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The Effect of MgO Content on the Preparation of Porous Hydroxyapaite Scaffolds by Polymer Sponge Method (폴리머 스펀지법을 이용한 다공성 수산화아파타이트 지지체 제조 시 MgO 첨가량에 따른 영향)

  • Jin, Hyeong-Ho;Min, Sang-Ho;Lee, Won-Ki;Park, Hong-Chae;Yoon, Seog-Young
    • Korean Journal of Materials Research
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    • v.16 no.11
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    • pp.715-718
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    • 2006
  • Porous hydroxyapatite (HAp) scaffolds have been prepared by using the slurry including HAp and magnesia based on the replication of polymer sponge substrate. The influence of MgO content in slurry on the pore morphology and size, density, porosity, and mechanical strength of porous HAp scaffolds was investigated. The obtained scaffolds with average pore sizes ranging 150 to 300 mm had open, relatively uniform, and interconnected porous structure regardless of MgO content. As the MgO content increased, the pore network frame of scaffolds became to be relatively stronger, even though the pore size was not much changed. The compressive strength of the scaffolds increased rapidly with the increase of MgO content because of increasing the pore wall thickness and density of the scaffolds. As a result, the porosity, density, and compressive strength of the porous HAp scaffolds prepared by the sponge method were significantly affected by the addition of MgO.

Investigation into shear properties of medium strength reinforced concrete beams

  • Shah, Attaullah;Ahmad, Saeed;Khan, Salimullah
    • Structural Engineering and Mechanics
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    • v.35 no.3
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    • pp.265-282
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    • 2010
  • The shear contribution of transverse steel in reinforced concrete beams is generally assumed as independent of the concrete strength by most of the building codes. The shear strength of RC beams with web reinforcement is worked out by adding the individual contributions of concrete and stirrups. In this research 70 beams of medium strength concrete in the range of 52-54 MPa, compressive strength were tested in two sets of 35 beams each. In one set of 35 beams no web reinforcement was used, whereas in second set of 35 beams web reinforcement was used to check the contribution of stirrups. The values have also been compared with the provisions of ACI, Eurocode and Japanese Code building codes. The results of two sets of beams, when compared mutually and provisions of the building codes, showed that the shear strength of beams has been increased with the addition of stirrups for all the beams, but the increase is non uniform and irregular. The comparison of observed values with the provisions of selected codes has shown that EC-02 is relatively less conservative for low values of longitudinal steel, whereas ACI-318 overestimates the shear strength of RC beams at higher values of longitudinal steel. The Japanese code of JSCE has given relatively good results for the beams studied.

Effects of different day length and wind conditions to the seedling growth performance of Phragmites australis

  • Hong, Mun Gi;Nam, Bo Eun;Kim, Jae Geun
    • Journal of Ecology and Environment
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    • v.45 no.2
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    • pp.78-87
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    • 2021
  • Background: To understand shade and wind effects on seedling traits of common reed (Phragmites australis), we conducted a mesocosm experiment manipulating day length (10 h daytime a day as open canopy conditions or 6 h daytime a day as partially closed canopy conditions) and wind speed (0 m/s as windless conditions or 4 m/s as windy conditions). Results: Most values of functional traits of leaf blades, culms, and biomass production of P. australis were higher under long day length. In particular, we found sole positive effects of long day length in several functional traits such as internode and leaf blade lengths and the values of above-ground dry weight (DW), rhizome DW, and total DW. Wind-induced effects on functional traits were different depending on functional traits. Wind contributed to relatively low values of chlorophyll contents, angles between leaf blades, mean culm height, and maximum culm height. In contrast, wind contributed to relatively high values of culm density and below-ground DW. Conclusions: Although wind appeared to inhibit the vertical growth of P. australis through physiological and morphological changes in leaf blades, it seemed that P. australis might compensate the inhibited vertical growth with increased horizontal growth such as more numerous culms, indicating a highly adaptive characteristic of P. australis in terms of phenotypic plasticity under windy environments.

A PHOTOELASTIC STUDY OF THE STRESS DISTRIBUTION IN THE ALVEOLAR BONE BY VARIOUS MOLAR UPRIGHTING SPRINGS (Molar Uprighting Spring에 의해 발생되는 치조골내의 응력분포에 관한 광탄성학적 연구)

  • Choi, Jin-Hugh;Kim, Jong-Chul
    • The korean journal of orthodontics
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    • v.21 no.2 s.34
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    • pp.353-366
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    • 1991
  • This study was performed to analyze the effects of forces to the alveolar bone by various molar uprighting spring such as helical uprighting spring. T-loop spring, Modified T-loop spring and open coil spring. The simplified two-dimensional photoelastic model was constructed with a lower left posterior quadrant containing the second molar, the first and second premolars and the canine, with the first molar missing. Several molar uprighting springs were fabricated from 0.017 by 0.022 inch blue Elgiloy and applied to the photoelastic model. Two-dimensional photoelastic stress analysis was performed, and the stress distribution was recorded by photography The results obtained were as follows; 1. In all the kinds of the springs, the center of rotation of the mandibular second molar was oserved at the apical 1/5-1/6 between the alveolar crest and the root apex. 2. In all the kinds of the spring, the stress induced in the mesial root surface of the mandibular second molar was relatively homogeneous but there was some difference in the magnitude of the stress. 3. In the kinds of the springs, the distal crown tipping moment of the second molar was increased in turn as open coil spring, helical uprighting spring, T-loop spring, and modified T-loop spring. 4. The largest extrusive force was occured in the T-loop spring, intrusive force was occured in Modified T-loop spring only, and the largest distal tipping force was occured in open coil spring. 5. In the T-loop spring with activation, the stress induced in the mesial root surface of the second molar was increased gradually from the root apex to the alveolar crest and highly concentrated in the alveolar crest.

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Fabrication and Performance of $Bi_{0.5}Sb_{1.5}Te_{3}/Bi_{2}Te_{2.4}Se_{0.6}$ Thin Film Thermoelectric Generators ($Bi_{0.5}Sb_{1.5}Te_{3}/Bi_{2}Te_{2.4}Se_{0.6}$계 박막형 열전발전 소자의 제작과 작동 특성)

  • Kim Il-Ho;Jang Kyung-Wook
    • Journal of the Korean Vacuum Society
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    • v.15 no.2
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    • pp.180-185
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    • 2006
  • Microwatt power level at relatively high voltage(order of volt) was produced by $Bi_{0.5}Sb_{1.5}Te_{3}/Bi_{2}Te_{2.4}Se_{0.6}$ thin film thermoelectric generators, and maximum output power varied with temperature difference in the square-law relation. Output voltage and current were possible to control by changing the way of electrical connection as well as the number of stacking plate-modules. Variation of open circuit voltage and short circuit current with temperature difference showed a linear relationship. There were, however, some differences in variations; open circuit voltage were dependent on the number of plate-module when connected in series, but it was not for parallel connection. On the other hand, short circuit current showed the opposite behavior to the case of open circuit current.

Open Lung Biopsy for Diffuse Infiltrative Lung Disease (미만성 폐질환에 대한 개흉적 폐생검)

  • 김남혁
    • Journal of Chest Surgery
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    • v.28 no.11
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    • pp.1014-1018
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    • 1995
  • To confirm diagnosis and to set proper therapeutic strategy, open lung biopsies were done in 57 patients who were suspected for diffuse interstitial lung disease from January 1985 to December 1994. Among them, 35 were male and 22 were female[M:F=l.6: 1 and mean age of the patients is 53.5$\pm$ 2.3[24-81 years. Tissue for histologic studies were obtained from left lung in 33, from right lung in 24according to the distributions of the pathology. Preoperative diagnostic work-up`s were chest X-ray, CT[HRCT scan, sputum study, bronchoscopy[BAL, TBLB and PTNA and all of them were unsuccessful to confirm diagnosis. In comparison of pulmonary function tests between preoperative and postoperative values, there were no significant differences in FVC, FEV1, FEV1/FVC[p 0.05 but in AaDO2[p[0.05 . Postoperative complications including atelectasis, wound infection, pulmonary edema and respiratory insnfficiency, were shown in 5 cases[8.8% , and two of them were died of respiratory failure and sepsis[mortality rate 3.5% . Pathologic diagnosis was confirmed in 53 cases postoperatively but it was undetermined in 4[diagnostic yield rate 93.0% . In comparison between preoperative clinical diagnosis and postoperative pathologic diagnosis, new diagnosis were made in 17 cases[29.8% and preoperative tentative diagnosis were confirmed histologically in 36 cases[63.2% . In 4 cases[7.0% , however, diagnoses were not confirmed after biopsies. Therapeutic plans were reset in 46 cases[80.7% in accordance with the final diagnosis.In conclusion, open lung biopsy is recommended for a specific diagnosis and proper therapeutic plan in diffuse interstitial lung diseases because of its high diagnostic yield Irate and it`s relatively low morbidity and mortality rate in these tompromised patents.

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Continuous Antiemetic Effects of Single Intravenous Injection of Antiemetics during Postoperative Pain Control with Morphine (Morphine 정주를 이용한 술후 통증 조절시 진토제 일회 정주의 지속적 항오심 및 항구토 효과)

  • Choi, Gi-Sun;An, Chi-Hong;Park, Sung-Sik;Lim, Dong-Geon;Baek, Woon-Yi;Park, Jin-Woong
    • The Korean Journal of Pain
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    • v.10 no.1
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    • pp.42-47
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    • 1997
  • Background : This study was designed to evaluate the continuous effects of single intravenous injection of antiemetics on nausea and vomiting during continuous morphine injection for postoperative pain control. Methods : Prior to the study, we divided patients into two major groups according to the type of surgery performed intra-abdominal(Open: O) and non intra-abdominal(Close: C). When patients regained orientation after routine general anesthesia, enflurane-$O_2-N_2O$, we injected bolus dose of morphine and started continuous injection of morphine for postoperative pain control(Group I; Control). After bolus injection and just before continuous injection, we injected single dose of droperidol(Group II) or ondansetron(Group III). Mean arterial blood pressure, heart rate, pain score and symptom-therapy score were checked at 10 minutes, 4, 8, 16, 24, 36 hours after continuous morphine injection. Results : The pain score of group III was lower than group II(10 min.) and group I(24, 36 hours) in the open group. Symptom-therapy score of group III(10 min., 4, 24 hours) and group II(10 min.) were lower than group I in the open group. In the close group, symptom-therapy score of group III(8 hours) was lower than group I. Conclusions : Single intravenous injection of antiemetics have a tendency of lowering symptom-therapy score for 36 hours in spite of their relatively short elimination half-life.

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Synthesis of Zeolite from Sewage Sludge Incinerator Fly Ash by Hydrothermal Reaction in Open System (Open System 수열반응을 통한 하수슬러지 소각 비산재의 Zeolite 합성가능성)

  • Lee, Je-Seung;Eom, Seok-Won;Choi, Han-Young
    • Journal of Environmental Health Sciences
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    • v.33 no.4
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    • pp.317-324
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    • 2007
  • The sewage treatment sludge disposal has become a serious environmental problem because of restricted direct land-filling and oceandumping in spite of their large amounts discharged. So the recycling of sewage treatment sludge is very useful alternative for waste management. Here, we studied the feasibility of zeolite synthesis in open system from the sewage treatment sludge incinerator fly ash by means of hydrothermal synthesis. We considered the concentration of NaOH, reaction time, reaction temperature and reaction step as synthesis variables. The phase of zeolite products was identified by X-ray diffractometer(XRD) and ammonium ion exchange test was performed for the raw fly ash and two zeolite products(Z-3 and Z-5). In leaching test of the raw fly ash, hazard metal is detected very low level compared with regulatory leaching test standard. But in total recoverable test, the total contents of the fly ash were very high in terms of the standard for waste-derived fertilizer. Through hydrothermal reaction, small amount of zeolite P was synthesied in 1 N of NaOH solution and relatively large amount of hydroxysodalite was synthesied in 3 N and 5 N of NaOH solution with similar peak intensity. Addition of an aging step in the synthesis didn't increase the amount of zeolite phase. Maximum $NE_4^+-N$ exchange capacity is 1.49 mg $NH_4^+-N/g$ in Z-3 and 1.38 mg $NH_4^+-N/g$ in Z-5. Most of the ammonium ion is exchanged in 30 minutes and disorption did not occur until 5 hours.

A Technique for Assist in Positioning the Proximal Segment during Open Reduction of a Fractured Mandibular Condyle (하악 과두 골절의 개방 정복 시 근위 골편의 수복법)

  • Kim, Myung Good
    • Archives of Plastic Surgery
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    • v.33 no.6
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    • pp.792-796
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    • 2006
  • Purpose: After exposure of fracture site, the proximal segment must be reduced to their preinjury position for open reduction of fractured mandibular condyle. We examined the use of inter-maxillary fixation screws or titanium screws tied with stainless steel wire to assist in positioning of proximal segment. Since it enables to make a relatively small preauricular incision by not disturbing the operative field like Moule pin, we can reduce the danger of injury to the facial nerve. Methods: A preauricular approach was used for exposure, reduction, and rigid fixation in 4 cases of mandibular condylar fractures. Inter-maxillary fixation screws or titanium screws tied with stainless steel wire were used to assist in aligning proximal segment. The joints were submitted to functional exercises and postoperative radiologic and clinical follow-ups were performed. Results: No facial nerve lesions were found in all 4 cases. Radiologic follow-up showed correct reduction and fixation in all 4 cases. Clinical follow-up showed an initial limitation, but normal morbility of the condyle was achieved within 4 months after the operation, with a maximum mouth opening of $34.1{\pm}5.2mm$ after 12 months. There found no occlusal disturbances, no trismus, no lateral deviations of the mandible. Conclusion: By using Inter-maxillary fixation screws tied with stainless steel wire, it was shown that reducing the proximal segment to their preinjury position is easy to perform and it enables us to make a minimal dissection below preauricular skin incision to avoid facial nerve injury.

Acepromazine inhibits hERG potassium ion channels expressed in human embryonic kidney 293 cells

  • Joo, Young Shin;Lee, Hong Joon;Choi, Jin-Sung;Sung, Ki-Wug
    • The Korean Journal of Physiology and Pharmacology
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    • v.21 no.1
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    • pp.75-82
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    • 2017
  • The effects of acepromazine on human ether-$\grave{a}$-go-go-related gene (hERG) potassium channels were investigated using whole-cell voltage-clamp technique in human embryonic kidney (HEK293) cells transfected with hERG. The hERG currents were recorded with or without acepromazine, and the steady-state and peak tail currents were analyzed for the evaluating the drug effects. Acepromazine inhibited the hERG currents in a concentration-dependent manner with an $IC_{50}$ value of $1.5{\mu}M$ and Hill coefficient of 1.1. Acepromazine blocked hERG currents in a voltage-dependent manner between -40 and +10 mV. Before and after application of acepromazine, the half activation potentials of hERG currents changed to hyperpolarizing direction. Acepromazine blocked both the steady-state hERG currents by depolarizing pulse and the peak tail currents by repolarizing pulse; however, the extent of blocking by acepromazine in the repolarizing pulse was more profound than that in the depolarizing pulse, indicating that acepromazine has a high affinity for the open state of the channels, with a relatively lower affinity for the closed state of hERG channels. A fast application of acepromazine during the tail currents inhibited the open state of hERG channels in a concentration-dependent. The steady-state inactivation of hERG currents shifted to the hyperpolarized direction by acepromazine. These results suggest that acepromazine inhibits the hERG channels probably by an open- and inactivated-channel blocking mechanism. Regarding to the fact that the hERG channels are the potential target of drug-induced long QT syndrome, our results suggest that acepromazine can possibly induce a cardiac arrhythmia through the inhibition of hERG channels.