• Journal of Yeungnam Medical Science
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• 제37권3호
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• pp.242-245
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• 2020

Pregnancy-related ocular diseases develop mostly in the third trimester of pregnancy. Here, we describe a case of a pregnant woman with a choroidal mass that caused a serous retinal detachment during the first trimester of pregnancy. The patient's condition resolved spontaneously after an abortion.

• Journal of Yeungnam Medical Science
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• 제34권1호
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• pp.111-114
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• 2017

Central serous chorioretinopathy may induce poor eyesight and serous retinal detachment. However, its exact cause has not been well established thus far. It can be associated with systemic high-dose corticosteroid treatment mainly for young and middle-aged men and may spontaneously regress or recur after withdrawal from corticosteroid. After corticosteroid administration for Behcet's disease, it is necessary to identify any ocular symptoms. Behcet's disease can lead to the development of ocular complications, such as uveitis, hypopyon, retinal vasculitis, optic neuritis, angiogenesis, secondary cataract, and glaucoma. It is possible to diagnose any of these complications via optical coherence tomography and digital indocyanine green angiography. It is easy to neglect an ocular symptom that may appear after a low-dose corticosteroid treatment as an ocular complication in patients with Behcet's disease. Thus, we report on a case concerning high-dose corticosteroid treatment with a literature review.

• Applied Microscopy
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• 제37권2호
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• pp.103-109
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• 2007

뒤쥐 Sorex caecutiens의 악하선의 미세구조를 연구하였다. 악하선은 샘포들과 도관들로 구성되었다. 악하선 샘포는 잘 발달된 조면소포체, 미토콘드리아와 많은 전자밀도가 있는 분비과립으로 채워진 장액선 세포와 점액선 세포를 가지는 혼합샘이었다. 장액선 샘포 과립은 명확한 한계막이 없는 타원형으로 다양한 전자밀도를 가지는 거친 알갱이만을 가지고 있었다. 점액선 샘포 과립은 명확한 한계막이 없는 타원형이고 전자밀도가 있는 균질한 기질 내에 몇 개의 연하거나 투명한 띠를 가져 다양한 문양으로 관찰되었다. 따라서 뒤쥐아과(Soricinae)에 속하는 뒤쥐, S. caecutiens의 악하선 샘포 과립은 샘포 과립의 경계막의 부재와 점액 샘포 과립의 특별한 문양으로 땃쥐아과(Crocidurinae)를 포함한 다른 포유류 종들과 구분된다. 과립관세포에서 많은 작은 과립소포와 층으로 된 한계막으로 덮이고 거친 장액성의 분비 과립 혹은 균질한 기질로 채워진 몇 개의 특징적 구조들이 관찰되었다.

• 대한세포병리학회지
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• 제17권2호
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• pp.108-115
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• 2006

Evaluation of serous effusions can include immunocytochemical stains that differentiate reactive mesothelial cell from adenocarcinoma cell. Among several positive mesothelial cell markers, we used desmin, CK5/6, WT1 and calretinin all known to have high sensitivity and specificity as selective mesothelial cell markers. We studied smears obtained with cytospin from 15 malignant and eight benign effusions. The mesothelial cells were positively stained by desmin, CK5/6, WT1 and calretinin in 60.9%, 29.1%, 26.7% and 56.5%, respectively among 8 benign and 15 malignant effusions; the adenocarcinoma cells were positively stained 6.7%, 13.3%, 1.0% and 0.0%, respectively among 15 malignant effusions. The percentage of positively stained mesothelial cells were somewhat lower for all antibodies compared to the results of previous studies. This was likely due to the differences in preparation methods and fixatives among studies. In conclusion, the use of desmin and calretinin were more valuable than CK5/6 and WT1 for distinguishing between reactive mesothelial cell and adenocarcinoma cells in serous effusion; however, choice of the proper preparation methods and fixatives are also important

• Journal of Medicine and Life Science
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• 제20권1호
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• pp.48-52
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• 2023

High-grade serous carcinoma (HGSC) is the most common type of pelvic cancer among women. Serous tubal intraepithelial carcinoma (STIC) is a precursor lesion of HGSC. Herein, we report a rare occurrence of STIC in patients undergoing surgery for benign indications without a family history of ovarian cancer. A 77-year-old woman underwent total laparoscopic hysterectomy and bilateral salpingo-oophorectomy for uterine prolapse. Pathological examination revealed bilateral STIC without ovarian abnormalities, and no other abnormal findings were noted. Another patient, a 49-year-old woman, underwent laparoscopic total hysterectomy and bilateral salpingectomy for uterine fibroids. STIC lesions were observed in both fallopian tubes. Subsequently, a staging was performed. No additional lesions were found, and the patient was followedup through imaging and blood tests. As reports of STIC lesions are rare, data on their clinical outcomes and management strategies are limited. In this report, we present cases of incidental STIC in benign surgery and discuss its proper interpretation and management. Through the early detection of STIC lesions, patients with risk factors can be identified in advance, which will allow prevention and early detection of ovarian cancer. Opportunistic salpingectomy was also actively discussed in this regard.

• 대한영상의학회지
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• 제81권2호
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• pp.418-422
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• 2020

췌장의 장액성 낭성 종양은 일반적으로 양성 질환으로 알려져 있으나 드물게 악성화를 보이는 사례들이 보고되고 있다. 영운에서 췌장 미부에 발생한 장액성 낭성 종양을 수술로 제거한 후 추적 관찰 중 국소 재발과 함께 간으로의 원격전이가 발생한 증례를 경험하여 보고하고자 한다.

• Applied Microscopy
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• 제35권4호
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• pp.91-97
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• 2005

이하선의 선세포와 분비과립을 작은땃쥐 Crocidura suaveolens와 우수리땃쥐 C. lasiura에서 연구하였다. 두 종 모두의 이하선은 장액선세포 한 종류만을 가지는 장액선이었고 선세포, 사이관, 과립관 그리고 줄무늬관들은 평범하였다. 작은땃쥐의 경우, 장액선세포는 잘 발달된 조면소포체, 현저한 골지체, 몇몇의 큰 미토콘드리아와 성숙 혹은 융합하고 있는 많은 중간 정도의 전자 밀도 과립들을 가지고 있었다. 미성숙 선세포의 분비과립들은 미세하고 강한 전자 밀도의 알갱이만으로 혹은 알갱이들이 주가 되었고 불분명한 경계막을 가지고 있었고, 성숙 분비과립들은 균일하고 옅은 중심부를 가지고 그 주변에 미세하고 강한 전자밀도의 알갱이들과 명확한 경계막을 가지고 있었다. 우수리땃쥐의 경우, 선세포는 잘 발달된 조면소포체, 현저한 골지체, 몇몇의 큰 미토콘드리아 뿐 아니라 성숙 혹은 융합하고 있는 많은 진한 전자 밀도의 분비과립들을 가지고 있었다. 미성숙 선세포 분비과립들은 옅고 거친 알갱이들만으로 채워져 있었으며 불명확한 경계막을 가지고 있었고, 성숙 분비과립들은 진하고 거친 알갱이들만으로 채워져 있었고 명확한 경계막을 가지고 있었다. 결국, 작은땃쥐의 이하선 분비과립은 광학과 전자현미경 수준에서 중간 정도의 전자밀도로, 우수리땃쥐의 분비과립은 광학 현미경 수준에서는 아주 진하게, 전자현미경에서는 진하게 관찰되었다.

• Korean Journal of Radiology
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• 제25권6호
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• pp.559-564
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• 2024

Incidental pancreatic cystic lesions are a common challenge encountered by diagnostic radiologists. Specifically, given the prevalence of benign pancreatic cystic lesions, determining when to recommend aggressive actions such as surgical resection or endoscopic ultrasound with sampling is difficult. In this article, we review the common types of cystic pancreatic lesions including serous cystadenoma, intraductal papillary mucinous neoplasm, and mucinous cystic neoplasm with imaging examples of each. We also discuss high-risk or worrisome imaging features that warrant a referral to a surgeon or endoscopist and provid several examples of these features. These imaging features adhere to the latest guidelines from the International Consensus Guidelines, American Gastroenterological Association (2015), American College of Gastroenterology (2018), American College of Radiology (2010, 2017), and European Guidelines (2013, 2018). Our focused article addresses the imaging dilemma of managing incidental cystic pancreatic lesions, weighing the options between imaging follow-up and aggressive interventions.

• 대한세포병리학회:학술대회논문집
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• 대한세포병리학회 2008년도 제22차 춘계학술대회
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• pp.11-11
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• 2008

• 치과방사선
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• 제21권2호
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• pp.183-197
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• 1991

After single fraction of 2, 5, 10 Gy irradiation on submandibular gland of 40 male rats, weighing 150gm, respectively, these animal were sacrificed two hours after 0.1㎎/g bromodeoxyuridine (Sigma) peritoneal injection in 1, 3, 7, 15 hours, 1, 3, 7 days after irradiation. And excised submandibular gland were fixed in Carnoy's and Bouin's solution for 2 hours. Paraffin sections were stained with H&E, and PAS for the observation of the change of salivary gland tissue, and with Feulgen for the study of the DNA distribution, and immunohistochemically stained with anti-bromodeoxyuridine (Sanbyo Co.) for detection of DNA synthetic cells in order to study the distribution of DNA synthetic cells of salivary gland tissue and endothelium after irradiation in 5 different sites of 6 slides on X 200 high power field. The results were as followings. 1. In PAS staining 3 days after 5Gy irradiation, decreased mucine secretion of serous cells were found, and 7 days after l0Gy irradiation, decreased mucine secretion of mucous cells were found. 2. In histopathologic features, degeneration of serous cells were found in 3 days after 2 Gy irradiation and there was little change in mucous cells and excretory duct cells. 3. In Feugen staining, 3 days after 2 Gy, 5 Gy irradiation, more high percentage of DNA synthetic cells were found in intercalated duct cells, striated duct cells and excretory duct cells than in BrdU staining. 4. In immunohistochemical features, DNA synethsis of serous cells and granular convoluted tubular cells abruptly decreased in early period after irradiation and showed no recovery in 7 days after irradiation but there was an increase in DNA synthesis of intercalated duct cells, striated duct cells and excretory duct cells, which have less S-phase cells comparatively, in 7 days after 2 Gy, 5 Gy irradiation. 5. In immunohistochemical features, the DNA synthesis of endothelial cells was continuously decreased after irradiation but showed slight increase in 7 days after 2 Gy and S Gy irradiation.