• Title/Summary/Keyword: redundant

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A Mutation of cdc-25.1 Causes Defects in Germ Cells But Not in Somatic Tissues in C. elegans

  • Kim, Jiyoung;Lee, Ah-Reum;Kawasaki, Ichiro;Strome, Susan;Shim, Yhong-Hee
    • Molecules and Cells
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    • v.28 no.1
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    • pp.43-48
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    • 2009
  • By screening C. elegans mutants for severe defects in germline proliferation, we isolated a new loss-of-function allele of cdc-25.1, bn115. bn115 and another previously identified loss-of-function allele nr2036 do not exhibit noticeable cell division defects in the somatic tissues but have reduced numbers of germ cells and are sterile, indicating that cdc-25.1 functions predominantly in the germ line during postembryonic development, and that cdc-25.1 activity is probably not required in somatic lineages during larval development. We analyzed cell division of germ cells and somatic tissues in bn115 homozygotes with germline-specific anti-PGL-1 immunofluorescence and GFP transgenes that express in intestinal cells, in distal tip cells, and in gonadal sheath cells, respectively. We also analyzed the expression pattern of cdc-25.1 with conventional and quantitative RT-PCR. In the presence of three other family members of cdc-25.1 in C. elegans, defects are observed only in the germ line but not in the somatic tissues in cdc-25.1 single mutants, and cdc-25.1 is expressed predominantly, if not exclusively, in the germ line during postembryonic stages. Our findings indicate that the function of cdc-25.1 is unique in the germ line but likely redundant with other members in the soma.

A Study on the Network Adjustment Analysis for Planimetric Positioning (수평위치 결정을 위한 망조정 해석에 관한 연구)

  • 유복모;조기성;이현직;곽동옥
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.9 no.2
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    • pp.37-48
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    • 1991
  • In this study, conventional network adjustment and combined network adjustment methods for single network adjustment methods for single network and centric combination network were compared by the analysis of root mean square error and standard error ellipse of observed points. It can be concluded from this study that for conventional surveying methods, the accuracy is in theorder of trilateration, traverse and triangulation, and for the case of combined surveying method, the accuracy is in the order of multilateration surveying, combined traverse and combined triangulation-trilateration surveying. And when establishing new control points, the accuracy can be improved by increasing redundant observations of centric combination network instead of using the single network. Also, in case of combined traverse surveying by adding observable laterals, accuracy level of trilateration could be achieved, and it was found that traverse is effective for large areas where sighting is easy, and combined traverse surveying is effective for urban areas where sighting is difficult.

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An Experiment on Redundancy in Simple Span Two-Girder Bridge - Effects of Lateral Bracing (단경간 2-거더교의 여유도 평가 실험-수평브레이싱의 효과)

  • Park, Yong Myung;Joe, Woon Do Ji;Hwang, Min Oh;Lee, Dae Yong;Yoon, Tae Yang
    • Journal of Korean Society of Steel Construction
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    • v.19 no.3
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    • pp.271-280
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    • 2007
  • This paper presents the results of an experimental study to evaluate the redundancy in two plate-girder bridges, which are generally classified as non-redundant load path structures. The study was performed at a time when one of the two girders was damaged. The bottom lateral bracing was considered the experimental variable, and two 1/5-scale bridge specimens of simple span with and without a lateral bracing system were fabricated. Loading tests were first performed on the intact specimens without a cracked girder, within an elastic range. Thereafter, the ultimate loading tests were conducted on the damaged specimens with an induced crack at the center of a girder. The test results showed that the cross beams and the concrete deck redistributed some of the load to the uncracked girder, but the lateral bracing system played an important role in improving the redundancy during the damage and was also effective for load redistribution even when the bridge was intact.

A Study on the Fatigue Design of Joint Detail of Vertical Stiffener in Two-Girder Bridge (2거더교의 수직보강재 연결상세부의 피로설계에 관한 연구)

  • Kwon, Soon Cheol;Kyung, Kab Soo;Park, Jin Eun
    • Journal of Korean Society of Steel Construction
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    • v.21 no.1
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    • pp.93-103
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    • 2009
  • Two-girder bridge is composed of primary members such as deck slab and main girder, and secondary member such as cross beam, vertical and horizontal stiffeners etc,. Two-girder bridge is prescribed as a non-redundant load path structure in the ASSHTO and the Korean Highway Bridge Design Code. Such structure is that if one girder is damaged, problems of function and safety of the bridge are caused. From the reasons, fatigue cracks in two-girder bridge can affect safety of the bridge seriously. Therefore, in this paper, fatigue evaluation was performed at connection parts of vertical stiffener and web with radius of curvature of scallop of vertical stiffener and thickness of web as variables. Such joint is known as a detail which has high possibility of fatigue crack in the bridge. Based upon the analytical results, preferable joint detail in terms of fatigue and simple empirical formula for fatigue evaluation of the detail were suggested.

Quantitative analysis of gene expression pattern in aspergillus nidulans mycelia by sequencing of 3-directed cDNA clones

  • Park. Yoon-Dong;Lee, Dong-Whan;Lee, Seog-Jae;Kim, Jong-Hwa;Chae, Keon-Sang
    • Journal of Microbiology
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    • v.34 no.1
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    • pp.25-29
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    • 1996
  • Since sequencing of randomly selected cDNA clones has been known to be a powerful approach to obtain information on gene expression pattern in specific cells or tissues, we have analyzed a 3'-directed cDNA library of vegetative mycelia of A. nidulans by single-pass sequencing of hundreds of randomly selected clones. Sequencing of 292 cDNA clones yielded 209 gene signatures (GSs) probably representing highly or lesser expressed genes in the vegetative mycelia. Among the 209 GSs, 25 (79 cDNA clones) appeared more than once and 184 only once. One GS appeared at a highest frequency of 6 times, 2 GSs5 times, 4 GSs 4 times, a GSs 3 times and 16 GSs twice. About 6.6% GSs comprizing of 13 GSs showed alternative polyadenylation. Among 23 redundant GSs, three were common in both mycelia and sexual organs, and 22 were probably mycelia-specific. Out of 209 GSs, 36 were identified in GenBank showing of 70% or greater similaritis. Only six GSs were for A. nidulans genes, and 13 GSs were of DNA or genes encoding cytoplasmic or organellar proteins. This pattern is similar to those in the human HepG2 cell line and in human colonic mucosa, although very few genes for nuclear proteins and for protein synthesis were in A. nidulans.

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Analysis on the Dynamic Characteristics of a DDV Actuation System of a FBW Aircraft (FBW 항공기의 DDV 구동장치에 대한 운동특성 해석)

  • Nam, Yun-Su;Park, Hae-Gyun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.34 no.3
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    • pp.74-80
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    • 2006
  • This paper deals with the control and fault monitoring of a DDV hydraulic actuation system. A hydraulic servo system has a nonlinear dynamics of an orifice flow through a valve spool. A full nonlinear model for a DDV actuation system is driven, and linearized to a simple model which is convenient for a control loop and fault monitor design. A top level requirement on the performance and safety for the actuation system is introduced. A control system and fault monitoring structure which can meet these requirements are discussed. A simulation package for a DDV actuation system which has a triplex redundant structure is developed.

A Fault Monitor Design for the Driving Currents of a DDV Actuation System of a FBW Aircraft (FBW 항공기의 DDV 구동장치에 대한 구동전류 고장 모니터 설계)

  • Nam, Yun-Su;Park, Hae-Gyun;;Choe, Seop;Gwon, Jong-Gwang
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.34 no.3
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    • pp.81-86
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    • 2006
  • This paper deals with a driving current fault monitor design methodology for a DDV actuation system which has a dual hydraulic power supply system, and triplex electric control capability. A fault existing among these redundant channels should be detected accurately and removed timely, and the remaining channels are to be reconfigured in order to compensate the role of a removed faulty channel. An integrated analysis on the aerodynamics, flight control laws, and DDV actuation system is essential for the design of an actuation system fault monitor. A method to define a fault transient boundary which specifies a maximum travel of an actuation system caused by the first faulty operation is proposed based on the top level requirement on the fault effect specified in MIL-F-8785C.

An Indexing Technique for Object-Oriented Geographical Databases (객체지향 지리정보 데이터베이스를 위한 색인기법)

  • Bu, Ki-Dong
    • Journal of the Korean association of regional geographers
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    • v.3 no.2
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    • pp.105-120
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    • 1997
  • One of the most important issues of object-oriented geographical database system is to develop an indexing technique which enables more efficient I/O processing within aggregation hierarchy or inheritance hierarchy. Up to present, several indexing schemes have been developed for this purpose. However, they have separately focused on aggregation hierarchy or inheritance hierarchy of object-oriented data model. A recent research is proposing a nested-inherited index which combines these two hierarchies simultaneously. However, this new index has some weak points. It has high storage costs related to its use of auxiliary index. Also, it cannot clearly represent the inheritance relationship among classes within its index structure. To solve these problems, this thesis proposes a pointer-chain index. Using pointer chain directory, this index composes a hierarchy-typed chain to show the hierarchical relationship among classes within inheritance hierarchy. By doing these, it could fetch the OID list of objects to be retrieved more easily than before. In addition, the pointer chain directory structure could accurately recognize target cases and subclasses and deal with "select-all" typed query without collection of schema semantic information. Also, it could avoid the redundant data storing, which usually happens in the process of using auxiliary index. This study evaluates the performance of pointer chain indexing technique by way of simulation method to compare nested-inherited index. According to this simulation, the pointer chain index is proved to be more efficient with regard to storage cost than nested-inherited index. Especially in terms of retrieval operation, it shows efficient performance to that of nested-inherited index.

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Design of High Payload Dual Arm Robot with Replaceable Forearm Module for Multiple Tasks: Human Rescue and Object Handling (임무에 따른 하박 교체형 고 가반하중 양팔로봇의 설계: 구난 및 물체 핸들링)

  • Kim, Hwisu;Park, Dongil;Choi, Taeyong;Do, Hyunmin;Kim, Doohyeong;Kyung, Jinho;Park, Chanhun
    • The Journal of Korea Robotics Society
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    • v.12 no.4
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    • pp.441-447
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    • 2017
  • Robot arms are being increasingly used in various fields with special attention given to unmanned systems. In this research, we developed a high payload dual-arm robot, in which the forearm module is replaceable to meet the assigned task, such as object handling or lifting humans in a rescue operation. With each forearm module specialized for an assigned task (e.g. safety for rescue and redundant joints for object handling task), the robot can conduct various tasks more effectively than could be done previously. In this paper, the design of the high payload dual-arm robot with replaceable forearm function is described in detail. Two forearms are developed here. Each of forearm has quite a different goal. One of the forearms is specialized for human rescue in human familiar flat aspect and compliance parts. Other is for general heavy objects, more than 30 kg, handling with high degree of freedom more than 7.

An Efficient Flooding Scheme using Clusters in Mobile Ad-Hoc Networks (애드 혹 네트워크에서 클러스터를 이용한 효율적인 플러딩 방안)

  • Wang Gi-cheol;Kim Tae-yeon;Cho Gi-hwan
    • Journal of KIISE:Information Networking
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    • v.32 no.6
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    • pp.696-704
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    • 2005
  • Flooding is usually utilized to find a multi hop route toward the destination which is not within transmission range in Ad Hoc networks. However, existing flooding schemes deteriorate the network performance because of periodic message exchanges, frequent occurrence of collisions, and redundant packet transmission. To resolve this, a flooding scheme using on demand cluster formation is proposed in this paper. The scheme employs ongoing Packets for constructing a cluster architecture as the existing on demand clustering scheme. Unlike to the existing on demand clustering scheme, the scheme makes use of unicast packet transmission to reduce the number of collisions and to find the flooding candidates easily. As a result, the proposed scheme yields fewer flooding nodes than other schemes. Simulation results proved that the proposed scheme reduces the number of transmissions and collisions than those of two other schemes.