• Title/Summary/Keyword: sensitivity increasing method

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Effect of irradiation on the Porphyromonas gingivalis (방사선조사가 Porphyromonas gingivalis에 미치는 영향)

  • Lee, Chang-Hwan;Kim, Gyu-Tae;Choi, Yong-Suk;Hwang, Eui-Hwan
    • Imaging Science in Dentistry
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    • v.38 no.1
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    • pp.39-47
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    • 2008
  • Purpose: The aim of this study was to observe a direct effect of irradiation on the periodontopathic Porphyromonas gingivalis (P. gingivalis). Materials and Methods: P. gingivalis 2561 was exposed to irradiation with a single absorbed dose of 10, 20, 30, and 40Gy. Changes in viability and antibiotic sensitivity, morphology, transcription, and protein profile of the bacterium after irradiation were examined by pour plating method, disc diffusion method, transmission electron microscopy, RT-PCR, and immunoblot, respectively. Results: Viability of irradiated P. gingivalis drastically reduced as irradiation dose was increased. Irradiated P. gingivalis was found to have become more sensitive to antibiotics as radiation dose was increased. With observation under the transmission electron microscope, the number of morphologically abnormal cells was increased with increasing of irradiation dose. In RT-PCR, decrease in the expression of fimA and sod was observed in irradiated P. gingivalis. In immunoblot, change of profile in irradiated P. gingivalis was found in a number of proteins including 43-kDa fimbrillin. Conclusion: These results suggest that irradiation may affect the cell integrity of P. gingivalis, which is manifested by the change in cell morphology and antibiotic sensitivity, affecting viability of the bacterium.

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Influencing Factors on Sensitivity of Pressure Decay Test for Membrane Damage Assessment (막 손상 측정을 위한 압력손실시험의 감도에 영향을 미치는 인자)

  • Lee, Yong-Soo;Kim, Hyung-Soo;Kim, Jong-Oh
    • Membrane Journal
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    • v.27 no.4
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    • pp.367-373
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    • 2017
  • Pressurized membrane module systems, including hollow fiber type of Microfiltration (MF) and Ultrafiltration (UF) membranes are being increasingly used in drinking water treatment due to their high removal efficiency of pathogen. However, when fibers are damaged in pressurized membrane system, the pathogen will be able to penetrate the membrane. Therefore, it is essential to guarantee the regulatory requirements for water quality by an effective on-line or off-line condition integrity monitoring methods. Recently, pressure decay test (PDT) which is one of membrane integrity tests has been reflected to drinking water treatment plants using pressurized membrane module. In this paper, three different method were used to perform PDT and three different sensitivity values were analyzed through experiments. Three types of direct integrity test methods were applied to pressure feed side, filtrate side and bidirectional pressure decay test. The results of these experiments show that the sensitivity was increasing when the volume of pressurized gas was decreasing. The sensitivity is inversely proportional to the gas volume. Furthermore, it is desirable to increase pressure difference between feed side and permeate side in order to achieve higher sensitivity in the PDT by membrane damage.

Modified Principal Component Analysis for Real-Time Endpoint Detection of SiO2 Etching Using RF Plasma Impedance Monitoring

  • Jang, Hae-Gyu;Kim, Dae-Gyeong;Chae, Hui-Yeop
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.32-32
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    • 2011
  • Plasma etching is used in microelectronic processing for patterning of micro- and nano-scale devices. Commonly, optical emission spectroscopy (OES) is widely used for real-time endpoint detection for plasma etching. However, if the viewport for optical-emission monitoring becomes blurred by polymer film due to prolonged use of the etching system, optical-emission monitoring becomes impossible. In addition, when the exposed area ratio on the wafer is small, changes in the optical emission are so slight that it is almost impossible to detect the endpoint of etching. For this reason, as a simple method of detecting variations in plasma without contamination of the reaction chamber at low cost, a method of measuring plasma impedance is being examined. The object in this research is to investigate the suitability of using plasma impedance monitoring (PIM) with statistical approach for real-time endpoint detection of $SiO_2$ etching. The endpoint was determined by impedance signal variation from I-V monitor (VI probe). However, the signal variation at the endpoint is too weak to determine endpoint when $SiO_2$ film on Si wafer is etched by fluorocarbon plasma on inductive coupled plasma (ICP) etcher. Therefore, modified principal component analysis (mPCA) is applied to them for increasing sensitivity. For verifying this method, detected endpoint from impedance analysis is compared with optical emission spectroscopy (OES). From impedance data, we tried to analyze physical properties of plasma, and real-time endpoint detection can be achieved.

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The Design of Rear Suspension Using Hydroforming (하이드로포밍을 이용한 후륜 현가장치 설계)

  • Oh, J.H.;Choi, H.H.;Lee, G.M.;Park, S.H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2008.05a
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    • pp.205-208
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    • 2008
  • Generally, there are several types in rear suspension. The rear suspension of subframe type consisting of side member and front/rear cross member is widely used in a medium car and full car. In the small car case, the beam of tubular type without independent suspension system is used to reduce manufacturing cost. The optimized rear suspension of subframe type using hydroforming method has been developed in this study. In designing suspension, the driving stability and durability performance should be considered as an important factor. The stability is related to dynamic frequency and durability is connected with stress analysis of structure. We focus on increasing the stiffness of suspension and decreasing the maximum stress relating to durability cycle life. For making use of the merits of hydroforming which is possible to make the bead, tube expansion, and feeding in desiring position, several optimization design techniques such as shape, size, and topology optimization are proposed. This optimization scheme based on the sensitivity can provide distinguished performance improvement in using hydroforming. Through commercial software based on the finite element, the superiority of this design method is demonstrated.

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Classification of Fall Direction Before Impact Using Machine Learning Based on IMU Raw Signals (IMU 원신호 기반의 기계학습을 통한 충격전 낙상방향 분류)

  • Lee, Hyeon Bin;Lee, Chang June;Lee, Jung Keun
    • Journal of Sensor Science and Technology
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    • v.31 no.2
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    • pp.96-101
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    • 2022
  • As the elderly population gradually increases, the risk of fatal fall accidents among the elderly is increasing. One way to cope with a fall accident is to determine the fall direction before impact using a wearable inertial measurement unit (IMU). In this context, a previous study proposed a method of classifying fall directions using a support vector machine with sensor velocity, acceleration, and tilt angle as input parameters. However, in this method, the IMU signals are processed through several processes, including a Kalman filter and the integration of acceleration, which involves a large amount of computation and error factors. Therefore, this paper proposes a machine learning-based method that classifies the fall direction before impact using IMU raw signals rather than processed data. In this study, we investigated the effects of the following two factors on the classification performance: (1) the usage of processed/raw signals and (2) the selection of machine learning techniques. First, as a result of comparing the processed/raw signals, the difference in sensitivities between the two methods was within 5%, indicating an equivalent level of classification performance. Second, as a result of comparing six machine learning techniques, K-nearest neighbor and naive Bayes exhibited excellent performance with a sensitivity of 86.0% and 84.1%, respectively.

Coordination among the Security Systems using the Blackboard Architecture (블랙보드구조를 활용한 보안 모델의 연동)

  • 서희석;조대호
    • Journal of Institute of Control, Robotics and Systems
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    • v.9 no.4
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    • pp.310-319
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    • 2003
  • As the importance and the need for network security are increased, many organizations use the various security systems. They enable to construct the consistent integrated security environment by sharing the network vulnerable information among IDS (Intrusion Detection System), firewall and vulnerable scanner. The multiple IDSes coordinate by sharing attacker's information for the effective detection of the intrusion is the effective method for improving the intrusion detection performance. The system which uses BBA (Blackboard Architecture) for the information sharing can be easily expanded by adding new agents and increasing the number of BB (Blackboard) levels. Moreover the subdivided levels of blackboard enhance the sensitivity of the intrusion detection. For the simulation, security models are constructed based on the DEVS (Discrete Event system Specification) formalism. The intrusion detection agent uses the ES (Expert System). The intrusion detection system detects the intrusions using the blackboard and the firewall responses to these detection information.

Characteristics Analysis on the Effects of Rotor Eccentricity in Squirrel-cage Induction Motor (회전자 편심을 고려한 농형 유도전동기의 특성해석)

  • Kim, Mi-Jung;Kim, Byong-Kuk;Jo, Won-Young;Cho, Yun-Hyun;Hwang, Don-Ha;Kang, Dong-Sik
    • Proceedings of the KIEE Conference
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    • 2006.04b
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    • pp.188-190
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    • 2006
  • This paper describes the effects of air gap eccentricity in induction machines. Asymmetric electro-magnetic force caused by the frictional worn bearing, rotor misalignment and unbalanced rotor etc. generates an asymmetrical operation, vibration and electro-magnetic noise. The need for detection of these rotor eccentricities has pushed the development of monitoring methods with increasing sensitivity and noise immunity. In this paper, we focus on investigating the asymmetrical operation considering of unbalanced magnetic force in squirrel-cage induction motor with 380 [V], 7.5 [kW], 4P, 1,768 [rpm]. The effects of the rotor eccentricity, magnetic force are investigated by finite element method (FEM).

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Planning Accelerated Degradation Tests: the Case of Gamma Degradation Process (열화가 감마과정을 따르는 경우 가속열화시험의 최적 계획)

  • Lim, Heonsang;Lim, Dae-Eun
    • Journal of Korean Society for Quality Management
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    • v.43 no.2
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    • pp.169-184
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    • 2015
  • Purpose: This paper is concerned with optimally designing accelerated degradation test (ADT) plans based on a gamma process for the degradation model. Methods: By minimizing the asymptotic variance of the MLE of the q-th quantile of the lifetime distribution at the use condition, the test stress levels and the proportion of test units allocated to each stress level are optimally determined. Results: The optimal plans of ADT are developed for various combination of parameters. In addition, a method for determining the sample size is developed, and sensitivity analysis procedures are illustrated with an example. Conclusion: It is important to optimally design ADT based on a gamma process under the condition that a degradation process should be always nonnegative and strictly increasing over time.

Characteristics Analysis on the Effects of Rotor Eccentricity in Squirrel-cage Induction Motor (회전자 편심을 고려한 농형 유도전동기의 특성해석)

  • Kim, Mi-Jung;Kim, Byong-Kuk;Hwang, Don-Ha;Kang, Dong-Sik;Cho, Yun-Hyun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.2
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    • pp.289-294
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    • 2007
  • This paper describes the effects of rotor eccentricity in squirrel cage induction machines. Asymmetric electro-magnetic force caused by the frictional worn bearing, rotor misalignment and unbalanced rotor etc. generates an asymmetrical operation, vibration and electro-magnetic noise. The need for detection of these rotor eccentricities has pushed the development of monitoring methods with increasing sensitivity and noise immunity. In this paper, we focus on investigating the asymmetrical operation considering of unbalanced magnetic pull in squirrel-cage induction motor with 380 [V], 7.5 [kW], 4P, 1,768 [rpm]. The effects of the non-symmetric rotor and magnetic force are simulated by finite element method (FEM) and tested using search coils for measuring the actual air-gap flux.

The Role of Scintimammography in the Diagnosis of Breast Cancer (유방암 진단에서 유방스캔의 역할)

  • Kim, In-Ju
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.4
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    • pp.213-223
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    • 2001
  • Breast cancer accounts for the higher proportion of cancer related deaths among women, and the incidence of this malignant disease is still increasing. The commonly used screening method is mammography. However, mammography has the drawback of low specificity in differentiating malignant and benign breast diseases. To overcome this low specificity of mammography, scintimammography using various radiopharmaceuticals such as Thallium-201, Tc-99m MIBI, Tc-99m tetrofosmin and Tc-99m MDP was introduced and now actively under the investigation. Several studios have shown that high sensitivity and specificity in detection of primary breast cancer and axillary lymph node metastases using these radiopharmaceuticals. Scintimammography may play important roles in the diagnosis of primary breast cancer, evaluation of the patients with high risk, determining axillary lymph node metastasis, evaluation of the response to chemotherapy, determining the extent of disease, and surveillance of local recurrence. In the future, we should investigate the prognostic role of scintimammography after treatment of breast cancer patients and cost-effectiveness of scintimammography in the detection of primary breast cancer.

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