• Title/Summary/Keyword: residual condition

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Effects of Pefloxacin Grinding on Pharmacokinetic Parameter in Korean Rockfish (조피볼락에서 Pefloxacin의 미분쇄가 약물동력학 Parameters에 미치는 영향)

  • 임영근;양영환;김진우;손상규;심경희;김유정;정한영;최우식;야마모토케이지
    • Journal of Life Science
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    • v.9 no.3
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    • pp.241-247
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    • 1999
  • Antibiotics have been routinely used to control the disease of farm-raised animals in the aquaculture facilities without any criterion based on a pharmacokinetic study. This lack of information on the effective usage of antibiotics would have brought the farmers to use excessive and/or less dosages, causing the advent of drug-resistant bacteria as well as economic loss and possible contamination of the local farming area. Until recently, few studies on a detailed manual for the antibiotic usage including chemotherapy procedure, dosage, and treatment schedule of the aquatic antibiotics have been conducted throughout the world. To the worse, there is no available criterion for optimal usage of aquatic antibiotics to control diseases in aquatic farms in this country because every country has its own aquacultural system. Therefore, based on the previous studies on the usage of the various antibiotics, our studies are to focus on the development of optimal method for the detection of various antibiotics on the fate of antibiotics applied to the fish, including absorption, circulation, and secretion physiology. Pharmacokinetic study were to sep up the optimal detective condition against residual antibiotics of fish by HPLC. The grinding pefloxacin for 15 min is most effective in dissolution test and pharmacokinetic parameters. Pharmacokinetic parameters were satisfactory for 15 min-grinding products and they can be explained as one-compartment model.

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Constraint Analysis and Reduction of Over-Constraints for Tolerance Design of Assemblies - A Case Study of Ball Valve Design (조립체 공차설계를 위한 제약해석과 과잉제약 개선 - 볼밸브 설계 사례연구)

  • Park, Jun Il;Yim, Hyunjune
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.8
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    • pp.669-681
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    • 2016
  • Mechanical designers often make mistakes that result in unwanted over-constraints, causing difficulty in assembly operations and residual stress due to interference among parts. This study is concerned with detection and elimination of over-constraints. Screw theory is a general method that is used for constraint analysis of an assembly and motion analysis of a mechanism. Mechanical assemblies with plane-plane, pin-hole, and pin-slot constraint pairs are analyzed using screw theory to illustrate its utility. As a real-world problem, a ball valve design is analyzed using the same method, and several unwanted over-constraints are detected. Elimination measures are proposed. Nominal dimensions of some parts are adjusted, and dimensions and tolerances of the pins and holes are modified using the virtual condition boundary concept. The revised design is free of over-constraints. General procedure for applying screw theory to constraint analysis is established and demonstrated; it will contribute to improving quality of assembly designs.

Observed Quasi-steady Kinetics of Yeast Cell Growth and Ethanol Formation under Very High Gravity Fermentation Condition

  • Chen Li-Jie;Xu Ya-Li;Bai Feng-Wu;Anderson William A.;Murray Moo-Young
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.10 no.2
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    • pp.115-121
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    • 2005
  • Using a general Saccharomyces cerevisiae as a model strain, continuous ethanol fermentation was carried out in a stirred tank bioreactor with a working volume of 1,500 mL. Three different gravity media containing glucose of 120, 200 and 280 g/L, respectively, supplemented with 5 g/L yeast extract and 3 g/L peptone, were fed into the fermentor at different dilution rates. Although complete steady states developed for low gravity medium containing 120 g/L glucose, quasi-steady states and oscillations of the fermented parameters, including residual glucose, ethanol and biomass were observed when high gravity medium containing 200 g/L glucose and very high gravity medium containing 280 g/L glucose were fed at the designated dilution rate of $0.027\;h^{-1}$. The observed quasi-steady states that incorporated these steady states, quasi-steady states and oscillations were proposed as these oscillations were of relatively short periods of time and their averages fluctuated up and down almost symmetrically. The continuous kinetic models that combined both the substrate and product inhibitions were developed and correlated for these observed quasi-steady states.

Evaluation on Mechanical Properties of Ultra High Strength Concrete with Heating and Loading (고온가열 및 하중재하에 따른 초고강도 콘크리트의 역학적 특성 평가)

  • Kim, Min-Jung;Choe, Gyeong-Cheol;Yoon, Min-Ho;Ham, Eun-Young;Miyauchi, Hiroyuki;Kim, Gyu-Yong
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.11a
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    • pp.34-35
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    • 2013
  • In this study, the ultra high strength concrete which have 80, 130, 180MPa took the heat from 20℃ to 700℃ and the 0, 20% stress in normal condition's to evaluate stress-strain, residual compressive strength and thermal expansion deformation were evaluated. The heating speed of specimen was 0.77℃/min 20~50℃, 50℃ before the target temperature, and the other interval's heating speed was 1℃/min. As a result, the stress-strain curve of non-load specimen showed the liner behavior at high temperature when the specimen's strength increased more. If ultra high strength concrete got loads, its compressive strength tended to decrease different from the normal strength concrete. The thermal expansion deformation was expanded from a vitrification of quartz over 500℃. however, over the 600℃, it was shrinked because of the dehydration of the combined water.

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Sorption behavior of slightly reduced, three-dimensionally macroporous graphene oxides for physical loading of oils and organic solvents

  • Park, Ho Seok;Kang, Sung Oong
    • Carbon letters
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    • v.18
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    • pp.24-29
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    • 2016
  • High pollutant-loading capacities (up to 319 times its own weight) are achieved by three-dimensional (3D) macroporous, slightly reduced graphene oxide (srGO) sorbents, which are prepared through ice-templating and consecutive thermal reduction. The reduction of the srGO is readily controlled by heating time under a mild condition (at 1 10−2 Torr and 200℃). The saturated sorption capacity of the hydrophilic srGO sorbent (thermally reduced for 1 h) could not be improved further even though the samples were reduced for 10 h to achieve the hydrophobic surface. The large meso- and macroporosity of the srGO sorbent, which is achieved by removing the residual water and the hydroxyl groups, is crucial for achieving the enhanced capacity. In particular, a systematic study on absorption parameters indicates that the open porosity of the 3D srGO sorbents significantly contributes to the physical loading of oils and organic solvents on the hydrophilic surface. Therefore, this study provides insight into the absorption behavior of highly macroporous graphene-based macrostructures and hence paves the way to development of promising next-generation sorbents for removal of oils and organic solvent pollutants.

Characteristics of $CU(InGa)Se_2$Thin Film Solar Cells with Deposition Condition of Mo Electrode (몰리브덴 전극의 형성조건에 따른 $CU(InGa)Se_2$ 박막 태양전지의 특성)

  • Kim, Seok-Gi;Han, Sang-Ok
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.50 no.12
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    • pp.607-613
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    • 2001
  • Molybdenum thin films were deposited on the soda lime glass(SLG) substrates by direct-current planar magnetron sputtering, with a sputtering power density of $4.44W/cm^2$. The working pressure was varied from 0.5 mtorr to 20 mtorr to gain a better understanding of the effect of sputtering pressure on the morphology and microstructure of the Mo film. Thin films of $CU(InGa)Se_2$ (CIGS) were deposited on the Mo-coated glass by three stage co-evaporation process. The highest efficiency device was obtained at the maximum value of the tensive stress. The morphology of Mo-coated films were examined by using scanning electron microscopy The film's microstructure, such as the preferred orientation, the full width at half-maximum(FWHM), and the residual intrinsic stress were examined by X-ray diffraction.

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The Material Analyses and the Behavior Characteristics according to RCD Discloser (누전차단기 폭로에 따른 동작 특성 및 재료 분석)

  • Han, Woon-Ki;Kim, Hyang-Kon;Gil, Hyung-Jun;Lee, Ki-Hyun;Choi, Chung-Seog
    • Proceedings of the KIEE Conference
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    • 2005.07c
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    • pp.2019-2021
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    • 2005
  • This paper describes the cut off time and the current characteristics of virgin RCDs and deteriorated ones in the seashore. The RCDs(Residual Current Protective Devices) are used for protecting the human body from electrical shock and for preventing facility accidents. According to the Korean standards, the RCDs are installed in panel boards. When RCDs are installed outside, they must be enclosed inside waterproof cases. In the case that RCOs are employed at temporary power sites and electrical facilities on the road, they are exposed to the external environment. As a result, the RCDs deteriorated in the seashore for 3 months showed high failure rate, while the virgin RCDs all complied with Korean Standard. Considering that the RCDs are used under exposed condition outside, the reliance of RCDs must be ensured by modifying the related regulations and codes and by developing Improved models advanced in their performance.

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A Study on the CAI Combustion Characteristics and Stratified Combustion to Extend the Operating Region Using Direct Injection Gasoline Engine (직접분사식 가솔린 엔진을 이용한 CAI 연소특성 및 운전영역 확대를 위한 성층 연소 특성에 관한 연구)

  • Lee, Chang-Hee;Choi, Young-Jong;Lim, Kyoung-Bin;Lee, Ki-Hyung
    • Transactions of the Korean Society of Automotive Engineers
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    • v.14 no.5
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    • pp.25-31
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    • 2006
  • Controlled Auto Ignition(CAI) combustion has great potential in achieving significant increase in engine efficiency, while simultaneously reducing exhaust emissions. The process itself involves the auto ignition and subsequent simultaneous combustion of a premixed charge. In this study, NVO(Negative Valve Overlap) system was applied to a CAI engine in order to use residual gas. The fuel was injected directly to the cylinder under the high temperature condition resulting from heating the intake port to initiate CAI combustion. This paper introduced the valve timing strategy and experimental set-up. From this study, the effect of engine speed and valve timing on CAI combustion and exhaust emissions was clarified. In addition, stratified charge method was used to extend CAI operating region.

A Study on the Internal Grinding to Improving the Grinding Efficiency (내면연삭(內面硏削)의 가공능률향상(加工能率向上)에 관한 연구)

  • Kim, G.H.;Kang, J.H.;An, S.O.;Park, J.K.
    • Transactions of the Korean Society of Automotive Engineers
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    • v.2 no.6
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    • pp.87-93
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    • 1994
  • This paper describes on the establishment of an optimal internal grinding conditions for the purpose of improving the grinding efficiency against to the high-speed grinding. Through the fundamental grinding tests for the brittle and hardened material, we are concluded that high-speed internal grinding is effective to improve the grinding accuracy as well as the grinding efficiency. The obtained results are as follows: (1) Under the speed ratio $(V_w/V_g)$ is constant, it is possible to increase the grinding efficiency with satifying the constraint conditions. (2) Increasing the wheel velocity, surface roughness and out-roundness are improved. (3) Under the wheel depth of cut is constant and increasing the speed ratio, workpiece residual stress is decreased. The described method, in this paper, is capable of determining the optimum internal grinding conditions taking into account some constraint conditions, and practical algorithm for optimum internal grinding conditions are presented.

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Context-Based Minimum MSE Prediction and Entropy Coding for Lossless Image Coding

  • Musik-Kwon;Kim, Hyo-Joon;Kim, Jeong-Kwon;Kim, Jong-Hyo;Lee, Choong-Woong
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 1999.06a
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    • pp.83-88
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    • 1999
  • In this paper, a novel gray-scale lossless image coder combining context-based minimum mean squared error (MMSE) prediction and entropy coding is proposed. To obtain context of prediction, this paper first defines directional difference according to sharpness of edge and gradients of localities of image data. Classification of 4 directional differences forms“geometry context”model which characterizes two-dimensional general image behaviors such as directional edge region, smooth region or texture. Based on this context model, adaptive DPCM prediction coefficients are calculated in MMSE sense and the prediction is performed. The MMSE method on context-by-context basis is more in accord with minimum entropy condition, which is one of the major objectives of the predictive coding. In entropy coding stage, context modeling method also gives useful performance. To reduce the statistical redundancy of the residual image, many contexts are preset to take full advantage of conditional probability in entropy coding and merged into small number of context in efficient way for complexity reduction. The proposed lossless coding scheme slightly outperforms the CALIC, which is the state-of-the-art, in compression ratio.