• The Korea Journal of Herbology
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• v.20 no.4
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• pp.151-161
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• 2005

Objectives : Our research purpose is to establish the standard identification analysis on C. officinale and L. chuanxiong in Korea and China by PCR-mediated fingerprinting. Methods : The Restriction Fragment Length Polymorphism (RFLP) and Randomly Amplified Polymorphic DNA (RAPD) method was used on Internal Transcribed Spacer (ITS) regions and rbcL regions to compare and discriminate genes extracted from crude drugs as C. officinale and L. chuanxiong in Korea and China. Results : L. chuanxiong Korea and China have very similar polymorphism, whereas L. chuanxiong in Korea and C. officinale have very different polymorphism in RFLP. And restriction enzymes AluI and SacI forms the specific fragment band only in C. officinale, they can be used as RFLP marker on ITS regions to discriminate among the species. Conclusions : The results could be applied in discriminating crude drugs among C. officinale and L. chuanxiong in Korea and China. Also they could be used in controlling drug quality, preserving medicinal plants, and improving plant description.

• IEMEK Journal of Embedded Systems and Applications
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• v.12 no.3
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• pp.149-157
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• 2017

In this paper, we propose BCMR (Block Classification with Monitor and Restriction) to ensure the isolation and to reduce the interference of blocks between a garbage collection and a wear leveling. The proposed BCMR monitors an endurance variation of blocks during the garbage collection and detects hot blocks by making a restriction condition based on this information. The proposal induces a block classification by its update frequency for the garbage collection and the wear leveling, so we will get a prolonged lifetime of NAND flash memory systems. In a performance evaluation, BCMR prolonged the lifetime of NAND flash memory systems by 3.95%, on average and reduced a standard deviation per block by 7.4%, on average.

• Journal of the Korean Institute of Rural Architecture
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• v.3 no.3
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• pp.47-55
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• 2001

For several years by discussion and research, the designing plan and detail plans of year 2000 has been unified. By this result the District Standard Planning as well as the following existing town to control all sorts of living surrounding problems and to make a delightful arranged town are the purpose, which is carrying out all over the country. It is true that the expectation was high to the District Standard Planning. Because of this plan it could use and control the District special quality. Such as, it could rise the ability of beautiful sight and make a advisable town. But in this study the first preceding subject is a problem by the constructing work that the restriction and the standard application has been strong. So the District Standard Planning had many problems. And also by the problems here, as a immoderate volition and stiffen about the operation, the system and equipment lack about the environment improving work, problems with areas by the exciting plannings, the attitude of the executive agency that can't accept the inhabitants will. From these backgrounds we thought the research has not to be standardize in only newtown concept, but has to breath with the exciting towns and the rural areas that the District Planning has been applied. And to revive the special quality of the area and local government by a positive and logical research. Consequently in this study, we researched about the problems of architectures that had issues with the District Standard Planning of architectural part of operation guide which has been assisted form Single-Detached House in Eomsa District Dooma-Myun Nonsan which is located in Chungnam province.

• Journal of The Korean Digital Architecture Interior Association
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• v.9 no.3
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• pp.25-35
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• 2009

This study is planning improvement of welfare facilities about the hall for the aged in apartment housing. An apartment house, famous residential type in Korea, put an important value on its convenience and economical efficiency of furniture arrangement by maximizing floor space index. In this regard, leisure usage of house was not carefully considered for the aged people. To redefine the efficiency of welfare facilities, research mainly deals with analysis of realistic needs for the aged through the spot survey and interview. The main purpose of this study is to enhance the quality of welfare facilities and propose the improved welfare facilities for the aged people. Through the research, conclusions are as followed First, Facility standard and provisions of the law should be revised for considering population growth of the aged people. Second, there are 4 plan types in the hall for the aged. Contrary to our expectation, diversity of program was not found however various program planning is needed for considering its different types of plan. Third, according to regulation, space restriction is based on the number of households. Therefore, room and space standard does not depend on the number of people. From now on, in order to improve quality of welfare facilities of the aged, revision of laws and overall facility standard should be implemented in advance.

• The Korean Society of Law and Medicine
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• v.19 no.2
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• pp.75-98
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• 2018

Recently, the antitrust tribunal of Seoul High Court revoked the disposition of Korea Fair Trade Commission(hereafter 'KFTC'). While KFTC determined that the restriction of Korea Pediatrician Association violated article 26 of the Monopoly Regulation and Fair Trade Act(Korean antitrust law), Seoul High court viewed that KFTC failed to prove the compulsory measures and the restraint of competition required in article 26. The 'restriction' of article 26 should be interpreted as 'excessive restriction'. Since entrepeneurs' organization is allowed to limit its member's activities, KFTC could regulate entrepeneurs' organization on a very exceptional basis. In addition, though entrepeneurs' organization did not use compulsory measures to enforce its resolution, its 'excessive restriction' could fit into the notion of 'restriction' of article 26. Under the current medical care system, the price of medical care is decided by Korean government. Therefore the restriction of Korea Pediatrician Association is not likely to have effect on the price. However, the resolution of Korea Pediatrician Association was aimed to decrease the supply of medical care. Therefore the resolution is capable of having effect on the competition. In this sense, though KFTC failed to submit direct evidence to support the decrease of quantity, there could be possibility of restraint of competition. The Seoul High Court's decision has important implications. The leading case on restraint of competition(Supreme Court 2002Du8628, Posco case) was delivered in 2007. However the remaining issue such as the standard and scope of restraint of competition is not clear. Through reappeal case of this decision, Supreme Court has to decide the line between competition and its restraint.

• Journal of Korean Physical Therapy Science
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• v.10 no.2
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• pp.62-72
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• 2003

The purpose of this study is to prove the efficacy of the Kaltenborn-Evjenth Orthopedic Manipulative Therapy and the Conventional Physical Therapy that influence changes in pain and range of motion when those therapies are applied to patients with temporomandibular pint movement restriction. The subjects of the study were 30 randomly selected patients who had been diagnosed with temporomandibular pint movement restriction and had endured pain for more than two weeks. These patients had visited one of three hospitals in Pyongchon 00 Hospital. The subjects were divided into two groups with 15 patients each. The Kaltenborn-Evjenth Orthopedic Manipulative Therapy was applied to one group and the Conventional Physical Therapy was applied to the other group, once a day for three days. Then, the pain perception degree was measured by using the Visual Analogue Scale(VAS) and a digital device(Absolute Digimatic) measured the range of motion for each group. The average and standard errors were calculated for each measured items and a paired t-test was used for identifying significance in the differences in the pain perception degree and the range of motion between the two groups according to therapy. The significant level was set as ${\alpha}=0.05$. The changes in the pain perception degree were statistically significant in both groups; however, the group that received Kaltenborn-Evjenth Orthopedic Manipulative Therapy(KE-Group) showed more significant changes in a decrease in the pain perception degree than did the group that received the Conventional Physical Therapy(CPT-Group). Both groups showed significant results regarding changes in the range of motion: however, the KE-Group showed more of a significant difference in the average of the range of motion than did the CPT-Group(p<0.001). Comparing the changes in the range of motion between the two groups, the KE-Group showed a significant result which means that the KE-Group had a higher therapy effect than did the CPT-Group(p<0.05). Based on the results of this study, we found that the Kaltenborn-Evjenth Orthopedic Manipulative Therapy decreased pain and increased the range of motion. With such findings, we expect that the Kartenborn-Evjenth Orthopedic Manipulative Therapy can be used as an effective treatment method for patients with tempomrnandibular pint movement restriction and that the treatment period can be reduced with this therapy as well.

• Journal of Preventive Medicine and Public Health
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• v.19 no.2 s.20
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• pp.203-212
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• 1986

Hypertension is one of the most well known risk factors for cerebrovascular or coronary heart disease and is a major public health problem. Early detection and treatment of hypertension are essential, but the compliance of treatment on hypertension is not easy to achive. Hypertensive workers are being detected by the annual screening under the Labour Standard Law in Korea but the solidified control system for them is not existing. This study about workers 'Motive-Belief-Action in non-drug and drug treatment of their hypertension would be worthwhile to interpret how the workers actually behave in coping with hypertension, and also would be advisable to construct the follow-up program in Korea. In the field research process two criteria were used to select sample group. The first criterion included the workers who were screened to be hypertensive with their blood pressure above 160/95 in this survey. The second one was used to classify study-group respondents who had known their hypertension by successive annual screening. From such criteria a total of 156 male workers were sampled in 21 industries, the author interviewed them using the structured questionnaire which consisted of Belief-Motive-Action items about non-drug and drug treatment for hypertension with open-ended question on symptom of hypertension. The summary is as follows: 1) Sixty-one percent of respondents had ever checked their blood pressure somewhere besides the annual screening. 2) Most respondents(97.2%) complained no symptoms of hypertension at all. 3) Belief level of non-drug treatment was relatively high (82.1%-64.7%), but motive(55.1%-28.2%) and action(38.5%-16.7%) levels were low. 4) Belief level of drug treatment was relatively lower than that of non-drug treatment, blue collar workers showed higher artier level of drug treatment than white collar workers, and correlation coefficient between belief and motive on drug treatment was lower in group of not-recognizing their family history of hypertension than recognized group. Such findings indicated that belief on drug treatment of hypertensive workers would be problematic. 5) White collar workers showed significant lower correlation coefficients between Motive and Action of salt restriction, restriction of fatty diet and relaxation than blue collar workers. 6) Mild hypertension group showed low levels of Motive and Action of non-drug treatment(salt restriction, restriction of fatty diet and relaxation) and also showed low correlation coefficient between Belief and Motive of above non-drug treatment.

• BMB Reports
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• v.39 no.4
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• pp.464-467
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• 2006

Recently, the nucleotide sequences of entire genomes became available. This information combined with older sequencing data discloses the exact chromosomal location of millions of nucleotide markers stored in the databases at NCBI, EMBO or DDBJ. Despite having resolved the intron/exon structures of all described genes within these genomes with a stroke of a pen, the sequencing data opens up other interesting possibilities. For example, the genomic mapping of the end sequences of the human, murine and rat BAC libraries generated at The Institute for Genomic Research (TIGR), reveals now the entire encompassed sequence of the inserts for more than a million of these clones. Since these clones are individually stored, they are now an invaluable source for experiments which depend on genomic DNA. Isolation of smaller fragments from such clones with standard methods is a time consuming process. We describe here a reliable one-step cloning technique to obtain a DNA fragment with a defined size and sequence from larger genomic clones in less than 48 hours using a standard vector with a multiple cloning site, and common restriction enzymes and equipment. The only prerequisites are the sequences of ends of the insert and of the underlying genome.

• Journal of Korean Society for Quality Management
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• v.47 no.3
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• pp.523-535
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• 2019

Purpose: We research on the efficient response surface methodology(RSM) design to develop a design space in Quality by Design(QbD). We propose practical designs for the successful construction of the design space in QbD by allowing different number of replicates at the box points, star points, and the center point in the rotatable central composite design(CCD). Methods: The fraction of design space(FDS) plot is used to compare designs efficiency. The FDS plot shows the fraction of the design space over which the relative standard error of predicted mean response lies below a given value. We search for practical designs whose minimal half-width of the tolerance interval per a standard deviation is less than 4.5 at 0.8 fraction of the design space. Results: The practical designs for the number of factors between two and five are listed. One of the designs in the list could be chosen depending on the experimental budget restriction. Conclusion: The designs with box points replications are more efficient than those with the star points replication. The sequential method to establish a design space is illustrated with the simulated data based on the two examples in RSM.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2012.11a
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• pp.197-198
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• 2012

If the mechanical development be applied to the Nuclear Power Plant Structures instead of the standard hook development, the problem of overcrowding re-bars in the anchorage zone can be solved and the construction quality of the concrete work will be improved. But there are some problems in applying it to the NPP structures because of the restriction on the re-bar yield strength and diameter. After the performance evaluation test for the mechanical development, we can develop the new design equation of the mechanical development length in order to solve the limitation and apply it to NPP structures.