• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.781-782
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• 2005

• Biomolecules & Therapeutics
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• v.25 no.6
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• pp.659-664
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• 2017

Although lisdexamfetamine is used as a recreational drug, little research exists regarding its potential for dependence or its precise mechanisms of action. This study aims to evaluate the psychoactivity and dependence profile of lisdexamfetamine using conditioned place preference and self-administration paradigms in rodents. Additionally, biochemical techniques are used to assess alterations in the dopamine levels in striatal synaptosomes following administration of lisdexamfetamine. Lisdexamfetamine increased both conditioned place preference and self-administration. Moreover, after administration of the lisdexamfetamine, dopamine levels in the striatal synaptosomes were significantly increased. Although some modifications should be made to the analytical methods, performing high performance liquid chromatography studies on synaptosomes can aid in predicting dependence liability when studying new psychoactive substances in the future. Collectively, lisdexamfetamine has potential for dependence possible via dopaminergic pathway.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.05a
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• pp.138-138
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• 2002

In recent years, the safety of sunscreens has been challenged based on the reports of its adverse effect on users; dermatitis, allergic contact dermatitis, photoallergic contact dermatitis. To investigate a correlation between sun protection factor (SPF) and the safety of sunscreens, we measured in vitro SPF index using homosalate as a standard and examined the toxicity tests on cosmetics; primary and cumulative skin irritation tests, ocular irritation test, and skin sensitization test.(omitted)

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.195-195
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• 2002

In recent years, the safety of sunscreens has been challenged based on the reports of its adverse effect on users; dermatitis, allergic contact dermatitis, photoallergic contact dermatitis. To investigate a correlation between sun protection factor (SPF) and the safety of sunscreens, we measured in vitro SPF index using homosalate as a standard and examined the toxicity tests on cosmetics; primary skin irritation tests, ocular irritation test, and skin sensitization test.(omitted)

• Journal of the Korean Society of Safety
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• v.25 no.1
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• pp.72-78
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• 2010

Laboratory accidents have happened incidently. However, laboratory safety management has been out of concerns for a long time. At last, the Korean government established an act called Establishment of safe environment of laboratories in 2005. To support the act and to establish policies on laboratory safety management，a national-wide survey was conducted for the 74 research organizations sampled and their 201 laboratories. For the survey, a safety management checklist with 114 items grouped into 20 categories was developed By using this checklist, safety expert groups investigated the laboratories and evaluated them on the five-point Likert scale. A statistical analysis was conducted to compare the safety management status between different research organization types and between different research fields. The resultsmanaw that the universities are in significant lower level on safety institution and safety education than the public research organizations and theare poration research organizations. In terms of research field, chemistry/chemical engineering laboratories generallymanaw higher level compared with theaothers. Conversely, biology/life science laboratories marked low levels in a number of checklist items.

• 한국가스학회:학술대회논문집
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• 2007.04a
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• pp.201-205
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• 2007

• Proceedings of the KIEE Conference
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• 2006.07a
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• pp.454-455
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• 2006

This paper describes the safety assessment algorithm applied for the underground electrical utilities submerged due to flooding. In implementing the algorithm, several factors pertaining to utility safety were introduced into the process flow, and safety weight was given to each factor. It is considered that this algorithm can ensure the safety of electrical utilities installed underground when they are submerged.

• Proceedings of the Korean Nuclear Society Conference
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• 2004.10a
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• pp.211-212
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• 2004

• Proceedings of the Korean Nuclear Society Conference
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• 2004.10a
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• pp.163-164
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• 2004

• Journal of the Korean Society of Safety
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• v.38 no.5
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• pp.58-64
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• 2023

This study aims to analyze the differences between the safety leadership of the laboratory director, safety climate, safety motivation, and safety behavior of research workers based on whether they have participated in the certification system for exemplary laboratories in safety management (CSEL). An online survey was conducted among research workers to analyze the effect of the CSEL. The independent variables used in the survey were participation and non-participation in the CSEL, while the dependent variables were the safety leadership of the laboratory director, safety climate, safety motivation, and safety behavior of research workers. The results demonstrate that the group that participated in the CSEL had statistically significantly higher levels of safety leadership, safety climate, safety motivation, and safety behavior than the one that did not do so. Therefore, it can be concluded that the CSEL has a positive impact on the establishment of an autonomous safety management system in a laboratory by improving the safety culture and safety behavior of research workers. Further, the extrinsic factors, which are subfactors for safety motivation, did not reflect a significant difference between the group that participated in the CSEL and the one that did not. Thus, a reward system for research workers with excellent safety activities should be operated by research institutes since it is necessary to strengthen the intrinsic safety motivation of individual research workers which can be strengthened by compensation. The government should consider measures such as providing research incentives to researchers participated in CSEL.