• Journal of the East Asian Society of Dietary Life
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• v.17 no.1
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• pp.43-50
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• 2007

This study investigated the effects of mycelia of Lentinus edodes mushroom-cultured Glycyrrihiza radix(LMG) on cancer cell lines and sarcoma 180(S-180), as well as on human mast cells. In an anti-cancer tests using Hep3B(hepatic cancer cell), MCF-7(breast cancer), and HeLa(uterine cancer) cells, LMG extract exhibited greater anti-proliferation effects than Glycyrrihiza glabra(GG) extract. LMG extract multiplication restraining effects were 60% that of ethanol at 3 mg/mL extract also displayed tumor suppressive effects in mice injected with S-180 cells. The growth-inhibition rates against tumor cells were 56% for LMG and 37% for GG. When LMG was added to human mast cells, the Intensity of RT-PCR products using primers($FC{\varepsilon}RI\;c-kit$) decreased. significantly compared with that of control. These results suggest that Lentinus edodes Mushroom-Cultured Glycyrrhiza glabra has an anti-proliferation effects against cancer cell lines(Hep3B, MCF-7 and HeLa) and S-180 tumors and will be also beneficial in treating allergic reactions.

• Computers and Concrete
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• v.31 no.2
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• pp.123-137
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• 2023

To fully understand shear mechanisms and composite effects of circular concrete-filled steel tube (CFST) columns, systematic numerical investigations were conducted in this paper by improved finite element models. The triaxial plastic-damage constitutive model of the concrete and the interactions between the concrete and steel tube were considered. Afterwards, the critical and upper bound shear span ratios of the circular CFST column under lateral shear loading were determined. The composite effects between the two materials were analyzed by comparing the shear resistance with plain concrete column and hollow steel tube. In addition, a method that predicts the shear bearing capacity of a circular CFST column was proposed. The confining effects on the concrete core and the restraining effects on the steel tube were considered in this method. The proposed formula can predict more accurate results than the methods in different codes and references.

• Journal of Veterinary Clinics
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• v.40 no.6
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• pp.429-437
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• 2023

In veterinary medicine, most radiographic images are obtained by restraining patients, inevitably exposing the restrainer to secondary scattered radiation. Radiation exposure can result in stochastic reactions such as cancer and genetic effects, as well as deterministic reactions such as skin burns, cataracts, and bone marrow suppression. Radiation-shielding equipment, including aprons, thyroid shields, eyewear, and gloves, can reduce radiation exposure. However, the risk of radiation exposure to the upper arms, face, and back remains, and lead aprons and thyroid shields are heavy, restricting movement. We designed a new radiation-shielding system and compared its shielding ability with those of conventional radiation-shielding systems. We hypothesized that the new shielding system would have a wider radiation-shielding range and similar shielding ability. The radiation exposure dose differed significantly between the conventional and new shielding systems in the forehead, chin, and bilateral upper arm areas (p < 0.001). When both systems were used together, the radiation-shielding ability was better than when only one system was used at all anatomical locations (p < 0.01). This study suggests that the new radiation-shielding system is essential and convenient for veterinary radiation workers because it is a step closer to radiation safety in veterinary radiography.

• Transactions of Materials Processing
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• v.17 no.7
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• pp.511-516
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• 2008

A drawbead die for the experimental determination of drawbead forces was newly introduced in this paper. While the conventional Nine's drawbead die inevitably includes effects of a blank holding force on the measured drawbead forces, the new drawbead die excludes it by removing the blank holder contact in the dieface. Therefore, the new drawbead die can provide more realistic drawbead forces without considering somewhat arbitrary effect of blank holder with the computational procedure of forming process. The drawbead opening force and restraining force obtained by adopting the two experimental dies were compared for the validation of accuracy in the FEM simulation of automotive fender forming process. The compared section strains and draw-ins confirmed that the present drawbead die provides better drawbead forces for an accurate FEM simulation of sheet metal forming process.

• Proceedings of the Korea Concrete Institute Conference
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• 2006.05a
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• pp.514-517
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• 2006

Nonseismic designed RC frame have a possibility of shear failure because of deficiencies of reinforcing details. To model the shear failure in numerical analysis, shear strength degradation models which include Moehle's and ATC 40 are compared and applied to push-over analysis. For numerical analysis, three storied building frame is selected and designed according to Korean Concrete Design Code(2003). From the numerical analysis, it is pointed out that there may be great difference in lateral drift capacity if a different shear strength model is used. And the capacity can be severely underestimated if the restraining model of plastic rotation of ATC 40 is used, compared to the use of shear spring for shear degradation.

• Steel and Composite Structures
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• v.4 no.3
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• pp.211-226
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• 2004

This paper presents a study on the structural behaviour of modular steel scaffolds through both experimental and numerical investigations. Three one-storey and three two-storey modular steel scaffolds were built and tested to failure in order to examine the structural behaviour of typical modular steel scaffolds. Details of the tests and their test results were presented in this paper. Moreover, an advanced non-linear analysis method was employed to evaluate the load carrying capacities of these scaffolds under different support conditions. Comparisons between the experimental and the numerical results on the structural behaviour of these modular steel scaffolds were also presented. Moreover, the restraining effects of external supports in practical situations were also studied through finite element methods. The predicted load carrying capacities and deformations at failure of these models under partially restrained conditions were found to be close to the experimental results. A codified design method for column buckling with modified slenderness ratios was adopted for practical design of modular steel scaffolds.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.4 no.1
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• pp.43-58
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• 1991

In order to verify the effect of Sineungyangjin-Dan on alopecia, I experimented the hair regrowth of the normal mice and of the high butter diet-pretreated mice by feeding each group of mice a certain amount of ethanol extract of Sineungyangjin-Dan and water extract and thus obtained the results as follow; 1. The ethanol extract of Sineungyangjin-Dan was proved to promote the hair regrowth of the hair-removed normal mice. 2. 360mg/kg ethanol extract of Sineungyangjin-Dan was proved to have the effect of promoting hair regrowth by restraining the increase of free cholesterol and triglyceride but by helping the increase of free fatty acid in skin. As a result of the above study Sineungyangjin-Dan was proved to have the effect of promoting hair regrowth.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2007.04a
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• pp.223-226
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• 2007

In current specification, modification factor(B) for web-tapered beam is used to account for the stress gradient and the restraining effect for adjacent spans. However, because these effects are considered together in modification factor, this paper revaluate the accuracy of the modification factor used in current specification. Also this paper investigate the flexural torsional buckling strength of laterally fixed thin-walled arch with doubly symmetric section using the analytical and numerical method. From this investigate the concept of effective length to consider the out-of-plane boundary condition for straight column or beam is not applicate for the flexural-torsional buckling of laterally fixed arches.

• Transactions of Materials Processing
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• v.5 no.2
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• pp.130-137
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• 1996

The sheet formability can be improved by the optimum drawbeads installation because draw-beads can control the flow of the metal into the die cavity when the punch enters into the die opening, In this study the drawing characteristics for step drawbead are analyzed by 2-D rigid -plastic FEM and also are measured experimentally. In addition for the validity of FEM theoretical results are compared with the experimental results. Especially the draw bead restrain-ing forces and the strain distributions of drawn specimens are obtained in both FEM and experiment. Also the effects of the drawbead dimensions drawing angles and blank holding forces on the drawing characteristics are investigated.

• Journal of the East Asian Society of Dietary Life
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• v.23 no.1
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• pp.44-52
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• 2013

This study investigated hepatic functional improvement and anti-fibrotic effects of water extracts of black tea. Male Sprague-Dawley rats were divided into four groups (normal, control, and two experimental subgroups: Ba, Bb) and observed for 3 weeks. Liver fibrosis in rats developed from carbon tetrachloride ($CCl_4$) administration, except for the normal group. Except for the normal and control group, the two experimental subgroups were fed water extracts of black tea. The food efficiency ratio significantly increased in the experimental group compared to the control group. The experimental group had a significantly lower liver weight compared to the control group. The ratio of liver weight to body weight was significantly lower in the experimental group than the control group. The levels of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, blood urea nitrogen, and low-density lipoprotein-cholesterol in serum significantly decreased in the experimental group compared to the control group. The values of hydroxyproline and malondialdehyde in liver were even lower in the experimental group than the control group. In observations on liver histology, weaker inflammation and fibrosis were observed in the experimental group compared to the control group. In conclusion, water extracts of black tea help hepatic cells keep their functions, restraining and protecting the liver from impairments caused by $CCl_4$ administration, and can be effective as anti-fibrotic agents.