• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.17 no.3
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• pp.181-191
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• 2007

With the 2-Butanethiol, which is an unidentified inhalation toxic material, acute inhalation toxicity was tested with SD rats. The $LC_{50}$ was evaluated to be 2,500 ppm (9.22 mg/L) or higher which falls under the criteria of acute toxicity Category 3 (500<$LC_{50}$<2,500 ppm) in the Industrial Safety and Health Act. In the subchronical inhalation toxicity test by 0, 25, 100, and 400 ppm, 6 hours a day, 5 days a week, for 13 weeks repeated exposure, though no death or particular clinical presentation was observed, in the female 25 and 400 ppm group, including weight change, and in each concentration group including 400 ppm, change of feed rate, eye stimulation, motility change in male group, and lesions in blood and blood biochemical were observed. In the internal organs weight, 25, 100, and 400 ppm groups in male and 400 ppm group in female showed significant (p<0.05) changes in kidney, liver, thymus, and lung. In the pathological tissue test, severe cortical tubular hyaline droplets were observed in the male 400 ppm group, and all male rats of 400 ppm group and 2 female individuals showed tubular degeneration/regeneration accompanied with pigmentation, showing that the target organs of inhalation exposure of 2-Butanethiol are spleen, kidney, nasal cavity, and adrenal. Through the tests, the NOEL of 2-Butanethiol was evaluated to be 25 ppm (0.092 mg/L) or less for both male and female.

• Safety and Health at Work
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• v.10 no.2
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• pp.172-179
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• 2019

Background: Workers exposed to hazards without adequate protections are at greater risk of injury and illness. Supervisor activities have also been associated with injury risk. We examined the interplay between supervisor safety support and occupational health and safety (OHS) vulnerability on workplace injury and illness. Methods: A survey was administered to 2,390 workers employed for more than 15 hrs/week in workplaces with at least five employees who had a direct supervisor. We examined the combined effects of hazard exposure with inadequate protection (OHS vulnerability) and supervisor support on workplace injury and illness, using additive interactions in log-binomial regression models. Results: OHS vulnerability and lack of supervisor support independently increased the likelihood of physical injuries at work. Crude and adjusted models showed that the risk of physical injury was at least 3.5 times higher among those experiencing both OHS vulnerability and a lack of supervisor support than individuals without OHS vulnerability and with a supportive direct supervisor. Workers who experienced vulnerability were at less risk if they had a supervisor who was supportive. Conclusion: In workplaces where workers experience one or more types of OHS vulnerability, having a supportive supervisor may play an important role in reducing the risk of injury and protecting workers.

• Safety and Health at Work
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• v.6 no.2
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• pp.85-89
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• 2015

Background: The study was designed to assess the changes in working conditions through a comparative analysis of the characteristics of working conditions in 2006 and 2010. Methods: We performed a comparative analysis of the data related to the first Korean Working Conditions Survey (KWCS) and the second KWCS in the categories of demographic characteristics, quality of labor, exposure to hazards, and health problems. Results: From our analysis of the demographic characteristics, we saw an increase in labor force participation rate of women and elderly people. As a result of the investigation with regards to working hours, the ratio of employees who worked for ${\geq}49$ hours per week was decreased and the ratio of employees who worked for ${\geq}40h/wk$ increased. As for exposure to hazards, exposure to tobacco smoke notably decreased in 2010 compared with 2006. With regards to health problems, there was a sharp increase in the number of people who complained of muscle pain in their arms and legs. Conclusion: KWCS data included many aspects of working conditions as a nationwide sample. In addition, because this is a periodic nationwide survey, the labor force, working hours, harmful factor exposure, and the change in health problems characteristics according to the flow of time could be investigated. The information comparing the main results of the first survey conducted in 2006 and the second survey conducted in 2010 obtained through this study can be used as an important base material for the establishment of the national policy.

• Journal of the Korea Safety Management & Science
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• v.6 no.4
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• pp.47-59
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• 2004

Safety in the laboratory has been a growing interest due to recent recurrences of the fatal accidents such as physical or chemical explosions. It is not easy to determine the extent to what the industrial safety and health law should be applicable to the laboratory. Most laboratory workers are not sufficiently trained and recognized for the generic features of safety and health. The actual conditions of safety and health in the laboratory are not familar with laboratory workers. Safety and health in the laboratory is unfortunately in the dead ground. Therefore, it is most imperative to secure safety in the laboratory. This study proposes a method to improve safety in the laboratory.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.21 no.3
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• pp.128-138
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• 2011

Objectives: It has been pointed out that there are problems in handling and managing chemicals due to trade secrets of Material Safety Data Sheet(MSDS). To date, some company intentionally leave out of several parts and use an inaccurate expression in MSDS. In particular, with the result of the inspection of the government and labour community, it is required that the 2nd section in MSDS included the composition and information on ingredients has to be provided with comprehensive expression to secure more reliability. Methods: Therefore, this study is aimed: 1) to recognize the current status of trade secrets of MSDS in workplaces with both domestic manufacturers of chemical products and multinational corporations; 2) to make contributions to prevention of the industrial accidents by providing the accurate information of MSDS; 3) to improve the risk communication system related with chemicals; 4) to impress workers on the importance of right of known for MSDS. With the result we analyzed the status of trade secrets in MSDS in 73 companies, such as petrochemistry production, paint production, metal processing oil production, detergent production, and international company related with chemicals, we have found that 38,150 (45.5%) have the trade secrets parts in the total number of 83,832 in MSDS. Also, based on the 288 MSDS gathered by the Occupational Safety and Health Research Institute (OSHRI) from 2005 to 2009, 41.7% of the MSDS are classified into the trade secrets. Conclusions: Therefore, to procure an assurance system of MSDS, we suggest that a MSDS picking up and checking system be legislated in the Occupational Safety and Health Act to protect workers from the unidentified chemical hazards due to the secret trade of MSDS.

• Toxicological Research
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• v.2 no.2
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• pp.63-77
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• 1986

prenatal and postanatal study on pranoprofen, as an antiinflammatory agent, was conducted by oral administration in Sprague-Dawley pregnancy rats from day 17 of gestation to day 21 of after delivery. Pranoprofen was intubated doses of 1.0, 2.5 and 5.0 mg/kg/day and dose of 5.0mg/kg/day of Indomethacin was used as positive control. After delivery, several study indexes such as length of gestation, No. of implantations, No. of live pups, No. of perinatal deaths, sex ratio and No. of malformation were checked and then all the newborns were feeded and investigated physical and behavioral changes.

• Journal of the Korea Safety Management & Science
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• v.24 no.2
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• pp.17-24
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• 2022

It was legislated in Korea that the small-sized enterprise with fewer than 50 employees should appoint at least one managing officer in order to improve safety and health of the employees since 2016. Study on the effectiveness of this legislation is hardly found, however. This study tried to evaluate effectiveness of the regulations for appointing the safety and health management officer in small-sized manufacturing companies and make suggestions to improve it. It was done by pairwise comparison between the level of safety and health achievement of 52 companies before and after the legislation. A scorecard system and questionnaires were devised for assessing the level of safety and health achievement and surveying awareness and practice of the regulation in the field. Results from quantitative and qualitative analyses performed in the study confirm that the safety and health achievement score has increased significantly after appointing the managing officer. It is also revealed that the lack of expertise and motivation of the appointed officer would yield pointless outcomes. Recommendations to make it better the effectiveness of the regulation are: to administrate requirements more strictly to be appointed as a safety and health management officer, to revise the curriculum to train the expertise of the appointed officers, and to expand financial support of the government to settle the safety and health management system.

• Journal of the Korea Safety Management & Science
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• v.18 no.2
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• pp.1-8
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• 2016

This study organizes not only the middle-long term developing plan of safety health education to put emphasis on a manufacturing industry, but also the developing plan of activating the domestic safety health education. On the basis of this study, current safety health education can be developed. To achieve a goal of implementing domestic safety health education, this study is carried out more deeply as follows.

• International Journal of Safety
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• v.10 no.1
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• pp.10-15
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• 2011

In Japan, protective measures to reduce falls from scaffolds have been strictly applied within industry safety guidelines, and such measures have significantly decreased fatal accidents due to falls from scaffolds. However, the rate of fatal accidents from falls is still high in the construction industries. In order to examine further countermeasures to reduce such falls, the Japan Ministry of Health, Labour and Welfare established a committee in our institute. That committee$\acute{i}$s work experimentally confirmed the effectiveness of using plastic sheets as a covering around scaffolds to protect against falls of construction materials (a method widely used in Japan). However, the workers fell from the space between the work platform and the plastic sheets very occasionally. Based on those results, the plastic sheets were improved for fall protection from the space, and the effect of the improved sheets was confirmed experimentally.

• Journal of the Korean Society of Safety
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• v.13 no.4
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• pp.271-278
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• 1998

Every safety and health activity relies to some extent on education and training. Through effective education and training, people learn how to recognize safety and health hazards and how to control them. Thus, in most cases education and training is the first step in an accident prevention program. In this study, we analyzed safety training course-compare with Industrial Safety & Health Act, KISCO and KISA's rules,-and applied to workplace. In the safety training of workplace on the ground of the Industrial Safety & Health Act, the ratio of periodic employee refresher training to the total training subjects is only 25% and it of supervisor training is 16.7%. The ratio of training implemented in workplace about Knowledge, Skill, Attitude is as follows Periodic update training ; 15.1% : 7.5% : 64.2% New employees training ; 15.7% : 5.9% : 58.8% Job-change training ; 32.6% : 23.2% : 39.5% Specific safety & health training : 34.8% : 8.7% : 45.6%.