• Journal of Veterinary Science
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• v.22 no.4
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• pp.45.1-45.13
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• 2021

Background: Peste des petits ruminants (PPR) is an infectious disease caused by the peste des petits ruminants virus (PPRV) that mainly produces respiratory symptoms in affected animals, resulting in great losses in the world's agriculture industry every year. Single-domain variable heavy chain (VHH) antibody fragments, also referred to as nanobodies, have high expression yields and other advantages including ease of purification and high solubility. Objectives: The purpose of this study is to obtain a single-domain antibody with good reactivity and high specificity against PPRV. Methods: A VHH cDNA library was established by immunizing camels with PPRV vaccine, and the capacity and diversity of the library were examined. Four PPRV VHHs were selected, and the biological activity and antigen-binding capacity of the four VHHs were identified by western blot, indirect immunofluorescence, and enzyme-linked immunosorbent assay (ELISA) analyses. ELISA was used to identify whether the four VHHs were specific for PPRV, and VHH neutralization tests were carried out. ELISA and western blot analyses were used to identify which PPRV protein was targeted by VHH2. Results: The PPRV cDNA library was constructed successfully. The library capacity was greater than 2.0 × 10⁶ cfu/mL, and the inserted fragment size was approximately 400 bp to 2000 bp. The average length of the cDNA library fragment was about 1000 bp, and the recombination rate was approximately 100%. Four single-domain antibody sequences were selected, and proteins expressed in the supernatant were obtained. The four VHHs were shown to have biological activity, close affinity to PPRV, and no cross-reaction with common sheep diseases. All four VHHs had neutralization activity, and VHH2 was specific to the PPRV M protein. Conclusions: The results of this preliminary research of PPRV VHHs showed that four screened VHH antibodies could be useful in future applications. This study provided new materials for inclusion in PPRV research.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.20 no.2
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• pp.31-44
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• 2009

The conspectus, based on a set number of subject descriptors derived essentially from LC subject classifications, provides a consistent framework within which libraries could report subject intensity. While library collection development has been benefitted by using this conspectus, its effectiveness in this digital era is under controversy. The purpose of this study is to survey the concepts and the various types of conspectus in library collection development and to test the applicability of a revised conspectus model to electronic resource management in libraries. For this, the focus was especially put on investigating the characteristics of electronic resources as considered the collection depth usually identified in collection development policies. Previous research has been also surveyed to consolidate their outcomes in order to design a matrix model of conspectus, which put the characteristics, persistence, and collection level in consideration in oder for the design of the conspectus model.

• Journal of the Korean Society for information Management
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• v.21 no.2
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• pp.45-67
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• 2004

The purposes of this study are to compare and analyze the evaluation indicators for selection of journal suggested by scholars and organizations and to prepare theoretical background for the ideal model to meet opposing paradigms of collection management in academic libraries. A web survey method was employed to investigate applications of various selection criteria (27 for printed and 37 for electronic academic Journal) from the top 40 academic libraries in Korea. In addition, data were analysed statistically using factor analysis, t-test, Analysis of Variance(ANOVA), and Spearman's Rank Oder Correlation. The mean ranking for 9 evaluation indicators for printed were as follows: subscribing volumes per departments, degree of use, selection authority, electronic/print bundle, ISI impact factor, Internationality and reputation, costs for subscription, ILL ＆ DDS, space considerations for printed materials. But, 11 evaluation indicators for electronic were as follows : costs for subscription, accessibility, electronic/print bundle, consortia, selection authority, access expandability, subscribing volumes per departments, scholarly features of the university, ISI impact factor, ILL ＆ DDS, internationality and reputations.

• Journal of the Korean Society for information Management
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• v.40 no.4
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• pp.279-306
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• 2023

This study analyzed bibliographic attributes related to the selection and use of reading materials based on data on books borrowed or purchased together in order to understand the properties of reading materials that have complex user needs from various perspectives. As a result of creating co-occurrence matrices of bibliographic attribute terms by dividing them into 26 sub-attribute units related to KDC main class, target reader, and user age, and performing network analyses, the details and prominent mediating role of bibliographic attributes of reading materials were identified. The results of this study will be helpful in designing facets of reading information systems, including library OPAC, in the future.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.3
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• pp.254-284
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• 2015

Objectives: There is a requirement to select target materials for mutagenicity(Genotoxicity) testing, so we determined to set the test priorities of them by searching the related database. Methods and Results: We searched a number of databases to find information on mutagenicity tests with chemicals under the Occupational Safety and Health Act(OSH Act), such as KOSHANET, National Toxicology Program(NTP), European Chemicals Agency(ECHA), US National Library of Medicine(NLM), and Genetic Toxicology Data Bank(GENE-TOX), as well as ChemIDplus webpage, and presented the information. Also we anticipated their hazards with ACToR sites to confirm the 58 mutagenicity(Genotoxicity) tests we will perform. Conclusions: We presented target materials for mutagenicity testing with specific GLP tests consisting of reverse mutation(Ames), chromosomal aberration and micronucleus test.

• Journal of Korean Library and Information Science Society
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• v.4
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• pp.1-38
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• 1977

This paper intend to analyze, review and point out the actual conditions of "Reserve Book System" of university libraries in Korea, then to present several proposals. I took six national universities and six private universities as researching objects and the materials were collected by questionnaires. 1) There are so many libraries which have no seperate reserve books room, while every colleges, and their departments are putting into forces the reserve book system. This makes many unresonable problems. 2) Many volumes were not adequate to the courses of each depertment and so many problems arose to set up reserve books owing to Lhe lack of library budget. 3) Insincerities of professors and librarians make no good conditions for the reserve book system. 4) For insufficiency of understanding about the reserve book system cf professors and students with university authorities, we must persuade and guide them about this system. 5) We imust evaluate about the problems of the reserve book system. I show the methods which is necessary to solve the problems of this system in the following. 1) As to methods of improving the field of menagement for running about the reserve book system, a) Establishment of the independent reserve books room. b) Gradual expansion of the reserve book system. c) Evaluation of the actual using of reserve books. 2) As to contents to improve the reserve book system, a) Improving the selection method of reserve books. b) Increasing the library budget enable to purchase more reserve books. c) Making more close connections between the curricula ard reserve books. 3) Settlment of coordinating system for carrying out reserve book system, a) We must have mutual understanding and co-operation among university authorities, faculties and libraries. b) We must have co-operation between professors and librariars.ibrariars.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.32 no.4
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• pp.213-229
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• 2021

The purpose of this study is to explore the establishment and administrative strategies for shared repositories for academic libraries in Korea, using the US ReCAP (Research Collections and Preservation Consortium) Project as a case study. The US ReCAP Project was a collaboration between the New York Public Library and the university libraries of Columbia University, Harvard University, and Princeton University. In-depth interviews were conducted with librarians and administrators in charge of the ReCAP Project to understand the original vision of the project, as well as how the strategy and approach evolved over the years. The analysis results revealed that shared repositories for libraries have evolved into shared collections enabling shared use. But shared repositories require a central management system to be successful in the long-term. Additionally, findings showed that the shared repository filled more quickly than anticipated. This in turn required collaborative planning on shared collection development and selection policies to determine which materials to send to the shared repository.

• Journal of Korean Library and Information Science Society
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• v.44 no.1
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• pp.409-432
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• 2013

The purpose of this study is to examine 5 writing guidelines of reference collection development policy(RCDP) and to identify major elements of RCDP through the comparison and analysis of 24 RCDP in academic libraries in the U.S. As a result of this study, a total of 9 elements(5 core elements and 4 selective elements) were identified. Five core elements were (1) introduction, (2) scope, size, and level, (3) format, (4) types, and (5) management(i.e., selection, weeding, evaluation, and responsibilities) of reference collection. The results of this study would be helpful to those academic libraries which are planning to write RCDP in academic libraries in the near future.

• Journal of the Korean Society for Library and Information Science
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• v.38 no.4
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• pp.231-249
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• 2004

To develope a scheme of an efficient archival arrangement and management, this study, through the methodology in France which named 'archives' for the first time and produce the best qualified archivistes every year from ENC(Ecole Nationales des Charles) , has started the problem of the adjustment of terminology which must be basically established, the foundation and history of archives, and their kinds and characteristics in the view of periods, contents and materials. After, for the core of an efficient archival arrangement and management, the study goes on theoretical and practical sides : educational courses for archival studies in part, appraisal, selection and collection, arrangement, communication and valorization of archives in other part.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.19 no.2
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• pp.23-43
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• 2008

Knowledge resources are classified with two groups, the records produced by internal parts of company and general information materials from external organizations. Production, acquisition, storage, retrieval and utilization patterns of two groups became similar due to digitization of knowledge resources. And separated RM and IM should be changed integrated management concept. This paper compares RM and IM based on KM governance strategy and several methods to integrate RM and IM. Especially the selection and identification of knowledge resources, information systems to be integrated and the methods of integration and integrators of public enterprises are presented.