• Title/Summary/Keyword: s-INS

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A NOTE ON TYPES OF NOETHERIAN LOCAL RINGS

  • Lee, Kisuk
    • Bulletin of the Korean Mathematical Society
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    • v.39 no.4
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    • pp.645-652
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    • 2002
  • In this note we investigate some results which concern the types of local rings. In particular it is shown that if the type of a quasi-unmixed local ring A is less than or equal to depth A + 1, and $\hat{A}_p$ is Cohen-Macaulay for every prime $p\neq\hat{m}$, then A is Cohen-Macaulay. (This implies the previously known result: if A satisfies $(S_{n-1})}$, where n is the type of a .ins A, then A is Cohen-Macaulay.)

Cytoprotective Effect of Lespedeza Cuneata Extract on Glucose Toxicity (야관문(夜關門)의 포도당 독성에 대한 세포 보호 효과)

  • Choi, Jeong-Sik;Cho, Chung-Sik;Kim, Cheol-Jung
    • The Journal of Korean Medicine
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    • v.31 no.4
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    • pp.79-100
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    • 2010
  • Objective: Production of ROS from glucose toxicity results in injury of pancreatic $\beta$-cells in diabetes models. This study was undertaken to examine the influence of Lespedeza Cuneata extract (LCE) on cytoprotective effects on glucose toxicity, insulin secretion and gene expression in RIN-m5F cells. Methods: First, we measured LCE's antioxidant activity by DPPH free radical-scavenging activity and SOD activity. After the various concentrations of LCE were added to the RIN-m5F cells, we measured cell viability with glucose stimulation by MTT assay and glucose-stimulated insulin secretion. We analyzed gene expression with Agilent whole mouse genome 44K oligo DNA microarray and searched for related pathways in KEGG (Kyoto Encyclopedia of Genes and Genomes). Lastly we measured INS-1, INS-2, INS-R, IRS-1, IRS-2, IRS-3, GLP-1R, and GLP-2R mRNA expression by real time RT-PCR. Results: Free radical-scavenging activity, SOD activity and insulin secretion increased dependent on LCE concentration, but LCE did not show considerable cytoprotective effect on RIN-m5F cells. More than twice expressed gene was 6362 in Oligo DNA chip. In KEGG, the most related pathway was the metabolic pathway. In the insulin signaling pathway, up expressed genes were Irs1, Mapk8, Akt1, and Lipe and down expressed genes were Rhoq, Fbp2, Prkar2b, Gck, and Prkag1. In real time RT-PCR, IRS-2, and IRS-3 expression increased significantly compared to the control group on LCE $12{\mu}g/m{\ell}$ concentration and GCK expression decreased significantly compared to the control group. Conclusions: These results show that LCE encourages insulin secretion and insulin metabolism by complicated gene mechanisms. Further mechanism study and clinical study seem to be necessary about Lespedeza Cuneata.

Observability Analysis of a Vision-INS Integrated Navigation System Using Landmark (비전센서와 INS 기반의 항법 시스템 구현 시 랜드마크 사용에 따른 가관측성 분석)

  • Won, Dae-Hee;Chun, Se-Bum;Sung, Sang-Kyung;Cho, Jin-Soo;Lee, Young-Jae
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.38 no.3
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    • pp.236-242
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    • 2010
  • A GNSS/INS integration system can not provide navigation solutions if there are no available satellites. To overcome this problem, a vision sensor is integrated with this system. Since generally a vision aided integration system uses only feature point to compute navigation solutions, it has a problem in observability. In this case, additional landmarks, which is priory known points, can improve the observability. In this paper, the observability is evaluated using TOM/SOM matrix and Eigenvalues. There are always the observability problems in the feature-point-only case, but the landmark-use case is fully observable after the $2^{nd}$ update time. Consequently the landmarks ensure full observability, so the system performance can be improved.

RTN4 3'-UTR Insertion/Deletion Polymorphism and Susceptibility to Non-Small Cell Lung Cancer in Chinese Han Population

  • Lu, De-Yi;Mao, Xu-Hua;Zhou, Ying-Hui;Yan, Xiao-Long;Wang, Wei-Ping;Zheng, Ya-Biao;Xiao, Juan-Juan;Zhang, Ping;Wang, Jian-Guo;Ashwani, Neetika;Ding, Wei-Liang;Jiang, Hua;Shang, Yan;Wang, Ming-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5249-5252
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    • 2014
  • Nogo protein, encoded by gene reticulon-4 (RTN4), includes three major isoforms by different splicing, named Nogo-A Nogo-B and Nogo-C. Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The CAA insertion/deletion polymorphism (rs34917480) within RTN4 3'-UTR has been reported to be associated with many cancer types. In order to investigate the relationship between this polymorphism and susceptibility to non-small cell lung cancer (NSCLC) in the Chinese population, we conducted the present case-control study including 411 NSCLC patients and 471 unrelated healthy controls. The genotype distributions were significantly different between cases and controls (p=0.014). We found that the del allele could significantly increase NSCLC risk (ins/ins vs ins/del: p=0.007, OR 1.46, 95%CI=1.11-1.93; dominant model: p=0.004, OR 1.47, 95%CI=1.13-1.92 and allele model: p=0.008, OR 1.35, 95%CI=1.08-1.67). This association was stronger in participants over 60 years old, males and smokers. We therefore conclude that the CAA insertion/deletion polymorphism (rs34917480) contributes to non-small cell lung cancer risk in Chinese population. Age, sex and environmental exposure are also related to carcinogenic effects of rs34917480.

Growth of Green Pepper(Capsicum annuum L.) in a Plastic Greenhouse Covered with Anti-dropping Plasma Film (방적성 Plasma 처리 필름으로 피복된 플라스틱온실의 풋고추 생육)

  • Chun, Hee;Kim, Kyung-Je;Kim, Jin-Young;Kim, Hyun-Hwan;Lee, Si-Young
    • Journal of Bio-Environment Control
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    • v.9 no.3
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    • pp.156-160
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    • 2000
  • The Plasma film treated with a high electric voltage was developed to enhance flow down of condensation drops on inside plastic film. Arch type greenhouse framed with iron pipe of 25mm diameter defand 1.5mm thickness were covered with either the developed plasma film or surfactant film(control). Green pepper seedlings raised for 40 days in plug trays were transplanted at a density of 110cm by 30cm in each greenhouse. The mount of condensational water on film surface, generated by 7$0^{\circ}C$ water bath chimney systems and flew down, was collected and measured. The amount of collected water after 150 minutes was 2.56 mL.100c $m^{-2}$ and 0.94mL.100c $m^{-2}$ , respectively, in the plasma film and surfactant film-covered greenhouses. The amount of condensational water drops attached on the cover at 08:20 a.m. at 60 days filter covering was 0.34mL.100c $m^{02}$ and 0.32mL.100c $m^{-2}$ , respectively, in the plasma film- and surfactant film-covered greenhouses. Solar irradiance transmitted into greenhouse was 2.0% higher in the greenhouse covered with the plasma film tan that in the greenhouse covered with the surfactant film. Air temperature in the plasma film-covered greenhouse was higher than the surfactant film-covered greenhouse by 0.5$^{\circ}C$. However, there was no difference in relative humidity between the two greenhouse. Plant height, leaf area, dry weight and early yield showed no significant differences.s.

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Fabrication of Polysilicon Microstructures Using Vapor-phase HF Etching and Annealing Techniques (HF 증기상 식각과 열처리를 이용한 다결정 규소 미세 구조체의 제작)

  • Park, K.H.;Lee, C.S.;Jung, Y.I.;Lee, J.Y.;Lee, Y.I.;Choi, B.Y.;Lee, J.H.;Yoo, H.J.
    • Proceedings of the KIEE Conference
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    • 1995.11a
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    • pp.603-605
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    • 1995
  • We present a novel method. to fabricate surface micromachined structures without their sticking on the substrate. An anhydrous HF/$CH_3OH$ vapor-phase etching (VPE) of sacrificial $SiO_2$ layers was employed to release 0.5-2 {\mu}m$ thick polysilicon cantilevers. The fabricated structures were observed using scanning electron microscope and 3-dimensional optical microscope. The results show that we can successfully make cantilever beams up to 1200{\mu}m$ long without sticking. Annealing effects on residual stress of polysilicon microstructures were also investigated. Anneal ins at 1100$^{\circ}C$ for 1 hour was found to be effective to release the residual stress of the polysilicon microstructures. These VPE and anneal ins techniques will be useful in surface micromachining technologies.

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Development of roadside image data acquisition system for road facility management (도로 시설물 관리를 위한 노변 영상 취득 시스템 개발에 관한 연구)

  • Kim, Moon-Gie;Sung, Jung-Gon
    • Proceedings of the KSRS Conference
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    • 2008.03a
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    • pp.7-13
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    • 2008
  • 본 연구에서 개발한 노변 영상(roadside image) 취득 시스템은 효율적으로 도로 시설물들을 관리하기 위함이다. 복잡하고 긴 구간의 도로에 존재하는 도로 시설물을 인력을 사용하여 조사하기에는 많은 시간과 비용이 소요된다. 도로를 따라 움직이는 차량을 이용하는 경우에는 적은 인원과, 단시간에 노변에 설치된 시설물 등의 현황과 상태를 조사 할 수 있으며 도로 주변의 다양한 정보를 알 수가 있다. 또한, 차량에 장착된 GPS/INS 통합시스템을 사용하여 해당 영상의 정확한 위치 정보를 획득 할 수 있다. 그러나 선명한 영상을 취득하기 위해서 야외의 다양한 조건을 만족시키는 카메라와 렌즈의 선정이 중요하며, 이에 따른 동기화 장치(synchronization device)와 영상 획득 프로그램의 개발이 필요하다. 본 논문에서는 경기도 고양시를 대상으로 시험을 실시하였으며, 현재 시판되고 있는 최신의 다양한 종류의 카메라와 렌즈를 차량에 장착한 후 영상을 취득하여 연구에 적합한 하드웨어를 선정하였다. 또한 동기화 장치를 사용하여 DMI(Distance Measuring Instrument)에서 발생되는 트리거 신호를 입력받아 일정한 거리마다 영상을 취득하는 S/W와 동기화 장치의 성능을 테스트하였다. 취득된 노변 영상의 위치 정확도를 테스트하기 위해 DGPS 방법을 이용하여 후처리 하였으며, 레벨 2수준의 교통주제도에 차량의 이동궤적과 도로의 선형을 중첩하여 육안으로 비교 분석하였다. 취득된 노변 영상을 분석하여 지상 모니터링 분야에서 도로 주변 시설물의 변화 탐지에 이용이 가능한 대상 시설물 목록을 선정하였으며 매우 효율적으로 도로의 유지관리에 활용이 가능할 것으로 기대된다.

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MEASUREMENT AND SIMULATION OF EQUATORIAL IONOSPHERIC PLASMA BUBBLES TO ASSESS THEIR IMPACT ON GNSS PERFORMANCE

  • Tsujii, Toshiaki;Fujiwara, Takeshi;Kubota, Tetsunari;Satirapod, Chalermchon;Supnithi, Pornchai;Tsugawa, Takuya;Lee, Hungkyu
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.6_2
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    • pp.607-613
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    • 2012
  • Ionospheric anomaly is one of the major error sources which deteriorate the GNSS performance. In the equatorial region, effects of the ionospheric plasma bubbles are of great interest because they are pretty common phenomena, especially in the period of the high solar activity. In order to evaluate the GNSS performance under circumstance of the bubbles, an ionospheric scintillation monitor has been developed and installed in Bangkok, Thailand. Furthermore, a model simulating the ionospheric delay and scintillation due to the bubbles has been developed. Based on these developments, the effects of the simulated plasma bubbles are analyzed and their agreement with the real observation is demonstrated. An availability degradation of the GPS ground based augmentation system (GBAS) caused by the bubbles is exampled in details. Finally, an integrated GPS/INS approach based on the Doppler frequency is proposed to remedy the deterioration.

Improving Covariance Based Adaptive Estimation for GPS/INS Integration

  • Ding, Weidong;Wang, Jinling;Rizos, Chris
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • v.1
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    • pp.259-264
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    • 2006
  • It is well known that the uncertainty of the covariance parameters of the process noise (Q) and the observation errors (R) has a significant impact on Kalman filtering performance. Q and R influence the weight that the filter applies between the existing process information and the latest measurements. Errors in any of them may result in the filter being suboptimal or even cause it to diverge. The conventional way of determining Q and R requires good a priori knowledge of the process noises and measurement errors, which normally comes from intensive empirical analysis. Many adaptive methods have been developed to overcome the conventional Kalman filter's limitations. Starting from covariance matching principles, an innovative adaptive process noise scaling algorithm has been proposed in this paper. Without artificial or empirical parameters to be set, the proposed adaptive mechanism drives the filter autonomously to the optimal mode. The proposed algorithm has been tested using road test data, showing significant improvements to filtering performance.

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Reduced Order Luenberger State Observer Design for Lateral Direction Approach Control of Aircraft (항공기의 횡방향 접근 제어를 위한 축소차수 상태관측기 설계)

  • Lee, Byung-Seok;Heo, Moon-Beom;Nam, Gi-Wook;Park, Hyeong-Taek
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.20 no.2
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    • pp.18-25
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    • 2012
  • The availability of the GPS signal has been expanded greatly in the field of society overall through the development and construction of the GNSS(Global Navigation Satellite System). Furthermore, in the military, aviation and field of space, the GPS signal is applied widely through the combination of INS consisting of gyroscope and accelerometer, IMU, AHRS with the addition of magnetic sensor. Particularly, the performance of these equipments or sensors is very important with GPS and PAR(Precision Approach Radar) in the flight control of the aircraft. This paper deals with MATLAB simulation and ROLSO(Reduced Order Luenberger State Observer) design to reduce the load of system and realize the stable lateral direction approach control in an appropriate time for reduction of the horizontal error which is importantly considered while an aircraft lands instead of the FOLSO(Full Order Luenberger State Observer) using all measurement values. Consequently, ROLSO is expected to be used for the aircraft's attitude control in the aircraft landing causing the burden to the pilots.