• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1273-1273
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• 2001

The efficiency of the luminal fermentation process influences overall efficiency of luminal production, animal health and reproduction. Ruminant production systems have a significant impact on the global environment, as well. Animal wastes contribute to pollution of the environment as ammonia volatilized to the air and nitrate leached to ground water. Microbial protein synthesis in the rumen satisfies a large proportion of the protein requirements of animals. Quantifying the microbial synthesis is possible by using markers for lumen bacteria and protozoa such as nucleic acids, purine bases, some specific amino acids, or by isotopic $^{15}N,^{32}P,\;and\;^{35}S$ labelled feeds. All those methods require cannulated animals, they are time-consuming and some methods are very expensive as well. Many attempts have been made to find an alternative method for indirect measurement of microbial synthesis in intact animals. The present investigations aimed to assess possibilities of NIRS for prediction of purine nitrogen excretion and ruminal microbial nitrogen synthesis by NIR spectra of urine. Urine samples were collected from 12 growing sheep,6 of them male, and 6- female. The sheep were included in feeding experiment. The ration consisted of sorghum silage and protein supplements -70:30 on dry matter basis. The protein supplements were chosen to differ in protein degradability. The urine samples were collected daily in a vessel containing $60m{\ell}$ 10% sulphuric acid to reduce pH below 3 and diluted with tap water to 4 liters. Samples were stored in plastic bottles and frozen at $-20^{\circ}C$ until chemical and NIRS analysis. The urine samples were analyzed for purine derivates - allantoin, uric acid, xantine and hypoxantine content. Microbial nitrogen synthesis in the lumen was calculated according to Chen and Gomes, 1995. Transmittance urine spectra with sample thickness 1mm were obtained by NIR System 6500 spectrophotometer in the spectral range 1100-2500nm. The calibration was performed using ISI software and PLS regression, respectively. The following statistical results of NIRS calibration for prediction of purine derivatives and microbial protein synthesis were obtained.(Table Omitted). The result of estimation of purine nitrogen excretion and microbial protein synthesis by NIR spectra of urine showed accuracy, adequate for rapid evaluation of microbial protein synthesis for a large number of animals and different diets. The results indicate that the advantages of the NIRS technology can be extended into animal physiological studies. The fast and low cost NIRS analyses could be used with no significant loss of accuracy when microbial protein synthesis in the lumen and the microbial protein flow in the duodenum are to be assessed by NIRS.

• 한국한의학연구원논문집
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• 제16권3호
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• pp.85-93
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• 2010

The aim of this review is to investigate clinical studies on oriental medicine treatment for obesity in Korean literature and to propose for the better method of clinical studies in order to seek more effective treatment. Electric searches were performed with NDSL, National assembly library, RISS4U, DBPIA, KISS, KMBASE, KoreaMed, Korean traditional knowledge portal and Oasis. Also, 21 major journals associated with oriental medicine in Korea were searched manually. Eighty three studies were included and analyzed in terms of study design, subjects, interventions, results and evaluation of safety. The numbers of controlled, non-controlled and case studies are respectively 26(31%), 43(52%) and 14(17%). Studies using sample size less than 30 accounts for 49% and studies using subjects diagnosed as obese or overweight by specific criteria were 35(42%). Studies which used more than 2 interventions or co-interventions were 76%. Clinical studies which used single herbal medicine were few and clinically studied single herbal medicine were limited to ephedra. More than half of 83 studies were studied for 8 weeks and less. 12% of 69 studies(except case studies) were not statistically analyzed and studies which evaluated safety of intervention were 22(27%) and reported adverse events were 9(11%). To improve the quality of clinical studies on oriental medicine treatment for obesity, studies need to use restricted number of interventions and subjects need to specifically diagnosed as overweight or obese. In addition, various kinds of single herbs need to be clinically studied based on experimental studies and herbalogy.

• Journal of Periodontal and Implant Science
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• 제41권1호
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• pp.17-22
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• 2011

Purpose: Nitric oxide (NO) has been known as an important regulator of osteoblasts and periodontal ligament cell activity. This study was performed to investigate the relationship between NO-mediated cell death of human periodontal ligament fibroblasts (PDLFs) and N-methyl-D-aspartic acid (NMDA) receptor antagonist (+)-5-methyl-10, 11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine hydrogen maleate (MK801). Methods: Human PDLFs were treated with various concentrations (0 to 4 mM) of sodium nitroprusside (SNP) with or without $200\;{\mu}M$ MK801 in culture media for 16 hours and the cell medium was then removed and replaced by fresh medium containing MTS reagent for cell proliferation assay. Western blot analysis was performed to investigate the effects of SNP on the expression of Bax, cytochrome c, and caspase-3 proteins. The differences for each value among the sample groups were compared using analysis of variance with 95% confidence intervals. Results: In the case of SNP treatment, as a NO donor, cell viability was significantly decreased in a concentration-dependent manner. In addition, a synergistic effect was shown when both SNP and NMDA receptor antagonist was added to the medium. SNP treated PDLFs exhibited a round shape in culture conditions and were dramatically reduced in cell number. SNP treatment also increased levels of apoptotic marker protein, such as Bax and cytochrome c, and reduced caspase-3 in PDLFs. Mitogen-activated protein kinase signaling was activated by treatment of SNP and NMDA receptor antagonist. Conclusions: These results suggest that excessive production of NO may induce apoptosis and that NMDA receptor may modulate NO-induced apoptosis in PDLFs.

• 한국보건간호학회지
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• 제7권1호
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• pp.49-65
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• 1993

This study had conducted to push our society for getting some proper measures of the anti-drug abuse and adopting this study as a fundamental data for the school health education. Sample subjects were the 3rd grade of high school in Chungnam Province and the number were 1,014. The data had been collected on Dec. 3th-8th, 1990 according to the tool of Institute on Drug Abuse of Korea. And then Frequency and $x^2-test$ were need to analyse of data by SPSS-X program. The results of this study could be summarized as follows. 1. They had used 14 kinds of drugs: $70.1\%$ of the subjects students used alcohol, $69.2\%$ analgesics, $38.6\%$ cigarette, $15.0\%$ stimulants, $14.7\%$ antitussives, $11.2\%$ antithistamines, $8.9\%$ hypnotics, $7.1\%$tranquilizers, $4.2\%$ inhalants, $2.3\%$ marijuana, $1.4\%$ hallucinogens, $0.9\%$ cocaine, $0.6\%$ amphetamines, and $0.6\%$narcotics. The boys' drug using rate is higher than girls' except in analgesics and stimulants. 2. With respect to misbehaving, $43.0\%$ of the students said they had pop houses, $42.4\%$ adult video, $17.4\%$ unexcused absence from school, $11.0\%$ dangerous weapon, $9.1\%$ sexual intercourse, $70.1\%$ disappearance from home, 8.0% blackmail, and $6.0\%$ assault. In every kinds of misbehaving, the boys' misbehaving rate is higher than the girls'. 3. Almost every kinds of drugs have the students first used at the age of 15 through. 18. And $13.8\%$ of the students smoked every da·y and $1.7\%$ drank every day. 4. The frequency of the drug using such as cigarette (p<.01), marijuana (p<.05), cocaine (p<.05) and narcotics (p<.05) showed the stastically significant differences according to the religions of the subjects 5. The subjects who has complaints about someone use more drugs than the ones who doesn't, and who doesn't have any complaints about five elements have never used drugs such as marijuana, cocaine, amphetamines, narcotics, hallucinogens, and inhalants. 6. The drug using subjects have the more experiences of adult video, pop houses, and unexcused absent from school than the non-drug using ones. It means that the subjects who use drug were apt to do misbehaving more often than the ones who have never used them, and delinquent boys and girls use more drugs.

• 한국지구과학회지
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• 제24권6호
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• pp.524-532
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• 2003

이 연구의 목적은 진자 과제에서 학생들의 가설 생성에 있어서 귀추적 추론 능력이 중요한 역할을 한다는 가설을 검증하고자 하는 것이다. 가설을 검증하기 위하여 5학년 학생들을 대상으로 하여 진자 운동에 대한 가설 생성 검사와 진자의 길이에 대한 선지식 검사를 실시하였다. 진자의 길이에 대해 선지식을 가지고 있는 많은 학생들이 그네 과제에 대한 가설 생성에 선지식을 적용하지 못하였다. 이러한 결과는 학생들이 가설 생성에 실패한 이유가 단지 선지식이 없어서가 아니라 오히려 귀추적 추론 능력이 부족한 것과 관련된다. 학생들이 성공적으로 가설 생성을 하기 위해서는 선지식 뿐만 아니라 귀추적 추론능력도 요구된다. 그러므로 이 연구는 가설 생성 과정에 있어서 선지식 이외에도 귀추적 추론 능력이 중요한 역할을 한다는 주장을 지지한다. 이 연구는 학생들의 가설 생성 능력을 계발하기 위해서는 과학 교육에서 과학적 선언적 지식 뿐만 아니라 귀추적 추론 능력에 대한 교육도 함께 제공되어야 함을 시사한다.

• 한국콘텐츠학회논문지
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• 제14권1호
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• pp.209-222
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• 2014

본 연구는 국내에서 발표된 사회복지분야의 메타분석 논문을 미국 심리학회에서 제시한 메타분석 보고기준에 따라 연구방법론 측면에서 고찰하고자 하였다. 이를 위해 사회복지분야의 메타분석 논문 26편을 대상으로 5가지 준거별로(제목 및 초록, 서론, 방법, 결과, 논의) 분석하였다. 분석결과는 첫째, 제목 및 초록 준거에서는 메타분석 방법에 대한 제시항목을 제외하고 양호한 것으로 나타났다. 둘째, 서론 준거에서는 상당수의 항목에서 기술이 양호한 것으로 나타났다. 셋째, 방법 준거에서는 전반적인 보고기준이 미흡한 것으로 나타났는데 특히 코딩절차에 대한 보고기준이 상당히 미흡한 것으로 나타났다. 넷째, 결과 준거에서는 대체로 양호했지만 표와 그래프 제공이 잘 보고되지 않는 것으로 나타났다. 다섯째, 논의 준거에서는 대체로 양호한 것으로 나타났다. 이러한 결과를 바탕으로 메타분석 연구물을 평가할 수 있는 타당성 확보에 필요한 보고기준과 시각을 제공하여 메타분석을 통한 사회복지학의 학문적 발전을 위한 시사점을 제시하고자 하였다.

• 한국가금학회지
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• 제22권3호
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• pp.167-178
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• 1995

The purpose of this research was to get basic information for the development of Korean native chicken industry by reviewing the current native chicken farm management and marketing situation of native chicken products(meat and eggs). The research was carried on the basis of the farm field survey covering 210 native chicken feeders out of 9 different local areas, and the results were as follows ; 1. Average raising size of native chicken flocks of sample farms was 1,787 heads and about 50% of those farms raised less than 500 heads chickens for self-sufficiency or on the side. 2. Most farmers made the decision to start on feeding native chickens in small scale with small amount of capital without sound feeding program, and their decision was mainly influenced by recommendation of mass-media( 19.5%) and neighbors (17.2%). 3. The average income per farm earned by raising the native chickens was 13,719 Won, and income per head of chicken was 8,800 Won. 4. About 40% of feeders expressed that the poor marketing management and lack of capital were the bottleneck to native chicken farm management. 5. About 70% of feeders evaluated the prospect of native chicken industry positively and so, about 60% of feeders hoped to expand the raising size in the future. 6. Most farmers directry made a bargain with marketer including middleman and enduser in selling the chicken products because there was not established special marketing system for native chicken products. 7. The sales age of native broiler was about 16~20 weeks and average body weight of broiler was 1.5~2.0 kg. And farm recieved price was not decided on the basis of each body weight or meat quality but only number of heads. 8. The average first egg-laying age of chickens was about 165 days and average annual laying rate was only about 56%. 9. In order to develop the successful Korean native chicken industry, followings are recommended ; 1) Reducing the production costs and increasing the productivity of native chickens should be carried out through technological research and development for sound feeding program of native chickens and sufficient fund supply. 2) Orderly native chicken marketing and pricing system should be established to give good vision about native chickens to farmers and to delight the consumers. 3) The measures for product differentiation including meat quality and nutritional value of native chicken products against other improved chickens should be actively taken by feeders and government.

• Journal of Preventive Medicine and Public Health
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• 제36권1호
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• pp.11-23
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• 2003

Objectives : The 1990s has seen advances in the conceptualization of self-perceived health status which has important roles for individual health and the quality of life. Many types of standardized questionnaires have been developed with the current wide use of SF-36, NHP, andEuroQol. However, the outcomes of these tools may be different with regard to regional, cultural and emotional backgrounds. The purpose of this study was to trial the development of a Korean Health Profile (KHP 1.0) to measure the self-perceived health stati of Koreans. Methods : The KHP 1.0 was designed on the basis of the Medical Outcome Study Form 36 (SF-36), the Nottingham Health Profile (NHP), and the EuroQOL. It was composed of 9 scales; physical functioning, role limitation-physical, pain, general health, energy, social isolation, sleep, role limitation-emotional, and e-motional health. Self-reported chronic disease conditions, and the Zung's Self-Rating Depression Scale (SDS), were also checked for the evaluation of clinical validity. This study was conducted, from December 2000 to January 2001, on 800 middle-aged parents, with four high school students, with 100 retest sets being conducted two weeks later. From the 800 subjects there were 588 complete responses (effective response 73.5%). The reliability of the test-retest results, and the factor analysis on the validity of the KHP 1.0 components, were evaluated using the SPSS (ver 10.0) software. Results : The reliability of the KHP 1.0 was good with Cronbach's alpha (>0.6), test-retest correlation coefficients (>0.5), but with no significant differences from the paired t-test. From the psychometric validity tests, the 9 scales of the KHP 1.0 were divided into two components; physical and mental, and trimmed to the established model with 55% of the total variance, with the exception of role limitation-emotional. The clinical validity on the basis of the comparison for the four characteristic groups; healthy, physical conditions only, mental conditions only, and physical and mental conditions were also good. Conclusions : The KHP 1.0 appears to be a valid measurement tool of self-perceived health stati of Koreans, although there are limitations, i.e. sample size was too small, a limited number of middle-aged subjects, and it was based on unconfirmed diagnoses, etc. Therefore, further study is required to standardize the assessment.

• 한국학교보건학회지
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• 제1권2호
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• pp.34-49
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• 1988

The purpose of this study is to identify the status of school health and analyze affecting factors of school nurses' self confidence and nursing activities of the secondary school in Seoul. The data was collected from 13th of August to 30th of October. The self reported questionairs were distributed during one of the school nurses seminars held in Seoul and 93 secondary school nurses answered. Analysis of the data was done utilizing SPSS for percentage, mean, T-test ANOVA and Pearson Correlation Coefficients. The results of study are summerized as follows; 1. General Characteristics The mean age of the subjects was 33.4 and mean length of experience as a school nurse was 7.3 years. 79.5 percent of them had clinical experiences and the mean clinic experience was 2.1 years. The majority of them were graduate of the baccalaureate nursing programs and 82.8 percent of them were married. 72.0 percent of the sample had religion, and 60.2 percent of them were in the national or public schools. 90.3 percent of them had independent duty. 2. The status of school health resources In average, there were 2,445 students, 37 classes and 63 teachers per school nurse. 48.4 percent of them were aware of the school budget. The budget for school health was 585,000 won per school in average. 30.0 percent of the schools had school health organization. The schools whose health clinics were on the first floor consisted of 79.3 percent, among them 42.9 percent were on the center of the building office. 3. Activities of school health nursing The average number of students using health clinic were 430 per month. The majority of the problem was digestive problem. There were 7.5 times of mean correspondences with parents per year. The activities of the school nurses were clinic management (29.0%), health care services (23.5%) and health education (14.1%). 4. The degrees of self confidence of the school nurse and nursing activities Self confidence measured by 6 items of self-reported questionaires scored by 4 point Likert Scale revealed. The nurses' self-confidence was 2.922 in clinic management, 2.909 in health education, 2.759 in program planning and evaluation, 2.757 in health care services, 2.692 in management of school environment, and 2.250 in operation of school health organization. The nursing activities scored by 2 point. The nursing activities was 1,870 in program planning and evaluation, 1.853 in health education, 1.843 in clinic management, 1.739 in health care services, 1.696 in management of school environment and 1.265 in operating of school health organization. 5. Factors affecting self confidence and nursing activities of school nurses The general characteristics of the school nurses and the school health resources were related to self confidence and nursing activities. The most significant variable to nurses' self confidence was type of the school ownership and the presence of school health organization was the most significant factor to nursing activities.

• 자원ㆍ환경경제연구
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• 제22권2호
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• pp.215-250
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• 2013

"자원의 저주"란 천연자원이 풍부한 국가들이 오히려 경제적으로 낙후되어 있다는 학설이다. 본 논문에서는 기존 연구들과 달리 천연자원 보유 및 생산량이 경제수준과 강한 양(+)의 회귀계수를 보이는 것으로 분석하고 있다. 이러한 결과는 1인당 자본스톡 등 경제성장과 연관된 다양한 설명변수들을 포함시켰을 때에도 유지되고 있다. 이러한 점에서 자원의 저주가 실제로 존재하는 지는 의문이다. 다음으로 천연자원이 경제에 미치는 긍정적인 영향을 통제하고 나서 천연자원 보유 및 생산량에 따른 한 나라의 제도발전 정도를 회귀분석한 결과, 구소련지역 국가들을 포함시키게 되면 선행연구인 Alexeev and Conrad(2009)와는 달리 천연자원 보유량이 제도발전 정도와 음(-)의 회귀계수를 가질 수도 있는 것으로 나타났다. 그러나 이러한 음(-)의 회귀계수는 구소련지역 국가들을 분석대상에서 제외하면 모두 통계적 유의성을 상실하였으며, 통계적으로 유의하지는 않지만 상당수 분석결과에서는 양(+)의 회귀계수도 도출되었다. 즉, 음의 회귀계수는 구소련지역 국가들에 의해 도출된 것이라고 할 수 있다. 이러한 결과는 구소련 지역 국가들의 체제이행기 서방자본의 유입으로 인한 천연자원 보유 및 생산량의 급증과 체제변환에 따른 정치경제적 불안정이 동시에 발생한 때문이며, 일시적이고 다분히 우연에 의한 결과로 추정된다. 따라서 천연자원 보유량이 제도 발전 정도에 부정적인 영향을 미친다는 주장도 그 근거가 다소 희박하다고 하겠다.