• Journal of Information Technology Applications and Management
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• 제25권4호
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• pp.157-169
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• 2018

The purpose of this study was to examine the volatility of bitcoin, diagnose if bitcoin are a systematic risk asset, and evaluate their effectiveness by estimating market beta representing systematic risk using GARCH (Generalized Auto Regressive Conditional Heteroskedastieity) model. First, the empirical results showed that the market beta of Bitcoin using the OLS model was estimated at 0.7745. Second, using GARCH (1, 2) model, the market beta of Bitcoin was estimated to be significant, and the effects of ARCH and GARCH were found to be significant over time, resulting in conditional volatility. Third, the estimated market beta of the GARCH (1, 2), AR (1)-GARCH (1), and MA (1)-GARCH (1, 2) models were also less than 1 at 0.8819, 0.8835, and 0.8775 respectively, showing that there is no systematic risk. Finally, in terms of efficiency, GARCH model was more efficient because the standard error of a market beta was less than that of the OLS model. Among the GARCH models, the MA (1)-GARCH (1, 2) model considering non-simultaneous transactions was estimated to be the most appropriate model.

• 한국식생활문화학회지
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• 제21권1호
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• pp.51-56
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• 2006

This research suggests critical and specific decisive variables that affect general service quality of the products in family restaurants, considering features of services in which consumption and production happens simultaneous by collecting the raw data through point of sales. It also analyses the factors and helps to offer them practical strategies by providing managers of the restaurants and marketers with empirical viewpoints based on the research. Generally, family restaurants need their own physical environment and are required to encourage customers to revisit themselves by maintaining pleasant environment as well as, considering space for customers and for employees' working routes and effective maintenance of the facilities. The result of the study also tells that even if the unimportant factors did not affect much on the restaurants, management over these factors can be a differentiated strategy for competitive advantage over the other businesses.

• 한국전기전자재료학회논문지
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• 제37권1호
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• pp.11-25
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• 2024

Lithium-ion batteries (LIBs) have attracted great attention as the common power source in energy storage fields of large-scale applications such as electrical vehicles (EVs), industries, power plants, and grid-scale energy storage systems (ESSs). Insertion, alloying, and conversion reactions are the main electrochemical energy storage mechanisms in LIBs, which determine their electrochemical properties and performances. The electrochemical reaction mechanisms are determined by several factors including crystal structure, components, and composition of electrode materials. This article reviews a new strategy to compensate for the intrinsic shortcomings of each reaction mechanism by introducing the material systems to form a single compound with different types of reaction mechanisms and to allow the simultaneous hybrid electrochemical reaction of two different mechanisms in a single solid solution phase.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2503-2508
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• 2013

Histone deacetylation mediated by histone deacetylases (HDACs) has been reported as one of the epigenetic mechanisms associated with tumorigenesis. The poor responsiveness of anticancer drugs found with cholangiocarcinoma (CCA) leads to short survival rate. We aimed to investigate mRNA expression of HDACs class I and II, and the effect of HDAC inhibitors, suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA), in CCA in vitro. Expression of HDACs was studied in CCA cell lines (M213, M214 and KKU-100) and an immortal cholangiocyte (MMNK1) by semi-quantitative reverse transcription-PCR. SAHA and VPA, as well as a classical chemotherapeutic drug 5 -fluorouacil (5-FU) were used in this study. Cell proliferation was determined by sulforhodamine assay. $IC_{50}$ and $IC_{20}$ were then analyzed for each agent and cell line. Moreover, synergistic potentional of VPA or SAHA in combination with 5-FU at sub toxic does ($IC_{20}$) of each agent was also evaluated. Statistic difference of HDACs expression or cell proliferation in each experimental condition was analyzed by Student's t-test. The result demonstrated that HDACs were expressed in all studied cell types. Both SAHA and VPA inhibited cell proliferation in a dose-dependent manner. Interestingly, KKU-100 which was less senstitive to classical chemotheraoeutic 5-FU was highly was sensitive to HDAC inhibitors. Simultaneous combination of subtoxic doses of HDAC inhibitors and 5-FU signiicantly inhibited cell proliferation in CCA cell lines compared to single sgent treatment($P{\leq}0.01$), while sequentially combined treatments were less effective. The present study showed inhibitory effects of HDACIs on cell proliferation in CCA cell lines, with synergistic antitumor potential demonstrated by simultaneous combination of VPA or SAHA with 5-FU, suggesting a novel alternative therapeutic strategy in effective treatment of CCA.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권6호
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• pp.3012-3028
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• 2017

In this paper, we propose a joint power control strategy for both the uplink and downlink transmission by considering the energy requirements of the user equipments' uplink data transmissions in data and energy integrated communication networks (DEINs). In DEINs, the base station (BS) adopts the power splitting (PS) aided simultaneous wireless information and power transfer (SWIPT) technique in the downlink (DL) transmissions, while the user equipments (UEs) carry out their own uplink (UL) transmissions by exploiting the energy harvested during the BS's DL transmissions. In our DEIN model, there are M UEs served by the BS in order to fulfil both of their DL and UL transmissions. The orthogonal frequency division multiple access (OFDMA) technique is adopted for supporting the simultaneous transmissions of multiple UEs. Furthermore, a transmission frame is divided into N time slots in the medium access control (MAC) layer. The mathematical model is established for maximizing the sum-throughput of the UEs' DL transmissions and for ensuring their fairness during a single transmission frame T, respectively. In order to achieve these goals, in each transmission frame T, we optimally allocate the BS's power for each subcarrier and the PS factor for each UE during a specific time slot. The original optimisation problems are transformed into convex forms, which can be perfectly solved by convex optimisation theories. Our numerical results compare the optimal results by conceiving the objective of maximising the sum-throughput and those by conceiving the objective of maximising the fair-throughput. Furthermore, our numerical results also reveal the inherent tradeoff between the DL and the UL transmissions.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제41회 하계 정기 학술대회 초록집
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• pp.208-209
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• 2011

In this work, we developed self-assembled monolayers (SAMs) of alkanethiols on gold that can release amine groups, when an electrical potential was applied to the gold. The strategy was based on the introduction of the electroactive carbamate group, which underwent the two-electron oxidation with simultaneous release of the amine molecules, to alkanethiols. The synthesis of the designed thiol compounds was achieved by coupling isocyanate-containing compound with hydroquinone. The electroactive thiols were mixed with hydroxyl-containing alkanethiol [$HS(CH_2)_{11}OH$] to form mixed monolayers, and cyclic votammetry was used for the characterization of the release. The mixed SAMs showed a first oxidation peak at +540 mV (versus Ag/AgCl reference electrode), demonstrating irreversible conversion from carbamate to hydroqinone with simultaneous release of the amine groups. The second and third cycles showed typical reversible redox reaction of hydroquinone and quione: the oxidation and reduction occurred at +290 mV and -110 mV, respectively. The measurement of ToF-SIMS further indicates that electrochemical-assisted chemical reaction successfully released amine groups. This new SAM-based electrochemistry would be applicable for direct release of biologically active molecules that contain amine groups.

• 한국과 국제사회
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• 제2권1호
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• pp.69-92
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• 2018

북한은 2006년 1차 핵실험을 시작으로 2017년 9월까지 총 6차례의 핵실험을 감행하였다. 북한은 미국의 대북적대시 정책에 대응하기 위한 일환으로 체제수호와 방어적 차원에서 핵무장력 담보 전략을 전개하고 있다. 그러나 북한 핵실험의 전략적 목표가 북미협상을 통해 북한체제 위기를 극복하고 그들의 한반도 사회주의통일을 위한 핵무장력을 완성하는 데 있음은 주지의 사실이다. 북한의 계속된 핵실험은 한반도평화를 위협하는 직접적인 요인이 되고 있으며, 동북아안보 역학구도에 간접적인 요인으로 작용하고 있다. 유엔안보리는 이러한 북한의 무모한 핵실험에 대해 지난 10년 이상 6차례의 유엔안보리 결의로 대북제재조치를 단행해 왔다. 그러나 북한 김정은 정권은 유엔과 미국 등 국제사회의 대북제재 조치에도 불구하고 핵 경제병진노선을 고수하겠다는 입장이다. 유엔과 미국의 대북제재조치가 북한에 대한 효과적인 영향을 주지 못한 것은 북한이 강도높은 핵실험으로 격상시키는데 요인으로 분석된다. 2017년 미국의 트럼프 행정부가 대북제재 조치 수단 가운데 하나인 대북 군사옵션은 한반도에서의 전면전과 국지전 양상으로 예상된다. 미 트럼프 행정부는 이전의 미국 행정부의 대북제재 조치 양상과는 다르게 세컨더리 보이콧이라는 외교압박전술을 시도하고 있다. 그럼에도 불구하고 북한은 유엔과 미국의 대북제재조치에 대해 북 미 간 전면적인 군사대결 입장을 밝히며 '벼랑끝 전술'로 맞서고 있다. 북한은 당분간 체제생존차원에서 핵 경제병진노선을 추진할 것으로 판단된다. 북한체제는 미 중 간의 현실주의적 국가전략 추진으로 체제붕괴 변수가 나타날 수 있다는 점에서 북한의 전략적 선택의 폭은 좁아진다.

• Journal of Ginseng Research
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• 제35권1호
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• pp.31-38
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• 2011

In order to distinguish the cultivation area of Panax ginseng, principal component analysis (PCA) using quantitative and qualitative data acquired from HPLC was carried out. A new HPLC method coupled with evaporative light scattering detection (HPLC-ELSD) was developed for the simultaneous quantification of ten major ginsenosides, namely $Rh_1$, $Rg_2$, $Rg_3$, $Rg_1$, Rf, Re, Rd, $Rb_2$, Rc, and $Rb_1$ in the root of P. ginseng C. A. Meyer. Simultaneous separations of these ten ginsenosides were achieved on a carbohydrate analytical column. The mobile phase consisted of acetonitrile-water-isopropanol, and acetonitrile-water-isopropanol using a gradient elution. Distinct differences in qualitative and quantitative characteristics for ginsenosides were found between the ginseng roots produced in two different Korean cultivation areas, Ganghwa and Punggi. The ginsenoside profiles obtained via HPLC analysis were subjected to PCA. PCA score plots using two principal components (PCs) showed good separation for the ginseng roots cultivated in Ganghwa and Punggi. PC1 influenced the separation, capturing 43.6% of the variance, while PC2 affected differentiation, explaining 18.0% of the variance. The highest contribution components were ginsenoside $Rg_3$ for PC1 and ginsenoside Rf for PC2. Particularly, the PCA score plot for the small ginseng roots of six-year old, each of which was light than 147 g fresh weight, showed more distinct discrimination. PC1 influenced the separation between different sample sets, capturing 51.8% of the variance, while PC2 affected differentiation, also explaining 28.0% of the variance. The highest contribution component was ginsenoside Rf for PC1 and ginsenoside $Rg_2$ for PC2. In conclusion, the HPLC-ELSD method using a carbohydrate column allowed for the simultaneous quantification of ten major ginsenosides, and PCA analysis of the ginsenoside peaks shown on the HPLC chromatogram would be a very acceptable strategy for discrimination of the cultivation area of ginseng roots.

• 기술혁신학회지
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• 제18권1호
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• pp.49-72
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• 2015

2011년에 촉발되어 전 세계 20여 건에 이르는 Apple과 Samsung의 특허분쟁은 경쟁적 기술전략의 첨예한 양상을 보여준 대표적 사례이다. 두 기업 간 특허소송은 스마트폰 시장에서의 치열한 경쟁구조를 잘 보여준다. 반면, 두 기업은 ICT 및 하이테크 시장 선두기업으로서의 서로 긴밀한 협력적 관계에 있다. 그러나 기존 연구들은 경쟁 또는 협력의 한 부분만을 고려한 나머지 실제 기술경영의 현상을 제대로 진단하지 못했을 뿐 아니라 어떠한 패턴을 보이면서 진화하는지 규명하지 못하였다. 이에 본 연구는 경쟁-협력 동시적 공존의 코피티션(Coopetition) 산업생태계를, Apple과 Samsung의 스마트폰 분쟁사례를 중심으로 분석하고 그 함의와 방향성을 도출하고자 한다. 경쟁관점에서는 두 기업 간 소송자료 및 일지를 활용하여 분쟁의 흐름을, 협력관점에서는 소송에서 쟁점이 된 특허들의 인용정보를 활용하여 핵심기술을 구성하는 지식의 경향과 이전방향을 네트워크 분석방법론을 통해 분석한다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.1387-1391
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• 2003

The fundamental aim of this paper is to present a solution algorithm to achieve cooperative contour controlling, under joint acceleration constraint with maximum cooperative speed. Usually, the specifications like maximum velocity of cooperative trajectory are determined by the application itself. In resolving the cooperative trajectory into two complementary trajectories, an optimum task resolving strategy is employed so that the task assignment for each robot is fair under the joint acceleration constraint. The proposed algorithm of being an off-line technique, this could be effectively and conveniently extended to the existing servo control systems irrespective of the computational power of the controller implemented. Further, neither a change in hardware setup nor considerable reconfiguration of the existing system is required in adopting this technique. A simulation study has been carried out to verify that the proposed method can be realized in the generation of complementary trajectories so that they could meet the stipulated constraints in simultaneous maneuvering.