• Title/Summary/Keyword: science and arts

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DERIVED FUNCTOR COHOMOLOGY GROUPS WITH YONEDA PRODUCT

  • Husain, Hafiz Syed;Sultana, Mariam
    • The Pure and Applied Mathematics
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    • v.28 no.2
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    • pp.187-198
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    • 2021
  • This work presents an exposition of both the internal structure of derived category of an abelian category D*(𝓐) and its contribution in solving problems, particularly in algebraic geometry. Calculation of some morphisms will be presented between objects in D*(𝓐) as elements in appropriate cohomology groups along with their compositions with the help of Yoneda construction under the assumption that the homological dimension of D*(𝓐) is greater than or equal to 2. These computational settings will then be considered under sheaf cohomological context with a particular case from projective geometry.

Psychological And Pedagogical Aspects Of Implementation Of Innovation In The Modern Educational Process

  • Hordieiev, Volodymyr;Shcherbakova, Nadiia;Syryatska, Tetyana;Popov, Yuriy;Сhernyshchuk, Yulia;Pavlenko, Inna
    • International Journal of Computer Science & Network Security
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    • v.22 no.11
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    • pp.19-24
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    • 2022
  • The article determines that, in the preservation of cultural heritage, lifestyle, an important role is played by the subjects' high assessment of the probability of achieving the result they need through the implementation of traditional models, ways of interaction. If dissatisfaction with the results of interaction is great, but there are no necessary conditions for a phased resolution of contradictions, for changing, developing interpersonal relations within the framework of the existing system, interaction becomes more difficult. It has been determined that the presence of effective models that show the possibility of meeting the requirements for the psyche of a variety of individuals from the side of activity, activating an extended search for mutually acceptable ways to success, depends on the development of the personality and its social relations, the success of interaction between people, socially psychological climate in the team.

Association of an LMP2 Polymorphism with Acute Myeloid Leukemia and Multiple Myeloma

  • Ozbas-Gerceker, Filiz;Bozman, Nazli;Kok, Selcuk;Pehlivan, Mustafa;Yilmaz, Mehmet;Pehlivan, Sacide;Oguzkan-Balci, Sibel
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6399-6402
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    • 2013
  • Hematological malignancies (HM) are a group of neoplasms derived from the cells of the bone marrow and lymphatic system. Genetic factors leading to susceptibility to HM have been investigated for years but little is known yet. Low molecular weight polypeptide (LMP) 2 and LMP7 genes are important subunits of the immunoproteasome and play significant role in antigen presentation. The polymorphisms of LMP genes have been reported to be risk factors for various types of diseases. The aim of this study was to investigate the association of LMP2 and LMP7 polymorphisms with the occurrence of particular types of HM. A total of 132 patients with HM and 130 control subjects were investigated. No significant difference was obtained in the distribution of genotype and allele frequencies of LMP7 gene in HM patients and the control group. On the other hand, the prevalence of LMP2-AA genotype was found to be higher in acute myeolid leukemia (AML) patients while it was significantly lower in multiple myeloma (MM) cases than in the control subjects. Our results suggested that LMP7 could not be a risk factor for susceptibility to HM, whereas LMP2 polymorphisms could play a role in the development of AML and MM.

Association of TAP1 and TAP2 Gene Polymorphisms with Hematological Malignancies

  • Ozbas-Gerceker, Filiz;Bozman, Nazli;Gezici, Sevgi;Pehlivan, Mustafa;Yilmaz, Mehmet;Pehlivan, Sacide;Oguzkan-Balci, Sibel
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.5213-5217
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    • 2013
  • Transporter associated with antigen presenting (TAP) 1 and TAP2 genes are localized in the major histocompatability complex (MHC) class II region and form a heterodimer playing a key role in endogenous pathways for antigen presentation. Defects of these genes have been reported to be common in different types of cancer. Polymorphisms identified in these loci have also been investigated and reported to be associated with several autoimmune disorders, viral infections and neoplasms. In the present study, for the first time, the allele and genotype frequencies of TAP1-333, TAP2-565, TAP2-651 and TAP2-665 were determined in patients with hematological malignancies (HM) using a PCR-RFLP method and compared with the frequencies in the control group. Our results suggested an association of TAP1-333 polymorphism with multiple myeloma-MM and TAP2-565 polymorphism with chronic lymphoid leukemia-CLL. In addition, it could be concluded that the TAP2-665 GG genotype might be a risk factor for all types of hematological malignancies included in this study.

The nano scale buckling properties of isolated protein microtubules based on modified strain gradient theory and a new single variable trigonometric beam theory

  • Alwabli, Afaf S.;Kaci, Abdelhakim;Bellifa, Hichem;Bousahla, Abdelmoumen Anis;Tounsi, Abdelouahed;Alzahrani, Dhafer A.;Abulfaraj, Aala A.;Bourada, Fouad;Benrahou, Kouider Halim;Tounsi, Abdeldjebbar;Mahmoud, S.R.;Hussain, Muzamal
    • Advances in nano research
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    • v.10 no.1
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    • pp.15-24
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    • 2021
  • Microtubules (MTs) are the main part of the cytoskeleton in living eukaryotic cells. In this article, a mechanical model of MT buckling, considering the modified strain gradient theory, is analytically examined. The MT is assumed as a cylindrical beam and a new single variable trigonometric beam theory is developed in conjunction with a modified strain gradient model. The main benefit of the present formulation is shown in its new kinematic where we found only one unknown as the Euler-Bernoulli beam model, which is even less than the Timoshenko beam model. The governing equations are deduced by considering virtual work principle. The effectiveness of the present method is checked by comparing the obtained results with those reported by other higher shear deformation beam theory involving a higher number of unknowns. It is shown that microstructure-dependent response is more important when material length scale parameters are closer to the outer diameter of MTs. Also, it can be confirmed that influences of shear deformation become more considerable for smaller shear modulus and aspect ratios.

Oxidative Stress in Vivax Malaria

  • Bilgin, Ramazan;Yalcin, Mustafa S.;Yucebilgic, Guzide;Koltas, Ismail S.;Yazar, Suleyman
    • Parasites, Hosts and Diseases
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    • v.50 no.4
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    • pp.375-377
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    • 2012
  • Malaria is still a leading cause of morbidity and mortality. The increase in lipid peroxidation reported in malaria infection and antioxidant status may be a useful marker of oxidative stress during malaria infection. The aim of this study was to investigate the role of antioxidant enzymes against toxic reactive oxygen species in patients infected with Plasmodium vivax and healthy controls. Malondialdehyde levels, superoxide dismutase, and glutathione peroxidase activities were determined in 91 P. vivax patients and compared with 52 controls. Malondialdehyde levels, superoxide dismutase, and glutathione peroxidase activities were $8.07{\pm}2.29$ nM/ml, $2.69{\pm}0.33$ U/ml, and $49.6{\pm}3.2$ U/g Hb in the patient group and $2.72{\pm}0.50$ nM/ml, $3.71{\pm}0.47$ U/ml, and $62.3{\pm}4.3$ U/g Hb in the control group, respectively. Malondialdehyde levels were found statistically significant in patients with vivax malaria higher than in healthy controls (P<0.001). On the other hand, superoxide dismutase and glutathione peroxidase activities were found to be significantly lower in vivax malaria patients than in controls (P<0.05). There was an increase in oxidative stress in vivax malaria. The results suggested that antioxidant defense mechanisms may play an important role in the pathogenesis of P. vivax.

Creating Innovative Packaging and Logo Design for the Golden Banana Product to Modernize and Enhance Distribution

  • Wat PLOYSRI;Krairop CHAREONSOPA
    • Journal of Distribution Science
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    • v.22 no.8
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    • pp.55-63
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    • 2024
  • Purpose: This study focuses on the golden banana (Kluai Hom Thong) from the Ban Khok Banana Community Enterprise Group in Sang Khom District, Udon Thani Province, Thailand. Despite its potential as an export crop and minimal disease or insect management issues, the group's products struggled to reach international markets due to lack of marketing opportunities, distribution channels, and proper packaging. The research aims to analyze and develop packaging and logos to test market potential for the group's products. Research design, data and methodology: Data was collected through questionnaires developed in conjunction with three printing and packaging design experts. Market testing involved 100 randomly sampled consumers of the group's products. Results: The new packaging design was perceived as more international, modern, and suitable as a souvenir for adults. Conclusions: Integrating ethnic elements and local materials into packaging design can enhance product appeal. For example, creating cloth bags from fabric scraps for carrying local woven products can impress consumers. This approach could help overcome market barriers and improve prospects for golden banana products in international markets while maintaining the intact ecosystem and environment of the production area. The study highlights the importance of effective packaging and branding in addressing market access challenges for local agricultural enterprises, potentially opening new opportunities for community-based businesses.

Validity of giftedness based on clusters (영재성 요인의 분야별 타당화 연구)

  • 심재영;김언주
    • Journal of Gifted/Talented Education
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    • v.13 no.2
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    • pp.1-22
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    • 2003
  • The purpose of the present study is to examine implicit capabilities of giftedness by Korean adults and to validate the features of giftedness by asking the gifted students in science, liberal arts, and ordinary. Existing researches have problems as follows; they will make a high error when we distinguish gifted students who applied to various changeable conditions because they only use total score without their sub-attributes and because they designed from the viewpoint of age. And they are difficult and complex for students to understand. This study is composed of two parts, Study 1 and Study 2. In study 1, we examined and analyzed the Korean's implicit concept of giftedness to 328 adults. In Study 2, the features of the Koreans' implicit concept for giftedness were validated to 1154 students in science, liberal arts, and ordinary. Giftedness features and patterns were identified by factor analysis. In the last place, we suggested the distribution of T-value scale for each feature of giftedness.

Understanding Information Sharing Among Scientists Through a Professional Online Community: Analyses on Interaction Patterns and Contents

  • Shin, Eun-Ja;Lee, Guiohk;Choi, Heeyoon
    • Journal of Information Science Theory and Practice
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    • v.5 no.4
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    • pp.26-38
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    • 2017
  • Even through many professional organizations increasingly use Q&A sites in their online communities for information sharing, there are few studies which examine what is really going on in the Q&A activities in professional online communities (POC). This study aims to examine the interaction patterns and contents posted in the Q&A site of a POC, KOSEN, a science and technology online community in South Korea, focusing on how actively scientific information and knowledge are shared. The interaction patterns among the participants were identified through social network analysis (SNA) and the contents in the Q&As were examined by content analysis. The results show that the overall network indicated a moderate level of participation and connection and answerers especially tended to be active. Also, there are different interaction patterns depending on academic fields. Relatively few participants were posting leaders who seemed to steer the overall interactions. Furthermore, some content related to manipulation and explanation for experiments, which are in urgent need, seem to be posted in the sites more frequently with more amounts. Combining both SNA and content analysis, this study demonstrated how actively information and knowledge is shared and what types of contents are exchanged. The findings have practical implications for POC managers and practitioners.