• Journal of Korean Academy of Nursing
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• v.27 no.1
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• pp.26-35
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• 1997

This study was done to examine knowledge about, and need for sex education among university students in Korea. This study design was descriptive survey design. The data were collected from 540 university students from June 10 to June 30, 1996, using questionnaires developed by the authors. The results are as follows : Those who had sex education had higher scores in sex knowledge than those had not had sex education. The average score for sex knowledge was 71.9 of a maximum score of 100. Knowledge of sexually transmitted disease was scored highest of 79.8, and knowledge of the anatomy and physiology of the reproductive system was scored lowest at 60.9. The subjects who answered 'yes' about the necessity of sex education numbered 529(98%) and the most important reason given for needing sex education was to cope well with physical and psychological developments. Regarding the content of sex education, a choice of relevant contraceptive methods was given the highest rating. Anatomy and physiology of reproductive system was the least choser subject as the first priority among five topics. Yet, sex education for university students should include anatomy and physiology of the reproductive system, considering the low level of knowledge on this topic in the subjects of this study and its importance as a part of sex education.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.3953-3958
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• 2016

Prostatic cancer is the second cause of cancer-related death among men worldwide. The human papilloma viruses (HPVs) are a family of sexually transmitted viruses which have may have roles in the ethiology of inflammation in prostate leading to benign prostatic hyperplasia (BPH) and prostate cancer (PCa). In this study, we evaluated the frequency of different HPV types in prostatic cancer and benign prostatic hyperplasia (BPH) in Kerman province, southeast of Iran, using real-time PCR techniques. The aim of the present research was to clarify any association with prostatic carcinogenesis. Real Time PCR showed that HPV DNA was found in 20% of 200 PCa samples, 80 percent of these with high-risk HPV types, 40% with type-16,18, 30 % type-31,33 and 10% type 54. High risk HPV DNA was detected in only 2% of BPH samples. Values for low risk types were much higher. Our study provided a support for the role of high risk HPV infection in prostatic disease in Iranian patients, and association between presence of HPV DNA and prostate carcinoma. In particular, HPV 16 and18 might have an important role in prostate cancer.

• Korean Journal of Health Education and Promotion
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• v.20 no.2
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• pp.149-162
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• 2003

The purpose of this study was to investigate of the sexual behavior, attitude and knowledge of delinquence adolescents. Data were collected by self-report from 224 delinquence adolescents of the juvenile protection and education organizations in Gwangju city from June 18 to 21, 2002 in Korea. The results were as follows； The concern of subjects on sexual education was pregnancy, delivery and miscarriage(17.4%), date with boy-girl mends(13.9%) and sexually transmitted disease/AIDS(13.1%). The experiences of sexual behavior was masturbation(86.5%), sexual intercourse(79.6%), sexual desire(70.0%) and pregnancy(27.6%). There were statistically significant differences between age and contraception(p＜0.05), age and pregnancy(p＜0.05). The average score for sex attitude was 38.32. The average score for sex knowledge was 7.65. There were statistically significant correlation between sex attitude and sexual intercourse(p＜0.01), sex knowledge and intercourse(p＜0.05), sex knowledge and contraception(p＜0.05), sex attitude and pregnancy (p＜0.05), sex knowledge and sexual desire(p＜0.05). In conclusion, juvenile delinquence adolescents should be educated on sexuality continuously to express there sexual behavior patterns with the right morality and knowledge in any sexual arousal situation.

• Journal of Korea Association of Health Promotion
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• v.2 no.2
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• pp.215-230
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• 2004

Along with a development of medical technology, a variety of tests, such as laboratory tests, x-ray and endoscopies are being used in health screening tests. As the tests determine the quality of health screening, test items and methods should be carefully selected. This study was to get hold of the test items of major health screening programs in Korea. Most of the health screening programmes focused upon detection of risk factors and diagnosis of life-style related diseases(diabetes, hypertension, cardiovascular diseases, hypercholesterolemia, overweight, drinking, smoking, cerebrovascular diseases, osteoporosis) ,cancers(stomach, cervix, lung, breast, liver, colon, prostate, ovary, pancreas, thyroid, esophagus), infectious diseases (hepatitis, tuberculosis, sexually-transmitted diseases, parasites),chronic obstructive respiratory diseases, chronic renal diseases(bacteriuria, hematuria, proteinuria), anemia, glaucoma, hearing loss, Alzheimer disease, stress, early Psychiatric diseases. The health screening tests were basic physical examination, basic laboratory tests(CBC, urinalysis, liver function tests, lipid tests, glucose, HbAlc, uric acid, electrolytes, serological tests(HBsAg, HBs-Ab, HCV-Ab, HIV-Ab, VDRL) EKG, x-ray(chest PA, CT), endoscopy (gastroscopy, colonoscopy) , sonography(abdormen, thyroid, pelvis, breast) , cytology(cervix) ,bone density, tumor markers(NMP22, alpha-FP, CEA, CA-19-9, CA12S, PSA) and eye tests. Advanced technologies, like CT, PET, MIRI, MIRI/Angio, molecular testings) were widely usedin hospital health screening programmes. In summary, a variety of were utilized by stages or programmes, however a few subjects. tests were utilized in health screening in Korea. Those tests according to sex and age in most of health screening program used tests to excess disregarding health screening subject.

• The Journal of Korean Society for School & Community Health Education
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• v.15 no.1
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• pp.1-13
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• 2014

Objectives: The purpose of this study was to provide substantial foundation to establish effective sex education plan for university students, and to inquire into sexual knowledge, consciousness and values of university students and into whether there are difference between health related major subjects and non-health related major subjects. Methods: This study was conducted on students in 227 health related major subjects and 226 non-health related major subjects in chungbuk C city. The Questionnaire, used in this study, was re-made on basis of reviews and previous studies, and total of 453 questionnaires were used. Results: Sexual knowledge scores were not significantly difference between health related major subjects and non-health related major subjects. but health related major subjects were more educated contraception, pregnancy artificial abortion, sexually transmitted disease than non-health related major subjects. Sexual knowledge was correlated with attitude in sex, times of sex education and usefulness of sex education. Conclusion: The university authorities make a curriculum for systematic sex educations and need to assertive support students and they can have right sexual consciousness and have mature and responsible attitude to sex through right education of knowledge in sex.

• Parasites, Hosts and Diseases
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• v.54 no.1
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• pp.75-80
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• 2016

This study explored epidemiological trends in trichomoniasis in Daegu, South Korea. Wet mount microscopy, PCR, and multiplex PCR were used to test for Trichomonas vaginalis in vaginal swab samples obtained from 621 women visiting 2 clinics in Daegu. Of the 621 women tested, microscopy detected T. vaginalis in 4 (0.6%) patients, PCR detected T. vaginalis in 19 (3.0%) patients, and multiplex PCR detected T. vaginalis in 12 (1.9%) patients. Testing via PCR demonstrated high sensitivity and high negative predictive value for T. vaginalis. Among the 19 women who tested positive for T. vaginalis according to PCR, 94.7% (18/19) reported vaginal signs and symptoms. Notably, more than 50% of T. vaginalis infections occurred in females younger than 30 years old, and 58% were unmarried. Multiplex PCR, which simultaneously detects pathogens from various sexually transmitted infections, revealed that 91.7% (11/12) of patients were infected with 2 or more pathogens. Mycoplasma hominis was the most prevalent co-infection pathogen with T. vaginalis, followed by Ureaplasma urealyticum and Chlamydia trachomatis. Our results indicate that PCR and multiplex PCR are the most sensitive tools for T. vaginalis diagnosis, rather than microscopy which has been routinely used to detect T. vaginalis infections in South Korea. Therefore, clinicians should take note of the high prevalence of T. vaginalis infections among adolescent and young women in order to prevent persistent infection and transmission of this disease.

• Journal of Korean Academy of Nursing
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• v.27 no.2
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• pp.423-432
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• 1997

This is a descriptive study to understand the preventive stage for STDs to provide a basis for sex education for college students. The colleges were selected by quota sampling in five representative cities in Korea. but the 1,691 college students were selected by convenient sampling in the cities nationwide, and the data were collected by self-reporting using a questionnaire consisting of 33 items. The results were as follows : 1. Their mean ages were 21.8 for female and 23.3 for male students, 2.78.0% of the males md 46.5% of the females permitted premarital sex, 57.1% of male and 10.3% of female college students had experienced sexual intercourse, 7. l% of males and 2.4% of females had experienced pregnancy, 10.3% of males and 3.4% of females had been infected with STDs, 72.1% of male and 13.8% of female didn't use condoms at the time of infection. 3. Most of the factors related to STDs infection, such as drinking, smoking, frequency of sexual intercourse. pregnancy, knowledge of STDs, the score of STDs prevention were statistically higher in the male student group than in the female group. 4. The students' mean score of knowledge about STDs was similar between the male group(7.80) and the female group(7.84) with a possible score range from 0-18. 5. Only fifteen percent of male and 9.6% of female students expressed that they will do something to prevent STD. 6. The group having the experience of sexual intercourse(t=3.924, P=.048) and the group of having experience of contracting STDs(t=16.638, P=.000) had shown statistically higher STDs prevention score than the group not having that kind of experience. but the group having experience with pregnancy didn't show any difference from. the group not having experience with pregnancy. Considering that 57.1% of males and 10.3% of females had sexual intercourse experience, 78% of male and 46.5% of female permitted premarital sex, 10.3% of male and 3.4% of female had been infected with STDs. It could be concluded that the college students were ignorant about the prevention of STDs and had unrealistic stage of the STDs prevention. Therefore, enforcement of education for the prevention of STDs including the dynamics of the sexual intercourse and STDs infection is needed.

• Parasites, Hosts and Diseases
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• v.54 no.3
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• pp.329-334
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• 2016

Trichomoniasis caused by Trichomonas vaginalis is a common sexually transmitted disease. Its association with several health problems, including preterm birth, pelvic inflammatory disease, cervical cancer, and transmission of human immunodeficiency virus, emphasizes the importance of improved access to early and accurate detection of T. vaginalis. In this study, a rapid and efficient loop-mediated isothermal amplification-based method for the detection of T. vaginalis was developed and validated, using vaginal swab specimens from subjects suspected to have trichomoniasis. The LAMP assay targeting the actin gene was highly sensitive with detection limits of 1 trichomonad and 1 pg of T. vaginalis DNA per reaction, and specifically amplified the target gene only from T. vaginalis. Validation of this assay showed that it had the highest sensitivity and better agreement with PCR (used as the gold standard) compared to microscopy and multiplex PCR. This study showed that the LAMP assay, targeting the actin gene, could be used to diagnose early infections of T. vaginalis. Thus, we have provided an alternative molecular diagnostic tool and a point-of-care test that may help to prevent trichomoniasis transmission and associated complications.

• Biomedical Science Letters
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• v.11 no.1
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• pp.15-22
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• 2005

Trichomoniasis is a sexually transmitted disease induced by Trichomonas vaginalis, a parasitic protozoan. The symptoms of trichomoniasis are rarely appeared that the infections are distributed worldwide from underdeveloped to developed countries. The diagnosis of trichomoniasis is mainly taken by wet smear following microscopic examination, of which the diagnostic accuracies are poor and varies with the clinicians' experiences. Therefore, more exact and convenient diagnostic methods for T. vaginalis are required. Here, we cloned and expressed recombinant T. vaginalis adhesion protein 33 (rTvAP33) using an E. coli expression system. rTvAP33 was then immunized to rabbit and BALB/c mice for the production of anti-rTvAP33 antibodies. Sandwich ELISA using these antibodies detected T. vaginalis cultured in TYM broth supplemented with ferrous ions. Vagina-parasitizing microorganisms showed low cross-reactivities in this system. These results suggest that Tv AP33 is a good diagnostic target for the detection of TvAP33-expressing T. vaginalis.

• BMB Reports
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• v.48 no.2
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• pp.103-108
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• 2015

Trichomoniasis caused by the parasitic protozoan Trichomonas vaginalis is the most common sexually transmitted disease in the world. Dendritic cells are antigen presenting cells that initiate immune responses by directing the activation and differentiation of naive T cells. In this study, we analyzed the effect of Trichomonas vaginalis-derived Secretory Products on the differentiation and function of dendritic cells. Differentiation of bone marrow-derived dendritic cells in the presence of T. vaginalis-derived Secretory Products resulted in inhibition of lipopolysaccharide-induced maturation of dendritic cells, down-regulation of IL-12, and up-regulation of IL-10. The protein components of T. vaginalis-derived Secretory Products were shown to be responsible for altered function of bone marrow-derived dendritic cells. Chromatin immunoprecipitation assay demonstrated that IL-12 expression was regulated at the chromatin level in T. vaginalis-derived Secretory Products-treated dendritic cells. Our results demonstrated that T. vaginalis- derived Secretory Products modulate the maturation and cytokine production of dendritic cells leading to immune tolerance.