• The Korean Journal of Physiology and Pharmacology
• /
• v.20 no.1
• /
• pp.111-117
• /
• 2016

Vagal nerve activity has been known to play a crucial role in the induction and maintenance of atrial fibrillation (AF). However, it is unclear how the distribution and concentration of local acetylcholine (ACh) promotes AF. In this study, we investigated the effect of the spatial distribution and concentration of ACh on fibrillation patterns in an in silico human atrial model. A human atrial action potential model with an ACh-dependent $K^+$ current ($I_{KAch}$) was used to examine the effect of vagal activation. A simulation of cardiac wave dynamics was performed in a realistic 3D model of the atrium. A model of the ganglionated plexus (GP) and nerve was developed based on the "octopus hypothesis". The pattern of cardiac wave dynamics was examined by applying vagal activation to the GP areas or randomly. AF inducibility in the octopus hypothesis-based GP and nerve model was tested. The effect of the ACh concentration level was also examined. In the single cell simulation, an increase in the ACh concentration shortened $APD_{90}$ and increased the maximal slope of the restitution curve. In the 3D simulation, a random distribution of vagal activation promoted wavebreaks while ACh secretion limited to the GP areas did not induce a noticeable change in wave dynamics. The octopus hypothesis-based model of the GP and nerve exhibited AF inducibility at higher ACh concentrations. In conclusion, a 3D in silico model of the GP and parasympathetic nerve based on the octopus model exhibited higher AF inducibility with higher ACh concentrations.

• Journal of the Korea Society for Simulation
• /
• v.21 no.3
• /
• pp.25-33
• /
• 2012

Ptak & Smith published ORLICKY'S Material Requirement Planning Third Edition in 2011 to correspond the rapidly changed market demand by improving the original MRP based on Theory of Constraints(TOC) replenishment inventory management. This study is to develop the simulation model to decide the proper target inventory level for TOC replenishment inventory management using system dynamics Vensim software. This study shows that the proper target replenishment level is how much significant to manage the inventory by the random sample data simulation. This simulation model will be extended to compare the results of the TOC replenishment inventory management planning with the results of the old MRP planning by the enterprise actual inventory data.

• Journal of Biomedical Engineering Research
• /
• v.15 no.3
• /
• pp.237-244
• /
• 1994

We investigated the qualitive and quantitative properties in EEG signal which responds to auditory stimulus with increaing the sound-cutting frequency from 2 Hz to 20 Hz by 2 Hz step units, by chaotic dynamics. To bigin with, general chaotic properties such as fractal mechanism, 1 If frequency spectrum and positive Lyapunov exponent are discussed in EEG signal. For evoked potential with given auditory stimulus, the route to chaos by bifurcation diagram and the changes in geometrical property of Poincare sections of 2-dimensional psedophase space is observed. For that containing spontaneous potential, seen as the random background signal, the chaotic attractors in 3-dimensional phase space are found containing the same infomation as the above mentioned evoked potential. Finally the chinges of Lyapunov exponent by various sound-cutting frequencies of stimulus and by the various spatial positions (occipital region) in a brain surface to be measured, are illustrated meaningfully.

• 제어로봇시스템학회:학술대회논문집
• /
• 1996.10a
• /
• pp.83-86
• /
• 1996

We propose a mathematical model which describes the walking behavior of a person and to analyze the effect of the personality on the dynamics of the crowd. The fundamental assumption is that the human behavior is not a random process but a deterministic process with several basic mechanisms and each fundamental mechanism is common and only the parameter is different from person to person. The proposed model is based on the servomechanism which drives a person along the planned path from point to point. This model has been applied to simulate the walks of people in a crowd and the simulated results have a good coincidence with actual measurement.

• 제어로봇시스템학회:학술대회논문집
• /
• 2003.10a
• /
• pp.2335-2339
• /
• 2003

To prevent the critical situation due to the fault in the aircraft sensor system, the fault tolerant system with triple or quadruple redundancy can be made. However, if the faults are occurred in two or more than sensors simultaneously, the conventional fault detection process, such as cross-channel monitoring, may give the wrong fault alarm. For this case, we can detect the fault by estimating the state vector based on the system dynamics model, which is nonlinear for aircraft. In this paper, we propose the unscented Kalman filter to estimate the nonlinear state vector. This filter utilizes the so-called unscented transformation of sigma points featured the statistical characteristics of the random variable. For verification, we perform the simulations for F-16 aircraft with accelerometers, gyros, GPS and air data system.

• 제어로봇시스템학회:학술대회논문집
• /
• 2003.10a
• /
• pp.1504-1508
• /
• 2003

The functional behavior of each body segments were investigated with respect to human standing posture when they were exposed to the horizontal vibration in the sagittal plane. This study is processed by experimental approach. The data is analyzed, both in the time domain and in the frequency domain. Random and multisinusoidal vibration was used as input. The ankle, hip, and head were employed as the significant body segments. High relative movements were present between hip and head, and there was no significant relationship between ankle and head. Variations of visual input produced a significant postural effect.

• Advances in aircraft and spacecraft science
• /
• v.5 no.2
• /
• pp.165-175
• /
• 2018

Jet Propulsion Laboratory has traditionally performed system level vibration testing of flight spacecraft. There have been many discussions in the aerospace community for more than a decade about spacecraft vibration testing benefits or lack thereof. The benefits and potential issues of fully assembled flight spacecraft vibration testing are discussed herein. The following specific topics are discussed: spacecraft screening test to uncover workmanship problems for launch dynamics environments, force- and moment-limited vibration testing, potential issues with structural frequency identification using base shake test data, and failures related to vibration shaker testing and ways to prevent them.

• International Journal of Automotive Technology
• /
• v.8 no.4
• /
• pp.455-465
• /
• 2007

The bushing element shows nonlinear characteristics in both displacements and frequencies, also with hysteretic responses for repeated vibrational excitations. Since the characteristics of the rubber bushing significantly affects the accuracy of the vehicle dynamic simulation result, it should be accurately modeled in the vehicle suspension model. To develop an accurate bushing model for vehicle dynamics analysis, the bushing characteristics under several excitation inputs must be known. In this paper, a 3-axis tester was used to capture the bushing characteristics. The random inputs, sine inputs, and step inputs were imposed on each axis of the bushing. Also, two-axis inputs, the radial-axial and radial-normal inputs, were simultaneously imposed on the tester. Three-axis inputs including the radial-axial-normal direction were supplied to the tester. Bushing characteristics of each case were precisely analyzed. These results could be available for dynamic modeling of bushing.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.25 no.2
• /
• pp.69-79
• /
• 2011

This paper proposes a new fuzzy speed control method based on Takagi-Sugeno fuzzy method of permanent magnet synchronous generators(PMSM) for variable-speed wind turbine systems. The proposed fuzzy speed controller consists of the control terms that compensate for the nonlinearity of PMSG and the control terms that stabilize the error dynamics. The conditions are derived for the existence of the proposed speed controller, and the gain matrices of the controller are given. The proposed control method can guarantee that the PMSG can effectively track the speed reference which is calculated through the MPPT control and can reduce the fluctuations of the generated power under even fast random wind conditions. To verify the performance of the proposed fuzzy speed controller, the simulation results are demonstrated.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.12 no.3
• /
• pp.170-176
• /
• 2004

MR dampers show highly nonlinear and histeretic dynamic behavior. Therefore, for a vehicle dynamic simulation with MR dampers, this dynamic characteristics should be accurately reflected in the damper model. In this paper, an artificial neural network technique was developed for modeling MR dampers. This MR damper model was successfully verified through a random input forcing test. This MR damper model can be used for semi-active suspension vehicle dynamics and control simulations with practical accuracy.