• Proceedings of the KWS Conference
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• 2006.05a
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• pp.304-306
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• 2006

Positioning the workpiece accurately and preventing the weld distortion, tack welding is often performed before main welding in the construction of welded structures. The weld bead size of the tack weld is determined according to the workpiece thickness, weld length, weld joint type etc. However, this tack weld deteriorates the final weld bead profile, so that the grinding process is usually adopted for the uniform weld bead profile. In this study, an experimental method for the selection of optimal welding condition was proposed in the fillet weld which was done over the tack weld. This method uses the response surface analysis in which the leg length and the reinforcement height of weld bead were chosen as the quality variables of weld bead profile. The overall desirability function, which was combined desirability function for the two quality variables, was used as the objective function for getting the optimal welding condition. From the result, it was revealed that a uniform weld bead can be obtained by adopting the optimal welding condition which was determined according to the method proposed.

• Toxicological Research
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• v.22 no.4
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• pp.323-328
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• 2006

Global gene expression profile was analyzed by microarray analysis of rat liver RNA after acute acetaminophen (APAP) administration. A single dose of 1g/kg body weight of APAP was given orally, and the liver samples were obtained after 24, 48 h, and 2 weeks. Histopathologic and biochemical studies enabled the classification of the APAP effect into injury (24 and 48 h) and regeneration (2 weeks) stages. The expression levels of 4900 clones on a custom rat gene microarray were analyzed and 484 clones were differentially expressed with more than a 1.625-fold difference(which equals 0.7 in log2 scale) at one or more time points. Two hundred ninety seven clones were classified as injury-specific clones, while 149 clones as regeneration-specific ones. Characteristic gene expression profiles could be associated with APAP-induced gene expression changes in lipid metabolism, stress response, and protein metabolism. We established a global gene expression profile utilizing microarray analysis in rat liver upon acute APAP administration with a full chronological profile that not only covers injury stage but also later point of regeneration stage.

• Steel and Composite Structures
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• v.32 no.1
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• pp.111-126
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• 2019

This paper deals with experimental investigation and modeling of the static behavior of a novel RCS beam-column exterior joint. The studied joint detail is a through-column type in which an H steel profile totally embedded inside RC column is directly welded to the steel beam. The H steel profile was covered by two supplementary plates in the joint area in order to avoid the stirrups resisting shear in the joint area. Two full-scale through-column-type RCS joints were tested under static loading. The objectives of the tests were to examine the connection performance and to highlight the contribution of two supplementary plates on the shear resistance of the joint. A reliable nonlinear 3D finite element model was developed using ABAQUS software to predict the response and behavior of the studied RCS joint. An extensive parametric study was performed to investigate the influences of the stirrups, the encased profile length and supplementary plate length on the behavior of the studied RCS joint.

• Journal of the Korean Society of Propulsion Engineers
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• v.2 no.2
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• pp.88-98
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• 1998

A waveform for shock response spectrum test on a shaker is synthesized using wavelets such that a specified shock response spectrum of a test profile is achieved. The parameters of a wavelet are center frequency, amplitude, number of half cycles, delay and polarity. The amplitude of each wavelet component is iteratively adjusted so a specified shock response spectrum is matched. The waveform so synthesized is regarded as a reference acceleration waveform for a shaker shock response spectrum test. The author proposes the use of a long duration and low peak waveform. The usefulness of this approach is illustrated with some examples.

• Molecules and Cells
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• v.19 no.2
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• pp.167-179
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• 2005

The cells of metazoans respond to DNA damage by either arresting their cell cycle in order to repair the DNA, or by undergoing apoptosis. This response is highly conserved across species, and many of the genes involved in this DNA damage response have been shown to be inactivated in human cancers. This suggests the importance of DNA damage response with regard to the prevention of cancer. The DNA damage checkpoint responses vary greatly depending on the developmental context, cell type, gene expression profile, and the degree and nature of the DNA lesions. More valuable information can be obtained from studies utilizing whole organisms in which the molecular basis of development has been well established, such as Drosophila. Since the discovery of the Drosophila p53 orthologue, various aspects of DNA damage responses have been studied in Drosophila. In this review, I will summarize the current knowledge on the DNA damage checkpoint response in Drosophila. With the ease of genetic, cellular, and cytological approaches, Drosophila will become an increasingly valuable model organism for the study of mechanisms inherent to cancer formation associated with defects in the DNA damage pathway.

• Tribology and Lubricants
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• v.14 no.4
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• pp.121-127
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• 1998

In this study, a numerical procedure to solve a contact problem has been developed. The procedure takes advantage of signal processing technique in frequency domain to achieve shorter computing time. Boussinesq's equation was adopted as the response function. This procedure is applicable to a non-periodic surface profile as well as a periodic one. The validity of this procedure has been established by comparing the numerical results with the exact solutions. The fastness of this procedure was shown in comparison with other algorithm.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.94.2-94
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• 2002

$\textbullet$ The method to have real-time response at the motion control. $\textbullet$ The trajectory generation method guarantees the continuous acceleration in changing the velocity during the actuator is moving. $\textbullet$ We propose the velocity profile generation algorithm in order to change object position or object velocity with continuous acceleration using blending method.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.121-121
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• 2000

This paper presents a design of macro-micro system for high-speed mounting of micro-chips. A macro motion device is driven by DC servomotor and ball screw mechanism. To obtain fast response, a micro motion device utilizes a precision elector magnetic actuator In order to reduce peak impact force, We evaluate the design parameters that have an effect on it. And a characteristic of response is simulated using PID controller in velocity and force control.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.24 no.6
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• pp.437-443
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• 2014

Vibration testing is conducted for evaluate the fatigue resistance of responsible system over excitation situations and two kinds of vibration profiles, harmonic or random, are widely used in engineering fields. Harmonic excitation profile is adequate for the rotating machinery that is primarily exposed to the orderly excited force subjected for a rotating speed; Random profile is suitable for the non-stationary vibration input, that is a ground excitation for example. Recently, the sine on random(SOR) testing method was sometimes considered to represent the real excitation conditions since the measured response signals of a target system, expecially for moving mobility, shows usually a mixture of them. So, it is important to understand the accumulated fatigue damage over different excitation patterns, harmonic and/or random, to determine the efficient vibration profile of a target system. A uniaxial vibration testing with a notched simple beam was introduced to evaluate the fatigue damage for different excitation profiles and the best choice of vibration profile was concluded from those comparison of calculated fatigue damages.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2014.04a
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• pp.340-345
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• 2014

Vibration testing is conducted for evaluate the fatigue resistance of responsible system over excitation situations and two kinds of vibration profiles, harmonic or random, are widely used in engineering fields. Harmonic excitation profile is adequate for the rotating machinery that is primarily exposed to the orderly excited force subjected for a rotating speed; Random profile is suitable for the non-stationary vibration input, that is a ground excitation for example. Recently, the sine on random (SOR) testing method was sometimes considered to represent the real excitation conditions since the measured response signals of a target system, expecially for moving mobility, shows usually a mixture of them. So, it is important to understand the accumulated fatigue damage over different excitation patterns, harmonic and/or random, to determine the efficient vibration profile of a target system. A uniaxial vibration testing with a notched simple beam was introduced to evaluate the fatigue damage for different excitation profiles and the best choice of vibration profile was concluded from those comparison of calculated fatigue damages.