• Title/Summary/Keyword: sensitivity to damage

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Vulnerability Assessment of Soil Loss in Farm area to Climate Change Adaption (기후변화 적응 농경지 토양유실 취약성 평가)

  • Oh, Young-Ju;Kim, Myung-Hyun;Na, Young-Eun;Hong, Sun-Hee;Paik, Woen-Ki;Yoon, Seong-Tak
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.5
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    • pp.711-716
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    • 2012
  • Due to the climate change in South Korea the annual total precipitation will increase by 17 percent by 2100. Rainfall is concentrated during the summer in South Korea and the landslide of farmland by heavy rain is expected to increase. Because regional torrential rains accompanied by a storm continue to cause the damage in farmland urgent establishment of adaptation plant for minimizing the damage is in need. In this study we assessed vulnerability of landslide of farmland by heavy rain for local governments. Temporal resolution is 2000 year and the future 2020 year, 2050 year, 2100 year via A1B scenario. Vulnerability of local government were evaluated by three indices such as climate exposure, sensitivity, adaptive capacity and each index is calculated by selected alternative variable. Collected data was normalized and then multiplied by weight value that was elicited in delphi investigation. Current vulnerability is concentrated in Jeju island and Gyeongsangnam-do, however, it is postulated that Kangwon-do will be vulnerable in the future. Through this study, local governments can use the data to establish adaptation plans for farmland landslide by climate change.

Development of a Probabilistic Safety Assessment Framework for an Interim Dry Storage Facility Subjected to an Aircraft Crash Using Best-Estimate Structural Analysis

  • Almomani, Belal;Jang, Dongchan;Lee, Sanghoon;Kang, Hyun Gook
    • Nuclear Engineering and Technology
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    • v.49 no.2
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    • pp.411-425
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    • 2017
  • Using a probabilistic safety assessment, a risk evaluation framework for an aircraft crash into an interim spent fuel storage facility is presented. Damage evaluation of a detailed generic cask model in a simplified building structure under an aircraft impact is discussed through a numerical structural analysis and an analytical fragility assessment. Sequences of the impact scenario are shown in a developed event tree, with uncertainties considered in the impact analysis and failure probabilities calculated. To evaluate the influence of parameters relevant to design safety, risks are estimated for three specification levels of cask and storage facility structures. The proposed assessment procedure includes the determination of the loading parameters, reference impact scenario, structural response analyses of facility walls, cask containment, and fuel assemblies, and a radiological consequence analysis with dose-risk estimation. The risk results for the proposed scenario in this study are expected to be small relative to those of design basis accidents for best-estimated conservative values. The importance of this framework is seen in its flexibility to evaluate the capability of the facility to withstand an aircraft impact and in its ability to anticipate potential realistic risks; the framework also provides insight into epistemic uncertainty in the available data and into the sensitivity of the design parameters for future research.

Modeling and optimization of infill material properties of post-installed steel anchor bolt embedded in concrete subjected to impact loading

  • Saleem, Muhammad
    • Smart Structures and Systems
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    • v.29 no.3
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    • pp.445-455
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    • 2022
  • Steel anchor bolts are installed in concrete using a variety of methods. One of the most common methods of anchor bolt installation is using epoxy resin as an infill material injected into the drilled hole to act as a bonding material between the steel bolt and the surrounding concrete. Typical design standards assume uniform stress distribution along the length of the anchor bolt accompanied with single crack leading to pull-out failure. Experimental evidence has shown that the steel anchor bolts fail owing to the multiple failure patterns, hence these design assumptions are not realistic. In this regard, the presented research work details the analytical model that takes into consideration multiple micro cracks in the infill material induced via impact loading. The impact loading from the Schmidt hammer is used to evaluate the bond condition bond condition of anchor bolt and the epoxy material. The added advantage of the presented analytical model is that it is able to take into account the various type of end conditions of the anchor bolts such as bent or U-shaped anchors. Through sensitivity analysis the optimum stiffness and shear strength properties of the epoxy infill material is achieved, which have shown to achieve lower displacement coupled with reduced damage to the surrounding concrete. The accuracy of the presented model is confirmed by comparing the simulated deformational responses with the experimental evidence. From the comparison it was found that the model was successful in simulating the experimental results. The proposed model can be adopted by professionals interested in predicting and controlling the deformational response of anchor bolts.

Induction of Micronuclei in Human and Mouse Lymphocytes Irradiated with Gamma Radiation and Effect of Panax ginseng C.A. Meyer (마우스와 사람 림프구에서 방사선에 의한 미소핵의 형성 및 고려인삼의 효과)

  • Kim, Sung-Ho;Oh, Heon;Lee, Song-Eun;Lee, Yun-Sil;Kim, Tae-Hwan;Jeong, Kyu-Sik;Ryu, Si-Yun
    • Journal of Radiation Protection and Research
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    • v.22 no.3
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    • pp.153-160
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    • 1997
  • The frequencies of ${\gamma}$-ray-induced micronuclei (MN) in cytokinesis-blocked (CB) lymphocytes at several doses were measured in three donors of human and C57BL/6 mice. Measurements performed after irradiation showed a dose-related increases in MN frequency in each of the donors studied. The relative sensitivity of mouse in spleen lymphocytes (SLs) compared with human peripheral blood lymphocytes (PBLs) was estimated by best fitting linear-quadratic model based on the radiation-induced MN data over the range from 0 cGy to 400 cGy. In the case of MN frequency with 0.2 per CB cell, the relative sensitivity of mouse SLs was 1.67. Compared with the radiation-induced MN formation in the PBLs of human, the SLs of mouse were more radiosensitive. Using this MN assay with human PBLs and mouse SLs, studies were performed to determine whether the water fraction of ginseng (Panax ginseng C.A.Meyer) against radiation-induced MN in human PBLs after in vitro irradiation (3Gy) and in SLs of C57BL/6 mice after in vivo irradiation (3Gy). The frequency of MN in human PBLs was reduced by water fraction of ginseng (0.5mg/ml of medium) both pre-and post treatment (p<0.0l) in vitro. In addition, the frequency of MN in mouse SLs was also reduced by pretreatment of ginseng (2mg/ml of drinking water for 7days) in vivo. The data suggested that the ginseng may reduce cell damage caused by ${\gamma}$-rays in vitro and in vivo. Further studies are needed to characterize better the protective nature of ginseng extract, its fractions and compounds.

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Phenotypic Suppression of Rad53 Mutation by CYC8 (CYC8에 의한 rad53 돌연변이의 표현형 억제에 대한 연구)

  • Park, Kyoung-Jun;Choi, Do-Hee;Kwon, Sung-Hun;Kim, Joon-Ho;Bae, Sung-Ho
    • Korean Journal of Microbiology
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    • v.46 no.2
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    • pp.122-126
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    • 2010
  • RAD53 functions as an effector kinase of checkpoint pathways in Saccharomyces cerevisiae, which plays a central role to regulate many downstream cellular processes in response to DNA damage. It also involves in transcriptional activation of various genes including RNR genes which encode the key enzyme required for dNTP synthesis. In this study, we identified CYC8 as a suppressor for the hydroxyurea sensitivity of $rad53{\Delta}$ mutation. $Rad53{\Delta}$ mutant transformed with a multi-copy plasmid containing CYC8 showed increased hydroxyurea resistance. In contrast, TUP1 which forms a complex with CYC8 did not function as a suppressor. In the case of mutations, both $cyc8{\Delta}$ and $tup1{\Delta}$ suppressed hydroxyurea sensitivity of $rad53{\Delta}$. Since CYC8 can propagate as a prion in yeast, overexpression of CYC8 induced misfolding of the normal CYC8 proteins, resulting in dominant cyc8-phenotype. Therefore, it is suggested that CYC8 can act as a multi-copy suppressor due to its prion property. It was observed that the levels of RNR transcription were increased in the yeast strains containing either multi-copies of CYC8 gene or $cyc8{\Delta}$ mutation, suggesting that the increased level of RNR will elevate the intracellular pools of dNTPs, which, in turn, suppress the phenotype of $rad53{\Delta}$ mutation.

The effect of methyl yellow concentrations on the optical properties of polyvinyl chloride-methyl yellow film as a radiation dosimeter

  • Muhamad Yasin Yunus;Farah Nurlidar;Santoso Soekirno;Rizka Fitriana;Marrisa Arlinkha Ega Putri;Arif Rachmanto;Adam Tirta Kusuma
    • Nuclear Engineering and Technology
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    • v.56 no.10
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    • pp.4097-4102
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    • 2024
  • A dosimetry system's ability to monitor absorbed doses is crucial for the quality assurance and control of products that have been exposed to radiation. Here, we propose a polyvinyl chloride (PVC)-methyl yellow (MY) film as a potential dosimeter for irradiation facilities. The PVC-MY film was prepared with a simple solvent-casting method at different MY concentrations from 0.3 to 1.2 mM. To evaluate the dosimeter's performance, the film was exposed to gamma-irradiation with irradiation doses of 0-25 kGy. The optical characteristics of the films examined using a UV-Vis spectrophotometer showed that the color of the films changed from yellow to red with increasing irradiation doses, and the color change sensitivity of the films increased with increasing MY concentrations. The absorption spectra of the irradiated PVC-MY films showed three maximum absorption peaks at 417, 522, and 547 nm. As irradiation doses increased, the film absorption at 417 nm decreased, while the film absorption at 522 and 547 nm increased. The film's stability studies suggest storage of the irradiated film in a cold-dark conditions is recommended to prevent damage and maintain response stability. The findings in this study emphasize the potential of the PVC-MY film as a dosimeter for irradiation facilities.

Structural Analysis of Deepwater Steel Catenary Riser using OrcaFlex (OrcaFlex를 이용한 심해 SCR 구조 해석)

  • Park, Kyu-Sik;Choi, Han-Suk;Kim, Do-Kyun;Yu, Su-Young;Kang, Soo-Chang
    • Journal of Ocean Engineering and Technology
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    • v.29 no.1
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    • pp.16-27
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    • 2015
  • The design challenges when attempting to obtain sufficient strength for a deepwater steel catenary riser (SCR) include high stress near the hang-off location, an elevated beam-column buckling load due to the effective compression in the touchdown zone (TDZ), and increased stress and low-cycle fatigue damage in the TDZ. Therefore, a systematic strength analysis is required for the proper design of an SCR. However, deepwater SCR analysis is a new research area. Thus, the objective of this study was to develop an overall analysis procedure for a deepwater SCR. The structural behavior of a deepwater SCR under various environmental loading conditions was investigated, and a sensitivity analysis was conducted with respect to various parameters such as the SCR weight, weight of the internal contents, hang-off angle (HOA), and vertical soil stiffness. Based on a deepwater SCR design example, it was found that the maximum stress of an SCR occurred at a hang-off location under parallel loading direction with respect to the riser plane, except for a wave dominant dynamic survival loading condition. Furthermore, the tensile stress governed the total stress of the SCRs, whereas the bending stress governed the total stress at the TDZ. The weight of the SCR and internal contents affected the maximum stress of the SCR more than the HOA and vertical soil stiffness, because the weight of the SCR, including the internal contents, was directly related to its tensile stress.

Techniques for Evaluation of Ecological and Aesthetic Aspects of Landscapes through GIS Overlay Method (생태경관다양성과 시각경관민감도를 적용한 GIS중첩평가 계획기법)

  • Jang, Rai-Ik;Lee, Myung-Woo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.37 no.4
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    • pp.22-31
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    • 2009
  • In this study a landscape evaluation was carried out for the submission of a natural landscape conservation plan with the intention to prevent damage to natural landscapes through incautious exploitation. In the case of Korean landscape evaluation, in fact, only the aesthetic value of the landscape is evaluated as related to development projects but the ecological relevance of the landscape cannot be estimated by evaluating only the aesthetic. For that reason, this study performed a landscape evaluation, including the sensitivity limit of visible scenery and the diversity of ecological scenery. For the intention of landscape evaluation in the designation of an essential conservation area and for devising a plan related to this area, a GIS applied to Ian McHarg's map overlay method was used and both the ecological landscape diversity and the aesthetic value of the landscape was surveyed using this map overlay method. A region can be analyzed in relation to the needs for concentration of management in influence analysis of landscape effect elements.

RADIATION DAMAGE IN THE HUMAN BODY ACUTE RADIATION SYNDROME AND MULTIPLE ORGAN FAILURE

  • AKASHI, MAKOTO;TAMURA, TAIJI;TOMINAGA, TAKAKO;ABE, KENICHI;HACHIYA, MISAO;NAKAYAMA, FUMIAKI
    • Nuclear Engineering and Technology
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    • v.38 no.3
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    • pp.231-238
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    • 2006
  • Whole-body exposure to high-dose radiation causes injury involving multiple organs that depends on their sensitivity to radiation. This acute radiation syndrome (ARS) is caused by a brief exposure of a major part of the body to radiation at a relatively high dose rate. ARS is characterized by an initial prodromal stage, a latent symptom-free period, a critical or manifestation phase that usually takes one of four forms (three forms): hematologic, gastrointestinal, or cardiovascular and neurological (neurovascular), depending upon the exposure dose, and a recovery phase or death. One of the most important factors in treating victims exposed to radiation is the estimation of the exposure dose. When high-dose exposure is considered, initial dose estimation must be performed in order to make strategy decisions for treatment as soon as possible. Dose estimation can be based on onset and severity of prodromal symptoms, decline in absolute lymphocyte count post exposure, and chromosomal analysis of peripheral blood lymphocytes. Moreover, dose assessment on the basis of calculation from reconstruction of the radiation event may be required. Experience of a criticality accident occurring in 1999 at Tokai-mura, Japan, showed that ARS led to multiple organ failure (MOF). This article will review ARS and discuss the possible mechanisms of MOF developing from ARS.

Differential Responses of Three Cyanobacteria to UV-B and Cd

  • Atri, Neelam;Rai, Lal-Chand
    • Journal of Microbiology and Biotechnology
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    • v.13 no.4
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    • pp.544-551
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    • 2003
  • Interactive effects of UV-B and Cd on growth, pigment, photosynthesis, and lipid peroxidation have been studied in Anabaena, Microcystis, and Nostoc; all the tested cyanobacteria showed differential sensitivity to different dosage of UV-B and Cd alone as well as in combination. Phycocyanin was severely affected by UV-B and Cd by all the strains; the degree of pigment bleaching was most pronounced in Anabaena followed by Microcystis and Nostoc. $UV-B_2+Cd_2$ produced nearly 83, 78, and 65% inhibition of phycocyanin in Anabaena, Microcystis, and Nostoc, respectively. The above treatment also significantly decreased the contents of Chl ${\alpha}$ and carotenoid. Presence of capsule in Microcystis protected the phycocyanin bleaching as compared to decapsulated cells. Laboratory-grown Microcystis revealed about 75 and 80% inhibition, following $UV-B_2+Cd_2$ treatment, respectively. in capsulated and decapsulated cells. Damage caused by Cd was more pronounced than UV-B. Inhibition of photosynthesis did occur in all the test strains, being maximum in Anabaena. PS II was the most sensitive component of the electron transport chain, showing 84, 80, and 70% inhibition in Anabaena, Microcystis, and Nostoc, respectively. As compared to control, significant lipid peroxidation (6.5-fold higher) was observed in Anabaena with $UV-B_2+Cd_2$, $^{14}C-uptake$ was more susceptible to Cd and Uv-B than oxygen-evolution. Approximately 84, 80, and 76% inhibition of $^{14}C-uptake$ was observed in Anabaena, Microcystis, and Nostoc, respectively. Similarly, $UV-B_2+Cd_2$ inhibited APT content of Anabaena by 87%. This ,study suggests that inhibition of carbon fixation was due to decreased ATP content of the test cyanobacteria by UV-B+Cd, where Anabaena was the most sensitive and Nostoc the most tolerant.