• 대한소아치과학회지
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• 제24권1호
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• pp.19-26
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• 1997

Odontodysplasia is a rare developmental anomaly of tooth formation in which hard tissue are affected. Odontodyplasia affects the primary and permanent dentitions in the maxilla, mandible, or both jaws. The maxilla is involved twice as often as the mandible. The condition is more common in female than in male patients and in the anterior than in the posterior regions. The clinical manifestation of odontodysplasia are hypoplasia and hypocalcification of the enamel and dentin of affected teeth. Teeth tend to be small and discolored, with short roots and widely open pulp canal. Delayed eruption of affected teeth with abscess formation is common. Radiographically teeth assume a faint radiolucent image ("ghost teeth"). enamel and dentin appear thin and are similar in radiodensity. The pulp chambers are often larger than normal, calcifications(pulp stone and denticle) are found within them. The etiology of regional odontodysplasia is unknown. However, several causes have been discussed, including somatic mutation, local circulatory disorders, local trauma, failure of migration and differentiation of neural crest cells, local infection.

• 대한두개안면성형외과학회지
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• 제11권1호
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• pp.58-61
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• 2010

Purpose: Sebaceous carcinoma is a rare malignant tumor that occurs mostly in head and neck regions. Early diagnosis and treatment are necessary because it tends to be locally aggressive and goes through distal metastasis with fast progression. This study presents reliable surgical methods for sebaceous carcinoma in head and neck regions. Methods: Three patients were included in this study. First, a 61-year-old woman visited the hospital with a yellow-colored, slowly growing mass on the left ala. A 54-year-old woman had a brown-colored mass on her right preauricle. Last case was a 62-year-old man who had a yellow-colored mass on his scalp. CT scan and punch biopsy were done. All cases were diagnosed as sebaceous carcinoma. The lesions were resected with 10 mm safety margin and various regional flaps were used for reconstruction. Results: Histological examination revealed sebaceous differentiation and local invasions. Postoperatively, all patients did not suffer from complication and no recurrence was found. Conclusion: We recommend early wide excision with an enough safety margin, and a regional flap as a treatment of sebaceous carcinoma.

• 한국작물학회지
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• 제44권3호
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• pp.256-262
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• 1999

To evaluate the genetic diversity and structure of the South Korean soybean population, 233 landraces collected in various regions of the country were surveyed for 15 allozyme loci and one protein locus. The South Korean population was fixed or nearly fixed at seven of the 16 loci tested. The number of alleles per locus was 2.06 and Nei’s gene diversity was 0.194. These values were lower than the values for the same 16 loci previously reported for the Japanese and Chinese populations. The differences among eight regional groups were not so marked, with only 7.2% of the total variation arising from regional differentiation. Three southern regional groups (Chollabuk-do, Chollanam-do and Kyong-sangnam-do) exhibited a relatively high variability because of frequent occurrence of alleles characteristic of the Japanese population. A marked difference was found in allelic frequencies at the Dial locus between large-seeded landraces and small-seeded ones, suggesting that the latter, which are used mainly for bean sprouts, had been established independently of the former, which are used mostly for soy sauce and cooking with rice. Not only the region but also the usage as food materials should therefore be taken into consideration in designing an efficient collection and preservation method for the Korean soybean landraces.

• The Journal of Asian Finance, Economics and Business
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• 제5권3호
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• pp.169-178
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• 2018

This study aims is to explore of the theoretical concepts of regional imbalances and spatial inequality, analysis of spatial distribution of economic growth and identifying of "growth poles" for sustainable development in the regions of Kazakhstan. Based on the theoretical views, we conclude that the key direction of regional policy is the search and development of "growth poles", which will distribute their potential equally to backward regions. The authors propose the methodological tools for presenting a standard form of evaluation of spatial distribution and inequality of the regions of Kazakhstan. This study confirms the importance of using of proposed methods and its application for objectively and realistically defines "growth poles" for sustainable development. Further, the obtained results showed the distribution of Kazakhstan's regions by economic growth and specialization with using modified index of KDI. According to the results of this theoretical and empirical study proved that distribution of the regions of Kazakhstan and results of KDI indexes shows that the spatial differentiation of economic development, but its level and dynamics are different in different respects. In addition, according to the conducted survey, we conclude that one of the most important tasks is sustainable growth based on "growth poles" for sustainable development.

• 한국주거학회논문집
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• 제12권2호
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• pp.65-76
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• 2001

The study background is that Mo-Jung happens as the produce of the agricultural society but it is not easy to find it beside Ho-nam area. Because of this, it results construction has. The study progress is to understand the happening time, and regional cause the Mo-Jung construction has. The study progress is to understand the happening time of Mo-Jung, constructional meaning, and the meaning of Mo-Jung with the investigation method of literature consideration of the village society, data of the existing study, survey investigation, interview, and question through the process of analyzing the characteristics of differentiation of the village and Dure organization. 1. Mo-Jung construction has the meaning of vernacular construction reflecting the meaning of village community intensively as an element comprising the village, and the territory of Mo-Jung space is revealed as the male space. 2. The economic wealth of the village community and the image reflecting the community sense are stood out. 3. It is the reason why Mo-Jung construction is limited to Ho-nam area and is explained as the life style difference each village community has, the regional characteristic difference Dae-dong play of Yong.Ho-nam areas have, etc. so to speak. 4. It is estimated that the happening time of Mo-Jung is after the 18th century when the agricultural As my suggestion, Mo-Jung construction is the construction phenomenon reflecting the phenomenon of social change directly and it is to suggest the possibility of approaching the regional housing construction as the life style difference the life community of each area has is reflected. production quantity was increased and Dure organization was activated.

• 한국실내디자인학회논문집
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• 제21권5호
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• pp.98-105
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• 2012

The purpose of this study is to present the direction for effective public environment design by becoming aware of the social, cultural and historical values that are inherent to the specific regions once again. Concept of regions' sense of identity, regions' resources and regionality were identified as a means based on the basic cityscape plan and guideline for public design. Sample city was analyzed by extracting the regionality elements, and the results are as follows. First, appropriateness of the direction for the public environment design based on the regional identity was confirmed. The need to establish regional identity in the cityscape plan is specified when it comes to the basic goal, strategy and direction. Second, public environment design should be planned within the context of the cityscape. It is necessary to improve with integrated plan by setting up the consistent goal, direction and detailed guideline based on the basic concept of cityscape plan. Third, 'design city' requires the development of the unique design and planned techniques based on the harmony with the existing resources. It is necessary to uncover the powerful design elements that are exclusive to specific regions, and to search for differentiation and visualization to form consensus. Public environment based on regional identity will improve if the above mentioned research results are used as the basic data when it comes to the implementation of public environment design.

• 대한한의진단학회지
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• 제18권2호
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• pp.121-136
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• 2014

Objectives For the excellent differentiation of syndromes, we study on the individual characteristic factor by the inspection of body shape. Methods To the subject of diagnosis special books and diagnostics textbook of korean medicine, we arrange the individual characteristic factor by the four methods of diagnosis. Results The individual characteristic factor analyzed by the inspection of the body shape in the "Huangdineijing 黃帝內經" and "Donguisusebowon 東醫壽世保元" was observed stereotyped. The inspection of the body shape means to diagnose the patient by examining the individual physical conditions of the patient. The body depends on visceral essence to nourish, while the functions of the viscera and the conditions of visceral essence may be reflected by the body. The inspection of individual physical strength and weakness may enable one to know the functions of the viscera and the conditions of ki(氣) and blood. And also the inspection of local regions is used to closely examine some regional areas to obtain necessary clinical data on the individual characteristic factor. Conclusion As the results, the individual characteristic factor by the inspection of body shape is very important item of the four methods of diagnosis(四診) and the differentiation of syndromes(辨證). And therefore the process on four methods of diagnosis and differentiation of syndromesis is necessary to divide the signs of individual characteristic factor and the signs of disease.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5301-5310
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• 2013

The biological mechanisms of cancer and associations with behavior of tumours need to be studied to understand progression and determine appropriate treatments. Here we investigated expression of VEGF, MMP-9 and E-cadherin in laryngeal SCCs and their relations with clinical behavior. This prospective study was based on 38 surgical specimens from patients with primary laryngeal SCC and data recorded in their cards. Expression of the three factors in tumor tissue was examined using immunohistochemistry and correlations with clinical parameters of primary tumors, regional lymph node metastases, stage of disease, histopathologic differentiation, and vascular/cartilage invasion were investigated. Regarding the cases with positive MMP-9 expression, the difference between well and moderately/poorly differentiated tumors was statistically significant. However, differences between early stage (stage I and II) and late-stage (stage III and IV) tumours, and between positive and negative for pLN metastasis were not. No significant relationship between positive VEGF and tumor differentiation or stage was apparent, but E-cadherin levels significantly differed between well and moderately/poorly differentiated tumours and with the presence of pLN metastasis. E-cadherin staining did not vary between MMP-9 positive and negative cases. In conclusion, MMP-9 may be a negative predictor of differentiation in laryngeal SCC, while E-cadherin is a predictor of differentiation and nodal metastases. Even if the difference between VEGF expression and tumor stage was not statistically significant, it seems that there exists some relationship, which might be clarified with a greater number of cases.

• 한국지역지리학회지
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• 제22권1호
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• pp.1-24
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• 2016

이 논문은 2000년대 이후 한국의 신지역지리학의 발달 배경 및 종합적 연구 동향에 관한 앞선 논문에 이어서, 인문지리학의 주요 전공분야들에서 이루어진 경험적 지역 연구의 동향과 과제를 고찰하고자 한다. 특히 장소와 경관에 관한 역사문화지리학, 산업지구(또는 클러스터)에 관한 경제지리학, 도시 네트워크와 분화에 관한 도시(사회)지리학에서 지역이 어떻게 연구되고 있는가를 살펴보았다. 각 전공분야들에서 연구자들은 지역을 지칭하기 위해 각기 다른 용어들을 사용하고 있지만, 지역의 특수성을 보편적 과정과 관련시키고, 본질적 실체이지만 또한 담론적 구성물로 이 해하며, 영역성보다는 네트워크나 관계성에 더 많은 관심을 두고 있음이 확인된다. 이러한 공통점들은 기존의 전통적 지역연구에서 벗어나 신지역지리학의 경향을 반영한 것으로 평가된다. 앞으로 지역 연구에서 지역의 개념화를 위한 주요 과제로, 특수성/보편성, 실체성/구성물, 그리고 영역성/관계성의 이분법을 극복할 필요가 있으며, 또한 지역에 관한 경험적 연구의 주요 이슈로 새로운 관점에서의 지역적 종합, 지역 내 외적 관계로서 지역불균등발전, 그리고 대안적 지역 만들기 등이 제시된다.

• 한국지역지리학회지
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• 제7권2호
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• pp.1-16
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• 2001

이 글의 목적은 독일이 당면하고 있는 실업문제와 그 구조적 특성을 살펴보고, 실업이 공간적으로 어떻게 전개되고 있으며 그 원인이 무엇인가를 논의하는데 있다. 독일은 1950년 말이래 안정된 고용체계를 확립하고 완전고용을 성취하였으나, 1970대 중반에 들어서면서 대량실업 사태에 직면하게 되었다. 특히 1990년대에 들어 통일과 함께 구 동독에서 실업률이 높아지면서 불안정한 노동시장이 구조화되고 있으며, 일부 인구집단이 고용체계로의 진입 및 퇴출 과정에서 선별작용을 현저히 겪고 있다. 독일의 실업은 공간적으로 독특한 발전패턴을 보여주고 있는데, 전통적인 남북격차에 동서격차가 겹치는 다중적 양상과 아울러 지리적 권역에 따른 차별적 상황이 부각되고 있다. 특히 전반적인 고실업은 노동시장상의 정책기조의 변화와 통일이라는 시대적 변혁이 맞물려 만성화 내지 장기화되고 있으며, 그 지역적 편차는 노동력 수급에 있어 불균등을 반영하고 있다.