• 제목/요약/키워드: rplK

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Antimutagenic Effects of Juices from the Peppers in Salmonella Assay System

  • Park, Kun-Young;Kweon, Young-Mi;Rhee, Sook-Hee
    • 한국식품영양과학회지
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    • 제24권3호
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    • pp.440-445
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    • 1995
  • The antimutagenic effects of juices from green pepper(GP), red pepper leaf(RPL), red pepper(RP) and sweet pepper(SP) were examined by the Ames method using Salmonella typhimurium TA100. The juice supernatants of GP, RPL and RP showed antimutagenic activities against afltoxin B1(AFB1) in Salmonella typhimurium TA 100. The juice supermatants of GP and RPL also exhibited the inhibitory effects(p<0.05) to the mutagenicities induced by N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) and 4-nitro-quinoline-1-oxide(4-NQO). The juice of RP showed antimutagenic activities against indirect mutagen of AFB1, however, the activity was reduced at higher concentration(5.0%), furthermore, as the adding concentration of sample increased to 5.0%, it exhibited slight comutagenicith on direct mutagen of MNNG. Theantimutagenic activities of GP and RPL juices were reduced significantly after heating at 100℃ for 20min, supposing that the antimutagenic compound(s) in the juices were heat labile.

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멀티 싱크 기반 IoT 네트워크에서 불필요한 경로 업데이트 문제와 두 가지 해결 기법 (Two Solutions for Unnecessary Path Update Problem in Multi-Sink Based IoT Networks)

  • 이성원;강현우;유홍석;정용환;김동균
    • 한국통신학회논문지
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    • 제40권12호
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    • pp.2450-2460
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    • 2015
  • 최근 IoT(Internet of Things)에 대한 관심이 증가함에 따라, IoT의 특징을 고려한 새로운 프로토콜에 대한 연구 및 표준화가 진행되고 있다. 그 중 RPL(IPv6 for Low-Power Lossy Network)는 IoT를 위해 표준화된 라우팅 프로토콜이다. RPL은 싱크 노드로부터 네트워크 전체로 플러딩 되는 DIO(DODAG Information Object) 메시지를 사용하여 라우팅 경로를 생성 및 관리한다. 그러나, 대규모 네트워크에서는 네트워크 전체에 DIO 메시지를 전파하는 데 많은 시간이 소모될 뿐만 아니라 싱크 노드 주변에서 데이터 패킷의 병목 현상이 발생하게 된다. 이러한 문제를 해결하기 위해서 라우팅 오버헤드 및 병목 현상을 감소시킬 수 있는 멀티 싱크 기반 접근법이 널리 활용된다. 이 논문에서는 멀티 싱크 기반 IoT 네트워크에 RPL 프로토콜을 적용 시 발생할 수 있는 '불필요한 경로 업데이트 문제'를 정의하고, 선택적인 경로 업데이트를 위한 2가지 기법인 Routing Metric based Path Update Decision 기법과 Immediate Successor based Path Update Decision 기법을 제안한다.

Improved Routing Metrics for Energy Constrained Interconnected Devices in Low-Power and Lossy Networks

  • Hassan, Ali;Alshomrani, Saleh;Altalhi, Abdulrahman;Ahsan, Syed
    • Journal of Communications and Networks
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    • 제18권3호
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    • pp.327-332
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    • 2016
  • The routing protocol for low-power and lossy networks (RPL) is an internet protocol based routing protocol developed and standardized by IETF in 2012 to support a wide range of applications for low-power and lossy-networks (LLNs). In LLNs consisting of resource-constrained devices, the energy consumption of battery powered sensing devices during network operations can greatly impact network lifetime. In the case of inefficient route selection, the energy depletion from even a few nodes in the network can damage network integrity and reliability by creating holes in the network. In this paper, a composite energy-aware node metric ($RER_{BDI}$) is proposed for RPL; this metric uses both the residual energy ratio (RER) of the nodes and their battery discharge index. This composite metric helps avoid overburdening power depleted network nodes during packet routing from the source towards the destination oriented directed acyclic graph root node. Additionally, an objective function is defined for RPL, which combines the node metric $RER_{BDI}$ and the expected transmission count (ETX) link quality metric; this helps to improve the overall network packet delivery ratio. The COOJA simulator is used to evaluate the performance of the proposed scheme. The simulations show encouraging results for the proposed scheme in terms of network lifetime, packet delivery ratio and energy consumption, when compared to the most popular schemes for RPL like ETX, hop-count and RER.

우주왕복선 액체로켓엔진 작동의 최적출력제어 시뮬레이션 (Optimal Output Feedback Control Simulation for the Operation of Space Shuttle Main Engine)

  • 차지형;고상호
    • 한국추진공학회지
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    • 제20권3호
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    • pp.37-53
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    • 2016
  • 본 논문에서는 다단 연소방식의 액체로켓엔진인 우주왕복선 주 엔진(Space Shuttle Main Engine, SSME)의 제어 알고리즘을 다룬다. 이를 위해 SSME의 각 구성품들을 기준으로 크게 7가지 분류로 나누어 구성하여 수학적 모델링을 하였으며 순항상태 추력을 기준으로 Rated Propulsion Level (RPL)에 따른 정상상태 작동점을 구하였다. 폐루프 시스템을 위하여 순항상태인 RPL 104% 조건에서의 선형모델을 이용하여 최적 출력피드백 LQR 제어기 설계를 하였으며 시뮬레이션을 통해 제어기의 성능을 검증하였다.

Evaluation of Antioxidant and Antimicrobial Activities of Ethanol Extracts of Three Kinds of Strawberries

  • Seleshe, Semeneh;Lee, Jong Seok;Lee, Sarah;Lee, Hye Jin;Kim, Ga Ryun;Yeo, Joohong;Kim, Jong Yea;Kang, Suk Nam
    • Preventive Nutrition and Food Science
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    • 제22권3호
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    • pp.203-210
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    • 2017
  • The antioxidant and antimicrobial activities of three kinds of strawberry ethanol extracts from Robus corchorifolius L. f. (RCL), Rubus parvifolius L. var. parvifolius (RPL), and Duchesnea chrysantha Miq. (DCM) were investigated. The RPL was highest (P<0.05) in phenolic, flavonoid, and anthocyanin contents. 2,2-Diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging activities of RPL and DCM extracts were higher than that of RCL (P<0.05). Hydrogen peroxide scavenging activity of RPL was high compared to DCM and RCL (P<0.05). RCL exhibited a significant (P<0.05) potent antioxidant activity in nitric oxide radical inhibition. Inhibition diameter zone (nearest mm) of extracts against the test bacteria ranged from 11.5 in RCL to 12.5 in DCM against Staphylococcus aureus, from 10.5 in RCL to 13.5 in DCM against Streptococcus pneumoniae, from 8.5 in DCM to 10.5 in RCL against Escherichia coli, and the same inhibition of 10 mm in three of the extracts against Klebsiella pneumoniae. However, there was no inhibition against fungi Aspergillus niger and Candida albicans. Three of the extracts had the same minimum inhibitory concentration values of 12.50, 12.50, and $6.25{\mu}g/mL$ against S. aureus, K. pneumoniae, and S. pneumoniae, respectively. On the other hand, MIC values of 12.50, 12.50, and $6.50{\mu}g/mL$ were recorded for RPL, DCM, and RCL against E. coli, respectively. The result of present study revealed that extracts from three kinds of strawberries could be potential candidates as antioxidant and antimicrobial sources for functional food industries.

도깨비부채 잎 추출물의 NF-κB 활성화를 통한 대장암 세포 HCT116에 대한 세포생육 억제활성 (Inhibitory Effect of the Rodgersia podophylla Leave Extracts against Cell Proliferation through Activation of NF-κB in Human Colorectal Cancer Cells)

  • 김정동;정진부
    • 한국자원식물학회지
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    • 제33권5호
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    • pp.460-466
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    • 2020
  • 본 연구 결과들을 바탕으로 도깨비부채 잎(RPL)은 GSK3β활성화를 통해 IκB-α를 인산화시켜 단백질 분해를 유도하고 IκB-α분해로 인해 p65 핵내 전이를 유도하여 NF-κB 신호전달을 활성화시킨다. 이러한 NF-κB 신호전달 활성화를 통해 대장암의 세포생육을 억제하는 것으로 추정된다. 본 결과는 도깨비부채 잎을 소재로 항암을 목적으로 한 천연치료제 및 대체보완소재 개발에 활용할 수 있다고 판단된다. 그러나 도깨비부채 잎의 대장암에 대한 세포생육 억제와 작용기전의 정확한 관련성과 세포생육 억제활성 물질 분석을 위해 추가적인 연구가 필요할 것으로 사료된다.

한국산 피나무속(Tilia L.) 식물의 분자 계통학적 연구 (Molecular Phylogenetic Study of Korean Tilia L.)

  • 부다운;박선주
    • 한국자원식물학회지
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    • 제29권5호
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    • pp.547-554
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    • 2016
  • 피나무속 식물은 화경의 아래에 부착된 선형의 포를 특징적으로 가지고 있으며 이러한 형질은 아욱과의 다른 속과 구분된다. 본 연구는 피나무속의 종간 계통학적 유연관계를 규명하고자 하였다. 계통학적 분석은 한국과 일본의 피나무속 10종, outgroup으로 멕시코목화를 선정하여 수행하였다. nrDNA의 ITS와 cpDNA의 trnL-F, rpl32-trnL의 염기서열을 확보하여 분석하였다. ITS, trnL-F 와 rpl32-trnL의 data를 유합한 결과 계통수는 6개의 분계조로 구성되었다. 구주피나무는 outgroup과 가장 가깝게 나타났다. 피나무 , 뽕잎피나무 그리고 털피나무는 한 분계조를 형성하였다. 연밥피나무, 섬피나무, 일본피나무는 각각 독립적인 분계조를 형성하였다. 섬피나무는 일본피나무와 가장 가까운 관계를 보여주었다. 보리자나무, 찰피나무, 염주나무는 하나의 분계조를 형성하여 서로 근연관계에 있음을 보여주었다.

RPL에서 DIS 메시지를 이용한 Storing 노드 추가 및 Instance 평준화 기법 연구 (A Study on Storing Node Addition and Instance Leveling Using DIS Message in RPL)

  • 배성현;윤정오
    • 전기전자학회논문지
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    • 제22권3호
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    • pp.590-598
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    • 2018
  • 최근 사물들에 인터넷 서비스를 제공하는 IoT(Internet of Things) 기술에 관한 관심이 높아지고 있다. IoT는 홈 네트워크, 헬스 케어, 재난 알림 등에서 다양한 서비스를 제공하고 있다. LLN(Low Power & Lossy Networks) 특징을 갖는 IoT는 빈번한 센서 노드의 손실이 발생한다. IoT의 표준 라우팅 프로토콜인 RPL은 센서 노드의 손실이 발생하면 전체 경로 재설정(Global repair)을 수행하여 데이터를 전송한다. 하지만 낮은 사양의 센서 노드로 인한 빈번한 센서 노드 손실은 잦은 전체 경로 재설정으로 인해 네트워크 성능 저하를 일으킨다. 본 논문에선 Storing mode 센서 노드 선정 이후에도 잦은 경로 재설정 문제로 인한 네트워크 성능 저하 문제를 해결하기 위한 Storing mode 센서 노드의 추가 선정 방법을 제안하고 각 Instance의 전체 경로 재설정 횟수의 평준화 방법을 제안하고자 한다.

Administration of encapsulated L-tryptophan improves duodenal starch digestion and increases gastrointestinal hormones secretions in beef cattle

  • Lee, Sang-Bum;Lee, Kyung-Won;Wang, Tao;Lee, Jae-Sung;Jung, U-Suk;Nejad, Jalil Ghassemi;Oh, Young-Kyoon;Baek, Youl-Chang;Kim, Kyoung Hoon;Lee, Hong-Gu
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권1호
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    • pp.91-99
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    • 2020
  • Objective: This study investigated the effects of oral administration of rumen-protected L-tryptophan (RPL-T) on duodenal starch digestion and gastrointestinal hormones (GIH) secretions using Hanwoo beef steers as the animal models. Methods: Four steers (423±24 kg) fitted with ruminal and duodenal cannulas were employed in a crossover design replicated twice. Treatments were control (basal diet) and RPL-T (basal diet+191.1 mg/kg body weight [BW]) group. Blood and duodenal samples were collected to measure serum GIH levels and pancreatic α-amylase activity at day 0, 1, 3, and 5 (-30, 30, 90, 150, and 210 min) of the study. Samples from each segment of the gastrointestinal tract were collected via ruminal and duodenal cannulas and were used to determine soluble protein and the starch digestion rate at days 6 (-30, 180, 360, and 540 min) and 8 (-30, 90, 270, and 450 min) of the experiment. Results: No significant difference in ruminal pH, NH3-N, and total volatile fatty acid including the levels of acetate, propionate, butyrate, isobutyrate, valerate, isovalerate, and the acetate-to-propionate ratio was observed between groups (p>0.05). Crude protein uptake was higher and feces starch content was lower in RPL-T group than the control group (p<0.05). The D-glucose contents of feces in RPL-T group decreased at day 5 compared to those in the control group (p<0.05), however, no change was found at day 0, 1, or 3 compared to the control group (p>0.05). Serum cholecystokinin (CCK), melatonin, duodenal pancreatic α-amylase activity, and starch digestion were significantly higher in RPL-T group than the control group (p<0.05). Conclusion: Taken together, oral administration of RPL-T at the rate of 191.1 mg/kg BW consistently increased CCK concentration, pancreatic α-amylase activity in duodenal fluids, and starch digestion rate in the small intestine and thus found to be beneficial.

Comparative Study of the Effective Dose from Panoramic Radiography in Dentistry Measured Using a Radiophotoluminescent Glass Dosimeter and an Optically Stimulated Luminescence Detector

  • Lee, Kyeong Hee;Kim, Myeong Seong;Kweon, Dae Cheol;Choi, Jiwon
    • Journal of the Korean Physical Society
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    • 제73권9호
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    • pp.1377-1384
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    • 2018
  • Accurate measurement of the absorbed dose and the effective dose is required in dental panoramic radiography involving relatively low energy with a rotational X-ray tube system using long exposures. To determine the effectiveness of measuring the irradiation by using passive dosimetry, we compared the entrance skin doses by using a radiophotoluminescent glass dosimeter (RPL) and an optically stimulated luminescence detector (OSL) in a phantom model consisting of nine and 31 transverse sections. The parameters of the panoramic device were set to 80 kV, 4 mA, and 12 s in the standard program mode. The X-ray spectrum was applied in the same manner as the panoramic dose by using the SpekCalc Software. The results indicated a mass attenuation coefficient of $0.008226cm^2/g$, and an effective energy of 34 keV. The equivalent dose between the RPL and the OSL was calculated based on a product of the absorbed doses. The density of the aluminum attenuators was $2.699g/cm^3$. During the panoramic examination, tissue absorption doses with regard to the RPL were a surface dose of $75.33{\mu}Gy$ and a depth dose of $71.77{\mu}Gy$, those with regard to the OSL were surface dose of $9.2{\mu}Gy$ a depth dose of $70.39{\mu}Gy$ and a mean dose of $74.79{\mu}Gy$. The effective dose based on the International Commission on Radiological Protection Publication 103 tissue weighting factor for the RPL were $0.742{\mu}Sv$, $8.9{\mu}Sv$, $2.96{\mu}Sv$ and those for the OSL were $0.754{\mu}Sv$, $9.05{\mu}Sv$, and $3.018{\mu}Sv$ in the parotid and sublingual glands, orbit, and thyroid gland, respectively. The RPL was more effective than the OSL for measuring the absorbed radiation dose in low-energy systems with a rotational X-ray tube.