• The Korean Journal of Zoology
• /
• v.7 no.1
• /
• pp.1-5
• /
• 1964

GamnH-irradiated aqueous solutions of triglycine were studied using low voltage electrophoresis, paper chromatography, and determination of carbonyl compound. Four generalizations can be made as follows: 1. One component from irradiated triglycine formed a complex with copper ions and had higher electronegativity than did triglycine. 2. Five components from irradiated triglycine were separated by paper chromatography; of these, two were identified. 3. Carbonyl compound formation in irradiated triglycine increased up to $5{\times}10^{20}\;ev/ml$ and decreased at higher doses up to $1.9{\times}10^{21}\;ev/ml$ indicating its participation in secondary reaction in the complex system. 4. The possibility of hydrolytic brcabtgc of peptide bond was indicated by the separation of glycine from irradiated triglycine.lycine.

• Journal of Microbiology and Biotechnology
• /
• v.23 no.9
• /
• pp.1206-1211
• /
• 2013

The selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity. In the course of screening for PTP1B inhibitory fungal metabolites, the organic extracts of several fungal species isolated from marine environments were found to exhibit significant inhibitory effects, and the bioassay-guided investigation of these extracts resulted in the isolation of fructigenine A (1), cyclopenol (2), echinulin (3), flavoglaucin (4), and viridicatol (5). The structures of these compounds were determined mainly by analysis of NMR and MS data. These compounds inhibited PTP1B activity with 50% inhibitory concentration values of 10.7, 30.0, 29.4, 13.4, and 64.0 ${\mu}M$, respectively. Furthermore, the kinetic analysis of PTP1B inhibition by compounds 1 and 5 suggested that compound 1 inhibited PTP1B activity in a noncompetitive manner, whereas compound 5 inhibited PTP1B activity in a competitive manner.

• Journal of Powder Materials
• /
• v.12 no.3
• /
• pp.179-185
• /
• 2005

As the electrodes of secondary battery are made with sulfur compounds, excellent electrode system of environmental non-toxicity, high specific energy density and low material cost can be obtained. In this study, the $FeS_2$ fine compound powders for active material in the battery were synthesized by mechanical alloying. Fine Fe-53.5 wt.%S powders of 450 nm of mean size were fabricated by mechanical alloying for 60 hours at the horizontal attritor. As the mechanical alloying time increases, particle size of Fe-53.5 wt.%S was decreased and steady state of Fe-53.5 wt.%S compound powders was obtained at 30 hours. Fe-53.5 wt.%S cathode shows the excellent discharge capacity (1011 mAh/g).

• 한국연소학회:학술대회논문집
• /
• 2006.04a
• /
• pp.149-156
• /
• 2006

Structure of edge flame established in a mixing layer, formed between two uniformly flowing pure $CH_4$ and pure $O_2$ streams, is numerically investigated by employing a detailed methane-oxidation mechanism. The numerical results exhibited the most outstanding distinction of using pure oxygen in the fuel-rich premixed-flame front, through which the carbon-containing compound is found to leak mainly in the form of CO instead of HC compounds, contrary to the rich $CH_4-air$ premixed flames in which $CH_4$ as well as $C_2H_m$ leakage can occur. Moreover, while passing through the rich premixed flame, a major route for CO production, in addition to the direct $CH_4$ decomposition, is found to be $C_2H_m$ compound formation followed by their decomposition into CO. Beyond the rich premixed flame front, CO is further oxidized into $CO_2$ in a broad diffusion-flame-like reaction zone located around moderately fuel-rich side of the stoichiometric mixture by the OH radical from the fuel-lean premixed-flame front. Since the secondary CO production through $C_2H_m$ decomposition has a relatively strong reaction intensity, an additional heat-release branch appears and the resulting heat-release profile can no longer be seen as a tribrachial structure.

• Biomolecules & Therapeutics
• /
• v.23 no.5
• /
• pp.414-420
• /
• 2015

Flavonoids, such as fisetin (3,7,3',4'-tetrahydroxyflavone), are plant secondary metabolites. It has been reported that fisetin is able to perform numerous pharmacological roles including anti-inflammatory, anti-microbial, and anti-cancer activities; however, the exact anti-inflammatory mechanism of fisetin is not understood. In this study, the pharmacological action modes of fisetin in lipopolysaccharide (LPS)-stimulated macrophage-like cells were elucidated by using immunoblotting analysis, kinase assays, and an overexpression strategy. Fisetin diminished the release of nitric oxide (NO) and reduced the mRNA levels of inducible NO synthase (iNOS), tumor necrosis factor (TNF)-${\alpha}$, and cyclooxygenase (COX)-2 in LPS-stimulated RAW264.7 cells without displaying cytotoxicity. This compound also blocked the nuclear translocation of p65/nuclear factor (NF)-${\kappa}B$. In agreement, the upstream phosphorylation events for NF-${\kappa}B$ activation, composed of Src, Syk, and I${\kappa}B{\alpha}$, were also reduced by fisetin. The phospho-Src level, triggered by overexpression of wild-type Src, was also inhibited by fisetin. Therefore, these results strongly suggest that fisetin can be considered a bioactive immunomodulatory compound with anti-inflammatory properties through suppression of Src and Syk activities.

• Journal of the Korean Society of Combustion
• /
• v.11 no.1
• /
• pp.19-26
• /
• 2006

Structure of edge flame established in a mixing layer, formed between two uniformly flowing pure $CH_4$ and pure $O_2$ streams, is numerically investigated by employing a detailed methane-oxidation mechanism. The numerical results exhibited the most outstanding distinction of using pure oxygen in the fuel-rich premixed-flame front, through which the carbon-containing compound is found to leak mainly in the form of CO instead of HC compounds, contrary to the rich $CH_4-air$ premixed flames in which $CH_4$ as well as $C_2H_m$ leakage can occur. Moreover, while passing through the rich premixed flame, a major route for CO production, in addition to the direct $CH_4$ decomposition, is found to be $C_2H_m$ compound formation followed by their decomposition into CO. Beyond the rich premixed flame front, CO is further oxidized into $CO_2$ in a broad diffusion-flame-like reaction zone located around moderately fuel-rich side of the stoichiometric mixture by the OH radical from the fuel-lean premixed-flame front. Since the secondary CO production through $C_2H_m$ decomposition has a relatively strong reaction intensity, an additional heat-release branch appears and the resulting heat-release profile can no longer be seen as a tribrachial structure.

• Journal of the Korean Chemical Society
• /
• v.34 no.6
• /
• pp.534-538
• /
• 1990

Chromium(Ⅵ) compound, [$C_9H_7$NH]$_2Cr_2O_7$ has been prepared by the reaction of isoquinoline with chromium trioxide under the presence of water. [$C_9H_7$NH]$_2Cr_2O_7$ is nonhydroscopic and dissolved in water very well. Structure of [$C_9H_7$NH]$_2Cr_2O_7$ is identified by FTIR spectra and elemental analysis data. The ability of [$C_9H_7$NH]$_2Cr_2O_7$ for the oxidation of alcohols were examined in methylene chloride. [$C_9H_7$NH]$_2Cr_2O_7$ was found as efficient oxidizing agent for the conversion of allyl, primary and secondary alcohols to the corresponding aldehydes or ketones.

• Journal of Microbiology
• /
• v.45 no.3
• /
• pp.262-267
• /
• 2007

During a screening program, an actinomycete strain isolated from the Egyptian soil was investigated for its potential to show antimicrobial activity. The identification of this isolate was performed according to spore morphology and cell wall chemo-type, which suggested that this strain is a streptomycete. Further cultural, physiological characteristics and the analysis of the nucleotide sequence of the 16S rRNA gene (1480 bp) of this isolate indicated that this strain is identical to Streptomyces violaceusniger (accession number EF063682) and then designated S. violaceusniger strain HAL64. In its culture supernatant, this organism could produce one major compound strongly inhibits the growth of Gram-positive but the inhibition of Gram-negative indicator bacteria was lower. The antibiotic was separated by silica gel column chromatography and then purified on a sephadex LH-20 column and finally the purity was checked by HPLC. The chemical structure of the purified compound was determined using spectroscopic analyses (molecular formula of $C_{33}H_{32}N_{2}O_{10}$ and molecular weight of 617.21) and found to be identical to the kosinostatin, a quinocycline antibiotic which is known to be produced by Micromonspora sp. TP-A0468 (Igarashi et al., 2002) and to quinocycline B isolated from Streptomyces aureofaciens (Celmer et al., 1958). Although the antibiotic is known, the newly isolated strain was able to produce the antibiotic as a major product providing an important biotechnological downstream advantage.

• Journal of Power Electronics
• /
• v.19 no.3
• /
• pp.691-701
• /
• 2019

To solve the problems in the contact charging of inspection robots, a wireless charging system for inspection robots and a control strategy are introduced in this paper. Circuit models of a wireless power system with a compound compensation circuit and a three-phase Class-D resonant inverter are set up based on circuit theory. An output voltage control method based on the equal spread regulation of the phase difference between adjacent phases and the parameter correction method in the primary compound compensation circuit are proposed. The dynamic characteristics of the key parameters varying with the secondary coil position are obtained to further investigate the adaptive location scheme during the access and exit processes of moving robots. Combining the output voltage control method and the adaptive location scheme, a transition control strategy for the standby and operation modes of the wireless charging systems for inspection robots is put forward to realize the system characteristics including the low standby power in the standby mode and the high receiving power in the operation mode. Finally, experiments are designed and conducted to verify the correctness of the theoretical research.

• Current Optics and Photonics
• /
• v.6 no.6
• /
• pp.627-633
• /
• 2022

To realize uniform side pumping of solar lasers and improve their output power, a solar concentrating system based on off-axis parabolic mirrors is proposed. Four identical off-axis parabolic mirrors with focal length of 1,000 mm are toroidally arranged as the primary concentrator. Four two-dimensional compound parabolic concentrators (2D-CPCs) are designed as a secondary concentrator to further compress the focused spot induced by the parabolic mirrors, and the focused light is then homogenized by four rectangular diffusers and provides uniform pumping for a laser-crystal rod to achieve solar laser emission. Simulation results show that the solar power received by the laser rod, uniformity of the light spot, and output power of the solar laser are 7,872.7 W, 98%, and 351.8 W respectively. This uniform pumping configuration and concentrator design thus provide a new means for developing high-power side-pumped solid-state solar lasers.