• Journal of the Korean Society of Propulsion Engineers
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• v.21 no.1
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• pp.26-35
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• 2017

The high-cycle fatigue cracking and the resonance generated in operation of a centrifugal compressor are main cause of the impeller damage. In order to prevent the damage, the impeller is designed or modified to have sufficient strength to withstand the operating condition. The damage prevent design will lead to a change of the flow condition and the performance characteristics of the compressor. In this study, the computational analysis were performed to identify the flow and the performance characteristics. The cases are a scalloped and a increased the blade thickness models with a closed type impeller. As the analysis results, the value of head coefficient and total to total efficiency for the increased the blade thickness model was decreased by each 0.5% and 0.1% than the values of the baseline model. Each value for the scalloped model was increased by 0.4% and was decreased by 1.6%.

• Nuclear Engineering and Technology
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• v.53 no.10
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• pp.3344-3351
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• 2021

The Rare Isotope Science Project was launched in 2011 in Korea toward constructing the Rare isotope Accelerator complex for ON line experiments (RAON). RAON will house several experimental systems, including the Muon Spin Rotation/Relaxation/Resonance (μSR) facility in High Energy Experimental Building B. This facility will use 600-MeV protons with a maximum current of 660 pμA and beam power of 400 kW. The key μSR features will facilitate projects related to condensed-matter and nuclear physics. Typical experiments require a few million surface muons fully spin-polarized opposite to their momentum for application to small samples. Here, we describe the design of a muon transport beam line for delivering the requisite muon numbers and the electromagnetic-component specifications in the μSR facility. We determine the beam-line configuration via beam-optics calculations and the transmission efficiency via single-particle tracking simulations. The electromagnet properties, including fringe field effects, are applied for each component in the calculations. The designed surface-muon beamline is 17.3 m long, consisting of 2 solenoids, 2 dipoles affording 70° deflection, 9 quadrupoles, and a Wien filter to eliminate contaminant positrons. The average incident-muon flux and spin rotation angle are estimated as 5.2 × 10⁶ μ⁺/s and 45°, respectively.

• Korean Chemical Engineering Research
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• v.59 no.4
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• pp.493-502
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• 2021

We prepared and investigated a biosynthesized nanoparticulate system with high adsorption and release capacity of letrozole. Silver nanoparticles (AgNPs) were biosynthesized using olive leaf extract. Cysteine was capped AgNPs to increase the adsorption capacity and suitable interaction between nanoparticles and drug. Morphology and size of nanoparticles were confirmed using transmission electron microscopy (TEM). Nanoparticles were spherical with an average diameter of less than 100 nm. Cysteine capping was successfully confirmed by Fourier transform infrared resonance (FTIR) spectroscopy and elemental analysis (CHN). Also, the factors of letrozole adsorption were optimized and the linear and non-linear forms of isotherms and kinetics were studied. Confirmation of the adsorption data of letrozole by cysteine capped nanoparticles in the Langmuir isotherm model indicated the homogeneous binding site of modified nanoparticles surface. Furthermore, the adsorption rate was kinetically adjusted to the pseudo-second-order model, and a high adsorption rate was observed, indicating that cysteine coated nanoparticles are a promising adsorbent for letrozole delivery. Finally, the kinetic release profile of letrozole loaded modified nanoparticles in simulated gastric and intestinal buffers was studied. Nearly 40% of letrozole was released in simulated gastric fluid with pH 1.2, in 30 min and the rest of it (60%) was released in simulated intestinal fluid with pH 7.4 in 10 h. These results indicate the efficiency of the cysteine capped AgNPs for adsorption and release of drug letrozole for breast cancer therapy.

• Nano
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• v.13 no.11
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• pp.1850127.1-1850127.13
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• 2018

Bi metal deposited on $Bi_2MoO_6$ composite photocatalysts have been successfully synthesized via a simple reduction method at room temperature with using $NaBH_4$ as the reducing agent. The photocatalytic activity of the composite was evaluated by degradation of rhodamine B (RhB) and bisphenol A (BPA) solution under visible light. The rate constant of $Bi/Bi_2MoO_6$ composite to RhB is 10.8 times that of $Bi_2MoO_6$, and the degradation rate constant of BPA is 6.9 times of that of $Bi_2MoO_6$. Nitrogen absorption-desorption isotherm proved that the increase of specific surface area is one of the reasons for the improvement of photocatalytic degradation activity of $Bi/Bi_2MoO_6$ composites. The higher charge transfer efficiency of $Bi/Bi_2MoO_6$ is found through the characterization of the photocurrent and impedance, which are attributed to the surface plasmon resonance (SPR) effect produced by the introduction of the metal Bi monomer in the composite. Free radical capture experiments proved that cavitation is the main active species. Based on the above conclusions, a possible mechanism of photocatalytic degradation is proposed.

• Korean Journal of Materials Research
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• v.29 no.3
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• pp.155-159
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• 2019

Surface plasmon resonance is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident light. In particular, when light transmits through the metallic microhole structures, it shows an increased intensity of light. Thus, it is used to increase the efficiency of devices such as LEDs, solar cells, and sensors. There are various methods to make micro-hole structures. In this experiment, micro holes are formed using a wet chemical etching method, which is inexpensive and can be mass processed. The shape of the holes depends on crystal facets, temperature, the concentration of the etchant solution, and etching time. We select a GaAs(100) single crystal wafer in this experiment and satisfactory results are obtained under the ratio of etchant solution with $H_2SO_4:H_2O_2:H_2O=1:5:5$. The morphology of micro holes according to the temperature and time is observed using field emission - scanning electron microscopy (FE-SEM). The etching mechanism at the corners and sidewalls is explained through the configuration of atoms.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.11
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• pp.851-856
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• 2018

In this study, we analyze the characteristics of wireless power transfer(WPT) based on magnetic resonance in an underwater environment and propose an equivalent model suitable for underwater WPT. The proposed underwater WPT equivalent model is constructed by expanding the free-space WPT T-model reflecting characteristics change according to media. Considering the water salinity, we propose a method to extract the parameters of the proposed model based on the S parameters. To verify the proposed model, a 6.78-MHz underwater WPT system was constructed and compared with the predicted power transfer efficiency of the model. As a result, it was confirmed that the proposed model predicts the variation of characteristics with an average error of less than 3 %.

• The Journal of Internal Korean Medicine
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• v.40 no.1
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• pp.126-135
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• 2019

Background: Because of fear of reoperation and low efficiency, some patients with failed back surgery syndrome (FBSS) opt for Korean medicine treatment. Gold standard treatment is not present for FBSS, therefore both surgical and non-surgical treatment are possible. Studies of Korean conservative medicine for FBSS had a short duration of treatment and mainly pre- and post-treatment comparisons. And case of female patients who have worsened after childbirth is rare. The purpose of this study was to report long-term follow-up and rare cases of FBSS. Case summary: A 33-year-old female patient diagnosed with lumbar disc herniation complained with low back pain and radicular pain in the left leg after surgery in 2011. Acupuncture and decoction (Cheongpa-jeon, GCSB-5) were administered to her twice a day for about 6 years and 6 months. The patient's complaints improved with each hospitalization, and Magnetic Resonance Imaging (MRI) showed a slight decrease in the size of the recurrent disc (L4/5) and a newly developed disc (L5/S1) that had deteriorated after delivery. Conclusion: Korean medicine could be used to manage the pain of lumbar spine FBSS patients for 6-7 years and to alleviate lumbago after delivery.

• Journal of Convergence for Information Technology
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• v.12 no.2
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• pp.142-148
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• 2022

In this paper, the weight reduction design of the yaw gearbox for wind turbine was performed through the finite element analysis method, and the stability was checked by performing the critical speed analysis. The weight reduction product can improve engine efficiency, save parts materials, and earn economic benefits. The yaw gearbox is lightweighted with the goal of achieving a safety rate of 1.3 or higher for wind turbine as indicated by IEC61400-1. In order to reduce the weight of the carrier, a topology optimization method was performed. The safety factor was verified by performing finite element analysis on the carrier. In addition, the housing and carrier were modeled using the finite element method, and the gear train was modeled using MASTA. For the yaw gearbox, the housing and carrier FE model and the gear train model were connected by the partial structural synthesis method to perform the rotational vibration analysis. Vibration excitation sources are mass unbalance and gear mesh frrequemcy, and as a result of the critical speed analysis, it was found that there was no resonance within the operating speed range.

• International Journal of Computer Science & Network Security
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• v.22 no.12
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• pp.245-251
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• 2022

In this paper, a high gain, broadband planar vivaldi antenna (PVA) by utilizing a broadband stripline feed is developed for wireless communication for IoT systems. The suggested antenna is designed by attaching a tapered-slot construction to a typical vivaldi antenna, which improves the antenna's radiation properties. The PVA is constructed on a low-cost FR4 substrate. The dimensions of the patch are 1.886λ₀×1.42λ₀×0.026λ₀, dielectric constant Ɛ_r=4.4, and loss tangent δ=0.02. The width of the feed line is reduced to improve the impedance bandwidth of the antenna. The computed reflection coefficient findings show that the suggested antenna has a 46.2% wider relative bandwidth calculated at a 10 dB return loss. At the resonance frequencies of 6.5 GHz, the studied results show an optimal gain of 5.82 dBi and 85% optimal radiation efficiency at the operable band. The optometric analysis of the proposed structure shows that the proposed antenna can achieve wide enough bandwidth at the desired frequency and hence make the designed antenna appropriate to work in satellite communication and medical internet of things (M-IoT) healthcare applications.

• Biomedical Science Letters
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• v.29 no.4
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• pp.211-219
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• 2023

Caffeic acid phenethyl ester (CAPE) is an active component of propolis obtained from honeybee hives. CAPE possesses anti-mitogenic, anti-carcinogenic, anti-inflammatory, and immunomodulatory activities in diverse systems, which know as displays antioxidant activity and inhibits lipoxygenase activities, protein tyrosine kinase, and nuclear factor kappa B (NF-κB) activation. This study aimed to investigate the effect of CAPE on lipopolysaccharide (LPS)-induced human neutrophil phagocytosis. Human neutrophils were cultured with various concentrations of CAPE (1, 10, and 100 µM) with or without LPS. The pro-inflammatory proteins (tumor necrosis factor-alpha [TNF-α], interleukin [IL]-6 and IL-8) levels were measured after 4 h incubation. To investigate the intracellular signaling pathway, we measured the levels of mitogen-activated protein kinases (MAPK), including phosphorylation of p38, extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) and c-Jun N-terminal kinase (JNK). Next, to evaluate the potential phagocytosis, neutrophils were labeled with iron particles of superparamagnetic iron oxide nanoparticles (SPIONs, 40 nm) for 1 h in culture medium containing 5 mg/mL of iron. The labeling efficiency was determined by Prussian blue staining for intracellular iron and 3T-wighted magnetic resonance imaging. CAPE decreased the activation of intracellular signaling pathways, including ERK1/2 and c-Jun, and expression of pro-inflammatory cytokines, including TNF-α and IL-6, but had no effect on the signaling pathways of p38 and cytokine IL-8. Furthermore, images obtained after mannan-coated SPION treatment suggested that CAPE induced significantly higher signal intensities than the control or LPS group. Together, these results suggest that CAPE regulates LPS-mediated activation of human neutrophils to reduce phagocytosis.