• 전기의세계
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• v.22 no.1
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• pp.35-41
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• 1973

An automatic point traffic control method is recommended for more idealistic traffic flow over coarse road netowrks. The automatic control apparatus recommended, consists of a transceiver, amplifier, digital-to-analog converter, signal light controller for emergency and steady state, and digital counter as monitor. The transmitter sends a signal to the target vy means of Microwave-FM-CW and a diode detector picks up the echo signal. Thus the operation of the entire system will be carried out through an open loop state. Some factors necessary for an ideal detector system are rapid response, longevity and stability. An analytical method of the Doppler effect substitutes the conventional frequency deviation into the amplitude of detector output. The changing rate of amplitude is proportional to the voltage of the detector output. Some induced formula from Maxwell's radiation field theory ensures this new method, and, new method, and proves the fact with an experimental data presentation. Stability depends upon Klystron as an oscillator and a diode as a detector. the transceiver installation affects on the response and sensitivity of the system. In accordance with the detector output, several targets are easily classified by amplitudes on the scope. The traffic flow, i.e., target movement which is analyzed by the amplitude method, is shown through the scope and indicates it on the digital counter. The best efficiency for the amplitude analysis can be attained through use of an antenna having the highest sensitivity.

• KSBB Journal
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• v.28 no.6
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• pp.415-422
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• 2013

Gamma irradiation (${\gamma}IR$) is widely used for radiotherapy as a treatment of cancer cells although it has a risk to damage normal cells. Inflammation is regarded as one of side effects of ${\gamma}IR$ while the effect of low dose of ${\gamma}IR$ on inflammation has not been researched well. Here, we investigated the inflammatory responses of low dose of ${\gamma}IR$ on murine spleen cells. It was evaluated if ${\gamma}IR$ affected the mitogen-induced lymphocyte proliferation, the regulation of various inflammatory cytokines (IFN-${\gamma}$, IL-2, IL-17, IL-4, IL-10), and the involvement of Ikaros and MAPK/NF-${\kappa}B$ medicated mechanism. Exposure of $^{137}Cs-{\gamma}IR$ below 2 Gy decreased the lymphocytes proliferative response to mitogens (LPS, ConA) except at the lowest dose, 0.05 Gy. IL-17, IL-2 and IL-4 mRNA increased at 0.5 and 2 Gy, but not altered at 0.05 Gy. IL-10, anti-inflammatory cytokine, increased only at 0.05 Gy. In regard to intracellular signaling, p-JNK, p-p38 and p-$I{\kappa}B{\alpha}$ were not changed, whereas the activation of ERK and Ikaros increased at the lowest dose. These results suggest that exposure of ${\gamma}IR$ less than 0.5 Gy (or below 0.05 Gy) has beneficial effects as a radiation hormesis on immune function.

• The Journal of the Acoustical Society of Korea
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• v.14 no.5
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• pp.36-43
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• 1995

This paper presents the lousing characteristics and the time. response of ultrasonic focusing transducer which is a coupled system with an electromechanical and an acoustical component. The Finite Element Method and the Hybrid Type Infinite Element Method are applied for the analysis. The position of the focal points and the resolutions is obtained from the loosing characteristics and the time response. It is found that the transducer with the damper, which stabilizes the displacement of the radiation surface, gives a better resolution. In conclusion, the results could be applied to the design and the performance analysis of the ultrasonic focusing transducer.

• Journal of Sensor Science and Technology
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• v.6 no.6
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• pp.483-490
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• 1997

Thin film Si has been used in sensors, radiation detectors, and solar cells. The carrier mobility of thin film Si influences the device behavior through its frequency response or time response. Since poly-Si shows the higher mobility value, a-Si:H films on Mo substrate were subjected to various crystallization treatments. Consequently, we need to find an appropriate method in mobility measurement before and after the anneal treatment. This paper investigates the carrier mobility improvement with anneal treatments and summarizes the mobility measurement methods of the a-Si:H and poly-Si film. Various techniques were investigated for the mobility determination such as Hall mobility, HS, TOF, SCLC, TFT, and TCO method. We learned that TFT and TCO method are suitable for the mobility determination of a-Si:H and poly-Si film. The measured mobility was improved by $2{\sim}3$ orders after high temperature anneal above $700^{\circ}C$ and grain boundary passivation using an RF plasma rehydrogenation.

• Korean Journal of Head & Neck Oncology
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• v.4 no.1
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• pp.13-19
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• 1988

Brachytherapy is known to be a good modality to achieve local control as a boost treatment following limited external irradiation, which may reduce the external beam related acute radiation sickness, particularly in head and neck cancer. The authors developed iridium-192 ribbons recently to replace the radium needles. Total of 13 head and neck cancer patients had been treated with Ir-192 ribbons during last one year from October 1986 to September 1987, and the results were analysed to assess the applicability of the fabricated sources. The conclusion is as follows; 1) Iridium implant achieved 54% (7/13) of complete response and 69% (9/13) of overall response rate in head and neck cancer. 2) Iridium is superior to radium and cecium in brachytherapy because of easier to use and lesser exposure to the personnel. 3) Afterloading technique is useful to modify dose distribution, to expand treatment site and method, and to develop interstitial hyperthermia.

• Journal of Haehwa Medicine
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• v.9 no.2
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• pp.211-221
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• 2001

A literature study on oncological immune therapy was done, and the results were as follows. 1. Oncological immune therapy is classified as specific non specific therapy or active inactive therapy, and in tumor immune response, cellular immunity operates mainly, so activity of T lymphocytes and macrophages are closely related with growth, progress, metastasis and prospect of tumor. Recently, Immune therapies of gene which use cytokines and HLA-B7 are carrying out. 2. In oriental medicine, development of disease is closely related to up and down of healthy qi, so healthy qi operates as a immune factor and resistance factor. 3. On the base of theory "Increasing healthy qi reduces mass(養正則積自除)", strengthening body resistance is emphasized in cancer therapy. Also strengthening body resistance activates cellular immune response and promote killing tumor facility of T-cell. 4. In clinical view, using immune therapy after operation, radiation, and chemotheraphy is more effective than immune therapy itself, so it is expected that east-west cooperation will be effective in cancer therapy. 5. The study of oncological immunity is progressed on emphasizing T-cell and it is related to oriental medical theory "strengthening healthy qi to eliminate pathogen(扶定祛邪)" and advanced study is expected in future.

• Journal of the Earthquake Engineering Society of Korea
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• v.19 no.4
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• pp.145-159
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• 2015

A seismic response analysis method for three-dimensional floating offshore structures due to seaquakes is developed. The hydrodynamic pressure exerted on the structure is calculated taking into account the compressibility of the sea water, the fluid-structure interaction, the energy absorption by the seabed, and the energy radiation into infinity. To validate developed method, the hydrodynamic pressure induced by the vibration of a floating massless rigid circular disk is calculated and compared with an exact analytical solution. The developed method is applied to seismic analysis of a support structure for a floating offshore wind turbine subjected to the hydrodynamic pressures induced from a seaquake. Analysis results show that earthquake response of a floating offshore structure can be greatly influenced by the compressibility of fluid, the depth (natural frequencies) of the fluid domain, and the energy absorption capacity of the seabed.

• Nuclear Engineering and Technology
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• v.53 no.6
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• pp.1979-1990
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• 2021

Evacuation Time Estimate (ETE) can provide decision-makers with a likelihood to implement evacuation of a population with radiation exposure risk by a nuclear power plant. Thus, the ETE is essential for developing an emergency response preparedness. However, studies on ETE have not been conducted adequately in Korea to date. In this study, different cohorts were selected based on assumptions. Existing local data were collected to construct a multi-model network by TSIS-CORSIM code. Furthermore, several links were aggregated to make simple calculations, and post-processing was conducted for dealing with the stochastic property of TSIS-CORSIM. The average speed of each cohort was calculated by the link aggregation and post-processing, and the evacuation time was estimated. As a result, the average cohort-based evacuation time was estimated as 2.4-6.8 h, and the average clearance time from ten simulations in 26 km was calculated as 27.3 h. Through this study, uncertainty factors to ETE results, such as classifying cohorts, degree of model complexity, traffic volume outside of the network, were identified. Various studies related to these factors will be needed to improve ETE's methodology and obtain the reliability of ETE results.

• Journal of Digestive Cancer Research
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• v.10 no.2
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• pp.65-73
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• 2022

A breakthrough in immunotherapy has changed the outlook for metastatic colorectal cancer (mCRC) treatment as the immune surveillance evasion mechanism of tumor cells has been continuously elucidated. Immune checkpoint inhibitors (ICI), such as pembrolizumab, nivolumab, and ipilimumab, which block immune checkpoint receptors or ligands have been approved for the treatment of mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) mCRC based on numerous clinical studies. However, 50% of dMMR/MSI-H mCRC and most mismatch repair proficient/microsatellite stable mCRC remained unresponsive to current immunotherapy. Clinical trials on combination therapy that adds various treatments, such as target agents, chemotherapy, or radiation therapy to ICI, have been actively conducted to overcome this immunotherapy limitation. Further studies on safety and efficacy are needed although several trials presented promising data. Additionally, dMMR/MSI-H, tumor mutation burden, and programmed cell death ligand-1 expression have been studied as biomarkers for predicting the treatment response to immunotherapy, but the discovery and validation of more sensitively predictable biomarkers remained necessary. Thus, this study aimed to review recent studies on immunotherapy in mCRC, summarize the efficacy and limitation of immunotherapy, and describe the biomarkers that predict treatment response.

• International Journal of Computer Science & Network Security
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• v.24 no.4
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• pp.87-106
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• 2024

Vehicle-to-Home (V2H) and Home Centralized Photovoltaic (HCPV) systems can address various energy storage issues and enhance demand response programs. Renewable energy, such as solar energy and wind turbines, address the energy gap. However, no energy management system is currently available to regulate the uncertainty of renewable energy sources, electric vehicles, and appliance consumption within a smart microgrid. Therefore, this study investigated the impact of solar photovoltaic (PV) panels, electric vehicles, and Micro-Grid (MG) storage on maximum solar radiation hours. Several Deep Learning (DL) algorithms were applied to account for the uncertainty. Moreover, a Reinforcement Learning HCPV (RL-HCPV) algorithm was created for efficient real-time energy scheduling decisions. The proposed algorithm managed the energy demand between PV solar energy generation and vehicle energy storage. RL-HCPV was modeled according to several constraints to meet household electricity demands in sunny and cloudy weather. Simulations demonstrated how the proposed RL-HCPV system could efficiently handle the demand response and how V2H can help to smooth the appliance load profile and reduce power consumption costs with sustainable power generation. The results demonstrated the advantages of utilizing RL and V2H as potential storage technology for smart buildings.