• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6535-6539
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• 2015

This study was designed to assess, whether a new chemotherapeutic microtubule inhibitor, Epothilone B (EpoB, Patupilone), can induce DNA damage in normal ovarian cells (MM14.Ov), and to evaluate if such damage could be repaired. The changes were compared with the effect of paclitaxel (PTX) commonly employed in the clinic. The alkaline comet assay technique and TUNEL assay were used. The kinetics of DNA damage formation and the level of apoptotic cells were determined after treatment with IC50 concentrations of EpoB and PTX. It was observed that PTX generated significantly higher apoptotic and genotoxic changes than EpoB. The peak was observed after 48 h of treatment when the DNA damage had a maximal level. The DNA damage induced by both tested drugs was almost completely repaired. As EpoB in normal cells causes less damage to DNA it might be a promising anticancer drug with potential for the treatment of ovarian tumors.

• The Journal of the Acoustical Society of Korea
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• v.16 no.1E
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• pp.9-14
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• 1997

Check valves used in industrial and Nuclear Power Plant safety systems are susceptible to failure modes generally associated with wear of internal parts. Specifically, hinge pins, disc studs, pistons, and other mechanical parts may degrade over time, and in some cases, may which might produce a disabling event leading to plant or process shutdown. The primary diagnostic technique in the past has been to disassemble the valves. This procedure is costly, time consuming, and in the nuclear industry, it can lead to radiation exposure in some situations. Additionally repair and reassembly of a valve does not ensure proper operation. Non-intrusive diagnostic technologies including acoustics and magnetics with a digital signal analysis allow to evaluate check valve performance without a disassembly and is able to help the user detect degraded valve conditions.

• Journal of National Security and Military Science
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• s.13
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• pp.659-685
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• 2016

At this research, author discusses about ROK Army military supplies distribution system and suggests a direction of development as follows in order to achieve maximum efficiency. First, Develope a scientific technique to estimate quantity of repair part for futher demanding at the budgetting and procurement planning stage. Second, Introduce an Logistic Revolving Fund in other to reduce the procurement lead time & assure flexible procurement all year round. Third, Reestabilish supply step stages and reduce stock level which is authorized stock amount in logistic support unit. Fourth, Estabilish civilian - military integrated military supplies distribution system to improve the efficiency of logistics.

• Journal of Chest Surgery
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• v.28 no.2
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• pp.177-179
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• 1995

Sinus venosus type atrial septal defect is commonly associated with partial anomalous pulmonary venous return[PAPVR . Ideal surgical repair of sinus venosus ASD with PAPVR demands complete closure of septal defect with redirection of the anomalous pulmonary venous return to the left atrium without obstructing the superior vena cava[SVC or the anomalous pulmonary vein and without injury of sinoatrial node and residual shunt. In our two patients, the closure of sinus venosus ASD and correction of PAPVR could be accomplished by simple direct sutures without using a patch or flap. Both patients had a good outcome.

• Proceedings of the Korea Concrete Institute Conference
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• 1996.04a
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• pp.328-333
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• 1996

Concrete can be defective for several reasons, including an inadequate design, material selection of workmanship, failure to appreciate the hazards associated with prevailing enviromental conditions. Concrete can also deteriorate or be damaged in use. Thus, it is necessary to evaluate the safety of existing concrete strucutres. On the basis of these reasons, they must be performed for repair or rehabilitation. Presently, strengthening methods of R/C structure used in Korea, are an enlargement of concrete member, strengthening with steel plate or CFRP on the R/C structure. It has been widely estabilished that strengthening effect of CFRP is superior to steel plate in terms of it's lighter unit weight and higher tensile strength. But there are no construction results of CFRP on the civil R/C structure in Korea. The strengthening design technique with CFRP, it's const겨ction, and it's strengthening effect for deteriorated R/C rahmen bridge is introduced in this paper.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.43 no.6
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• pp.423-426
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• 2017

Congenital auricular deformities may be either deformational or malformational. Malformational anomalies present with a skin or cartilage shortage. Two cases with congenital cleft earlobe were presented. A new surgical technique using a two-layered repair with front and back flaps were introduced. She waited to begin wearing earrings until six months after the surgery to prevent possible scar contracture. The patients were followed up for a period ranging from 3 to 14 months. The earlobe volume deficiency was replaced, and acceptable scar maturation was obtained.

• Journal of Korean Foot and Ankle Society
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• v.15 no.4
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• pp.243-246
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• 2011

Lisfranc injury is complex and difficult to treat. Making the correct diagnosis and achieving an anatomical reduction are important factors in regard to achieving a favorable outcome with this injury. We describe a new technique that we have found to be useful for stabilizing Lisfranc injury. This method is relatively fast and simple, and it provides non-rigid fixation. Also, it eliminates the need for implant removal. To date, we have achieved predictable results for stabilizing and treating this injury with the use of a $TightRope^{TM}$ Device, instead of traditional interfragmental screw fixation. In this report, we describe a case in which this method was used with satisfactory short-term results.

• Journal of Korean Foot and Ankle Society
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• v.15 no.2
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• pp.107-109
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• 2011

We report here on a case of Achilles tendon rupture associated with ipsilateral bimalleolar fracture that was caused by ski injury. The association of an ankle fracture with rupture of the Achilles tendon is even more infrequent, although both injuries alone are extremely common. We treated as a operation of Achilles tendon repair with Krackow method and open reduction with Tension-band wiring technique for bimalleolar fracture.

• Journal of Korean Orthopaedic Sports Medicine
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• v.6 no.2
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• pp.88-91
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• 2007

Persistent instability following an acute lateral ankle sprain eventually require ligamentous reconstruction in some cases. Over 50 surgical procedures have been described to reestablish lateral ankle stability varying from direct in situ repair of the anterior talofibular ligament and the calcaneofibular ligament to augmented reconstructions with either autograft or allograft tissue. The author describes the rationale and the technique of anatomic ankle ligament reconstruction with the 4th extensor digitorum longus tendon.

• Journal of Chest Surgery
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• v.33 no.9
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• pp.756-760
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• 2000

Traumatic aortic transection after blunt chest injury is highly lethal and has high operative mortality. Recently, the diagnostic and therapeutic method of this injury is advanced, especially in spinal cord protection during aortic cross-clamping. We have experienced two cases of traumatic aortic transection with left hemothorax after blunt chest injury, which was diagnosed in operative field. The transected aorta was primarily repaired with clamp and sew method and postoperative paraplegia had not occured. The patients were dischraged without any significant complications. We report these cases with a review of literature.