• 제목/요약/키워드: sarcoma

검색결과 973건 처리시간 0.026초

생쥐에서 Sarcoma 180 및 Lewis Lung Carcinoma에 대한 Lactobacillus casei의 항암 효과 (Antitumor Activity of Lactobacillus casei against Sarcoma 180 and Lewis Lung Carcinoma in Mice)

  • 배형석;백영진;윤영호
    • 한국미생물·생명공학회지
    • /
    • 제21권3호
    • /
    • pp.247-255
    • /
    • 1993
  • Antitumor activity of Lactobacillus casei YIP 9018(LC9018) was studied in mice by using sarcoma 180(S-180) and Lewis lung carcinoma (3LL). Following the eatablishment of in vivo tumor models such as ascites form S-180, solid form S-180 and 3LL for estimating antitumor activity of Lactobacilli, optimal dose and injection route of heat-killed LC9018 for supperssion of local tumor were examined. Administration of 100ng/mouse of LC9018 significantly inhibited the growth of ascites form S-180, solid form S-180 and 3LL.

  • PDF

원발성 폐활막육종 -1례 보고- (Primary Pulmonary Synovial Sarcoma A Case Report)

  • 김맹호;김광택
    • Journal of Chest Surgery
    • /
    • 제30권12호
    • /
    • pp.1259-1261
    • /
    • 1997
  • 활막육종은 원시 간엽세포에서 원발한 악성연조직종양으로 주 호말부위는 슬관절, 족관절에 발생하는 것으로 되어 있으나, 폐에 원발한 활막육종은 거의 보고되지 않았다. 본원은 폐에 원발한 활막육종을 1례 경험하였기에 이에 보고하는 바이다.

  • PDF

Periarticular histiocytic sarcoma of a thoracic limb in a Rottweiler

  • Shin, Hyeok-Soo;Oh, Ye-In;Kang, Byung-Jae
    • 대한수의학회지
    • /
    • 제58권1호
    • /
    • pp.57-60
    • /
    • 2018
  • An 8-year-old, castrated, male Rottweiler was referred for evaluation of chronic right thoracic limb lameness and a progressively growing mass surrounding the right elbow joint. On admission, the dog's general health was good, without abnormalities detected on physical examination. The dog was diagnosed with periarticular histiocytic sarcoma. Although draining lymph nodes and lung metastases were suspected, palliative amputation was performed. Localized histiocytic sarcomas, with destructive lesions involving multiple bones of a joint and periarticular soft-tissue masses, are uncommon in dogs. This case report presents clinical findings, imaging characteristics, and histopathologic and immunohistochemical features of a periarticular joint histiocytic sarcoma.

Clear Cell Sarcoma of the Wrist: MRI Findings with Diffusion-Weighted Image and Histopathologic Correlation

  • Chung, Bo Yong;Lee, Seun Ah;Choi, Jung-Ah;Shim, Jung-Weon
    • Investigative Magnetic Resonance Imaging
    • /
    • 제20권2호
    • /
    • pp.136-139
    • /
    • 2016
  • Clear cell sarcoma is rare and difficult to diagnose. Herein, we present a case of clear cell sarcoma in the dorsum of the wrist with MRI findings, including diffusion-weighted imaging, and histopathologic correlation, which was initially diagnosed as giant cell tumor of tendon sheath.

Antineoplastic natural products and the analogues V - Antitumor Activity of Skullcapflavon II

  • Ryu, Sung-Ho;Ahn, Byung-Zun;Pack, Moo-Young
    • Archives of Pharmacal Research
    • /
    • 제8권4호
    • /
    • pp.253-256
    • /
    • 1985
  • The effect of skullcapflavon II, 5, 2'- dihydroxy-6, 7, 8, 6'-tetramethoxyflavone, on the growth of transplantable L 1210 and sarcoma 180 tumors in mice was studied. Intraperitional treatment of skullcapflavon II cased a significant (T/C = 166%) and a moderate (T/C = 122 %) prolongations of the life spans of ICR and $BDF_{1}$ mice respectively, which had been intraperitioneally inoculated with sarcoma 180 and L 1210 cells. Peritumoral injection of skullacapflavon II on the solid form of sarcoma 180 in mice inhibited the tumor growth strongly (Inhibition rate = 71%).

  • PDF

Undifferentiated Pleomorphic Sarcoma of the Descending Thoracic Aorta Mimicking Pseudoaneurysm with Periaortic Hematoma: a Case Report

  • Kim, Minsu;Bae, Young-A;Byeon, Sun-Ju;Choi, Jung-Ah
    • Investigative Magnetic Resonance Imaging
    • /
    • 제23권2호
    • /
    • pp.162-166
    • /
    • 2019
  • Undifferentiated pleomorphic sarcoma (UPS) arising from the descending thoracic aorta is a rare type of tumor. To our knowledge, only a few cases have been reported in the literature. We present computed tomography (CT) and magnetic resonance imaging findings of a 43-year-old male patient with undifferentiated pleomorphic sarcoma of the descending thoracic aorta, which showed enhancement on only magnetic resonance imaging (MRI). MRI with contrast enhancement may be useful in differentiating an aortic tumor from atherosclerotic disease.

후비강에서 발생한 저등급의 섬유점액성 육종: 증례 보고 및 문헌 고찰 (Low-Grade Fibromyxoid Sarcoma Arising in Posterior Nasal Cavity: Case Report and Review of the Literature)

  • 손정협;이기진;조경래
    • Korean Journal of Otorhinolaryngology-Head and Neck Surgery
    • /
    • 제61권11호
    • /
    • pp.624-629
    • /
    • 2018
  • Low-grade fibromyxoid sarcoma (LGFMS), a soft tissue tumor that has high recurrence and metastasizing potential, rarely occurs in the head and neck region. Therefore, the treatment for LGFMS in the facial area is challenging in terms of cosmetic and functional maintenance. The authors report a case of LGFMS in the posterior nasal cavity. It was completely removed in parallel with the nasal endoscopic and oral approach, but the lower margin was closed by preserving the soft palate. The patient is well without any recurrence or metastasis after 5 years of follow-up.

PET/CT로 혈전증과 감별된 원발성 폐동맥 육종 1례 (A Case of Primary Pulmonary Artery Sarcoma Mimicking Pulmonary Embolism: Role of PET/CT for Differential Diagnosis)

  • 임상수;홍구현;신재민;김윤섭;지영구;명나혜;박석건;박재석
    • Tuberculosis and Respiratory Diseases
    • /
    • 제62권3호
    • /
    • pp.232-236
    • /
    • 2007
  • 폐동맥 육종은 극히 드문 질환으로 폐동맥 혈전증과 혼동되는 경우가 많다. 육종에서는 FDG 섭취가 증가되므로 $^{18}F-FDG-PET$를 시행하면 FDG 섭취가 없는 색전증과 구별할 수 있지만 해상도가 떨어지는 단점이 있다. 그러므로 CT 영상을 접목한 PET/CT는 폐동맥 육종과 혈전증을 보다 선명하게 구별할 수 있다. 저자들은 혈전증과 감별이 어려운 폐동맥 병변에 대해 PET/CT로 폐동맥 육종의 진단에 도움을 받았던 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

폐 전이를 동반한 주폐동맥의 혈관 내막 육종 (Pulmonary Artery Intimal Sarcoma with Lung Metastasis)

  • 김인섭;정성철;김우식;배윤숙;신용철;정승혁;유환국;이정호;김병열
    • Journal of Chest Surgery
    • /
    • 제36권12호
    • /
    • pp.979-984
    • /
    • 2003
  • 원발성 폐동맥 육종은 매우 드문 질환이다. 임상증상과 방사선학적 소견이 폐동맥 색전증과 유사하기 때문에 진단 시 폐동맥 색전증으로 오진되는 예가 빈번하고, 본 질환의 빠른 진행속도로 인하여, 사망 후 부검을 통해 확인되는 예도 있다. 따라서 폐동맥 색전증으로 진단된 환자가 혈전의 원발병소가 불분명하면서 항응고제에 반응하지 않는다면, 원발성 폐동맥 육종을 의심해 보아야 한다. 폐동맥 색전증으로 진단받은 57세 남자 환자가 5개월간의 항응고제 치료 후에도 우측폐의 종괴모양 병변이 증가하고 주폐동맥 색전증의 크기가 증가되어 수술적인 치료과정에서 폐동맥 내막육종(Pulmonary artery intimal sarcoma)으로 확인되었다. 수술전 혈전으로 의심되었던 저음영의 종괴는 동결조직검사 상 폐동맥 육종으로 의심되었으며, 심낭에 침윤이 있었다. 그 병변과 독립적으로 우폐동맥과 폐실질에서도 혈관육종이 발견되었으며, 인공심폐기하에서 주폐동맥의 완전 절제술 시행 후 Gore-tex graft 치환술과 우측 전폐절제술을 시행하였다. 수술 후 2차례의 항암치료를 시행한 후에 퇴원하였다.

Survival of Patients with Ewing's Sarcoma in Yazd-Iran

  • Akhavan, Ali;Binesh, Fariba;Shamshiri, Hadi;Ghanadi, Fazllolah
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권12호
    • /
    • pp.4861-4864
    • /
    • 2014
  • Background: The Ewing's sarcoma family is a group of small round cell tumors which accounts for 10-15% of all primary bone neoplasms. The aim of this study was to evaluate the survival of Ewing's sarcoma patients in our province and to determine of influencing factors. Materials and Methods: All patients with documented Ewing's sarcoma/primitive neuroectodermal tumor(PNET) family pathology were enrolled in this study during a period of eight years. For all of them local and systemic therapy were carried out. Overall and event free survival and prognostic factors were evaluated. Results: Thirty two patients were enrolled in the study. The median age was 17.5 years. Twenty (65.2%) were male and 9 (28.1%) were aged 14 years or less. Mean disease free survival was 26.8 (95%CI; 13.8-39.9) months and five year disease free survival was 26%. Mean overall survival was 38.7 months (95%CI; 25.9-50.6) and median overall survival was 24 months. Five year overall survival was 25%. From the variables evaluated, only presence of metastatic disease at presentation (p value=0. 028) and complete response (p value =0. 006) had significant relations to overall survival. Conclusions: Survival of Ewing's sarcoma in our province is disappointing. It seems to be mostly due to less effective treatment. Administration of adequate chemotherapy dosage, resection of tumor with negative margins and precise assessment of irradiation volume may prove helpful.