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    • 2003
  • In the measurement using DMA and CPC in series, there is some time delay for particles classified in DMA to detect in CPC. During this time, the DMA time-response changes due to the velocity profile of sampling tube and the diffusion of particles in the volume that exists between the DMA exit and the detector of ultra-fine CPC. This is called mixing effect. In the accelerated measurement methods like the TSI -SMPS, the size distribution is obtained from the correlation between the time-varying electrical potential of the DMA and the corresponding particle concentrations sampled in DMA. If the DMA time -response changes during this delay time, this can cause the error of a size distribution measured by this accelerated technique. The kernel function considering this mixing effect using the residence time distribution is proposed by Russell et al. In this study, we obtained a size distribution using this kernel to compare to the result obtained by the commercial accelerated measurement system, TSI -SMPS for verification and considered the errors that result from the mixing effect with the geometric mean diameters of originally sampled particles, using virtually calculated responses obtained with this kernel as input data.

Estimation of Permeability Coefficient Using Fractal Dimension of Particle Size Distribution Curve in Granular Soils (조립토 입도분포곡선의 프랙탈차원을 이용한 투수계수의 예측)

  • Park Jae-Seong;Chang Pyoung-Wuck;Son Young-Hwan;Kim Seong-Pil
    • Journal of The Korean Society of Agricultural Engineers
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    • v.48 no.4
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    • pp.41-49
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    • 2006
  • Since particle size distribution curves are useful to estimate permeability of soil, many formulae for permeability coefficient (k) have been published using the parameter from the curves and factors, such as grain size, particle shape and void ratio of soils. However, the parameters such as $C_c,\;C_u$ and $D_n$ derived from only some discrete points on the curve are insufficient to represent the whole gradation. In this paper fractal dimension which is quite new concept and known to be able to represent the entire curve of particle size distribution is employed for the parameters. An empirical formula of permeability coefficient has been developed with fractal dimension and percent of finer than 0.075 mm. The formula developed from this study has confirmed its effectiveness by a series of laboratory tests and comparison to other published formulae. It is found that permeability coefficient is proportional to fractal dimension and inversely proportional to percent of fines.

Amorphous Ultrafine Particle Preparation for Improvement of Bioabailability of Insolube Drugs: Effect of Co-Grinding of UDCA with SLS (난용성 의약품의 생체이용률 증진을 위한 무정형 초미립자의 조제 : UDCA와 SLS의 혼합분쇄 효과)

  • 정한영;곽성신;김현일;최우식
    • YAKHAK HOEJI
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    • v.46 no.2
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    • pp.102-107
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    • 2002
  • The particle size of medicinal materials is an important physical property which affects the pharmaceutical behaviors such as dissolution, chemical stability, compressibility and bioavailability of solid dosage forms. The size reduction of raw pharmaceutical powder is needed to formulize insoluble drugs or slightly soluble drugs and to improve the pharmaceutical properties such as the solubility, the pharmaceutical mixing and the dispersion. The objective of the present study is to evaluate the grinding characteristics of ursodeoxycholic acid(UDCA) as a model of insoluble drugs. The effects of the grinding time and the amount of additive on particle size distribution of ground UDCA were investigated. Grinding of insoluble drug, UDCA and a series of dry co-grinding experiments of UDCA with sodium lauryl sulfate(SLS) as an additive were carried out using a planetary ball mill. It was measured that the median diameter and the particle size distribution of ground products with grinding UDCA and additive SLS by Mastersizer. As a result of co-grinding of UDCA and SLS, the particle size of co-grinding products was decreased more than single grinding one. However, it was observed that co-grinding products were reaggregated to larger particles after 120 min.

Study of the Valence and Rydberg States of a Lithium Dimer by the Multi-reference Configuration-interaction Method

  • Lee, Chun-Woo
    • Bulletin of the Korean Chemical Society
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    • v.35 no.5
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    • pp.1422-1432
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    • 2014
  • Convergent all-electron multi-reference configuration-interaction (MRCI) calculations are performed for a lithium dimer with Kaufmann's Rydberg basis functions. A comparison of the results of these calculations with those of the effective core potential/core polarization potential (ECP/CPP) method and experimental data reveals the deficiency of the all-electron ab initio method. The deficiency is related to the mere 51.9% attainment of electron correlation for the ground state. The percent attainment of electron correlation for the first excited state is slightly better than that for the ground state, preventing us from obtaining better agreements with experimental data by means of increasing the size of basis sets. The Kaufmann basis functions are then used with the ECP/CPP method to obtain the accurate convergent potential energy curves for the $^1\prod_u$ states correlated to Li(2p) + Li(2p) and Li(2s) + Li(n = 2, 3, 4). Quantum defect curves (QDCs) calculated for both the $X^2\sum_g$ and 1 $^2\prod_u$ states of the $Li{_2}^+$ ion and the Lu-Fano plot reveal a strong series-series interaction between the two $2snp{\pi}$ and $2pnp{\pi}$ Rydberg series. The QDCs are then used to resolve assignment problems in the literature. The reassignments, performed by Jedrzejewski-Szemek et al., of the dissociation product of the D $^1\prod$ state from (2s+3d) to (2s+3p) and that of the 6 $^1\prod_u$ from (2s+4d) to (2s+4p) are found to be incorrect. It may be more natural to assign their $2snp{\pi}$ Rydberg series as a $2snd{\pi}$ series. The state, assigned as 5p $^1\prod_u$ by Ross et al. and 4d $^1\prod$ by Jedrzejewski-Szemek et al., is assigned as the 7 $^1\prod_u$ state, correlated to the Li(2s) + Li(4f) limit.

Exploiting Patterns for Handling Incomplete Coevolving EEG Time Series

  • Thi, Ngoc Anh Nguyen;Yang, Hyung-Jeong;Kim, Sun-Hee
    • International Journal of Contents
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    • v.9 no.4
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    • pp.1-10
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    • 2013
  • The electroencephalogram (EEG) time series is a measure of electrical activity received from multiple electrodes placed on the scalp of a human brain. It provides a direct measurement for characterizing the dynamic aspects of brain activities. These EEG signals are formed from a series of spatial and temporal data with multiple dimensions. Missing data could occur due to fault electrodes. These missing data can cause distortion, repudiation, and further, reduce the effectiveness of analyzing algorithms. Current methodologies for EEG analysis require a complete set of EEG data matrix as input. Therefore, an accurate and reliable imputation approach for missing values is necessary to avoid incomplete data sets for analyses and further improve the usage of performance techniques. This research proposes a new method to automatically recover random consecutive missing data from real world EEG data based on Linear Dynamical System. The proposed method aims to capture the optimal patterns based on two main characteristics in the coevolving EEG time series: namely, (i) dynamics via discovering temporal evolving behaviors, and (ii) correlations by identifying the relationships between multiple brain signals. From these exploits, the proposed method successfully identifies a few hidden variables and discovers their dynamics to impute missing values. The proposed method offers a robust and scalable approach with linear computation time over the size of sequences. A comparative study has been performed to assess the effectiveness of the proposed method against interpolation and missing values via Singular Value Decomposition (MSVD). The experimental simulations demonstrate that the proposed method provides better reconstruction performance up to 49% and 67% improvements over MSVD and interpolation approaches, respectively.

Evaluation of Agricultural Drought Prevention Ability Based on EOF Analysis and Multi-variate Time Series Model (EOF 해석 및 다변량시계열 모형을 이용한 농업가뭄 대비능력의 평가)

  • Yoo Chul-Sang;Kim Dae-Ha;Kim Sang-Dan
    • Journal of Korea Water Resources Association
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    • v.39 no.7 s.168
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    • pp.617-626
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    • 2006
  • In this study 3-month SPI data from 59 stations over the Korean peninsula are analyzed by deriving and spatially characterizing the EOFs. Also, the coefficient time series of EOF are applied to the multi-variate time series model to generate the time series of 10,000 years, to average them to estimate the areal average, and to decide the maximum drought severity for given return periods. Finally, the drought prevention ability is evaluated by considering the effective storage of dam within the basin and the size of agricultural area. Especially for the return period of 30 years, only the Han river basin has the potential to overcome the drought. Other river basins like the Youngsan river basin, which has a large portion of agricultural area but less water storage, are found to be very vulnerable to the rainfall-sensitive agricultural drought.

The Bonding Strength Characteristic of the Filler Metal Powder on the TLP Bonded Region of Superalloy GTD-111DS (일방향 초내열합금 GTD-111DS에서 삽입금속 분말에 따른 천이액상확산접합부의 접합강도 특성)

  • Oh, In-Seok;Kim, Gil-Moo;Moon, Byeong-Shik
    • Journal of Welding and Joining
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    • v.25 no.5
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    • pp.45-50
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    • 2007
  • The Ni-base superalloy GTD111 DS is used in the first stage blade of high power land-based gas turbines. Advanced repair technologies of the blade have been introduced to the gas turbine industry over recent years. The effect of the filler metal powder on Transient Liquid Phase bonding phenomenon and tensile mechanical properties was investigated on the GTD111 DS superalloy. At the filler metal powder N series, the base metal powders fully melted at the initial time and a large amount of the base metal near the bonded interlayer was dissolved by liquid inter metal. Liquid filler metal powder was eliminated by isothermal solidification which was controlled by the diffusion of B into the base metal. The solids in the bonded interlayer grew from the base metal near the bonded interlayer inward the insert metal during the isothermal solidification. The bond strength of N series filler metal powder was over 1000 MPa. and ${\gamma}'$ phase size of N series TLP bonded region was similar with base metal by influence of Ti, Al elements. At the insert metal powder M series, the Si element fluidity of the filler metal was good but microstructure irregularity on bonded region because of excessive Si element. Nuclear of solids formed not only from the base metal near the bonded interlayer but also from the remained filler metal powder in the bonded interlayer. When the isothermal solidification was finished, the content of the elements in the boned interlayer was approximately equal to that of the base metal. But boride and silicide formed in the base metal near the bonded interlayer. And these boride decreased with the increasing of holding time. The bond strength of M series filler metal powder was about 400 MPa.

Discontinuity in GNSS Coordinate Time Series due to Equipment Replacement

  • Sohn, Dong-Hyo;Choi, Byung-Kyu;Kim, Hyunho;Yoon, Hasu;Park, Sul Gee;Park, Sang-Hyun
    • Journal of Positioning, Navigation, and Timing
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    • v.11 no.4
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    • pp.287-295
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    • 2022
  • The GNSS coordinate time series is used as important data for geophysical analysis such as terrestrial reference frame establishment, crustal deformation, Earth orientation parameter estimation, etc. However, various factors may cause discontinuity in the coordinate time series, which may lead to errors in the interpretation. In this paper, we describe the discontinuity in the coordinate time series due to the equipment replacement for domestic GNSS stations and discuss the change in movement magnitude and velocity vector difference in each direction before and after discontinuity correction. To do this, we used three years (2017-2019) of data from 40 GNSS stations. The average magnitude of the velocity vector in the north-south, east-west, and vertical directions before correction is -12.9±1.5, 28.0±1.9, and 4.2±7.6 mm/yr, respectively. After correction, the average moving speed in each direction was -13.0±1.0, 28.2±0.8, and 0.7±2.1 mm/yr, respectively. The average magnitudes of the horizontal GNSS velocity vectors before and after discontinuous correction was similar, but the deviation in movement size of stations decreased after correction. After equipment replacement, the change in the vertical movement occurred more than the horizontal movement variation. Moreover, the change in the magnitude of movement in each direction may also cause a change in the velocity vector, which may lead to errors in geophysical analysis.