• Title/Summary/Keyword: scale-model

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Cost-Utility Analysis of Pegfilgrastim and Pegteograstim in Patients with Breast Cancer using Doxorubicin and Cyclophosphamide (Doxorubicin과 Cyclophosphamide를 투여받는 유방암 환자에서 Pegfilgrastim과 Pegteograstim의 비용-효용 분석)

  • Kwon, Su Ji;Geum, Min Jung;Kim, Jae Song;Son, Eun Sun;Kwon, Kyeng Hee
    • Journal of Korean Society of Health-System Pharmacists
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    • v.35 no.4
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    • pp.409-417
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    • 2018
  • Background : Febrile neutropenia (FN) is one of the side effects in the patients treated with chemotherapy, and the patients who have FN generally need immediate treatment with extended-spectrum antibiotics and hospitalization. Pegfilgrastim and pegteograstim, which are used for the prevention of FN as a granulocyte-colony stimulating factor (G-CSF), have been granted insurance coverage in the Republic of Korea for certain breast cancer patients using doxorubicin and cyclophosphamide (AC) from September 2016. Methods : The data of the patients with breast cancer using AC regimen and G-CSF were collected retrospectively. This study involves cost-utility analysis of pegfilgrastim and pegteograstim. In this study, we constructed a simple decision tree model for short-term observation and calculated quality-adjusted life year (QALY) and the direct medical costs from the medical provider's perspective. Results : From September 2016 to May 2017, 15 patients were treated with pegfilgrastim and 15 patients were treated with pegteograstim. As a result of dividing the average cost by QALY for each treatment group, it was observed that pegfilgrastim and pegteograstim were consumed 24,923,384 won and 22,808,336 won per 1QALY, respectively. Consequently, incremental cost effectiveness ratio (ICER) showed 2,115,048 won more per pegfilgrastim than pegteograstim per 1QALY, and the cost per 1QALY of both the drugs was lower than 30,500,000 won; the Koreans were willing to pay this amount. Conclusions : This study suggests that pegfilgrastim and pegteograstim can be used to improve the quality of life of breast cancer patients undergoing AC therapy. Among the two drugs, pegteograstim seems to be more cost-effective. However, since this study was conducted as a retrospective observation method on a small scale, it is associated with many limitations. Therefore, a long-term prospective cohort study is needed to supplement the present findings.

Validity and reliability of the Korean version of the Quality of Recovery-40 questionnaire

  • Lee, Jun Ho;Kim, Deokkyu;Seo, Donghak;Son, Ji-seon;Kim, Dong-Chan
    • Korean Journal of Anesthesiology
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    • v.71 no.6
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    • pp.467-475
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    • 2018
  • Background: The Quality of Recovery-40 (QoR-40) is a widely-used, self-rated, and self-completed questionnaire for postoperative patients. The questionnaire is intended to elicit information from each patient regarding the quality of recovery during the postoperative period. It is noteworthy, however, that an official Korean version of the QoR-40 (QoR-40K) has not been established. The purpose of this study was to develop the QoR-40K by translation and cultural adaptation process and to evaluate the validity and reliability of the QoR-40K. Methods: After pre-authorization from the original author of the QoR-40, the translation procedure was established and carried out based upon Beaton's recommendation to create a QoR-40K model comparable to the original English QoR-40. Two hundred surgical patients were enrolled, and each completed the questionnaire during the preoperative period, on the third day, and 1 month after surgery. The QoR-40K was compared with the visual analogue scale (VAS) and another health-related questionnaire, the Short-form Health Survery-36 (SF-36). The method of validation for QoR-40K included test-retest reliability, internal consistency, and level of responsiveness. Results: Spearman's correlation coefficient for test-retest reliability was 0.895 (P < 0.001), and Cronbach's alpha of the global QoR-40K on the third day after surgery was 0.956. A positive correlation was obtained between the QoR-40K and the mental component summary of SF-36 (${\rho}=0.474$, P < 0.001), and a negative correlation was observed between QoR-40K and VAS (${\rho}=-0.341$, P < 0.001). The standardized responsive mean of the total QoR-40K was 0.71. Conclusions: The QoR-40K was found to be as acceptable and reliable as the original English QoR-40 for Korean patients after surgery, despite the apparent differences in the respective patients' cultural backgrounds.

Social Psychological Characteristics of Juvenile Offenders (소년범죄자의 사회심리적 성격특성)

  • Koh, Jae-Won
    • The Journal of the Korea Contents Association
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    • v.21 no.10
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    • pp.702-711
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    • 2021
  • In order to examine the type of PAI profile for criminally charged juvenile offenders, the study sought to find out personality types and behavioral characteristics of 251 juvenile offenders and 173 ordinary adolescents from 2018-2020. Looking at the overall profiles of juvenile offenders and ordinary adolescents, we found differences in Infrequency(INF), Mania(MAN), Antisocial Features(ANT), Alcohol problems(ALC), Drug problems(DRG), Aggression (AGG), and Dominance(DOM) and Warmth(WRM). Based on these results, we perform clustering as factors Antisocial features(ANT), Aggression(AGG), and Dominance (DOM) with an average difference of more than five points. It was classified as Cluster 1 with a high percentage of adolescents and Cluster 2 with a high percentage of juvenile offenders, and Cluster 1 was named as a defense group because it showed a similar model to the profile of ordinary adolescents. The profile type of cluster 2 was named externalization, which can be represented as an externalization group. The results were similar to previous studies, and the profile type of juvenile offenders has higher overall clinical scale than that of ordinary adolescents, indicating behavioral problems. Continued research on juvenile offenders could lead to understanding of youth as well as juvenile offenders.

An Application and Educational Outcomes of e-PBL (e-Project-based Learning) to University Forest Education (대학 산림교육의 웹기반 프로젝트 학습법(e-PBL) 적용 사례와 학습성과)

  • Lee, Songhee;Lee, Jaeeun;Kang, Hoduck;Yoon, Tae Kyung
    • Journal of Korean Society of Forest Science
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    • v.110 no.2
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    • pp.266-279
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    • 2021
  • This study applied the e-PBL (e-Project-based learning) method for "Urban Forest Management" courses in the Department of Forest Science at S University to progress in university forest education. e-PBL effectively motivates self-directed learning, problem-solving, communication skills, and learners' responsibility by enabling them to choose, design, and perform their projects. Due to the COVID-19 pandemic in 2020, learners were encouraged to use online media to carry out projects and submit presentations for the campus forest. Learners' educational effects were subsequently investigated through a five-point Likert scale. This study discovered a positive effect on learners' motivation and interest (4.17) through e-PBL. Learners responded that e-PBL also helped their understanding regarding the subject (4.17). In addition, this study provided evidence that the e-PBL method was helpful in problem-solving (4.25), communication (4.33), and decision-making skills (4.21). According to learners' responses, there are positive indications that learners were satisfied with e-PBL. Learners responded that interactions and communications with team members could improve their understanding of the subject. Hence, there is scope for improving an efficient and successful e-PBL model suitable for university forest education by providing more efficient instructional time management, e-PBL method guidelines, and institutional support.

A vision-based system for long-distance remote monitoring of dynamic displacement: experimental verification on a supertall structure

  • Ni, Yi-Qing;Wang, You-Wu;Liao, Wei-Yang;Chen, Wei-Huan
    • Smart Structures and Systems
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    • v.24 no.6
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    • pp.769-781
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    • 2019
  • Dynamic displacement response of civil structures is an important index for in-construction and in-service structural condition assessment. However, accurately measuring the displacement of large-scale civil structures such as high-rise buildings still remains as a challenging task. In order to cope with this problem, a vision-based system with the use of industrial digital camera and image processing has been developed for long-distance, remote, and real-time monitoring of dynamic displacement of supertall structures. Instead of acquiring image signals, the proposed system traces only the coordinates of the target points, therefore enabling real-time monitoring and display of displacement responses in a relatively high sampling rate. This study addresses the in-situ experimental verification of the developed vision-based system on the Canton Tower of 600 m high. To facilitate the verification, a GPS system is used to calibrate/verify the structural displacement responses measured by the vision-based system. Meanwhile, an accelerometer deployed in the vicinity of the target point also provides frequency-domain information for comparison. Special attention has been given on understanding the influence of the surrounding light on the monitoring results. For this purpose, the experimental tests are conducted in daytime and nighttime through placing the vision-based system outside the tower (in a brilliant environment) and inside the tower (in a dark environment), respectively. The results indicate that the displacement response time histories monitored by the vision-based system not only match well with those acquired by the GPS receiver, but also have higher fidelity and are less noise-corrupted. In addition, the low-order modal frequencies of the building identified with use of the data obtained from the vision-based system are all in good agreement with those obtained from the accelerometer, the GPS receiver and an elaborate finite element model. Especially, the vision-based system placed at the bottom of the enclosed elevator shaft offers better monitoring data compared with the system placed outside the tower. Based on a wavelet filtering technique, the displacement response time histories obtained by the vision-based system are easily decomposed into two parts: a quasi-static ingredient primarily resulting from temperature variation and a dynamic component mainly caused by fluctuating wind load.

Accuracy Analysis for Slope Movement Characterization by comparing the Data from Real-time Measurement Device and 3D Model Value with Drone based Photogrammetry (도로비탈면 상시계측 실측치와 드론 사진측량에 의한 3D 모델값의 정확도 비교분석)

  • CHO, Han-Kwang;CHANG, Ki-Tae;HONG, Seong-Jin;HONG, Goo-Pyo;KIM, Sang-Hwan;KWON, Se-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.4
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    • pp.234-252
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    • 2020
  • This paper is to verify the effectiveness of 'Hybrid Disaster Management Strategy' that integrates 'RTM(Real-time Monitoring) based On-line' and 'UAV based Off-line' system. For landslide prone area where sensors were installed, the conventional way of risk management so far has entirely relied on RTM data collected from the field through the instrumentation devices. But it's not enough due to the limitation of'Pin-point sensor'which tend to provide with only the localized information where sensors have stayed fixed. It lacks, therefore, the whole picture to be grasped. In this paper, utilizing 'Digital Photogrammetry Software Pix4D', the possibility of inference for the deformation of ungauged area has been reviewed. For this purpose, actual measurement data from RTM were compared with the estimated value from 3D point cloud outcome by UAV, and the consequent results has shown very accurate in terms of RMSE.

A Study on Traditional Darangyi-Rice Terrace as Design Factors of Agricultural Landscape (농업경관의 디자인적 요소인 전통다랑논 조사연구)

  • Son, Ho-Gi;Kim, Sang-Bum;Kim, Eun-Ja;Rhee, Sang-Young
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.29 no.1
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    • pp.157-165
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    • 2011
  • This study is to be used as a fundamental material of rural amenity resources researches, such as excavating, establishing and modifying national agricultural landscape resources, so as to efficiently manage them. It is carried out with targeting traditional Darangyi-Rice terrace which has design factors of agricultural landscape resources. We have set up the standard range with practicable similar standard(Marginal Farmland and Less Favored Areas and etc), those of Japan, and the results of analyzing the characteristics of Darangyi-Rice terrace already known. As a result of the field investigation, it has been revealed that a great deal of Darangyi-Rice terrace are being used for not corresponding purposes, or damaged and disappeared. For preserving and well-managing Darangyi-Rice terrace as a rural landscape resource which has rural design factors, it should be advanced detailed and accurate studies on present conditions and changes of Darangyi-Rice terrace, with researches on significances, values, utilities and economical efficiency of Darangyi-Rice terrace by regions. In addition, we utilized various spatial imagery data in the researching process. Consequently, it is concluded that if high resolution imagery data is used, it can establish rather minute and accurate large-scale DB, and monitor elaborate changes as well. It is therefore thought that its application can be higher as actualizing DB hereafter.

Analysis of multicultural education research trends in Korea (한국 다문화교육의 연구동향 분석 : Bennett이론에 근거하여)

  • Chang, Insil;Cha, Kyung-Hee
    • (The)Korea Educational Review
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    • v.18 no.1
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    • pp.283-302
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    • 2012
  • Multicultural families have literally started to settle in Korea since the late 1980s, yet it was not until the middle of 2000 that multicultural education was actually arisen with its full-scale discussions. Domestic studies on multicultural education have now remarkably been conducted in various aspects and points of views, but with no certain level of collective and comprehensive analysis yet. To seek Korean way of finding out appropriate solutions to its multicultural society, a contemporary major trend in the world, it is necessary to keep developing the theory and practice in Korean multicultural education with constructive criticism over the development. In this thesis, the research trends and characteristics of Korea multicultural education are analyzed according to the three categories: the times of the study, the subjects of the study, and the themes of the study. The analysis of the study themes, in particular, is done based on the four core areas presented by Bennett: equity pedagogy, curriculum reform, multicultural competence, and societal equity. Furthermore, the analysis includes the five additional Korean sub-categories, which are also acquired in the process of our analysis of the thesis: multiculturalism, global multicultural education, counselling research, measurement development, and citizenship education, added to Bennett's three sub-ones of each area. Overall, based on the analysis data, this study investigates further improvements and subsequent research themes in the following researches on Korean multicultural education.

Effect of Community-Based 'Goal-Achieving Program' in Patient with Late-Life Depression : Preliminary Study (노인성 우울증 환자에서 지역사회 기반 '목표달성 프로그램'의 효용성 : 예비 연구)

  • Kang, Gyu Ha;Chang, Ki Jung;Lim, Hyun Kook;Han, Jin joo;Lee, Eun Hee;Roh, Hyun Woong;Noh, Jai Sung;Chung, Young Ki;Lim, Ki Young;Hong, Chang Hyung;Son, Sang Joon
    • Journal of Korean geriatric psychiatry
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    • v.21 no.1
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    • pp.35-40
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    • 2017
  • Objective : This study aimed to investigate the effect of community-based Goal-Achieving program in geriatric depressive symptoms preliminarily. Methods : We obtained data from elderly Korean subjects with major depressive disorder (n=51) aged 60 years or older at baseline, taking case management from community mental health center. Subjects were randomly assigned to intervention group (n=24) and control group (n=27). We investigated depressive symptoms through Short Form Geriatric Depression Scale-Korean version (SGDS-K) at baseline and every month for 3 months to all subjects. We tested interaction between group and time in SGDS-K score to evaluate the effect of program. And post hoc test examined between group differences of SGDS-K at each time points. Results : In quadratic linear mixed effects model analysis, interaction between group and time was statistically significant (Total SGDS-K score : coefficient=0.29, p<0.001 ; SGDS-K dysphoria subscale : 0.18, p<0.001 ; SGDS-K hopelessness subscale : 0.05, p=0.089 ; SGDS-K cognitive impairment subscale : 0.06, p=0.003). And significant between group difference was shown in post hoc test at time points of third month (SGDS-K score of control group : SGDS-K score of intervention group=$10.74{\pm}3.482$ : $7.25{\pm}4.475$, p=0.0184). Conclusion : These results may suggest that 'Community-based the Goal-Achieving program' has efficacy in reducing geriatric depressive symptoms.

The Effect of Different Counselors on Treatment Outcome of Tinnitus Retraining Therapy (상담자 요소가 이명재훈련치료의 효과에 미치는 영향)

  • Kim, Woo Jin;Kong, Ji Sun;Park, So Young;Jung, Ki Hwan;Kim, Rae Hyung;Yeo, Sang Won;Park, Shi Nae
    • Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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    • v.60 no.5
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    • pp.209-214
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    • 2017
  • Background and Objectives Tinnitus retraining therapy (TRT) is one of the most effective treatment modalities of tinnitus based on the neurophysiological model proposed by Jastreboff and Hazell. This study was performed to evaluate the effect of counselor factor on treatment outcomes of TRT. Subjects and Method The total of 78 patients who had TRT from three different counselors in a tinnitus clinic of tertiary referral center from Jan 2015 to Dec 2015 were included in this study. Their medical records were retrospectively reviewed to evaluate the therapeutic response to TRT. Results Among 78 patients who were followed-up for more than 6 months, 47, 20, and 11 patients were treated by counselors A, B, C (all ENT specialists), respectively. Counselor A had 15-year-experience of TRT counseling, whereas counselor B and C were well trained but beginners of TRT counseling. Initial clinical characteristics including Tinnitus Handicap Inventory (THI) and tinnitus Visual Analogue Scale (VAS) scores of the patients among three groups were not significantly different. Treatment responses evaluated via THI and most of the tinnitus VAS scores after at least 6 months after TRT were significantly improved in all three groups (p<0.05) with no significant difference between the senior (A) and junior (B, C) group. Conclusion TRT seems to be an effective treatment modality of tinnitus even in this short term follow-up study. Treatment outcomes of TRT may not depend on the counselors once they are well trained and follow the same protocol.