• Korean Journal of Construction Engineering and Management
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• v.13 no.3
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• pp.14-24
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• 2012

Recently, a delivery system has been rapidly changed in the global construction market. Also, construction projects are becoming bigger and more technology-intensive. A lot of projects have been delivered by Design-Build(DB) System; from the standpoint of cost, approximately 40% of delivered constructions by a Public Procurement Service were DB in 2009. Nevertheless, the achievement has not surpassed our expectations on management of the project cost. On the characteristic of DB, the reasons why that happens are that projects contract have been signed after the Design Development Stage; the insufficient review about new technology and up-to-date construction methods; a lack of discussion in process of design. Those reasons cause a risk of increasing Cost of the projects. In order to solve these problems, it is desirable to find Cost-increasing factors in promoting the projects and select on the order of priority for Risk-Factor with careful management. Therefore, this study analyzed the weight of each phase of the project on the authority of properties of DB project, and identified Risk-factors which is increasing the cost on the aspect of project management. Based on this analysis, the impact assessment of Risk-factor is evaluated through the Failure Mode and Effect Analysis(FMEA).

• KOREAN JOURNAL OF CROP SCIENCE
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• v.51 no.5
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• pp.458-465
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• 2006

This study was carried out to evaluate the nutritional properties of quality protein maize (QPM) and to select the elite lines for corn breeding. Two laboratory procedures for simultaneous identification of QPM and lysine content analysis were performed. The $BC_{1}F_{2}$ lines of KS5/QPM and KS135/QPM were analyzed with opaque-2(o2) specific SSR marker in order to differentiate the opaque-2 carrying QPM lines from the non-opaque genotypes. Although no significant difference in protein content, significant differences in lipid, ash, and crude fiber contents were observed. The composition of unsaturated fatty acid of QPM lines was slightly lower than non-QPM lines, but there was no significant difference. Sulphur-containing amino acids such as methionine and cystine showed no difference between QPM and non-QPM lines. However, lysine content of QPM lines was 38% higher than that of non-QPM lines, and the essential amino acid content of QPM lines (28.1%) was higher compared to non-QPM lines (27.1%).

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1162-1162
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• 2001

Whereas NIR spectroscopy has been applied in agriculture for more than 20 years, few studies refer to those plant substances occurring only in smaller amounts. Nevertheless there is a growing interest today to support efficiently activities in the production of high-quality medicinal and spice plants by this fast and non-invasive method. Therefore, it was the aim of this study to develop new NIR methods for the reliable prediction of secondary metabolites found as valuable substances in various plant species. First, sophisticated NIR methods were established to perform fast quality analyses of intact fennel, caraway and dill fruits deriving from single-plants [1]. Later on, a characterization of several leaf drugs and the corresponding fresh material has been successfully performed. In this context robust calibrations have been developed for dried peppermint, rosemary and sage leaves for the determination of their individual essential oil content and composition [2]. A specially adopted NIR method has been developed also for the analysis of carnosic acid in the leaves of numerous rosemary and sage gene bank accessions. Carnosic acid is an antioxidative substance for which several health promoting properties including cancer preservation are assumed. Also some other calibrations have been developed for non-volatile substances such as aspalathin (in unfermented rooibos leaves), catechins (in green tea) and echinacoside (in different Echinacea species) [3]. Some NIR analyses have also been successfully performed on fresh material, too. In spite of the fact that these measurements showed less accuracy in comparison to dried samples, the calibration equations are precise enough to register the individual plant ontogenesis and genetic background. Based on the information received, the farmers and breeders are able to determine the right harvest time (when the valuable components have reached their optimum profile) and to select high-quality genotypes during breeding experiments, respectively. First promising attempts have also been made to introduce mobile diode array spectrometers to collect the spectral data directly on the field or in the individual natural habitats. Since the development of reliable NIRS methods in this special field of application is very time-consuming and needs continuous maintenance of the calibration equations over a longer period, it is convenient to supply the corresponding calibration data to interested user via NIRS network. The present status of all activities, preformed in this context during the last three years, will be presented in detail.

• Journal of Periodontal and Implant Science
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• v.41 no.2
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• pp.73-78
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• 2011

Purpose: For periodontal tissue engineering, it is a primary requisite and a challenge to select the optimum types of cells, properties of scaffold, and growth factor combination to reconstruct a specific tissue in its natural form and with the appropriate function. Owing to fundamental disadvantages associated with using a two-dimensional substrate, several methods of seeding cells into three-dimensional scaffolds have been reported and the authors have asserted its usefulness and effectiveness. In this study, we explore the cell attachment of periodontal ligament fibroblasts on nanohydroxyapatite (n-HA) scaffold using avidin biotin binding system (ABBS). Methods: Human periodontal ligament fibroblasts were isolated from the health tooth extracted for the purpose of orthodontic procedure. HA nanoparticles were prepared and $Ca(NO_3)_2-_4H_2O$ and $(OC_2H_5)_3P$ were selected as precursors of HA sol. The final scaffold was 8 mm in diameter and 3 mm in height disk with porosity value of 81.55%. $1{\times}10^5$ periodontal ligament fibroblasts were applied to each scaffold. The cells were seeded into scaffolds by static, agitating and ABBS seeding method. Results: The number of periodontal ligament fibroblasts attached was greater for ABBS seeding method than for static or agitating method (P<0.05). No meaningful difference has been observed among seeding methods with scanning electron microscopy images. However, increased strength of cell attachment of ABBS could be deduced from the high affinity between avidin and biotin ($Kd=10^{-15}\;M$). Conclusions: The high-affinity ABBS enhances the ability of periodontal ligament fibroblasts to attach to three-dimensionally constructed n-HA scaffold.

• Journal of the Korea Concrete Institute
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• v.13 no.5
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• pp.491-498
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• 2001

The failure phenomenon of overlaid concrete structures, such as surface crack and peel-off failure in the contact zone, was investigated due to temperature shock(rainfall). To investigate this failure phenomenon, the surface tensile stress, and the shear stress, the vertical tensile stress in the contact zone were analysed using the non-linear stress-strain relationship of material such as strain-hardening- and strain-softening diagrams. Rainfall intensity, overlay thickness and overlay material were the main variables in the analyses. It is assumed that the initial temperature of overlaid concrete structures was heated up to 55$\^{C}$ by the solar heat. With a rain temperature 10$\^{C}$ and the rainfall intensity of nR=1/a, tR=10min, 60min, the stress states of overlaid concrete structures were calculated. The result shows that only fictitious cracks occurred in the overlay surface and no shear bond failure occurred in the contact zone. The vortical tensile stress increasing with overlay thickness was proved to be the cause of peel-off failure in the contact zone. The formulae for relationship between the vertical tensile stress and overlay thickness, material properties were derived. Using this formulae, it is possible to select proper material and overlay thickness to prevent failure in the contact zone due to temperature shock caused by rainfall.

• The KIPS Transactions:PartB
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• v.13B no.4 s.107
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• pp.353-360
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• 2006

This paper presents a robust algorithm for segmenting a vehicle license plate area from a road image. We consider the features of license plates in three aspects : 1) edges due to the characters in the plate, 2) colors in the plate, and 3) geometric properties of the plate. In the preprocessing step, we compute the thresholds based on each feature to decide whether a pixel is inside a plate or not. A statistical approach is applied to the sample images to compute the thresholds. For a given road image, our algorithm binarizes it by using the thresholds. Then, we select three candidate regions to be a plate by searching the binary image with a moving window. The plate area is selected among the candidates with simple heuristics. This algorithm robustly detects the plate against the transformation or the difference of color intensity of the plate in the input image. Moreover, the preprocessing step requires only a small number of sample images for the statistical processing. The experimental results show that the algorithm has 97.8% of successful segmentation of the plate from 228 input images. Our prototype implementation shows average processing time of 0.676 seconds per image for a set of $1280{\times}960$ images, executed on a 3GHz Pentium4 PC with 512M byte memory.

• Korean Journal of Biological Psychiatry
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• v.4 no.2
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• pp.198-210
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• 1997

To examine the double-faced thymoleptic(antidepressant and antimanic) effects of risperidone in mood disorders, this article reviews the psychotropic-induced mania, thymoleptic effects of antipsychotics, therapeutic effects of risperidone and risperidone(RIS)-induced mania(RIM) in mood disorders, risk factors of RIM, possible neurochemical mechanism of these thymoleptic effects, pathophysiological and clinical significance of thymoleptic effects, and suggestive clinical guideline of RIS in mood disorders. RIS appeared effective for bipolar disorder at a lower dose than that recommended for schizophrenia, especially in the cases of maintenance of mood stabilizers, and gradual titration from low doses. Manic induction/exacerbation can occur by chance during RIS treatment in mood disorders, schizoaffective disorders, and schizophrenias. The possible risk factors for RIM are refractory mood disorder, especially in bipolar I disorder with poor initial response ; refractory schizoaffective disorders, especially in bipolar type with poor initial response ; refractory chronic schizophrenias, especially with initial responses ; psychotic features ; higher initial doses ; rapid titration ; combined therapy with antidepressants in refractory depression ; and RIS monotherapy in mania/hypomania. RIS is a drug that preferentially block 5-HT2 receptors. The effects of low dose are due mainly to the blockade of 5-HT2 receptors. There are more gradual increase in D2 blockade with increasing dose and this D2 blocking properties become apparent at higher doses. This may be related to a modulation of dopaminergic transmission by 5-HT2 antagonism at lower doses with the direct action of RIS on DA receptors coming into play at higher dose. The serotonergic antagonistic effect may be important for its effects on depressive symptoms. This, together with adequate blo-ckade of D2 receptors, may not necessarily lead to destabilization of mood disorder, but rather to more therapeutic effects. Therefore, this dose-receptor affinity relationship with both antidepressant and antimanic effects according to treatment duration can explain a continuum of antidepressant effect, antimanic effect, behavioral stimulation, and manic/hypomanic induction/exacerbation. It was the recognition of a useful psychiatric side effects by a thoughtful observer with fertile minds that led to their ultimate utilization as psychotropic drugs, i.e., phenothiazine, MAOI, TCA, and lithium. And, in vivo pharmacological challenge by novel psychotropics, as a neurochemical probe, with more specific actions is a useful tool to select pharmacologically homogeneous subgroup of the same phenotypical(clinical) condition, to further study the unknown underlying pathogenesis of various mental illnesses. Finally, RIS may be a useful alternative or adjunctive drug for patients with mood disorders without psychotic features or refractory to treatment with standard antipsychotic drugs. The more conservative doses(tirated slowly from 1-3 mg/d) of RIS, and maintenance of mood stabilizer in the cases with risk factors of RIM are recommended in mood disorder.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.6
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• pp.577-584
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• 1994

A field trial was carried out to select suitable crops for diverted upland from paddy field and to investigate response of several forage crops to soil properties and ground water levels of the diverted upland at Suwon area of Korea in 1992 and 1993. Experiments were conducted in sandy loam plot and comparatively clay loam plot having higher ground water level. Rye (Paldang), triticale (Shinki), italian ryegrass (Tetraflorum) were used as wintering forage crops and maize(Suwon 19), sorghum-sudangrass hybrid(Pioneer855F), pearl millet(Suwon 6), japanese millet (King) were used as summer forage crops. Growth and yield of forage crops were better and higher in sandy loam soil having low ground water level. Among wintering forage crops, triticale recorded the highest forage yield. Rye showed high forage yield in sandy loam soil and italian ryegrass hardly survived in diverted upland of Suwon area during winter. Among summer forage crops, forage yield of sorghum-sudangrass hybrid was highest. Yield of japanese millet was not affected by soil conditions in both plots. Yields of pearl millet and maize remained relatively low in both plots.

• Journal of KIISE:Computer Systems and Theory
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• v.35 no.5
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• pp.213-222
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• 2008

This paper is related to color image segmentation and textile texture mapping for the 2D virtual wearing system. The proposed system is characterized as virtually wearing a new textile pattern selected by user to the clothing shape section, based on its intensity difference map, segmented from a 2D clothes model image using color image segmentation technique. Regardless of color or intensity of model clothes, the proposed system is possible to virtually change the textile pattern or color with holding the illumination and shading properties of the selected clothing shape section, and also to quickly and easily simulate, compare, and select multiple textile pattern combinations for individual styles or entire outfits. The proposed system can provide higher practicality and easy-to-use interface, as it makes real-time processing possible in various digital environment, and creates comparatively natural and realistic virtual wearing styles, and also makes semi-automatic processing possible to reduce the manual works to a minimum. According to the proposed system, it can motivate the creative activity of the designers with simulation results on the effect of textile pattern design on the appearance of clothes without manufacturing physical clothes and, as it can help the purchasers for decision-making with them, promote B2B or B2C e-commerce.

• Journal of Microbiology and Biotechnology
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• v.19 no.9
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• pp.987-996
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• 2009

Aspergillus niger GH1 previously isolated and identified by our group as a wild tannase producer was grown under solid-state (SSC) and submerged culture (SmC) conditions to select the enzyme production system. For tannase purification, extracellular tannase was produced under SSC using polyurethane foam as the inert support. Tannase was purified to apparent homogeneity by ultrafiltration, anion-exchange chromatography, and gel filtration that led to a purified enzyme with a specific activity of 238.14 IU/mg protein with a final yield of 0.3% and a purification fold of 46. Three bands were found on the SDS-PAG with molecular masses of 50, 75, and 100 kDa. PI of 3.5 and 7.1% N-glycosylation were noted. Temperature and pH optima were 600e and 6.0 [methyl 3,4,5-trihydroxybenzoate (MTB) as substrate], respectively. Tannase was found with a $K_M$ value of $0.41{\times}10^{-4}M$ and the value of $V_{max}$ was $11.03{\mu}$moL/min at $60^{\circ}C$ for MTB. Effects of several metal salts, solvents, surfactants, and typical enzyme inhibitors on tannase activity were evaluated to establish the novelty of the enzyme. Finally, the tannase from A. niger GH1 was significantly inhibited by PMSF (phenylmethylsulfonyl fluoride), and therefore, it is possible to consider the presence of a serine or cysteine residue in the catalytic site.