• 제목/요약/키워드: scale-model

검색결과 8,440건 처리시간 0.037초

Design, Fabrication, and Application of a Microfluidic Device for Investigating Physical Stress-Induced Behavior in Yeast and Microalgae

  • Oh, Soojung;Kim, Jangho;Ryu, Hyun Ryul;Lim, Ki-Taek;Chung, Jong Hoon;Jeon, Noo Li
    • Journal of Biosystems Engineering
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    • 제39권3호
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    • pp.244-252
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    • 2014
  • Purpose: The development of an efficient in vitro cell culture device to process various cells would represent a major milestone in biological science and engineering. However, the current conventional macro-scale in vitro cell culture platforms are limited in their capacity for detailed analysis and determination of cellular behavior in complex environments. This paper describes a microfluidic-based culture device that allows accurate control of parameters of physical cues such as pressure. Methods: A microfluidic device, as a model microbioreactor, was designed and fabricated to culture Saccharomyces cerevisiae and Chlamydomonas reinhardtii under various conditions of physical pressure stimulus. This device was compatible with live-cell imaging and allowed quantitative analysis of physical cue-induced behavior in yeast and microalgae. Results: A simple microfluidic-based in vitro cell culture device containing a cell culture channel and an air channel was developed to investigate physical pressure stress-induced behavior in yeasts and microalgae. The shapes of Saccharomyces cerevisiae and Chlamydomonas reinhardtii could be controlled under compressive stress. The lipid production by Chlamydomonas reinhardtii was significantly enhanced by compressive stress in the microfluidic device when compared to cells cultured without compressive stress. Conclusions: This microfluidic-based in vitro cell culture device can be used as a tool for quantitative analysis of cellular behavior under complex physical and chemical conditions.

An Empirical Analysis on Macro-economic Effects of the Proposed Reduction of Legal Working Hours in Korea (법정근로시간 단축의 거시경제 효과 분석)

  • Nam, Sung-il
    • Journal of Labour Economics
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    • 제25권2호
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    • pp.33-78
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    • 2002
  • This study analyzes effects of the proposed reduction of legal working hours in Korea in which base wage is unchanged with working hours reduction. The theoretical analysis shows that a reduction of legal working hours would result in less than equal size reduction of actual working hours, and increase in wages. On the other hand, the effects on employment is ambiguous depending on the substitution effect and scale effect. An empirical analysis based on macro-economic model simulation supports the theoretical conjecture. It has been found that with the reduction of legal working hours, real wages and consumption increase while actual working hours decreases about half of the legal hours reduction. In addition, the immediate and outright imposition of legal hours reduction on all sectors of the economy is found to create a cost push inflation and reduce GDP, investment, and employment. This negative effects are lessened as the reduction of legal hours is gradually made and/or some measures to absorb the cost shock such as abolition of paid monthly leave are employed together.

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Quality Management on the 4th Industrial Revolution (4차 산업혁명시대의 품질경영)

  • Chong, Hye Ran;Hong, Sung Hoon;Lee, Min Koo;Kwon, Hyuck Moo
    • Journal of Korean Society for Quality Management
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    • 제45권4호
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    • pp.629-648
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    • 2017
  • Purpose: The world faces a great turning point fundamentally rebuilding the future, and human lives, by embracing the 4th industrial revolution era. This paper aims to seek new and various business models in the 4th industrial revolution era, and to examine the evolution of quality management in the changing of the industrial ecosystem. Methods: This paper examines the various strategies of approaching the 4th industrial revolution in Germany, the USA, Japan, China, and Korea. This paper also draws detailed items by classifying the six major items of Malcolm Baldridge into large, medium, and small scale classifications, researches items from the technical perspective by applied fields, and the four major factor perspectives of quality management, as well as analyzes the relevant items in a multidimensional method. After a questionnaire survey targeting 200 quality experts was conducted, the important quality management factors were selected by applying the Analytic Hierarchy Process (AHP) method. Results: The importance of the general criteria was analyzed in the order of customers, MAKM (measurement, analysis, and knowledge management), workforce, strategy, operations, and leadership. As for the importance analysis results of the secondary subcriteria, the following items are highly analyzed: senior leadership, searching business model's innovation opportunity, customer satisfaction improvement, big data utilization, systematic management of workforce, and, planning and design quality. Conclusion: In the era of the Internet of everything, when complexity increases, this study presented a quality management direction suitable for new business methods challenging existing orders by drawing on quality management priorities.

A Study on Rational Alternative Comparison of Prior Review on Environmental Conditions for Basic Plan of Public Waters Reclamation (공유수면매립 기본계획 사전환경성검토의 합리적인 대안비교에 관한 연구)

  • Maeng, Jun-Ho;Cho, Kwang-Woo;Byon, Seong-Soo
    • Journal of Environmental Impact Assessment
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    • 제19권6호
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    • pp.563-571
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    • 2010
  • In carrying out the prior review on environmental conditions for basic plan of public waters reclamation, the important item is review on conditions of location on prearranged reclaimed land. In this study, environmental assessment which needs careful consideration in the first stage of selecting location is presented by analyzing environmental impact assessment on public waters reclamation projects for about 10 years. The assessment index for alternative comparison is divided into two parts according to importance level. What is most important in alternative comparison is the comparison on direct influence due to reclamation. In other words, it figures out damaged extent of natural shoreline as well as intertidal and infralittoral zones. Comparing influence extent due to reclamation through the 1st comparison on this is regarded as to be important. In case there is no significant difference by alternatives through the 1st assessment, the 2nd assessment should be carried out. In the 2nd assessment indexes are damaged quantity of benthic organism, change in seawater current, erosion, accumulation and exchangeable rate of seawater. The plan for selecting optimal location which minimizes environmental influence in establishing public waters reclamation plan is demonstrated through model cases. For this, 3 districts which have similar environment and scale are selected, and then comparison on location alternative is made through environmental assessment index. In addition, the comparison on 3 arrangement alternatives are conducted, targeting certain areas. It is thought that carrying out comparison review on respective areas in the same cities and counties, not merely comparing arrangement plan by selecting 1 targeting area in advance, is the most appropriate. Besides, selection of arrangement plan considering environment, which minimizes damage of natural shoreline and influence due to change of seawater current is required in alternative comparison on arrangement plan as well. In case of the prior review on environmental conditions though alternative comparison method presented in this study is carried out, it is safely said that the influence on ocean environment due to public waters reclamation can be minimized.

Effects of Emotional Dissonance and Job Burnout on the Psychological Health of the Nursery Teachers (어린이집 보육교사의 감정부조화, 직무소진이 정신건강에 미치는 영향)

  • Choi, Kwang Il;Lee, Won Jae
    • Journal of radiological science and technology
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    • 제39권4호
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    • pp.669-681
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    • 2016
  • This study collected data from 467 nursery teachers and it aimed to investigate the association between mental health and emotional dissonance and job burnout of the day care nursery teachers. Measurement tool was developed, most of the questions having 5-point scale. The data were analyzed structural equation model with the statistical package IBM SPSS 23 and AMOS 21 with 5% percent of significance level. Main results are as follows. First, it was found that emotional dissonance of nursery teachers working in day care centers showed significant effect on the mental health such factors as job-stress (relationships with children and parents and work overload). Second, emotional dissonance were found to have a significant effect on job burnout, too. Third, job burnout had a significant effect on the mental health, job stress and psychological wellbeing. Fourth, job burnout was found to mediate partially on mental health and emotional dissonance. These findings suggest the importance of mental health promotion programs for child care teachers working in the day care centers.

Characteristics of Peak External Pressure Acting on the Roof and Wall of the Low-Rise Buildings with Gable Roofs (박공지붕형 저층건축물의 지붕 및 벽면에 작용하는 피크외압의 분포 특성)

  • Jo, Won Geun;Won, Jong Ho;Ha, Young Cheol
    • Journal of Korean Society of Steel Construction
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    • 제21권3호
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    • pp.245-255
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    • 2009
  • The low-rise buildings with gable roofs are commonly used in a number of industries. In order to study the characteristics of peak external pressure coefficient on low-rise buildings with gable roofs, wind-tunnel test have been carried out. Wind-induced pressures were measured simultaneously at many points on wind-pressure models, typical of simple low-rise buildings with gable roofs, which have seven different roof slope with constant width(D), height(H), and length(D). The pressure measurements were made in one kind of turbulent boundary layer, which simulated the natural winds over typical suburban terrains at a geometric scale of 1/150. The results indicate that peak external pressure coefficient on the roof and wall edges were increased. The results compared with wind standard of KBC-2005 and standards of various nations. The comparative resultant, experimental result appeared very similar at AIJ-2004. But the results were somewhat larger then wind standard of KBC-2005.

Solution Methods for OD Trip Estimation in Stochastic Assignment (확률적 통행배정하에서 기종점 통행량추정 모형의 개발)

  • Im, Yong-Taek
    • Journal of Korean Society of Transportation
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    • 제24권4호
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    • pp.149-159
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    • 2006
  • Traditional trip tables are estimated through large-scale surveys such as household survey, roadside interviews, and license Plate matching. These methods are, however, expensive and time consuming. This paper presents two origin-destination (OD) trip matrix estimation methods from link traffic counts in stochastic assignment, which contains perceived errors of drivers for alternatives. The methods are formulated based on the relation between link flows and OD demands in logit formula. The first method can be expressed to minimize the difference between observed link flows and estimated flows, derived from traffic assignment and be solved by gradient method. The second method can be formulated based on dynamic process, which nay describe the daily movement patterns of drivers and be solved by a recursive equation. A numerical example is used for assessing the methods, and shows the performances and properties of the models.

Out-of-pocket Health Expenditures by Non-elderly and Elderly Persons in Korea (우리나라 성인과 노인의 개인부담 의료비용 지출의 관련요인)

  • Kim, Sung-Gyeong;Park, Woong-Sub;Chung, Woo-Jin;Yu, Seung-Hum
    • Journal of Preventive Medicine and Public Health
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    • 제38권4호
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    • pp.408-414
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    • 2005
  • Objectives : The purpose of this study was to determine the impact of the sociodemographic and health characteristics on the out-of-pocket health spending of the individuals aged 20 and older in Korea. Methods : We used the data from the 2001 National Public Health and Nutrition Survey. The final sample size was 26,154 persons. Multiple linear regression models were used according to the age groups, that is, one model was used for those people under the age of sixty-five and the other was used for those people aged sixty-five and older. In these analyses, the expenditures were transformed to a logarithmic scale to reduce the skewness of the results. Results : Out-of-pocket health expenditures for those people under the age of 65 averaged 14,800 won per month, whereas expenditures for those people aged 65 and older averaged 27,200 won per month. In the regression analysis, the insurance type, resident area, self-reported health status, acute or chronic condition and bed-disability days were the statistically significant determinants for both age groups. Gender and age were statistically significant determinants only for the non-elderly. Conclusions : The findings from this study show that the mean out-of-pocket health expenditures varied according to the age groups and also several diverse characteristics. Thus, policymakers should consider the out-of-pocket health expenditure differential between the elderly and non-elderly persons. Improvement of the insurance coverage for the economically vulnerable subgroups that were identified in this study should be carefully considered. In addition, it is necessary to assess the impact of out-of-pocket spending on the peoples' health care utilization.

Experimental Study on the Damping Estimation of the 5×5 Partial Fuel Assembly (5×5 부분핵연료 집합체의 감쇠추정을 위한 실험적 연구)

  • Lee, Kang-Hee;Yoon, Kyung-Ho;Song, Kee-Nam
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • 제16권2호
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    • pp.163-168
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    • 2006
  • The PWR Nuclear Fuel assembly consists of more than 250 fuel rods that are supported by leaf springs in the cells of more than 10 Spacer Grids (SG) along the rod length. Since it is not easy to conduct mechanical tests on a full-scale model basis, the small-scaled rod bundle $(5\times5)$ which is called partial fuel assembly is generally used for various performance tests during the development stage. As one of the small-scaled tests, a flow test should be carried out in order to verify the performance of the spacer grid to obtain the Flow-Induced Vibration (FIV) characteristics of the scaled fuel assembly over the specified flow range. A vibration test should be also performed to obtain the modal parameters of the assembly prior to the flow test. In this study, we want to develop the estimation procedure of the damping ratio for the scaled test assembly. For the damping factor of the partial fuel assembly and the grid cage at the first vibration mode, as one of the vibration tests, a so-called pluck testing has been performed in air as a preliminary test prior to in-flow damping measurement test. Logarithmic decrement method is used for calculation of the damping ratio. Estimated damping ratio of the partial fuel assembly is about $0.7\%$ with reasonable error of $2\%$ for the previous results. Nonlinear behavior of the partial fuel assembly might be stem mainly from the rod-grid support configuration.

Evaluation of Drilled Shaft's End Condition by Impact-Echo Method (충격반향기법에 의한 현장타설 말뚝기초의 선단 조건 평가)

  • Kim, Dong-Soo;Kim, Hyung-Woo
    • Journal of the Korean Society for Nondestructive Testing
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    • 제23권2호
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    • pp.89-97
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    • 2003
  • Experimental model studies were carried out to evaluate the end condition for drilled shafts by applying elastic impact on the top of the shaft, which is one of the various methods using stress waves. Typical impact responses corresponding to the various end conditions including free, fixed, rock-socketed, and soft-bottom with good and poor side contact conditions, were investigated. In order to simulate these renditions, mock-up shaft models made of cement mortar were used. Small-scale laboratory experiments were also performed, and field tests were carried out for the shafts that were socketed into weathered rock. It is found that the rock-socketed condition and depth of penetration into rock ran be identified from the reflection at the interface between the soil and rock in the waveform. The soft bottom rendition can be identified, only when the side contact between shaft and surrounding rock is poor, whereas it cannot be identified when the side contact is good because the waveform is similar to that of fixed end rendition.