DOI QR코드

DOI QR Code

Malignant Pancreatic Serous Cystic Neoplasm: A Case of Local Recurrence and Liver Metastasis that Occurred During Follow-Up

췌장의 악성 장액성 낭성 종양: 추적 관찰 중 국소 재발과 함께 간 전이를 보인 증례 보고

  • Jin Hee Park (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kyung A Kang (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kyung Seek Chang (Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Heon Ju Kwon (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Mi Sung Kim (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
  • 박진희 (성균관대학교 의과대학 강북삼성병원 영상의학과) ;
  • 강경아 (성균관대학교 의과대학 강북삼성병원 영상의학과) ;
  • 장경식 (성균관대학교 의과대학 강북삼성병원 병리과) ;
  • 권헌주 (성균관대학교 의과대학 강북삼성병원 영상의학과) ;
  • 김미성 (성균관대학교 의과대학 강북삼성병원 영상의학과)
  • Received : 2019.03.01
  • Accepted : 2019.07.01
  • Published : 2020.03.01

Abstract

Serous cystic neoplasms of the pancreas are usually benign, with a low malignant potential. Herein, we report a case of malignant serous cystic neoplasm of the pancreas treated with subtotal pancreatectomy, which progressed to local recurrence and metachronous hepatic metastasis during the regular follow-up period.

췌장의 장액성 낭성 종양은 일반적으로 양성 질환으로 알려져 있으나 드물게 악성화를 보이는 사례들이 보고되고 있다. 영운에서 췌장 미부에 발생한 장액성 낭성 종양을 수술로 제거한 후 추적 관찰 중 국소 재발과 함께 간으로의 원격전이가 발생한 증례를 경험하여 보고하고자 한다.

Keywords

References

  1. Campbell F, Azadeh B. Cystic neoplasms of the exocrine pancreas. Histopathology 2008;52:539-551 https://doi.org/10.1111/j.1365-2559.2007.02856.x
  2. George DH, Murphy F, Michalski R, Ulmer BG. Serous cystadenocarcinoma of the pancreas: a new entity? Am J Surg Pathol 1989;13:61-66 https://doi.org/10.1097/00000478-198901000-00009
  3. Huh J, Byun JH, Hong SM, Kim KW, Kim JH, Lee SS, et al. Malignant pancreatic serous cystic neoplasms: systematic review with a new case. BMC Gastroenterol 2016;16:97
  4. Friebe V, Keck T, Mattern D, Schmitt-Graeff A, Werner M, Mikami Y, et al. Serous cystadenocarcinoma of the pancreas: management of a rare entity. Pancreas 2005;31:182-187 https://doi.org/10.1097/01.mpa.0000167001.89018.3c
  5. Jais B, Rebours V, Malleo G, Salvia R, Fontana M, Maggino L, et al. Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas). Gut 2016;65:305-312 https://doi.org/10.1136/gutjnl-2015-309638
  6. Robinson SM, Scott J, Oppong KW, White SA. What to do for the incidental pancreatic cystic lesion? Surg Oncol 2014;23:117-125 https://doi.org/10.1016/j.suronc.2014.04.001
  7. Bano S, Upreti L, Puri SK, Chaudhary V, Sakuja P. Imaging of pancreatic serous cystadenocarcinoma. Jpn J Radiol 2011;29:730-734 https://doi.org/10.1007/s11604-011-0617-3
  8. Formentini A, Birk D, Siech M, Mattfeldt T, Fortnagel G, Beger HG. Serous cystadenocarcinoma of the pancreas and serous cystadenoma associated with ductal pancreatic adenocarcinoma. HPB 2000;2:41-48 https://doi.org/10.1016/S1365-182X(17)30700-1
  9. Bramis K, Petrou A, Papalambros A, Manzelli A, Mantonakis E, Brennan N, et al. Serous cystadenocarcinoma of the pancreas: report of a case and management reflections. World J Surg Oncol 2012;10:51
  10. Van Dyke TJ, Johlin FC, Bellizzi AM, Howe JR. Serous cystadenocarcinoma of the pancreas: clinical features and management of a rare tumor. Dig Surg 2016;33:240-248 https://doi.org/10.1159/000444721