• Journal of Korean Clinical Nursing Research
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• v.23 no.1
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• pp.20-29
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• 2017

Purpose: The purpose of this study was to investigate symptoms experienced by patients who reported fever at the emergency room (ER) and to identify any existing cluster of symptom related to fever. Methods: The study used a retrospective and descriptive design with secondary data analysis. Data were abstracted from 665 medical records of patients with fever who visited ER from September 1, 2015 to August 31, 2016 at a tertiary hospital. Results: The most frequently reported symptoms included cold (43.9%), myalgia (24.1%), headache (16.2%), general weakness (15.3%), respiratory symptoms (12.3%), gastrointestinal (GI) symptoms (12.0%), mental change (4.5%), sweating(1.8%), and warmth (0.9%). Analysis of the symptoms related to fever revealed seven symptom clusters; Cluster 1 (n=190) included cold (100%) and myalgia (28.9%); Cluster 2 (n=37), headache (100%) and myalgia (32.4%); Cluster 3 (n=33), GI symptoms (100%), general weakness, headache, and cold; Cluster 4 (n=34), cold (100%), myalgia, headache, and respiratory symptoms; Cluster 5 (n=241), respiratory symptoms (10.8%); Cluster 6 (n=76): myalgia (75.0%) and general weakness, and Cluster 7 (n=54), cold (87.0%), general weakness, and respiratory symptoms. Conclusion: The results of this comprehensive symptom assessment are hoped to be helpful in developing better symptom management for ER patients with fever than before. Further research is warranted to verify the symptom clusters of this study in different clinical settings.

• Journal of Environmental Health Sciences
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• v.17 no.2
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• pp.67-77
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• 1991

The purpose of this study was to investigate the psychosomatic health status of printers. The 77 printers and 24 control group were analysed about salary, drinking, smoking, education, sex, marriage, age and working age by the THI (Todai Health Index) questionaire. THI was modified from CMI(Cornell Medical Index) and developed by Tokyo University Research Team in Japan. The resuts obtained were summarized as follows. 1. The printers, who get more salary showed high score about mental conplaints, especially, mental irritability(j), nervusness (E), lie Scale(L), aggressiveness(F) and irregualr life(G) and lower salary showed generally high score about physical complaints, especially, mouth and anus (D), digestive symptom(C) multiple subjective symptom(I). 2. According to the printers drinking amount shows the difference, eg nondrinker scored higher on mouth and anus(D), 90mg/week drinker scored higher on multiple subjective symptom(I), digestive symptom(C), depression(K), nervousness(E), and irregular life(G), 91~179mg/week drinker scored higher on impulsiveness(H), mental irritability(J), 270~359mg/week drinker scored higher on respiratory(A), lie scale (L) and aggressiveness (F). 3. The nonsmoker scored high level on mouth and anus(D), mental irritability(J). The previous smoker scored on multiple symptom(I), eyes and skin(B), digestive(C), lie scale(L), and depression(K). The present smoker scored on respiratory(A), impulsivehess(H), aggressiveness(F), nervousness(E), and irregular life(G). 4. According to the printers working age showed almost high score about subjective symptoms on 1~3 year. 5. Men printers high scored on respiratory(A). lie scale(L), aggressiveness(F), women printers scored about mental complaints, especially, impulsiveness(H), mental irritability(J), depression (K), nervousness (E). 6. According to the printers age showed high scored about, below 20 years were lie scale(L). aggressiveness(F), irregular life(G) 21~30years were multiple subjective symptom(I) respiratory (A), eyes and skin(B), mouth and anus(D), impulsiveness(H), mental irritability(J), depression (K), nervousness(E), and over 41 years were digestive(C). 7. Married printers scored high level on eyes and skin(B), digestive(C) and impulsivehess(H), and single printers on respiratory(A), mouth and anus(D), lie scale(L), mental irritability(J). 8. According to education shows the difference, eg high school scored higher on eyes and skin (B), mental irritability(J), depression(K), nervousness(E), collage and over scored higher on multiple subjective symptom(I ), respiratory (A), mouth and anus (D), lie scale (L), aggressiveness (F), irregular life (G), and middle school scored high on digestive (C), impulsiveness (H).

• Journal of Environmental Health Sciences
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• v.32 no.5 s.92
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• pp.412-417
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• 2006

A self-administrated non-malignant respiratory symptoms questionnaire was sent to 1,099 citizens who take subway running in Seoul city. Symptom prevalence rate was high: 70.6% of subjects reported 'chest tightness', 43.4%, 'dysphnea'; 76.2%, 'dry cough'; 49.5%, 'runny nose'; 94.4%, 'drowsiness' when they take subway. The groups responding significant higher respiratory and drowsiness symptoms were 'young passengers' (vs elderly passengers), 'the female' (vs male), 'using subway everyday' (vs often), 'using subway for rush-hour time' (vs other than rush-hour), 'using transfer subway' (no transfer), 'using underground track' (vs ground track). Logistic. regression model was employed to find personal and subway characteristics affecting non-malignant respiratory symptoms. This study concluded that respiratory diseases history such as asthma, rhinitis, sinusitis, hypersensitivity pneumonitis significantly affect 'dry cough' and 'runny nose'. Thus, passengers with respiratory diseases history shows 2.8 times greater 'dry cough' than and 3.4 times greater 'runny nose' than those passengers without respiratory diseases history felt. This results indicated that several measures have to take to protect sensitive groups such as passengers with respiratory diseases, children and elderly people. Also passenger who use to transfer shows 1.7 times higher runny nose symptoms than that passenger who do not transfer felt.

• Nutrition Research and Practice
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• v.18 no.1
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• pp.33-45
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• 2024

BACKGROUND/OBJECTIVES: Onion, particularly onion peel, is a quercetin-rich food with, anti-inflammatory and immunomodulatory effects. However, the effect of onion peel extract (OPE) in humans is unclear. Thus, the present study aimed to investigate whether OPE improves natural killer (NK) cell activity and cytokine concentration in a randomized double-blind placebo-controlled trial. SUBJECTS/METHODS: Eighty participants aged 19-64 yrs old with a white blood cell count of 4,000-10,000 cells/µL, symptoms of upper respiratory infection at least once within the previous 12 mon, and perceived stress scale (PSS) over 14 were included. Participants were randomly assigned to take either 1,000 mg/day OPE or a placebo for 8 weeks. RESULTS: Compliance were 87.4 ± 8.6% and 86.9 ± 79.0% in OPE and placebo groups. Compared to the placebo, OPE supplementation improved "Hoarseness" (P = 0.038) of the Wisconsin Upper Respiratory Symptom Survey (WURSS)-21 symptom, and stress scores (P = 0.001; 0.021) of PSS. Supplementation of OPE had no significant effect on NK cell activity and concentrations of cytokines such as interleukin (IL)-2, IL-6, IL-12, IL-1β, interferon-γ, and tumor necrosis factor-α. At baseline, the WURSS-21 symptom and PSS score (P = 0.024; 0.026) were higher in the OPE group than the placebo group. Among participants with higher than median WURSS-21 symptom score, OPE supplementation increased NK cell activity (P = 0.038). Supplementation of OPE had no significant effects on safety measurements and adverse events. CONCLUSIONS: The present study suggested that OPE supplementation improves NK cell activity in participants with moderate upper respiratory symptoms without any significant adverse effects.

• The Journal of Pediatrics of Korean Medicine
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• v.18 no.1
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• pp.77-91
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• 2004

Objective: The purpose of this study were to examine the growth pattern of weak children by measurement according to the five weak symptoms (respiratory, digestive, psycho-neurological, neuromotor, urogenital symptom). Five weak symptoms are common etiology of short stature in childhood and oriental medicine therapy is used as a treatment in short stature but the effects on height are not conclusive. Methods: This clinical study had been carried out with the 166 case (male 74, female 92) of the children aged 3 to 18 years old who visited in growth clinic of Pediatrics, Dongguk university Bundang Oriental Hospital. They were divided into 3 groups by age (3-10, 11-14, 15-18 years group) Five weak symptoms were studied to determine the association with growth stature among children by comparison with the growth stature of weak children group and normal group Results: The distribution of age showed the highest in 11-14 years(58.4%), followed by I 3-10 years (26.5%), over 15years(15%) in order. In case of male, the distribution of five weak symptoms showed the highest respiratory weak symptom(68.9%), followed by digestive(52.7%), psycho-neurological(43.2%), neuromotor(24.3%), urogenital weak symptom (143.5%) and digestive weak children's Height SDS were lower than normal children in all age groups and respiratory weak children's Height SDS were lower than normal children in age group of 3-10. In case of female, the distribution of five weak symptoms showed the highest digestive weak symptom(59.8%), followed by respiratory(52.5%), psycho-neurological(51.5%), neuromotor (35.9%), urogenital weak symptom (25%) and digestive weak children's Height SDS were lower than normal children in age group of 3-14. Other weak children Height SDS were no significant difference from normal group. Conclusions: From the above result, it was suggested that weak symptoms is cause in short stature. These data indicate that the height was correlated with respiratory, digestive weak symptom and a way to improve the weakness increased significantly height in children growth stature. Growth stature should be investigated as a new field of oriental medical treatment and more controlled, long term studies are required to classify benefits of Oriental medicine therapy in short stature.

• Journal of Technologic Dentistry
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• v.13 no.1
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• pp.37-51
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• 1991

In order to evaluate health status of dental technicians as an individual and a group, this study was conducted with Todai Health Index Questionaire on randomly sampled 277 persons(236 males and 41 females) from Aug. 20 to Oct. 6, in 1990 obtained Following conclusions were drawn. 1. Age composition of the subjects was 136 males(57.6%) in the age of 20$\sim$29 and 28 females(68.3%) in the age of 20$\sim$24. As for working places, 215 males(91.1%) and 38 females (92.7%) were working for dental laboratories and rest of them were at clinics and hospitals. In working years, male technicians who have been working for 5$\sim$10 years amounted to 80 (33.8%) and 12 females(29.3%) were working for 1$\sim$3years. 2. Responses to psychosomatic subjective symptom complaints rated as the highest in multiple subjective symptom(males : 40.00%, females : 41.98%) and those in physical items and mental irritability(male : 24%, female : 25%) and in mental items came next in order. The rate of complaint in depression was higher in female group than in male group (p<0.05). 3. Resonses to psychosomatic subjective symptom complaints in male group were high in the age of 20$\sim$29 and in the age of 20$\sim$24 in female group. The rates of complaint were higher in multiple subjective symptom, respiratory, eye and skin(p<0.05) and digestives(p<0.01) complaints. 4. Responses to psychosomatic subjective symptom complaints were higher among persons working at dental laboratories than at other working places : dental clinics and hospitals in all the items except for respiratory, depression and aggressiveness. Rates of complaints in eye and skin showed significant difference between working places(p<0.05). 5. Those who are engaged in polishing part tended to complain more about psychosomatic subjective symptoms. 6. The higher the level of education is the more they complained the psychosomatic subjective symptoms both in male and female group. In the difference of complaint respones, male group showed high rates of complaint in depression and female group in aggressiveness(p<0.05). 7. Responses to psychosomatic complaints by the length of working service were moderate in males who were working less than 10 years, and they decreased after 10 years of service. Females showed the highest response rate in the group of 3$\sim$5 years service and the lowest response in the group of 5 years service. Male complained more in aggressiveness and female in respiratory and aggressiveness(p<0.05). 8. Responses to psychosomatic subjective symptom complaint varied according to working hours of a day both in male and female group, showing high complaint rates in multiple subjective symptom, respiratory, eye and skin, mouth and anus, digestive, mental irritability and irregular life in male group(p<0.05).

• Journal of Veterinary Clinics
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• v.24 no.2
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• pp.150-153
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• 2007

The aim of this study was to investigate the prevalence of bovine viral diarrhea virus (BVDV) infection in Chonbuk province. Blood samples were taken from 92 korean calves to determined their serological status against BVDV, Capture enzyme-linked immunosorbent assay (ELISA) was used to test for antigen. The number of seropositive calves ranged from 3.3% to 12.9%. Antigens against BVDV were detected in 3.3% of healthy calves, 6.4% of digestive symptom calves, 12.9% of respiratory symptom calves, respectively. Sex and age of calves had no significant differences on the prevalence of BVDV. The results indicate that transmission of BVDV may have become exposed as a result of contact with acute infected or persistently infected cattle.

• Tuberculosis and Respiratory Diseases
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• v.79 no.4
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• pp.241-247
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• 2016

Bronchodilators are the cornerstone of symptomatic chronic obstructive pulmonary disease (COPD) treatment. They are routinely recommended for symptom reduction, with a preference of long-acting over short-acting drugs. Bronchodilators are classified into two classes based on distinct modes of action, i.e., long-acting antimuscarinics (LAMA, once-daily and twice-daily), and long-acting ${\beta}2$-agonists (LABA, once-daily and twice-daily). In contrast to asthma management, evidence supports the efficacy of both classes of long-acting bronchodilators as monotherapy in preventing COPD exacerbations, with greater efficacy of LAMA drugs versus LABAs. Several novel LAMA/LABA fixed dose combination inhalers are currently approved for COPD maintenance treatment. These agents show superior symptom control to monotherapies, and some of these combinations have also demonstrated superior efficacy in exacerbation prevention versus monotherapies, or combinations of inhaled corticosteroids plus LABA. This review summarizes the current data on clinical effectiveness of bronchodilators alone or in combination to prevent exacerbations of COPD.

• Journal of Preventive Medicine and Public Health
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• v.30 no.4 s.59
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• pp.752-763
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• 1997

To evaluate the effect of manganese on the respiratory system, we investigated the respiratory symptoms of 63 male workers exposed to, fume containing manganese (Mn), iron (Fe) and silica (Si), and compared them with those of 66 male workers not exposed to the fume in a manganese alloy smelting factory. The prevalence ratios of the seven respiratory symptoms were not different between two groups. The presence of any respiratory symptom was not related with the age, duration of employment, smoking status of workers, and exposure to fume. In furnace workers, it was not related with the airborne Mn, Fe, and Si concentration in the total or respirable fume. Airborne Mn concentrations of all 4 furnaces in the respirable fume were below $1mg/m^3$. There were two suspicious cases of pneumoconiosis among furnace workers and one definite case(1/2) among casting workers who were not exposed to fume. The above results suggest that the exposure to the low airborne Mn concentration is not related with respiratory symptoms and pneumoconiosis. However, it is necessary to study the respiratory effects of Mn using the symptom questionnaire with consideration of the severity and persistence, of symptoms and the time interval from exposure.

• Journal of Preventive Medicine and Public Health
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• v.27 no.2 s.46
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• pp.313-325
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• 1994

A cross-sectional study was conducted in an effort to investigate the effect of air pollution on respiratory symptoms. Two groups of female aged more than 20 living in the unpolluted rural area of Taebul (n=159) and urban area of Taegu (n=140) were selected. The ATS-DLD-78 questionnaire was translated into Korean and administered with minor modification. The proportion of smoker was less than 1% in both area. Exposure to smoking and higher educational level were more frequent in Taegu. Age-adjusted prevalence rates of 'chronic cough', 'chronic sputum', 'wheezing', and 'dyspnea' were higher in Taegu than in Taebul. In particular, the prevalence rate of 'chronic sputum' in Taegu was found to be higher, which was statistically significant. Exposure to smoking and education level were not concerned with all respiratory symptom prevalence rates. In conclusion, this study Indicates that an urban factor is related to the rates of respiratory symptoms in Korea.