• Animal Bioscience
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• 제34권3_spc호
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• pp.385-392
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• 2021

Objective: The present study was conducted to investigate the effects of lycopene on growth performance, abdominal fat deposition, serum lipids levels, activities of hepatic lipid metabolism related enzymes and genes expression in broiler chickens. Methods: A total of 256 healthy one-day-old male Arbor Acres broiler chicks were randomly divided into four groups with eight replicates of eight birds each. Birds were fed basal diet supplemented with 0 (control), 100, 200, and 400 mg/kg lycopene, respectively. Results: Dietary 100 mg/kg lycopene increased the body weight at 21 day of age compared to the control group (p<0.05). Compared to the basal diet, broilers fed diet with 100 mg/kg lycopene had decreased abdominal fat weight, and broilers fed diet with 100 and 200 mg/kg lycopene had decreased abdominal fat percentage (p<0.05). Compared to control, diets with 100, 200, and 400 mg/kg lycopene reduced the levels of total triglyceride and total cholesterol in serum, and diets with 100 and 200 mg/kg lycopene reduced the level of serum low density lipoprotein cholesterol (p<0.05). The activity of fatty acid synthase (FAS) in 400 mg/kg lycopene treated broilers and the activity of acetyl-CoA carboxylase (ACC) in 100, 200, and 400 mg/kg lycopene treated broilers were lower than those fed basal diet (p<0.05). Lycopene increased the mRNA abundance of adenosine monophosphate activated protein kinase α (AMPK-α), whereas decreased the mRNA abundance of sterol regulatory element-binding protein 1, FAS, and ACC compared to the control group (p<0.05). Conclusion: Dietary lycopene supplementation can alleviate abdominal fat deposition and decrease serum lipids levels, possibly through activating the AMPK signaling pathway, thereby regulating lipid metabolism such as lipogenesis. Therefore, lycopene or lycopene-rich plant materials might be added to poultry feed to regulate lipid metabolism.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제27권1호
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• pp.45-51
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• 2021

Purpose: Problems related to the elderly's daily life, such as social isolation and absence of a place to go, are already widely recognized, but there are few domestic studies or support policies for this, and the elderly leisure welfare facilities provided by the state do not fully support the elderly's daily life. There are studies related to the elderly's neighborhood environment and facilities, which can be seen as the third place for the elderly in Korea, but these are mostly quantitative studies. In order to talk about the third place for daily support for the elderly in Korea, a detailed study of the use cases of the third place in Korea is needed. This study analyzes the third place of the elderly in Korea and discovers the characteristics and components. Based on the detailed analysis of the third place of the elderly, the characteristics of the third place of the elderly in Korea and the elements constituting it are found to be able to represent the specific necessary environment of the third place of the elderly. Methods: The research targets include 'A Mill' (located in Jungnang-gu, Seoul), and 'Roadside in front of Villa B'(located in Dongdaemun-gu, Seoul), 'C-dong roadside park'(located in Dobong-gu, Seoul) within the range of repeated observations and meetings among the places used as a third place for the elderly was selected. The site survey consisted of in-depth interviews, observational surveys, and participatory observations. In-depth interviews were held for a total of 5 months, from October to December 2019 and from April to May 2020. Results: As a result, a total of 11 characteristics (adjacent to the residence, an open place, an independent space, a comfortable place to stay, a pleasant space, safety is guaranteed, a place that has been operated for a long time, a place that can be used autonomously, a place where social exchange occurs, No financial burden, fun activities) was discovered. Implications: This study is significant in that unlike the existing studies focusing on the use behavior of established institutions or facilities, the elderly identified the necessary environment through their own created places.

• 셀메드
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• 제11권3호
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• pp.13.1-13.9
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• 2021

Background and Objective: Nux-vomica based traditional Unani formulation, Habb-e-Azaraqi (HAZ) is an important drug used by Unani physicians since several decades. It possesses Muqawwi-i-A'sab (nervine tonic), Muharrik-i-A'sab (nervine stimulant) properties and is an effective treatment option for diseases like Laqwa (facial palsy), Falij (paralysis), Niqris (gout) and Waja'al-Mafasil (arthritis) etc. The aim of the study is to access and provide information of HAZ for its TLC, HPTLC Fingerprinting defining its clear qualitative perspective and acute oral toxicity evaluation for its safety assessment which was not done earlier, thus contributing in the field of research. Materials and Methods: The chief ingredient, nux-vomica was detoxified as per method mentioned in Unani Pharmacopeia before its use in formulation. TLC and HPTLC was developed under four detection system i.e., UV 366nm, UV 254nm, exposure to iodine vapours and after derivatization with anisaldehyde sulphuric acid. Acute toxicity studies were performed as per OECD Guidelines 425 at a limit dose of 2000 mg/kg. Observations were done for signs of toxicity, body weight, and feed consumption at regular intervals followed by haematological and biochemistry evaluation. Results: The generated data proved the authenticity and established the TLC and HPTLC profile of the formulation. Acute toxicity revealed no significant differences in HAZ-treated animals with respect to body weight gain, feed consumption, haematology, clinical biochemistry evaluation. No significant gross pathological observation was noticed in necropsy. Conclusion: Data of the present study is substantial and scientific proof of HAZ in terms of standardization and toxicity study that can be utilize in future research activities.

• 지질공학
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• 제31권2호
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• pp.135-148
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• 2021

굴착 전 지반조사 결과를 활용한 지반함몰 위험등급 분류는 시공 과정에서 들어나는 인자들에 따라 평가 결과가 다르게 나타날 수 있다. 본 연구에서는 기존 연구에서 제안된 굴착 전 지반조사 결과를 활용한 지반함몰 위험등급 분류 방법을 현장상황을 고려하여 보정하는 방법을 제시하였다. 굴착 진행 중 지하수위는 차수공법의 적용 여부나 시공 상태에 따라 유출되는 정도가 시공 전 예측결과와 다르게 나타난다. 굴착 중 급격한 지하수위 하강은 압밀이나 압축 등의 체적 감소로 지반함몰을 유발하고 집중 호우 등에 의한 수위 상승은 굴착 저면의 히빙이나 보일링을 발생시켜 지반함몰 위험도를 높인다. 굴착 중 흙막이 벽체의 과도한 변위나 지반침하는 지반함몰의 원인이 될 수 있으며, 매설된 관로의 파손을 야기하여 지반함몰 위험도를 높인다. 본 연구에서는 굴착 중 지하수 변동 및 유출상태, 지반변위, 흙의 종류 등을 고려하여 지반함몰 영향인자를 재평가하는 방법을 제안하였다. 최종적으로 지반함몰 평가의 영향인자를 5개 카테고리의 12개 영향인자로 평가할 수 있도록 개선하였다.

• 한국학교ㆍ지역보건교육학회지
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• 제22권4호
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• pp.49-60
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• 2021

Objectives: Laboratories have various latent physical, chemical, biological, and ergonomical factors according to the diversification and fusion of research and development activities. This study aims to investigate the chemical exposure concentrations of college laboratories and evaluate their health risks, and use them as basic data to promote the health of college students. Methods: The sampling and analysis of harmful chemicals in the air in laboratories were performed using Method 1500 of the U.S. National Institute for Occupational Safety and Health (NIOSH)의 Method 1500. The harmful chemicals in the laboratories were divided into carcinogenic and non-carcinogenic chemicals. Risk assessment was performed using the cancer risk (CR) for carcinogenic chemicals and using the hazard index (HI) for non-carcinogenic chemicals. Results: The harmful chemicals in college laboratories consisted of acetone, diethyl ether, methylene chloride, n-hexane, ethyl acetate, chloroform, tetrahydrofuran, toluene, and xylenes. They showed the highest concentrations in laboratories A (acetone 0.001~2.34ppm), B (chloroform 0.95~6.35ppm), C (diethyl ether 0.08~8.68ppm), and D (acetone 0.07~14.96ppm). The risk assessment result for non-carcinogenic chemicals showed that the HI of methylene chloride was 2.052 for men and 2.333 for women, the HI of N-hexane was 4.442 for men and 5.05 for women. Thus, the HI values were higher than 1. The risk of carcinogenic chemicals is determined by an excess cancer risk (ECR) value of 1.0×10^-5, which means that one in 100,000 people has a cancer risk. The ECRs of chloroform exceeded 1.0×10^-5 for both men and women, indicating the possibility of cancer risk. Conclusion: College laboratories showed the possibility of non-carcinogenic health risks for methylene chloride, n-hexane, tetrahydrofuran (THF), toluene, and xylenes, and carcinogenic health risks for chloroform, methylene chloride. However, this study used the maximum values of measurements to determine the worst case, and assumed that the subjects were exposed to the corresponding concentrations continuously for 8 hours per day for 300 days per year. In consideration of the nature of laboratory environment in which people are intermittently exposed, rather than continuously, to the chemicals, the results of this study has an element of overestimation.

• 지역연구
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• 제38권1호
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• pp.21-32
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• 2022

본 연구의 목적은 두 가지이다. 첫째, 공유 모빌리티 중 사회적 갈등이 가장 첨예한 공유택시 플랫폼을 개발·실증하는데 있다. 이를 위해 기존 택시 서비스에 대한 소비자의 인식을 중요·만족도분석(IPA)를 활용해 분석하여 플랫폼 개발을 위한 함의를 도출하였다. 중요·만족도분석(IPA)을 통해 분석한 결과 유지관리영역에는 비정상적 영업활동과 안심 서비스가 중점개선영역에는 안전한 승차감과 손쉬운 승차가 도출되었다. 개선대상영역에는 이용 요금 수준과 운전자 정보제공 등 안전성이, 과잉투자영역에는 친절한 응대와 내외부 청결도가 각각 도출되었다. 본 연구의 두 번째 목적은 공유택시 서비스 플랫폼에 대해 이용자들의 부여하는 가치를 조건부가치추정법(CVM)을 활용해 추정하는데 있다. 본 연구를 통해 개발한 공유택시 플랫폼의 실증 서비스의 가치를 추정한 결과 평균 지불용의액(WTP)은 연간 가구당 3,621원으로 나타났으며, 해당 서비스를 김해시 전역으로 확산할 경우 평균 지불용의액이 2,515원/가구당/연간으로 나타났다. 실증서비스에 대한 지불의사에 비해 김해시 전역 확산 사업에 대한 지불의사는 69.5% 수준에 그쳤다. 이는 불특정 다수에 대한 서비스 확산, 공간적 확대에 따른 서비스 질 우려 등이 복합적으로 작용한 결과이다. 지속적인 실증을 통해 데이터를 구축하고, 이를 기반으로 서비스 고도화하여 확산을 위한 로드맵을 꼼꼼하게 구축할 필요가 있음을 시사하는 대목이다.

• International Journal of Computer Science & Network Security
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• 제22권1호
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• pp.331-339
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• 2022

The global process of transition from industrial to information society, as well as socio-economic changes taking place in Ukraine, require significant changes in many areas of state activity. It is especially connected with the reforms in the sphere of education. Today, national programs provide for the development of education on the basis of new progressive concepts, the introduction of the educational process of new pedagogical technologies and scientific achievements, the creation of a new system of information education, entrance of Ukaine into the transcontinental computer information system. Information technologies are qualitatively changing the key resources of development: this is no longer a space with fixed production, but primarily mobile finance and intelligence. They have a direct impact on the formation of personal growth, professional content and self-organization, emotional and psychological maturity and consciousness, and so on. One of the main factors in ensuring the stability and social education of the country's citizens is the culture of security, the formation and development of which is an urgent problem today. Comprehensive and systematic development of security culture will significantly increase the readiness of the population, the level of environmental, labor and patriotic education, reduce human losses, material damage from emergencies. Ecological education can be carried out more successfully only gradually and in accordance with the socio-psychological periods of one's development: kindergarten - school - college - university. The creation of such a system of environmental education should be enshrined as the basis of state environmental policy as a constitutional norm with the usage of information technology. Graduates of universities, who are the future of our country, after mastering the skills of basic environmental education must have a high level of environmental culture, which is, in turn, part of general human culture, and investigate environmental issues from the standpoint of their profession. It is known that with the help of environmental education the collective intelligence of society is formed, which can predict human activities and processes occurring in nature, and in some way to help with the elimination of crises. It is through environmental education that another system of human values is being formed, which places great emphasis on intangible wealth and solidarity, and great responsibility of humanity for the ecological state of the native country; provides a higher standard of living as a result of sustainable development, through the introduction of information technology in this system. To improve the quality of life, we need better knowledge, which must be implemented through information technology at the international level.

• 광물과 암석
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• 제35권1호
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• pp.75-81
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• 2022

글로벌 광물에너지자원 분야 수요공급에서 중국의 자원조사탐사개발과 자원경제 정책이 한국의 산업 경쟁력과 밀접하므로, 중국의 자원관련 활동을 분석하는 것은 국내외 자원개발 전략수립에 매우 중요한 사항이라고 할 수 있다. 중국은 2020년에 광물자원관련 법제 개정과 표준을 정하면서 광물자원 탐사개발과 매장량 관리의 효율성을 기하고 있다. 중국 자연자원부는 국가광물자원계획(2021~2025년)의 수립을 통해 국가차원의 목표와 전략을 달성하고자 하며, 각 급 지방정부에서도 지역광물자원계획을 수립하여 시행하고 있다. 이를 통해, 지질광물탐사 활동 감독 및 관리가 강화되었고, 지질광물 탐사개발분야 산업의 생산 관리의 안전성이 강화되었다. 중국은 고품질의 지질탐사, 측량 및 지도 작성 지침개발을 통해, 중국의 지질광물탐사개발 수준을 향상시키고 광업 감독관리 체계 강화를 기하고 있다. 중국의 고체광물자원 매장량분류와 석유가스광물자원 매장량분류 등의 광물자원 표준 마련으로 중국내 새로운 매장량 관리 표준체계가 구축되어 과학적인 광물자원 자원량과 매장량의 파악 및 합리적 관리와 이용 등이 개선될 것으로 여겨진다.

• 한국의료질향상학회지
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• 제28권1호
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• pp.14-33
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• 2022

Purpose: To examine whether the Patient Experience Assessment (PEA) has led to perceptible changes at the ground level of health care, as a way of evaluating PEA as a policy intervention for quality improvement. Methods: Four focus group discussions (FGDs) were conducted, each comprising six to eight participants who were employees responsible for patient experience at their respective hospitals. The primary focus of the FGDs was on questions such as: 1) How do hospitals respond to PEA? 2) What significant changes were observed after the implementation of PEA? 3) What were the unintended consequences of implementing PEA, if any? 4) What areas of improvement have been identified for maximizing the potential of PEA? Results: Two broad themes emerged out of the FGDs: changes observed post implementation of PEA, and areas for improvement of PEA. Four significant changes were reported by participants: changes in perception and attitude regarding patient experience in hospital employees, increased active involvement by the hospital leadership, enhanced efforts to improve patient experience, and increased cooperation between such activities. Furthermore, eight areas of improvement were identified, which have been grouped in three categories: improving the process of data collection for PEA, introducing additional catalysts to facilitate further changes, and paying attention to structure- and patient-level constraints that must be addressed in parallel. Conclusion: The implementation of PEA led to perceptible changes within hospitals, which implies that it can serve as an effective catalyst for improving patient experience. A number of areas of improvement that would aid in maximizing the potential of PEA were also identified.

• 한국시뮬레이션학회논문지
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• 제31권1호
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• pp.11-18
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• 2022

최근 공공장소 및 시설에서 범죄예방 및 시설 안전을 목적으로 영상정보 기반의 인체의 행위를 분류하는 연구가 활발히 진행되고 있다. 이러한 인체 행위분류의 성능을 향상하기 위해서 대부분의 연구는 전이학습 기반의 딥러닝을 적용하고 있다. 그러나 딥러닝의 기반이 되는 중추 네트워크 모델(Backbone Network Model)의 수가 증가하고 아키텍처가 다양해짐에도 불구하고, 소수의 모델만 사용하는 분위기 때문에 운용목적에 적합한 중추 네트워크 모델을 찾는 연구는 미흡한 실정이다. 본 연구는 영상정보를 기초로 인체 행위를 분류하는 인공지능 모델을 개발하기 위해 최근에 개발된 5가지의 딥러닝 중추 네트워크 모델을 대상으로 전이학습을 적용하고 각 모델의 정확도 및 학습효율 측면에서 비교 및 분석하여 가장 효율이 높은 모델을 제안하였다. 이를 위해, 기본적인 인체 행위가 아닌 운동 종목 기반의 활동적이고 신체접촉이 높은 12가지의 인체 활동을 선정하고 관련된 7,200개의 이미지를 수집하였으며, 5가지의 중추 네트워크 모델에 총 20회의 전이학습을 균등하게 적용하고 학습과정과 결과성능을 통해 인체 행위를 분류하는데 적합한 중추 네트워크 모델을 정량적으로 비교 및 분석하였다. 그 결과 XceptionNet 모델이 학습 및 검증 정확도에서 0.99 및 0.91로, Top 2 및 평균 정밀도에서 0.96 및 0.91로 나타났으며 학습 소요시간은 1,566초, 모델용량의 크기는 260.4MB로 정확도와 학습효율 측면에서 다른 모델보다 높은 성능이 나타남을 확인할 수 있었다. 이러한 결과는 전이학습을 적용하여 인체 행위분류를 진행하는 다양한 연구 분야에 활용되기를 기대한다.