• Title/Summary/Keyword: self-administration

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The Effects of Self-administration of Methamphetamine on Serotonin Receptors Level in Rat Brain (메스암페타민 자발섭취가 흰쥐 뇌조직 중 세로토닌 수용체에 미치는 영향)

  • 박기숙;홍진태;한진이;김혜진;김용규;이종권;안광수;이선희
    • Biomolecules & Therapeutics
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    • v.9 no.2
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    • pp.88-95
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    • 2001
  • (+)-Methamphetamine (METH) is a psychostimulant, which has been the most popular abused drug in Korea. The rewarding mechanism in METH abuse has been reported to be mediated by dopaminergic system. Recently, it has been reported that dopamine releaser (phentermine) plays a dominant role in the discriminative stimulus effects of METH, whereas 5-HT releaser (fenfluramine) can strongly modify METH self-administration. The present study is designed to assess the behavioral changes and the changes of the serotonin receptors in the brains of rats administered repeated of self-administered METH. The repeated administration of 1.0 mg/kg/day METH for 12 days increased locomotor activities, and there was no difference between i.v. and i.p. treatment. Rats had actively acquired METH self-administration for 3 weeks at 0.1 or 0.2 mg/kg/injection. Whereas, it was taken few days to acquire sucrose pellet self-administration. The binding of [$^3$H]-8-hydroxy-DPAT (5-H $T_{1A}$ receptors) and [$^3$H]-5-carboxytryptamine (5-H $T_{1B}$ receptors) to brain sections was examined. Both passive administration and self-administration of METH did not change significantly the serotonin receptors levels in hippocampus, striatum and nucleus accumbens. These results suggest that serotonin receptors may not change in the acquisition period of METH self-administration, and we are trying to investigate the serotonin receptors levels of brain in rats maintained of METH self-administration.n.n.

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Evaluation on the Abuse Liability of Ephedrine Using Rats (흰쥐를 이용한 에페드린의 약물남용가능성 평가)

  • 류승렬;김혜진;홍진태;이종권;이선희;이병무;김부영
    • YAKHAK HOEJI
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    • v.43 no.5
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    • pp.682-688
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    • 1999
  • Abuse liability of ephedrine was investigated by measurement of locomotor activity and self-administration in Sprague-Dawley rats. Locomotor activity was determined in rats treated with 3, 10 and 30 mg/kg ephedrine for 14 days. Self-administration by ephedrine (0.23, 1 and 2.3 mg/kg) was examined in food-trained rats. We also examined effect of dopamine receptor antagonist (spiperone, $30{\;}\mu\textrm{g}/kg$) on the ephedrine-induced response of self-administration. Body weight was not statistically difference between control and ephedrine treatment group, but locomotor activity was dose-dependently increased. Self-administration for ephedrine was decreased in the early response (day 1 and 2) but the response was increased by higher dose of ephedrine. Self-administration was decreased by dopamine receptor antagonist (spiperone). These data showed that ephedrine increased locomotor activity and induced response of self-administration, and the effects of ephedrine were partially related to the dopaminergic system, which suggest the ephedrine may have abuse liability.

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Social Identity and Regulatory Focus: Can Collective Orientation Influences Consumers' Message Evaluation?

  • Park, Sangwoo;Heo, Dakyeong;Shin, Dongwoo
    • Asia Marketing Journal
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    • v.21 no.1
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    • pp.89-112
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    • 2019
  • To investigate the interplay between individual and collective self-regulations, the authors propose a dialectic process that describes the changes in the locus of self-regulations between individual self and collective self. The results from three studies display a strong support for the two sets of hypotheses drawn from the proposed process. Our findings demonstrate that consumers can move the locus of self-regulation from individual-self to collective-self when a social identity is activated (preliminary study and study1). Further examination of regulatory swing between individual and collective regulatory orientations revealed group identification as a key variable in determining the locus of self-regulation (study2). While a consumer with a high level of group identification changes her locus of self-regulation from an individual to a collective (a regulatory shift) and evaluated messages and products framed consistent with their group orientation, a consumer with low level of group identification maintains her locus of self-regulation in her personal level of self (a regulatory preservation) and evaluated messages and products framed consistent with their personal regulatory focus.

Customer Acceptance of Self-service Technologies in Retail: A Case of Convenience Stores in China

  • Fang Lyu;Hyun-A Lim;Jaewon Choi
    • Asia pacific journal of information systems
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    • v.29 no.3
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    • pp.428-447
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    • 2019
  • This paper investigates how firms increase customer acceptance of self-service technologies in retail, and the impact of self-efficacy on customer experience, satisfaction, and loyalty. We conducted our empirical research by administering 308 questionnaires to customers of self-service convenience stores in China. We employed a structural equation model to analyze the relationship between service quality, revisit intention, and word of mouth. The results indicate that perceived service quality significantly influences customer satisfaction, with the service quality of self-service retail and experience value being important factors in consumer acceptance of self-service retail stores. Additionally, we investigated the relationship between customer experience value, satisfaction, and loyalty, and found that self-service retail stores exert a significant impact on perceived self-efficacy. Informed by the research on customer acceptance of self-service technologies in retail, promoting further development of self-service retail technologies can effectively aid companies in generating profit while offering more convenience to customers.

The Effects of Self-Regulated Learning on Career Decision-Making Efficacy through Positive and Negative Attitudes in the Fourth Industrial Era

  • Eom, Soyeon;Oh, Hyungjin;Jeong, Dongwook;Kim, Sohui;Hahm, Sangwoo
    • International Journal of Internet, Broadcasting and Communication
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    • v.15 no.1
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    • pp.203-210
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    • 2023
  • As the environment changes become more complex, learners should establish the learning strategy for the 4th industrial era and the post-COVID-19, also change. This paper focuses on the importance of self-regulated learning. Through this learning strategy, learners will form more positive attitudes and reduce negative attitudes toward the 4th industrial era. This attitude change will lead to an improvement in learners' career decision-making efficacy as a sense of future efficacy. As a result of the study, it was demonstrated that self-regulated learning improves career decision-making efficacy through the mediating effect of positive attitude formation toward the fourth industry. This article emphasizes the necessity of self-regulated learning as a valid learning strategy for the new era. The effect of self-regulated learning is explained as an improvement in attitude toward the future and a sense of efficacy. Through this learning strategy, learners' future performance could be improved.

The Influence of University Student's Perception on their External Image and Self Perfectionism on Depression (일부 대학생의 외적 이미지와 자기 완벽성에 대한 인식이 우울에 미치는 영향)

  • Jeon, Sang-Nam;Park, Jee-Eun;Hwang, Sung-Wan;Kim, Sun-Hee
    • The Korean Journal of Health Service Management
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    • v.6 no.1
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    • pp.53-63
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    • 2012
  • The purpose of this study is to examine the influence of external image and self perfectionism on the depression. The survey collected 240 subjects from 3 university students in Seoul, Korea. The research period was from May to June of 2011 and the collected data were analyzed using the SPSS 15.0. As a result of this research, those with lower self image level, those with higher self perfectionism increased the depression level. It is necessary to develop programs for university students considering the fact that external image and self perfectionism influence on the depression. Moreover, it should be developed that solutions can decrease psychological pressure and overcome overwhelming expectation.

Transformational Leadership and Organizational Citizenship Behavior : The Mediating Role of Self Leadership (변혁적리더십이 조직시민행동에 미치는 영향에 있어 셀프리더십의 매개효과에 관한 연구)

  • Park, Dong-Jin;Lee, Kwang-Hee;Jang, Eun-Young;Moon, Jung-Hwan
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.35 no.1
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    • pp.132-139
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    • 2012
  • The purpose of this study is to examine the effects of transformational leadership and organizational citizenship behavior. It also investigated the mediating effect of self leadership on the causal relationship between transformational leadership and organizational citizenship behavior. Research results, transformational leadership had a positive affected on the self leadership, The self leadership had a positive affected on organizational citizenship behavior. And transformational leadership did not make a significant impact on organizational citizenship behavior. Finally, the self leadership was a full mediator on the relationships between the transformational leadership and the organizational citizenship behavior. Based on these findings, the implications and the limitations of the study were presented including some directions for future studies.

The Effect of Ambient Sadness on Hedonic Choice

  • Choi, Nak-Hwan;Oyunbileg, Tamir;Tsogtbayar, Naranzul
    • Journal of Distribution Science
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    • v.13 no.3
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    • pp.11-19
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    • 2015
  • Purpose - This study examines the strength of sadness and the belief it will last, as regards the effects of the degree of self-extension to the sad-evoking event on choice behavior related to self-control dilemmas. Research Design, Data, and Methodology - In an experiment involving high and low self-extension groups, 261 undergraduates answered self-administered questionnaires. The hypotheses were tested using AMOS 19.0 and path analysis. Results - The positive relationship between the degree of self-extension to the sad-evoking event and hedonic vs. utilitarian food choices was mediated by the belief that the sadness will last. There is a significant indirect path from the degree of self-extension (to the sad-evoking event) to the strength of the sadness, and to the belief that it will last with respect to hedonic vs. utilitarian food choices. Conclusions - These results show that beliefs about sad emotion transience depend on both the degree of self-extension to the sad-evoking event and the strength of sadness, and that the belief that sad emotions are transient makes sad people susceptible to temptation when facing self-control related dilemmas.

A Study on the Image of Nurses and the Professional Self-Concept Perceived by Nursing Students (간호대학생의 전문직 자아개념과 간호사에 대한 이미지)

  • Yee, Jung-Ae
    • Journal of Korean Academy of Nursing Administration
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    • v.10 no.3
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    • pp.325-334
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    • 2004
  • Purpose: The purpose of this study was to identify the image of nurses and the professional self-concept perceived by nursing students. Method: The subjects included were 93 students. The research tool was the Professional Self-Concept of Nurses Instrument(PSCNI) by Arthur and Image of Nurses by Yang. Result: 1. The professional self-concept consisted of 4 factors : flexibility, satisfaction, competence, empathy. 2. The image of nurse consisted of 4 factors : official image, maternal image, professional image. unfavorable image. 3. The average item score of PSCNI was $2.94{\pm}30$. 4. The average item score of nurse' image was $3.63{\pm}46$ 5. The Professional self-concept of nurses(p=.0001) and image of nurses(p=.001) was found to significantly according to satisfaction for major. 6. The correlation between professional self-concept and image of nurses revealed correlation of r=.315(p=.004). Conclusion: There was a association between professional self concept of nurses, image of nurses and satisfaction for major. Therefore it is required to develop education program and strategy that helps establish satisfaction for major so that nursing students can experience firm professional self concept and positive image of nursing.

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Effects of Mongolian Startup's Motivation, Self-Efficacy and Entrepreneurial Orientation on Performance: gender differences (몽골 창업가들의 창업동기, 자기효능감 및 기업가지향성과 창업성과간의 관계: 성별 차이)

  • Delgermaa Otgon;Shin-Hyung Kang;Sangmoon Park
    • Asia-Pacific Journal of Business
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    • v.13 no.4
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    • pp.123-134
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    • 2022
  • Purpose - The purpose of this study is to investigate the effects of entrepreneurial motivation, self-efficacy, and entrepreneurial orientation on the performance of Mongolian entrepreneurs. Design/methodology/approach This study collected data from a survey on 236 entrepreneurs in Mongolia and investigate research hypotheses by empirical analysis. Findings It was found that entrepreneurial motivation (independence, opportunity-driven, achievement motivation) had a positive effect on the startups' performances, and necessity-driven motivation did not have a significant effect on the startups' performances. Entrepreneurial self-efficacy and entrepreneurial orientation had a positive effect on performance of startups. There are differences by gender on the relationships between entrepreneurial motivations and startup performances. Research implications or Originality This paper investigates the effects of entrepreneurial motivation, self-efficacy, and entrepreneurial orientation on the performance of startups in Mongolian.