• Korean Journal of Community Nutrition
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• v.6 no.2
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• pp.121-129
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• 2001

The purpose of this study was to estimate the prevalence and to identify risk factors of overweight among preschool children in Korea. The study subjects were 750 children, aged 2-6, attending child care centers in Korea. A measurement of the height and weight of the children, as well as collection of wide range of variables including general characteristics, and potential factors related with dietary habit for children and their parents, were conducted. Overweight was defined based on more than 110% of ideal body weight. A logistic regression analysis was adopted to identify the factors associated with overweight. Subjects were classified into three categories according to the obesity index : underweight(PIBW〈90%, n=34), normal(90%$\leq$PIBW〈110%, n=577), and overweight(PIBW$\geq$110%, n=139). The overall prevalence of overweight and underweight of the subjects were 21.3% and 4.0% of the boys and 15.5% and 5.1% of the girls respectively. Parent's obesity was associated with a higher risk of overweight on girls. Subjects o the third quartile(girls) and fourth quartile(boys) of income level had a substantially higher risk of overweight than did those in the first quartile. Fast eating, overeating, and food prejudice were also associated with an increased risk of overweight. The results of a logistic regression analysis showed that the eating habits and food preferences of the children were the most influencial factors on overweight. These finding may imply the importance of early stage nutrition education on rational dietary habit to prevent prevailing obesity of preschool in Korea.

• The Journal of Internal Korean Medicine
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• v.45 no.4
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• pp.700-709
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• 2024

This retrospective, multicenter, observational study aimed to evaluate the effects of herbal medicine treatment on liver function in obese patients exhibiting elevated liver enzymes. Conducted from May 2023 to April 2024 at various Korean medicine clinics, the study included 84 patients who underwent herbal treatments for obesity. All participants had at least one liver function test (LFT) showing elevated levels of aspartic amino transferase (AST), alanine amino transferase (ALT), or gamma glutamyl transferase (GGT), and a subsequent LFT performed after a minimum of 90 days. The study excluded patients with potential confounding factors such as hepatitis, antibiotic usage, or recent surgeries. The study showed significant reductions in AST, ALT, and GGT levels, with AST and ALT improving to within the normal range and GGT approaching normal levels. Patients also experienced statistically significant reductions in weight and BMI, meeting the minimum clinically important difference threshold. These findings suggest that herbal treatments for obesity are not only safe for patients with obesity-related liver enzyme abnormalities but also effective in improving liver function. This study shows that herbal treatment is effective in the management of obesity-related liver disease and confirms the safety and efficacy of an obesity treatment herbal formula containing ephedra. Larger prospective studies are needed to confirm these findings.

• Korean Journal of Adult Nursing
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• v.21 no.3
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• pp.281-292
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• 2009

Purpose: The purpose of this study was to investigate the risk factors related to prehypertension in Korean adults. Methods: The data were obtained from the Korean National Health and Nutrition Examination Survey 2005. The subjects of this study were 3,981 adults aged over 20 years of age. Demographic characteristics, alcohol drinking, smoking, physical activity, stress, BMI, serum lipid profiles and blood pressure were analyzed in this study. Results: Prevalence of prehypertension was 38.9% in this study. As the result of multiple logistic regression, the risk of prehypertension in male, elderly and low income persons was increased. And the risk of prehypertension was increased in the case of problem drinking, alcohol abuse, formal smoker, overweight, obesity and hyperlipidemia in triglyceride. Conclusion: To decrease prehypertension prevalence, it is necessary to detect and manage the influencing risk factors of prehypertension such as alcohol drinking, smoking, obesity, physical activity, stress and serum lipid profiles.

• Korean Journal of Health Education and Promotion
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• v.32 no.2
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• pp.65-74
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• 2015

Objectives: The purpose of this study was to examine factors that influencing medication adherence in patients with dyslipidemia. Methods: Data were collected from fifth Korean National Health and Nutrition Examination Survey (2010-2012), we selected 1,992 adults aged over 30yr who participants in both health examination and health interview survey. Using the SAS 9.2 Program, data were analyzed using ${\chi}^2$-test, t-test and multiple logistic regression. Results: Medication adherence was associated with age, obesity, educational level and Health screening within 2 years. The cases with older age, obesity, higher level of education and experience of Health screening within 2 years showed significantly high medication adherence, whereas high risk group of dyslipidemia such as cardiovascular disease patients showed low medication adherence. Conclusions: Further study and strategies are needed to improve high levels of medication adherence based on factors influencing such as age, obesity, level of education and health screening experience within 2 years.

• Journal of Ginseng Research
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• v.48 no.1
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• pp.12-19
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• 2024

Skeletal muscle (SM) is the largest organ of the body and is largely responsible for the metabolism required to maintain body functions. Furthermore, the maintenance of SM is dependent on the activation of muscle satellite (stem) cells (MSCs) and the subsequent proliferation and fusion of differentiating myoblasts into mature myofibers (myogenesis). Natural compounds are being used as therapeutic options to promote SM regeneration during aging, muscle atrophy, sarcopenia, cachexia, or obesity. In particular, ginseng-derived compounds have been utilized in these contexts, though ginsenoside Rg1 is mostly used for SM mass management. These compounds primarily function by activating the Akt/mTOR signaling pathway, upregulating myogenin and MyoD to induce muscle hypertrophy, downregulating atrophic factors (atrogin1, muscle ring-finger protein-1, myostatin, and mitochondrial reactive oxygen species production), and suppressing the expressions of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in cachexia. Ginsenoside compounds are also used for obesity management, and their anti-obesity effects are attributed to peroxisome proliferator activated receptor gamma (PPARγ) inhibition, AMPK activation, glucose transporter type 4 (GLUT4) translocation, and increased phosphorylations of insulin resistance (IR), insulin receptor substrate-1 (IRS-1), and Akt. This review was undertaken to provide an overview of the use of ginseng-related compounds for the management of SM-related disorders.

• Journal of Nutrition and Health
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• v.20 no.4
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• pp.272-280
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• 1987

This research is intended to reveal the correlations between diabetes and dietary and other related factors. We were studied for 257 diabetics, in t도 9 general hospitals, located at Seoul, From August 109 to September 3, 1986. The result of this study can be follow ; 1) Distribution of the subjects according to their general characteristics ; The sex ration of the subjects is 1.06 ; 1.00 (male ; female), and the average age is 54.7 $\pm$10.9 years. Among the subjects 28.8% have a family history of diabetes ; the closer the genetic relationship, the more hereditory factors play a part. 2) Distribution of the scores according to their socioeconomic status ; As the socioeconomic status goes p, the intake of calories and fiber increases ; however, the frequency of eating out and the degree of physical activity decrease. 3) Relationship between obesity prevalence and each variable ; Among the subjects 27.2% are obese, and 60.3% have been obese in the past. Even though there is no significant relationship between the food habit and obesity, the number of people who are obese shows a significant increase as the socioeconomic status improves. 4) The effect of sex on each variable ; The intake of calories, sugar, alcohol and coffee is higher in male subjects, as is the frequency of eating out. In regular exercise and physical activity, there are significant differences between male and female subjects.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.8
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• pp.84-93
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• 2016

This study was conducted to determine family factors related to obesity of high school students. A descriptive correlational study was conducted with 384 high school students in I metropolitan city. Data were collected from February to April of 2015 using self-report structured questionnaires. Questionnaires included weight, height, individual characteristics of subjects and their familial characteristics. Collected data were analyzed by multiple logistic regression. Logistic regression analysis revealed that male gender (aOR = 4.37; 95% CI [1.26, 15.16]), having a non-regular paternal job (aOR = 3.10; 95% CI [1.15, 8.40]), and not being in a two parent family (aOR = 3.52; 95% CI [1.29, 9.61]) were statistically significant contributors to obesity. These results indicate that it is necessary to improve social awareness regarding the obesity risk of male adolescents. Health care providers should recognize the importance of family factors such as parental socioeconomic status and family structures.

• Journal of Community Nutrition
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• v.6 no.3
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• pp.155-163
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• 2004

In our country, cardiovascular disease (CVD) and Coronary heart diseases (CHD) are the leading causes of death. It is well known that CHD is multifactorial, involving environmental factors such as diet, level of exercise and cigarette smoking, and inherited factors. According to the statistical data in 2003, the cause of death with the highest mortality was including hypertension, ischemic heart disease and atherosclerosis, which accounted for $24.7\%$ of total mortality. In spite of, there have been few study reports on the change of biochemical markers and mechanisms concerned. The development of biochemical markers is required for an early diagnosis and treatment of cardiovascular diseases that are related with dietary habits of Korean people enjoying mixtures of traditional dietary style and westernized food-styles. Therefore, the most efficient cost-saving biochemical marker was established in this study, through analysis of biochemical markers related with dietary habits which are susceptibly being changed in association to cardiovascular diseases from the pre-disease phase, and through reanalysis and assessment of early diagnosis of and preventive effects of diagnosis of cardiovascular diseases by demographical character including sex, age, and socioeconomic level with use of biochemical markers that are identified and selected among the parameters in consideration of the effectiveness and appropriateness of early diagnosis of diseases. The appropriateness of biochemical markers was reviewed by professionals (medical, pharmaceutical area and food/ nutrition area) and CRP(C-Reactive Protein) and was identified to be possible in Korea. It is thought that these biochemical markers may be used as the basic data for early diagnosis and prevention of cardiovascular diseases (CVD) which may be used for Korean people.

• Journal of Korean Medicine for Obesity Research
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• v.10 no.2
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• pp.27-39
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• 2010

Objectives This study was performed to figure out relations of self-esteem, anxiety and the other factors related with obesity in obese children. Methods Forty-two children(21 boys and 21 girls) those who were diagnosed obesity have been recruited. To assess psychological factors, Self-esteem inventory(SEI), Revised Children's Manifest Anxiety Scale(RCMAS), International Physical Activity Questionnaires(IPAQ), Korean Eating Attitudes Test(KEAT-26) and Children's Depression Inventory(CDI) were administered. Behavioral characteristics were also analyzed. Results Self-esteem(SEI) had significant positive relationship with physical activity(IPAQ) and sleeping time. Self-esteem had significant negative relationship with anxiety(RCMAS), eating disorder(KEAT-26) and watching TV time. Anxiety had significant positive relationship with eating disorder(KEAT-26) and watching TV time, and negative relationship with physical activity(IPAQ) and sleeping time. All of participants seemed to be having depressive tendency. Conclusion Self-esteem and anxiety were significantly related. And eating disorder, physical activity, sleeping time and watching tv also affected to the self-esteem and anxiety of obese children.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.497-505
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• 2012

To determine the effects of Banggihwanggi-tang(BGHGT) on obesity, the obesity-related factors[gastrin, calcitonin gene related peptide(CGRP), serotonin, ghrelin, obestatin, glucagon-like peptide-1(GLP-1), insulin, orexin, leptin] were investigated in the stomach, pancreas, brain of mice by immunohistochemical(IHC) methods for 4 weeks. The change of body weight was more reduced in BGHGT administered group than that of control group. The IHC density of the gastrin and CGRP positive cells on pylorus was higher in BGHGT administered group than that of control group. The number of ghrelin immunoreactive cells on stomach was lower in BGHGT administered group than that of control group. The IHC of GLP-1 positive cells did not observe in the stomach of BGHGT administered groups. The IHC density of GLP-1 in the pancreas was lower in BGHGT administered group than that of control group. The IHC density of insulin positive cells in the pancreas was lower in BGHGT administered group than that of control group. The IHC density of orexin positive neurons in the diencephalon was slightly higher in BGHGT administered group than that of control group. The IHC density of NPY and leptin positive neurons was slightly higher in BGHGT administered group than that of control group. The IHC density of serotonin positive neurons was higher in BGHGT administered group than that of control group. Therefore, we conclude that BGHGT activates appetite inhibitor through appetite related enteroendocrine cells and neuropeptides in stomach, pancreas and brain, and this activation may also be responsible for the inhibition of feeding behavior.