• 제목/요약/키워드: safety inventory

검색결과 298건 처리시간 0.023초

정상인에서 스트레스와 불안에 대한 돌외추출물의 효과와 안전성에 관한 무작위 배정 이중 맹검 임상시험 (Randomized, Double-Blind Study of Efficacy and Safety of Gynostemma pentaphyllum Ethanol Extract in a Normal Population)

  • 정성해;이명구;박미숙;김재문
    • 한국임상약학회지
    • /
    • 제21권2호
    • /
    • pp.131-137
    • /
    • 2011
  • The purpose of this study was to evaluate the clinical efficacy of a standardized special ethanol extract from Gynostemma pentaphyllum as a management for anxiety and stress of normal population. This is a two-arm, parallelgroup, randomized, double blind clinical trial comparing Gynostemma pentaphyllum extract 200 mg bid (GP-EX, n=48) or placebo bid (n=54). The main outcome measures were the decrease in anxiety sensitivity index (ASI), the State version (S-STAI) of the Stait-Trait Anxiety Inventory (STAI) and the Trait version (T-STAT) of the STAI from baseline over a 6 weeks treatment period. In more anxious group (S-STAI50 or ASI19), the anxiety in group with GP-EX was decreased significantly than one in normal population with placebo [S-STAI50: T-STAI = from $57.7{\pm}6.5$ ($mean{\pm}S.D.$) to $46.8{\pm}11.2$ in normal population with GP-EX, p=0.002 vs. from $54.1{\pm}9.9$ to $49.0{\pm}9.6$ in normal population with placebo, p>0.05; ASI19: T-STAI = from $47.2{\pm}12.0$ to $42.4{\pm}11.1$ in normal population with GP-EX, p=0.022 vs. from $48.7{\pm}11.5$ to $46.0{\pm}10.4$ in normal population with placebo, p>0.05]. The most frequently reported adverse reactions considered possibly related to treatment were mild gastrointestinal events. GP-EX is more effective than placebo and is well tolerated as a therapy for anxiety and stress of normal population.

A Review of IOSS Design Standardization Technology for Aluminum Alloy Handrail of Offshore Platform

  • Kim, Yeon-Ho;Park, Joo-Shin;Shin, Hyun-Chang;Kim, Sung-Jun;Park, Dae-Kyeom;Ha, Yeon-Chul;Seo, Jung-Kwan
    • 한국해양공학회지
    • /
    • 제34권3호
    • /
    • pp.208-216
    • /
    • 2020
  • The Integrated Offshore Standard Specification (IOSS) involves Korean shipyards, classification societies, research institutes, the Korean industrial society, engineering companies, and oil companies with the objective of reducing costs and risks without compromising safety in international offshore engineering procurement construction (EPC) projects using new standardized bulk components and qualification procedures. The activities of the IOSS include the analysis of the existing rules and regulations to achieve the best standardization, which is reflected in the best practices, and minimize the variables in regulations and rules. In addition, a standard inventory of shapes and dimensions, referred to as specifications, is proposed in the IOSS. In this paper, the aluminum tertiary standardization part (IOSS S102-1/2 S104: Specification for Structural Tertiary Design) is presented with the details of the procedures, background reviews, and cost-benefit analyses of the design and verification methods for standard designs in the IOSS standardization items. Based on the cost-benefit analysis, the application of standardized aluminum tertiary items to offshore projects has significant advantages in terms of maintenance and repair compared to the carbon steel tertiary items utilized in current industrial practices.

프로필렌 회수공정에서 화재 및 폭발 사고의 피해영향 해석 (Consequence Analysis for Fire and Explosion Accidents in Propylene Recovery Process)

  • 한성환;이헌창;박교식;김태옥
    • 한국가스학회지
    • /
    • 제18권1호
    • /
    • pp.52-60
    • /
    • 2014
  • 본 연구에서는 석유화학공정에서 잠재위험요소를 확인하고, 사고 결과분석을 통해 안전대책 수립 등의 위험관리 방안을 제시하고자 하였다. 이를 위해 프로필렌 회수공정(PRP)에서 현실적인 상황을 고려한 누출 시나리오를 선정하고, PHAST RISK(ver. 6.7) 프로그램을 사용하여 화재 및 폭발 사고의 피해범위를 산출하고, 피해영향을 해석하였다. 그 결과, 6개의 PRP 공정지역 중에서 디프로파나이저 지역, 디에타나이저 지역 및 히트펌프 지역에서는 화재 및 폭발 사고의 피해범위가 매우 크게 나타났다. 따라서 제트화재가 발생하는 공정지역에서는 200 m의 반경 내에서 사람이 상주할 수 있는 건물을 설치하지 않는 것이 바람직하고, 재고량과 압력이 큰 공정지역에서는 사고위험을 사전에 예방해야 하고, 사고 발생 시에는 신속한 대처방안 수립이 요구되었다.

일부 산업장 근로자들의 직무스트레스 분석 (Occupational Stress of Workers in the Manufacturing Industry)

  • 김순례;이정희
    • 한국직업건강간호학회지
    • /
    • 제9권2호
    • /
    • pp.110-120
    • /
    • 2000
  • The purpose of this study was to examine which factors affected the job stress of workers in the manufacturing industry. The subjects were 128 workers in automobile component manufacturing companies located in Kyonggi-do province. Data were collected through self-reporting technique for 8 days, October 24-31, 2000. The instrument to test the work related truss was NIOSH's Work-related Stress Inventory revised by Korea Occupational Safety and Health Association(KOSHA) in 1999. The collected data were analysed with SAS. and frequency, percentage, mean value, standard deviation, t-test, ANOVA. Scheffe's post hoc test and Pearson's Correlation Coefficients. The major findings were as follows: 1. Mean job stress score for the job-related stress was $2.6{\pm}0.5$ on the basis of 5.0 points. Job stress was significantly different according to gender. The stress by role conflict showed higher score than the stress by role ambiguity. 2. Discretionary power(freedom to determine) of workers was scored $2.6{\pm}0.7$ on the basis of 5.0 points. And it was significantly different according to gender, duration of work and shift experience. 3. The work environment scored $2.2{\pm}0.3$ on the basis of 3.0 points and significant difference according to gender, age, marital status, type of employment, type of service, and shift work. 4. Role ambiguity showed significant negatively correlate with job control(r=-.32, P=.000) and decision making(r=-.31, P=.000). And decision making showed positively correlated with job control(r=.62, P=.000), and role conflict(r=.26, P=.003).

  • PDF

핵변환 잔류 고준위 방사성 폐기물 처분 성능 평가 (Safety Assessment on Disposal of HLW from P&T Cycle)

  • 이연명;황용수;강철형
    • 터널과지하공간
    • /
    • 제11권2호
    • /
    • pp.132-145
    • /
    • 2001
  • 핵변환 후 영구 처분될 가압경수로 및 중수로용 사용후 핵연료에 대한 인간 생태계에 대한 영향을, 직접 처분하는 경우와 비교해 보았다. 심지층 처분된 용기에 저장된 사용후 핵연료로부터 유출된 방사성 핵종들이 공학적 방벽을거쳐 결정질 기반암 내 균열대를 통해 지하수의 흐름을 따라 이동하면서, 다양한 지질 및 암종을 거쳐 생태 환경으로 도달한다는 핵종 유출 시나리오 중 가장 보수적인 시나리오인 우물 시나리오에 대한 위해도를 평가하여 상대인 환경친화성을 정량적으로 제시하였다. 현재 국내에 가속기와 미임계형 원자로를 함께 사용하는 핵변환 시스템과 임계형 원자로와 같은 핵변환시스템이 개념적인 수준에서 개발되고 있어, 이 연구를 통해 향후 핵변환시스템 연구에서 요구되는 항목들도 기술적 개선, 경제성 제고, 환경 친화성, 그리고 수용성 측면에서 제시해 보았다.

  • PDF

어머니의 신생아에 대한 지각사정에 관한 연구 (A Study on Assessment of Mothers Perception of a Newborn Baby)

  • 이자형
    • 대한간호학회지
    • /
    • 제16권3호
    • /
    • pp.67-77
    • /
    • 1986
  • The research was carried out in order to assess, at an early stage, the potential barrier in mother-child relationship in the childs' development by using the screening tool. Consequently, after modifying the Neonatal Perception Inventory developed by Broussard and testing its reliability. It has been applied to 152 mothers at the hospital of three universities in Seoul from August 1 to September 30, 1986. The data was analyzed by S.P.S.S. pro-gram and the results were as follows: 1) Mothers perceived the newborn as an individual, and evaluated their baby higher than other babies. 2) Mothers indicated difficulties in their role performance in the fellowing order-bathing, safety, detecting pain or suffering, and feeding. 3) Mothers' perception of a newborn was positive for 75% of the mothers. 4) The factor analysis of the modified tool using principal components analysis and Varimax rotation resulted in the two factors: Factor 1, Baby as an individual: Factor Ⅱ, Performances are required to meet the new-born's needs. 5) The difference in mothers' individual characteristics such as the number of childbirth, the desire to get pregnant or not, the type of deli-very, and the sex of the newborn did not influence on a mothers' perception of her newborn. As seen above, most of the mothers perceived their newborns as able individuals and expressed difficulties involved in taking care of the newborn. Also most of the mothers perceived their babies positively. My point here is, we ought to observe those mothers who perceive their babies negatively, and then compare them with those mothers who perceive their babies extremely positive or extremely negative. In the future, for more comprehensive assessment tool for maternal perception of the newborn, a repetitive verification and modification of this tool is demanded. At the same time, father's perception of the newborn should be included.

  • PDF

자음강화탕 투여 후 상열감의 호전을 보인 타목시펜 복용 중인 유방암 환자 1례 (Case Study of a Breast Cancer Patient Accompanying with Hot Flush by Tamoxifen Whose Condition Was Improved by Jayeumganghwa-tang)

  • 정홍매;이연월;유화승;조종관
    • 대한한방내과학회지
    • /
    • 제31권2호
    • /
    • pp.395-400
    • /
    • 2010
  • Objective : To observe the effectiveness of Jayeumganghwa-tang on hot flush of a breast cancer patient who takes tamoxifen. Methods : For six weeks a dosage witch contained 13.92g of Jayeumganghwa-tang was administered 3 times (30 mins after meal) per day, for improvement of hot flush. No other therapies like hormone therapy or substituted therapy were done. Results : As a result of 6 weeks of Jayeumganghwa-tang therapy, the patient who suffered hot flush on taking tamoxifen showed improvement on several indices, including frequency, intensity and point of hot flush, Beck Depression Inventory-K (BDI-K) which shows uneasiness and sadness, and also Functional Assessment Cancer Therapy - Breast (FACT-B) which is an index of life quality of breast cancer patients. But no changes on female hormones like follicle-stimulating hormone (FSH) or luteinizing hormone (LH) were observed. Conclusion : This case demonstrates 6 weeks of Jayeumganghwa-tang taking had no effect on female hormones but can reduce the hot flush by tamoxifen. This shows minimum evidence of safety and efficacy of Jayeumganghwa-tang on hot flush of breast cancer patient. However this is a single case study so further case-series research should be compiled.

토립자 유실을 고려한 로지스틱 회귀분석 및 GIS 기반 도시 지반함몰 취약성 평가 (Logistic Regression and GIS based Urban Ground Sink Susceptibility Assessment Considering Soil Particle Loss)

  • 서장원;류동우;염병우
    • 터널과지하공간
    • /
    • 제30권2호
    • /
    • pp.149-163
    • /
    • 2020
  • 본 연구에서는 지리정보시스템 환경에서 지하매설물 정보를 이용하여 토립자 유실을 고려한 도시 지반 함몰 취약성을 평가하였다. 지하 환경에서 물의 흐름이나 지하수위 변화에 의한 토립자 유실은 지하공동의 발생과 확장을 유도하고, 이는 지반함몰 발생에 직접적인 원인이 된다. 토립자 유실은 지하 환경에 따라 그 정도가 달라질 수 있기 때문에 본 연구에서는 지하매설물 2종(상수도 관망, 하수관로)과 지하철 선로 권역별로 지반함몰에 영향을 주는 인자를 각각 4개씩 선정하였다. 로지스틱 회귀분석 기법을 이용하여 지하매설물 및 지하철 선로 권역 별로 지반함몰 이력과 영향인자 간의 상관성을 분석하고 회귀식을 도출하였으며, 이를 토대로 3개의 지반함몰 취약성 지도를 작성하였다. 본 연구 결과는 도시 지반함몰 위험 예·경보 시스템 구축을 위한 지반함몰 고위험지역 및 지반 안전 상시 모니터링 지역 선정 근거에 대한 기초 자료를 제공할 수 있을 것으로 기대한다.

환경적으로 건전한 선박 재활용에 관한 국제 동향 (International Trend in Environmentally Sound Management of Ships Recycling)

  • 윤종휘;국승기;임재동
    • 해양환경안전학회:학술대회논문집
    • /
    • 해양환경안전학회 2008년도 춘계학술발표회
    • /
    • pp.11-17
    • /
    • 2008
  • 우리나라는 국적외항상선의 수가 2006년 1월 기준으로 546척, 13,716,733 G/T에 이르는 세계 제 8위의 해운강국이다. 선박은 건조시로부터 25년에서 30년 정도 운항하면 그 수명을 다해 다른 용도로 변경되어야한다. 수명이 다 된 노후 선박의 처리방법으로 재활용이 가장 나은 방범으로 대두되고 있으나 여러 가지 환경적 규제와 노동 규제에 의해 현재 선진국에서는 거의 이루어지지가 않고 비교적 법규제가 느슨한 개발도상국으로 옮겨지고 있으나 국제적으로는 선박도 하나의 폐기물로 보고 국가간 이동을 금지하는 추세이다. 본 연구에서는 선박해체산업현장의 열악한 작업환경과 환경피해의 심각성 해결을 위한 국제적인 동향을 알아보고자 하였나. IMO, UNEP, ILO 에서는 선박의 해체 작업에 참여하는 작업자들의 건강과 안전을 보호 하고 환경오염을 방지하기 위하여 선박내의 유해물질을 목록화하여 유해물질을 관리하도록 하는 방안을 마련하고 있으며, 선박의 재활용과 관련한 바젤협약, IMO Guideline, ILO Guideline, IMO Convention Draft를 통해 세계적인 추세를 알아보았다.

  • PDF

복합재해 영향을 고려한 산불 후 산사태 잠재적 피해 위험도 분석 (Analysis of the potential landslide hazard after wildfire considering compound disaster effect)

  • 이종욱;이동근;송영일
    • 한국환경복원기술학회지
    • /
    • 제22권1호
    • /
    • pp.33-45
    • /
    • 2019
  • Compound disaster is the type that increases the impact affected by two or more hazard events, and attention to compound disaster and multi-hazards risk is growing due to potential damages which are difficult to predict. The objective of this study is to analyze the possible impacts of post-fire landslide scenario quantitatively by using TRIGRS (Transient Rainfall Infiltration and Grid-Based Regional Slope-Stability Analysis), a physics-based landslide model. In the case of wildfire, soil organic material and density are altered, and saturated hydraulic conductivity decrease because of soil exposed to high temperature. We have included the change of soil saturated hydraulic conductivity into the TRIGRS model through literature review. For a case study, we selected the area of $8km^2$ in Pyeongchang County. The landslide modeling process was calibrated before simulate the post-wildfire impact based on landslide inventory data to reduce uncertainty. As a result, the mean of the total factor of safety values in the case of landslide was 2.641 when rainfall duration is 1 hour with rainfall intensity of 100mm per day, while the mean value for the case of post-wildfire landslide was lower to 2.579, showing potential landslide occurrence areas appear more quickly in the compound disaster scenario. This study can be used to prevent potential losses caused by the compound disaster such as post-wildfire debris flow or landslides.