• Journal of Ecology and Environment
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• v.38 no.3
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• pp.383-388
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• 2015

Reservoirs consist of two different environments, the littoral and the pelagic zone, and different fishing gear is commonly used in each zone-gill nets in the pelagic zone and electrofishing in the littoral zone. However, an active fishing gear, the cast net, is normally used instead of electrofishing for scientific studies in South Korea. In order to estimate cast net effectiveness for determining fish status in reservoirs, the study was conducted at 15 reservoirs with two different fishing gears: a cast net in the littoral zone and gill nets in the pelagic zone. When combining catches of both gears, species richness increased substantially compared to using one gear only. There was a size difference in fish caught by each net, and small fish were predominantly caught with the cast net due to its small mesh size (7 mm). The combined length of six species, used for length-weight relationship analysis, collected with the cast net was smaller than that collected with gill nets (independent t-test, P < 0.05). In this study, cast net sampling provided sufficient data for the littoral zone, but not enough to identify the overall fish assemblage in studied reservoirs. Utilization of only one gear can therefore lead to substantial underestimation of fish status, and a combination of both gears is recommended for determining more reliable estimates of fish status in reservoirs.

• Fashion & Textile Research Journal
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• v.9 no.4
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• pp.418-424
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• 2007

The purpose of this study is to propose a standard of converting 3D shape of men in twenties to 2D patterns. This can be a basis for scientific and automatic pattern making for high quality custom clothes. Firstly, representative 3D body shape of men was modeled. Then the 3D model was divided into 3 shells, front, side and back. Among them, the front shell was divided into 4 blocks by bust line and princess line. Secondly, curves are generated on each block according to matrix combination by grid method. Then triangles were developed into 2D pieces by reflecting the 3D curve length. The grid was arranged to maintain outer curve length. Next, the area of developed pieces and block were calculated and difference ratio between the block area and the developed pieces' area is calculated. Also, area difference ratio by the number of triangles is calculated. The difference ratio was represented as graphs and optimal section is selected by the shape of graphs. The optimal matrix was set considering connection with other blocks. Curves of torso upper front shell were regenerated by the optimal matrix and developed into pieces. We validated it's suitability by comparing difference ratio between the block area and the developed pieces' area of optimal section. The results showed that there was no significant difference between block area and the pieces' area developed by optimal matrix. The optimal matrix for 2D developing could be characterized as two types according to block's shape characteristics, one is affected by triangle number, the other is affected by number of raws more than columns. Through this study, both the 2D pattern developing from 3D body shape and 3D modeling from 2D pattern is possible, so it's standardization also possible.

• Journal of Society of Preventive Korean Medicine
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• v.15 no.3
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• pp.17-38
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• 2011

Objectives : This study aims to provide the fundamental information for future researches on combined medications of the oriental-western medicines or development of new Oriental medicine for hypertension. Methods : Every article related to hypertension was initially searched at journal web site, 'OASIS' and we finally analyzed 118 papers according to study types, kinds of herbal medicine, frequencies of herbal medicine, and results of researches. Results : Most studies were experiment researches which were composed of in vivo or in vitro. The formulas divided into 41 single and 99 complex prescriptions and total 218 medicinal materials were used in complex ones. The major effects of single prescriptions were decrease of the control of ACE activity and ANP concentration, while the effects of complex ones were various such as decrease of aldosteron concentration, decrease of epinephrine concentration, decrease of the heart rate, and decrease of dopamine concentration. Conclusions : More clinical studies based on scientific evidences should be done and the outcomes of this pilot study will contribute to development of Oriental medicines as substitute or combination for the western-hypertension remedies.

• Journal of Science and Technology Studies
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• v.1 no.1 s.1
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• pp.155-178
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• 2001

As is well known, logical positivists held the theory-independent of observation thesis(TIOT). On the other hand, the theories following the logical positivism typically represented by Hanson and Kuhn denied that there was a clear borderline between observation and theory, and held the theory-ladenness of observation thesis(TLOT). In order to mediate those theses I shall suggest a natural epistemic attitude (NEA) to the relation between theory and observation on the basis of the experimentalism. First, I discuss theories of Hanson and Kuhn as examples of views which profess TLOT. Then, I make a brief introduction of experimentalism and some critical discussions about TLOT follow from a point of the experimentalism: TLOT faces considerable counter-examples such as cases, 'observation precedes theory' and 'the combination of wrong theory and right observation'. I introduce a distinction between the guiding theory and the target theory in experimental situations and illustrate that TLOT loses its alleged power if we consider the distinction. Lastly, I suggest NEA, as conclusion of the paper, which can mediate among TIOT, TLOT, and experimentalism and takes a minimal ontology.

• Korean Journal of Clinical Pharmacy
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• v.28 no.1
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• pp.65-75
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• 2018

Objective: Over the last several years, immunotherapy has become one of the most promising therapeutic options for cancer. This study aims to summarize the updates on cancer immunotherapy focusing on immune checkpoint inhibitors, such as programmed cell death-1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitors, which have received attention as new anticancer therapeutic agents. Methods: A literature survey was carried out on PubMed to identify high-impact papers on cancer immunotherapy from 2010. The most recent data on clinical efficacy and safety have been included highlighting the response characteristics to recently approved immunotherapeutic agents. Results: In various cancers, immune checkpoints are a means for cancer cells to evade the immune system. Furthermore, CTLA-4 and PD-L1 can be overexpressed, allowing malignant cells to evade T-cells. Numerous clinical trials have been performed to seek appropriate indication of these products in various cancer types. Among them, the most conspicuous types are melanoma, non-small-cell lung cancer, and head and neck cancer. The approval of ipilimumab by Food and Drug Administration (FDA) commenced a new era of cancer immunotherapy. This was followed by the approval of nivolumab and pembrolizumab. Currently, combination therapies are being investigated for various cancer types. Conclusion: In this study, we reviewed recently reported scientific and clinical evidence for currently approved immune checkpoint inhibitors. Although these novel checkpoint inhibitors are ever evolving for cancer therapies, there exist limitations that need to be overcome, indicating the necessity for further studies aiming to improve their efficacy, toxicity, and cost.

• Journal of Periodontal and Implant Science
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• v.42 no.1
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• pp.25-29
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• 2012

Purpose: There has been no attempt to establish an objective implant surgical evaluation protocol to assess residents' surgical competence and improve their surgical outcomes. The present study presents a newly developed assessment and rating system and simulation model that can assist the teaching staffs to evaluate the surgical events and surgical skills of residents objectively. Methods: Articles published in peer-reviewed English journals were selected using several scientific databases and subsequently reviewed regarding surgical competence and assessment tools. Particularly, medical journals reporting rating and evaluation protocols for various types of medical surgeries were thoroughly analyzed. Based on these studies, an implant surgical technique assessment and rating system (iSTAR) has been developed. Also, a specialized dental typodont was developed for the valid and reliable assessment of surgery. Results: The iSTAR consists of two parts including surgical information and task-specific checklists. Specialized simulation model was subsequently produced and can be used in combination with iSTAR. Conclusions: The assessment and rating system provided may serve as a reference guide for teaching staffs to evaluate the residents' implant surgical techniques.

• KIEAE Journal
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• v.2 no.4
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• pp.41-47
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• 2002

East Asian explain the changes of substance happened on earth and those of human life with the conceptual frame of "Gi-ki"(地氣; earth vital energy) and organize them by the system of "Feng-shui(風水) theory. The core of Feng-shui theory is reading the expression of the nature and feeling the Gi-ki from the expression. One of the properties of the earth is that the earth has a magnetic field associated with it- the Geomagnetic field. The geomagnetic field is produced by a combination of the effects of electric currents in the earth's liquid core, the magnetization of crustal rocks, external electric current systems that surround the earth and currents induced in the outer layers of the earth by magnetic field variations. The sameness of logic between Feng-shui and geopathic zones is that both are concerned with the discrimination of site and the energy of places, in other words both disciplines are concerned with how the environment can influence people. In this context the operation of Gj-ki can be related with the effect caused by geomagnetic field on site. In this study Jongmyo(宗廟), one of the representative traditional architecture in Korea is selected because the site selection and building layout follows Feng-shui faithfully according to Taejo silok (太祖實錄, Annals of King Taejo). Observing the landforms surrounding Jongmyo, Jongmyo is apparently located in auspicious places named Gumge Poranhyoeng(金鷄抱卵形, a Feng-shui landscape of golden hen sitting on eggs). The geomagnetic investigation of Jongmyo shows that the geomagnetic values of Toekan(the space near Hyeol) are relatively high and uniform and those of Sangweoldae and Haweoldae are decreased in accordance with the distance. The result shows that there is possibility that Feng-shui has scientific basis related with geomagnetic field. Feng-shui theory can suggest a direction for designing the sustainable building for living with nature.

• Journal of the Korea Furniture Society
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• v.27 no.3
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• pp.175-184
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• 2016

Art Furniture is a terminology of creative and developed activity related Art in the field of furniture design. In a broad sense, the extent of Art furniture reaches from humanities to technology because Art includes them. Due to Postmodernism, designers who were involving Art furniture started to fuse various studies including high technology to achieve their own goals. To illustrate with the characteristic of high technology, I compare between low technology and high technology. Even though high technology are used both commercial furniture and Art furniture, the latter has been utilized high technology in a more creative and experimental way to develop experimental furniture design. In contrast, in order to earn economic profit, there is no unnecessary risk for commercial furniture. Considering information revolution which is deeply related with high technology, Art furniture designers could get information easily about other fields and make multiple connections of different kinds of people and markets. As a result, a combination between Art furniture and high technology has distinctive features. At first, high technology was applied to craft among Dutch furniture designers. After that, designers began to lay out the method of high technology and pushed the boundary of Art furniture thanks to experts and scientists. In addition, there was a designer who have conducted a series of research as a scientist adopting scientific methodology. In doing so, Joris Laarman could obtain a revolutionized work which could contribute society. In conclusion, combining Art furniture and high technology leads the definition of design from deciding physical shapes to directing and organizing processes.

• Journal of Society of Preventive Korean Medicine
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• v.1 no.1
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• pp.105-117
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• 1997

The result of this paper runs as follows: 1. The theory of preclinic phase (=mibyung) was scientifically completed as one basic philosophy in "NAEKYUNG(內經)" and on influenced in the coming generations. Two principles for mibyung is to grow good energy and to avoid etiological cause. 2. So far oriental medicine has responded to already diseases, while to recognize the importance of mibyung is to convert it into preventive medicine which study and improve health. In spite of the opinion that no disease is health and no health is disease, the contrite of medical approch by the relative importance is necessary by understanding the steps of mibyung between health and disease with subdividing the steps of the occurance therefore, the scope of oriental medicine may be recognized from every disease to mibyung, that is, health. 3. Diagnosing and treating in the step of mibyung has more important meaning than suffering step because the checkup of mibyung means early examination and treatment. Mibyung can make an opportunity that improve scientific contradiction and defect of oriental medicine. However, scince the theory and practice lack the arrangement and study, much exertion and discussion is necessary.4. The diagnosis and cure in mibyung doesn't have many methods for treating, its index and standard isn't nified, and related theory is of small quantity. But the most prominent means of solution. with combination with other sciences and through the convertion into modem clinical examination, is to accomplish moderization, objectivity and indexation, etc. 5. The representive mibyungs are a hereditary disease, immune lack, mutation, early tumor, incubation of hepatitis and each infectious diseases, stress, etc. Since every science is the product of the times, it has the historical limits. As the times develop, the desire for good health is growing. Therefore we should consider above request in this times.

• Journal of the East Asian Society of Dietary Life
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• v.18 no.1
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• pp.104-110
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• 2008

This research was designed and implemented to evaluate how the composition of yaksuncha can affect the health of individuals suffering from diet-related diseases such as obesity and hyperlipidemia by prescribing Yaksun as a nutritional supplement with daily meals. The yaksunucha was prepared as Koekac, Sansa, Heshouwu and Woolong tea and the tea's effects on serum lipids and oxidative stress were evaluated by clinical procedures. The yaksuncha significantly increased HDL-cholesterol and decrease of LDL-cholesterol concentrations in serum. It also had significant effects on decreasing oxidative stress and homocystein levels. The physical characteristics of the yaksunucha were also examined, showing. Brix, pH and titratable acidity values of 1.4, 5.50 and 0.05% respectively. It is thought that scientific and objective evaluations were completed on the components of the yaksuncha prescription. Thus one can concluded that the components could be applied not only in the form of tea, but also various food. The data derived from this study provides basic information that will aid in the application of oriental medicinal resources to other foods as well as facilitate the study of medicinal herbs within the field of functional food research, which already draws sizable attention worldwide.