Archives of Pharmacal Research
- Volume 8 Issue 4
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- Pages.253-256
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- 1985
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Antineoplastic natural products and the analogues V - Antitumor Activity of Skullcapflavon II
- Ryu, Sung-Ho (College of Pharmacy, Chungnam National University) ;
- Ahn, Byung-Zun (College of Pharmacy, Chungnam National University) ;
- Pack, Moo-Young (Department of Biological Science and Engineering, KAIST)
- Published : 1985.12.01
Abstract
The effect of skullcapflavon II, 5, 2'- dihydroxy-6, 7, 8, 6'-tetramethoxyflavone, on the growth of transplantable L 1210 and sarcoma 180 tumors in mice was studied. Intraperitional treatment of skullcapflavon II cased a significant (T/C = 166%) and a moderate (T/C = 122 %) prolongations of the life spans of ICR and