• Journal of The Korean Association For Science Education
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• v.30 no.2
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• pp.181-191
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• 2010

In this study, we have come to classify experiment illustrations inserted in chemistry I textbook according to types (photographs and pictures) and roles (instruments, reagents, process and results). Also, in the case of person in illustrations not following the safety rules or mishandling instruments in the experimental process, we have come to define it as an 'error'. The problem is that, students tend to accept these errors unquestioningly and as a result, during the experiments, safety concerns can arise. Besides, the mishandling of instruments can lead to the wrong result of experiments. These errors are thought to be caused in the process of making illustrations. Therefore, to minimize errors in the illustrations for the experiments, experts specializing in illustrations should participate in the actual experimental illustrations process.

• Journal of the Society of Disaster Information
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• v.15 no.1
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• pp.12-19
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• 2019

Purpose: The purpose of the study is to reduce the fire of the same type by analyzing the form which is mainly generated based on the result of the fire investigation through the experiment to reproduce, since the candle fire is repeated every year with the same type. Methods: For the analysis of candle flame, 4 kinds of methods such as acrylic recharge test, FOMEX acrylic recharge test, general combustible recharge test, and natural fire extinguishing test of candle were conducted. Results: It was confirmed that continuous burning is difficult to be achieved without contact of combustible materials around. Conclusion: In order to prevent a candle fire, it is important to check the safety of the surrounding area. It is also considered to introduce safety regulations such as finishing with a fireproof material such as a silver foil at the terminal end.

• Korean Journal of Veterinary Service
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• v.46 no.3
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• pp.193-202
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• 2023

Porcine epidemic diarrhea is an infectious intestinal disease caused by the porcine epidemic diarrhea virus (PEDV). Especially, when suckling piglets are infected, the mortality rate is close to 100%. PEDV is classified into G1 and G2 types based on genetic differences. The G2 type PEDV outbreak in the United States in 2013 was highly pathogenic and contagious, and it has spread worldwide and caused continuous economic losses. Most commercial vaccines used are G1 type vaccines, and existing vaccines do not fully protect piglets due to genetic differences. In this study, we evaluated the safety of the newly developed G2 type attenuated HSGP vaccine strain by inoculating it into piglets and testing whether the vaccine virus spreads to the non-vaccinated, negative pigs and whether the vaccine reverts to its virulence during serial passage experiments. Each experiment lasted for 7 days for each passage, and fecal viral titers, clinical symptoms, and weight gain were measured daily. After the experiment, necropsy was performed to measure intestinal virus titer and pathological evaluation. As a result of the first passage, no transmission of the vaccine virus to negative pigs co-housed with vaccinated pigs was observed. In addition, after four consecutive passage experiments, the clinical symptoms and small intestine lesions were gradually alleviated, and no virus was detected in the feces in the fourth passage experiment. Therefore, it was concluded that the vaccine was safe without virulence reversion in accordance with the guidelines of the current licensing authority. However, further studies are needed on the genetic changes and biological characteristics of the mutant virus that occur during successive passages of the attenuated vaccine since the replication and clinical symptoms of the virus increased until the third passage during successive passages of the vaccine virus. Based on this study, it was concluded that virulence reversion and safety evaluation of attenuated vaccines through serial passage in target animals can be useful to evaluate the safety of attenuated viruses.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.270-272
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• 2022

Safety is one of the factors that prevent clinical drugs from being distributed on the market. In the case of neurotoxicity, which is the main cause of safety problems caused by drug side effects, risk assessment of drugs and compounds is required in advance. Currently, experiments for testing drug safety are based on animal experimetns, which have the disadvantage of being time-consuming and expensive. Therefore in order to solve the above problem, a neurotoxic prediction model through an in silico experiment was suggested. In this study, the category of neurotoxicity was expanded using a unified medical language system and various related compound data were obtained based on an integrated database. The SMILES (Simplified Molecular Input Line Entry System) of the obtained compounds were converted into fingerprints and it is used as input of machine learning. The model finally predicts the presence or absence of neurotoxicity. The experiment proposed in this study can reduce the time and cost required for the in vivo experiment. Furthermore, it is expected to shorten the research period for new drug development and reduce the burden of suspension of development.

• Nuclear Engineering and Technology
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• v.55 no.3
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• pp.884-894
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• 2023

Design and safety assessment of fuel pins for application in innovative Generation IV fast reactors calls for a dedicated nuclear fuel modelling and for the extension of the fuel performance code capabilities to the envisaged materials and irradiation conditions. In the INSPYRE Project, comprehensive and physics-based models for the thermal-mechanical properties of U-Pu mixed-oxide (MOX) fuels and for fission gas behaviour were developed and implemented in the European fuel performance codes GERMINAL, MACROS and TRANSURANUS. As a follow-up to the assessment of the reference code versions ("pre-INSPYRE", NET 53 (2021) 3367-3378), this work presents the integral validation and benchmark of the code versions extended in INSPYRE ("post-INSPYRE") against two pins from the SUPERFACT-1 fast reactor irradiation experiment. The post-INSPYRE simulation results are compared to the available integral and local data from post-irradiation examinations, and benchmarked on the evolution during irradiation of quantities of engineering interest (e.g., fuel central temperature, fission gas release). The comparison with the pre-INSPYRE results is reported to evaluate the impact of the novel models on the predicted pin performance. The outcome represents a step forward towards the description of fuel behaviour in fast reactor irradiation conditions, and allows the identification of the main remaining gaps.

• Journal of the Society of Disaster Information
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• v.20 no.1
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• pp.128-137
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• 2024

Purpose: This study was conducted to investigate, through experimental methods, the efficiency of passenger movement and evacuation in the event of an emergency situation on an aircraft. Method: The experiment was conducted a total of 4 times, including 3 scenarios. The three situations were evacuation without luggage, evacuation with carry-on baggage, and evacuation with carry-on baggage and carrier. In the experiment, time was measured based on recorded video. Result: The total evacuation time was found to be approximately 1.5 times higher for the evacuation with luggage, and approximately 3.5 times higher for the evacuation with luggage and 3 carriers compared to the evacuation result in a situation where nothing was carried. As a result of applying the evacuation simulation, it was found that there was a difference from the experimental results. In particular, consideration of complex situations such as carrying out and moving carriers is considered to be a situation that requires more technical research. Conclusion: Quantitive data was obtained to determine how carry-on luggage and carrier affect evacuation.

• Journal of the Korean Society of Industry Convergence
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• v.27 no.4_2
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• pp.833-840
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• 2024

According to recent data from the Korea Meteorological Administration(KMA), the frequency of typhoons around the Korea Peninsula is almost unchanged, but the intensity is on the rise due to climate change. A typhoon that has become so powerful can cause partial or complete damage to the traffic signal structures, limiting the operation of the vehicle and causing traffic congestion. If the traffic signal structure fails to function properly due to the influence of the typhoon, not only the v ehicle operation will be disrupted, but also direct damage to the traffic signal structure will occur. In addition, if the social overhead cost of traffic congestion is included, the recovery cost caused by the typhoon will increase to an extent that it is difficult to estimate. Therefore, in this study, a wind tunnel experiment was performed by producing a wind tunnel model of an existing fixed traffic signal structure and a traffic signal structure in which signs and traffic lights are hinged. Also, The fixed and hinge structures were modeled as 3D finite elements, and wind-resistant analysis was performed by wind speed, and, wind-resistant safety of traffic signal structures were analyzed and examined through wind-resistant analyses. From the comparative analysis of the results of experiment and FE analysis, it was known that the stress reduction rate of the hinge connection structure was at least 30% compared to that of the fixed connection structure from the results of the wind tunnel experiment and FE analysis. And As a result of finite element analysis for the maximum design wind speed of 50m/s, it was found that the maximum stress generated in the existing structure exceeded all the yield stress, but the maximum stress of the hinge connection structure was within the yield stress. Finally The hinge connection structure showed a relatively large stress reduction rate as the wind speed increased and the length of the lateral beam was shorter at the same wind speed.

• Proceedings of the KIEE Conference
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• 1997.07b
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• pp.564-567
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• 1997

Various ropes used at the industrial fields can be used to experiment analyze tension tester development and also as an educational experiment tool. There fore the purpose of this paper is about rope tension tester development satisfying both safety and educational terms.

• Journal of Korean Elementary Science Education
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• v.20 no.2
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• pp.153-163
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• 2001

The purpose of this study is to improve the experiments of supplementary gravimeter in elementary school. The developing procedures of the experiments of supplementary gravimeter are as follows. First, we investigated the solutions which indicated the largest difference of the supplementary gravimeter between the dilute and concentrated solution. Second, we investigated the improvement of the supplementary gravimeter. Considering the price and safety of the chemical and easy making of the supplementary gravimeter, supplementary gravimeter of rubber-clay with the solution of the unrefined-sugar can be used effectively in experiment for elementary school.

• Proceedings of KOSOMES biannual meeting
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• 2017.04a
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• pp.133-133
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• 2017