• 제목/요약/키워드: reproduction efficiency

검색결과 293건 처리시간 0.031초

Production of Transgenic Mice Secreting a C. thermocellum Cellulase D in the Pancreas

  • Park, Jung-Ok;Lee, Eun-Ju;Kim, Myoung-Ok;Kim, Sung-Hyun;Park, Jun-Hong;Cho, Kyung-In;Nam, Myung-Su;Park, Hum-Dai;Ryoo, Zae-Young
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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    • pp.94-94
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    • 2002
  • Increasing competition in the livestock industry has forced producers to cut costs by adopting new technologies aimed out increasing production efficiency. Non-ruminant livestock do not express fibrolytic enzymes. The major plant cell wall components of cereals, primarily β-glucans and arabinoxylans, form gel-like structures in the small intestines that trap nutrients. The viscous polysaccharides can also cause severe gastrointestinal disorders. (omitted)

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Co-treatment with Demecolcine and BMI-1026, a Potent cdk1 Inhibitor, Induces the Enucleation of Murine Oocytes

  • Choi, Tae-Saeng
    • Reproductive and Developmental Biology
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    • 제34권1호
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    • pp.15-19
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    • 2010
  • Oocyte enucleation is essential for somatic cell nuclear transfer (SCNT) in the production of cloned animals or embryonic stem cells from adult somatic cells. Most studies of oocyte enucleation have been performed using micromanipulator-based techniques, which are technically demanding, time-consuming, and expensive. Several recent studies have used chemical-induced oocyte enucleation; however, each has been plagued by low efficiency and toxicity. In this study, I found that the co-treatment of murine oocytes with demecolcine and BMI-1026, a potent cdk1 inhibitor, resulted in a high enucleation rate (97%). This method is entirely independent of a micromanipulator and is suitable for the large-scale production of enucleated oocytes. This new method of enucleation will be useful in SCNT and in the development of handmade cloning techniques.

Evaluation of Advanced Structure-Based Virtual Screening Methods for Computer-Aided Drug Discovery

  • Lee, Hui-Sun;Choi, Ji-Won;Yoon, Suk-Joon
    • Genomics & Informatics
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    • 제5권1호
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    • pp.24-29
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    • 2007
  • Computational virtual screening has become an essential platform of drug discovery for the efficient identification of active candidates. Moleculardocking, a key technology of receptor-centric virtual screening, is commonly used to predict the binding affinities of chemical compounds on target receptors. Despite the advancement and extensive application of these methods, substantial improvement is still required to increase their accuracy and time-efficiency. Here, we evaluate several advanced structure-based virtual screening approaches for elucidating the rank-order activity of chemical libraries, and the quantitative structureactivity relationship (QSAR). Our results show that the ensemble-average free energy estimation, including implicit solvation energy terms, significantly improves the hit enrichment of the virtual screening. We also demonstrate that the assignment of quantum mechanical-polarized (QM-polarized) partial charges to docked ligands contributes to the reproduction of the crystal pose of ligands in the docking and scoring procedure.

Animal Breeding: What Does the Future Hold?

  • Eisen, E.J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제20권3호
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    • pp.453-460
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    • 2007
  • An overview of developments important in the future of animal breeding is discussed. Examples from the application of quantitative genetic principles to selection in chickens and mice are given. Lessons to be learned from these species are that selection for production traits in livestock must also consider selection for reproduction and other fitness-related traits and inbreeding should be minimized. Short-term selection benefits of best linear unbiased predictor methodology must be weighed against long-term risks of increased rate of inbreeding. Different options have been developed to minimize inbreeding rates while maximizing selection response. Development of molecular genetic methods to search for quantitative trait loci provides the opportunity for incorporating marker-assisted selection and introgression as new tools for increasing efficiency of genetic improvement. Theoretical and computer simulation studies indicate that these methods hold great promise once genotyping costs are reduced to make the technology economically feasible. Cloning and transgenesis are not likely to contribute significantly to genetic improvement of livestock production in the near future.

유기발광 다이오드의 전류 가속 수명 평가법에 대한 연구 (A study on die method of organic light emission diod's current accelerated life test)

  • 최영태;조재립
    • 한국품질경영학회:학술대회논문집
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    • 한국품질경영학회 2009년도 추계학술대회
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    • pp.234-240
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    • 2009
  • The growing mobile products market is expected energy efficiency. So product design is more important focusing on reducing power consumption than improving technology of color sense. A Organic light emission diode is in limelight of the best display to satisfy market expectation. A Organic light emission diode is achieved low power consumption, pixel response which was fast for its time, high contrast of brightness and wide color reproduction raio. Therefore there is a fierce competition for the organic light emission diode development between a country and another country over business. The technical value's life is short because of a fierce development competition, and there is little probability that technical success become business success. In this study, the purpose is reduce the time for life test by accelerated current and it can do production possible design by accelerated life model in design phase.

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Stimulation of Spermiation by Human Chorionic Gonadotropin and Carp Pituitary Extract in Grass Puffer, Takifugu niphobles

  • Goo, In Bon;Park, In-Seok;Gil, Hyun Woo;Im, Jae Hyun
    • 한국발생생물학회지:발생과생식
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    • 제19권4호
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    • pp.253-258
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    • 2015
  • Spermiation was stimulated in the mature grass puffer, Takifugu niphobles, with an injection of human chorionic gonadotropin (HCG) or carp pituitary extract (CPE). Spermatocrit and sperm density were reduced, but milt production was increased in both the HCG and CPE treatment groups relative to those in the control group (P < 0.05). These results should be useful for increasing the fertilization efficiency in grass puffer breeding programs.

Antennal Sensory Organs in the Female Millipede Orthomorphella pekuensis (Polydesmida: Paradoxosomatidae)

  • Chung, Kyung-Hwun;Moon, Myung-Jin
    • Animal cells and systems
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    • 제10권4호
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    • pp.183-189
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    • 2006
  • The fine structural characteristics of the antennal sensory organs of a female millipede, Orthomorphella pekuensis, were observed with field emission scanning electron microscopy. On the surface of the antenna, four basic types of sensory receptor with the function of either mechanical or olfactory reception are identified in this female millipede. Of these, chaetiform sensilla (CS) and trichoid sensilla (TS) are related to mechanical reception, and four large apical cone sensilla (AS) and three subtypes of basiconic sensilla ($BS_1,\;BS_2,\;BS_3$) are likely to function in olfactory reception, as these receptors have porous structure commonly. Although this millipede also possess a number of primary or secondary sexual characters to improve the efficiency of reproduction, we could not observe their prominent sexually dimorphic characters in the antennal sensilla with the exception of minor structural and numerical differences.

변형된 유전자 알고리즘을 이용한 Multiple Array Antenna의 Beam 제어방식 (Beam Control of Multiple Array Antenna Using The Modified Genetic Algorithm)

  • 현교환;정경권;엄기환
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2006년도 하계종합학술대회
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    • pp.921-922
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    • 2006
  • This paper presents a novel scheme that quickly searches for the sweet spot of multiple array antennas, and locks on to it for high-speed millimeter wavelength transmissions. The proposed method utilizes a modified genetic algorithm, which selects a superior initial group through preprocessing in order to solve the local solution in a genetic algorithm. TDD (Time Division Duplex) is utilized as the transfer method and data controller for the antenna. Once the initial communication is completed for the specific number of individuals, no longer antenna's data will be transmitted until each station processes GA in order to produce the next generation. After reproduction, individuals of the next generation become the data, and communication between each station is made again. Simulation results confirmed the efficiency of the proposed method.

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스키마 공진화 알고리즘과 GA의 성능 비교 (A Performance Comparison between GA and Schema Co-Evolutionary Algorithm)

  • 전호병;전효병;심귀보
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2000년도 춘계학술대회 학술발표 논문집
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    • pp.134-137
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    • 2000
  • Genetic algorithms(GAs) have been widely used as a method to solve optimization problems. This is because GAs have simple and elegant tools with reproduction, crossover, and mutation to rapidly discover good solutions for difficult high-dimensional problems. They, however, do not guarantee the convergence of global optima in GA-hard problems such as deceptive problems. Therefore we proposed a Schema Co-Evolutionary Algorithm(SCEA) and derived extended schema 76988theorem from it. Using co-evolution between the first population made up of the candidates of solution and the second population consisting of a set of schemata, the SCEA works better and converges on global optima more rapidly than GAs. In this paper, we show advantages and efficiency of the SCEA by applying it to some problems.

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건축물 유지관리 효율성 향상을 위한 BIM 기반 정보관리 모델제시 (Development of BIM-based Information Management Model for Efficient Building Maintenance)

  • 성민우;김가람;유정호
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2011년도 춘계 학술논문 발표대회 1부
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    • pp.137-140
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    • 2011
  • A systemic building maintenance management is necessary to supply an convenience and safety environment by maintain the origin features for a building's life. However, the exist maintenance management system has some problems such as interoperability of information or standardization of data. In those reasons, a critical information for maintenance a building may be lost and changed. In addition, the data could be crashed or lost on a process of re-input or re-produce. This paper purpose the interoperability in exchanging data between design/construction and operation phases. In addition, this model will enhance the efficiency of building maintenance tasks through information quality improvement and data reproduction prevention.

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