• Asian-Australasian Journal of Animal Sciences
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• v.23 no.5
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• pp.640-648
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• 2010

Insulin-responsive glucose transporter 4 (GLUT4) is a member of the glucose transporter family and mainly presents in skeletal muscle and adipose tissue. To clarify the molecular structure of porcine GLUT4, RACE was used to clone its cDNA. Several cDNA clones corresponding to different regions of GLUT4 were obtained by amplifying reverse-transcriptase products of total RNA extracted from Landrace porcine skeletal muscles. Nucleotide sequence analysis of the cDNA clones revealed that porcine GLUT4 cDNA was composed of 2,491 base pairs with a coding region of 509 amino acids. The deduced amino acid sequence was over 90% identical to human, rabbit and cattle GLUT4. The tissue distribution of GLUT4 was also examined by Real-time RT-PCR. The mRNA expression abundance of GLUT4 was heart>liver, skeletal muscle and brain>lung, kidney and intestine. The developmental expression of GLUT4 and insulin receptor (IR) was also examined by Real-time RT-PCR using total RNA extracted from longissimus dorsi (LM), semimembranosus (SM), and semitendinosus (SD) muscle of Landrace at the age of 1, 7, 30, 60 and 90 d. It was shown that there was significant difference in the mRNA expression level of GLUT4 in skeletal muscles of Landrace at different ages (p<0.05). The mRNA expression level of IR also showed significant difference at different ages (p<0.05). The developmental change in the mRNA expression abundance of GLUT4 was similar to that in IR, and both showed a higher level at birth and 30 d than at other ages. However, there was no significant tissue difference in the mRNA expression of GLUT4 or IR (p>0.05). These results showed that the nucleotide sequence of the cDNA clones was highly identical with human, rabbit and cattle GLUT4 and the developmental change of GLUT4 mRNA in skeletal muscles was similar to that of IR, suggesting that porcine GLUT4 might be an insulin-responsive glucose transporter. Moreover, the tissue distribution of GLUT4 mRNA showed that GLUT4 might be an important nutritional transporter in porcine skeletal muscles.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.10
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• pp.1409-1415
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• 2021

The Gysel divider has the advantage of easily setting the resistor in the circuit. If the line impedance in the Gysel divider is set differently, the input signal can be distributed to the two output ports at various distribution ratios. This paper proposes the Gysel divider that can change the power distribution to 1:3 or 3:1 by changing the line impedance. The impedance change of the line can be implemented by placing a floating copper plate on the bottom of the microstrip-line. When the floating copper plate and the ground plane are connected, the line operates as the microstrip-line, and when the floating copper plate and the ground plane are disconnected, the line operates as the coplanar-line. The proposed Gysel divider was fabricated at the center frequency of 1.5GHz. The fabricated 3:1 Gysel divider has a stable value S₁₁ of below -17dB, S₂₁/S₃₁ of 4.8±0.2dB, S₂₁(to high output port) of -1.39±0.12dB and S₃₁(to low output port) of -6.15±0.08dB over 1.3~1.7GHz.

• The Journal of Industrial Distribution & Business
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• v.1 no.1
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• pp.33-41
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• 2010

In the age of globalization, effective and efficient corporate management is becoming more important as domestic and international business circumstances changes. In the middle of endless changes in business circumstances, fast reaction to customers and market, and offering customized goods and service became essential. In this respect, CRM designed to utilize customer information scientifically and systematically, has become an essential system and marketing strategy to enhance corporate competitiveness. CRM has placed the importance of customers in the front of marketing and has focused every process and business minds on customers. Recent change in the market and the trend of establishing and introducing CRM system has lead us to concentrate on the introduction of CRM in the financial institutions. This study searched for several views about CRM in academic and industrial papers. Through theoretical approach on CRM, the background of the introduction of CRM, the purpose of CRM, the characteristic and application of CRM, and the expected effect of CRM will be discussed. This study is focused on financial institutions where CRM is widely used. And through documents about examples of the introduction of CRM, the status of the establishment of domestic CRM and the necessity and trend of CRM will be discussed. Also the problem of CRM in the financial institutions and the improvement of CRM in domestic banks will be analyzed. When discussing CRM in the financial area, customers are the main source of corporate profit and through relationship management with the customers enhancing loyalty and maximizing profit can be obtained. Especially in CRM in financial institutions, maintaining existing customers makes higher profit ratio, so repurchasing and cross selling becomes important for obtaining lifetime value of existing customers who contribute to most of the profit of corporations. As a result, CRM should be completely customer oriented. CRM in financial institutions is not merely marketing work, but organizational competence which is made up of standardized work process through total process integration inside the corporation. Corporations which plan to introduce CRM should analyze the characteristics and conditions of corporations and establish purpose and strategy of CRM. And they need long term view to find out the factors which best fit for the introduction of CRM. To enable this, strategy composed of daily marketing activity and CRM concept is necessary. Also continued improvement through drill and training for operating organization should be followed to maintain CRM well. And corporate culture must settle customer as the center of corporate value. The race for introducing and improving CRM has already begun. CRM should not be regarded as a choice. It should be accepted as something essential. In this reality financial institutions should solve subdivision problem of customers and necessity of customers with the mind of 'customer's profit is my profit'. Customer focused management should not be emphasized only by words. Efforts like viewing from the customer's point must be nurtured to provide methods to help customers. That is, we should not just follow what is done in foreign countries. We should solve the problem of our customers according to the situation of our country, our industry, our corporation. Then we can gain the trust of customers, and the value derived from the customers will become the background of CRM which will lead the corporation to success.

• Research in Plant Disease
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• v.25 no.4
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• pp.164-172
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• 2019

Rice blast disease caused by Magnaporthe oryzae is the most important disease of rice in both South and North Korea. Cultivation of disease-resistant cultivar is the best way to prevent this notorious disease, but M. oryzae races have been continuously changed to adapt a new cultivar. Therefore, it is important to get the information about the race and avirulence genes of the pathogen for developing blast-resistant rice cultivar. Since the entrance of North Korea was prohibited, the information about the races of M. oryzae in North Korea border areas and South Korea was collected to get the information about the diversity of rice blast pathogen in North Korea. The disease occurrence on monogenic lines carrying single resistant gene was investigated in Jeonju, Suwon, Cheorwon, Goseong, and Baengnyeongdo in Korea, and Dandong in China. The monogenic lines in Jeonju and Suwon showed diverse ranges of the response, while those in Baengnyeongdo and Dandong showed relatively high resistant responses to rice blast. All the field isolates of M. oryzae were characterized for rice blast races by the Korean differential varieties and screened for known avirulence genes to determine the spatial distribution of avirulence genes and the population of M. oryzae.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.8
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• pp.1134-1142
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• 2008

Cationic amino acid transporter $b^{0,+}AT$ (HGMW-approved gene symbol SLC7A9, solute carrier family 7, member 9) plays a crucial role in amino acid nutrition. In the present study, we describe the cloning and sequencing of porcine $b^{0,+}AT$. Based on the sequence of porcine $b^{0,+}AT$ deposited in the NCBI (National Center for Biotechnological Information), we identified a putative porcine homologue. Using rapid amplification of cDNA ends (RACE), the full-length cDNA encoding porcine $b^{0,+}AT$ was isolated. The porcine $b^{0,+}AT$ cDNA was 1,680 bp long, encoding a 487 amino acid trans-membrane protein. The predicted amino acid sequence was found to have 88.9% and 87.1% identity with human and mouse $b^{0,+}AT$, respectively. Real-time RT-PCR indicated porcine $b^{0,+}AT$ transcripts expressed in heart, kidney, muscle and small intestine. The small intestine had the highest $b^{0,+}AT$ mRNA abundance while the muscle had the lowest (p<0.05). Along the longitudinal axis, the ileum had the highest $b^{0,+}AT$ mRNA abundance while the colon had the lowest (p<0.05). The $b^{0,+}AT$ mRNA level was highest on day 7 and 90 in the duodenum (p<0.05). It increased from day 1 to day 26 in the jejunum (p>0.05) and had the highest abundance on day 60 (p<0.05). There was, however, no difference between day 1, 7, 26, 30, 90 and 150 (p>0.05). The strongest $b^{0,+}AT$ expression appeared on day 7 in the ileum before weaning, and then decreased till day 30 but rose gradually again from day 60 to 150 (p<0.05).

• Maxillofacial Plastic and Reconstructive Surgery
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• v.23 no.2
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• pp.124-136
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• 2001

Heat shock protein (HSP) expression is unregulated in tumor cells and, HSP expression is likely marker of the malignant potential of oral epithelial lesion. Furthermore, the 70kDa HSP is implicated in the degree of tumor differentiation, the rate of tumor proliferation and the magnitude of the anti-tumor Immune response. Accordingly, the distribution and intensity of HSP70 and HSP47 expression was assessed in the DMBA induced oral carcinogenesis in hamster. Golden Syrian hamsters which were 3 months-age and $90{\sim}120g$ were collected. 9,10-dimethyl -1,2-benzanthracene (DMBA) in a 0.5% solution in mineral oil was painted on the buccal pouch mucosa 3 times per week in the study group. In each control and experimental groups of 6, 8, 10, 12, 14, 16, 18, 20 weeks, specimen were sectioned for immunohistochemical study with anti-HSP47 and anti-HSP70 antibody. The following results were obtained. 1. HSP47 positive cells were race or negative of normal oral mucosa, increased mildly in basal and suprabasal basal layer, and spinous cell layer after experimental 6 weeks (dysplastic or CIS stage). In CIS stage, HSP47 expression is prominent in dysplastic free or normal adjacent epithelium. 2. HSP47 positive cells in connective tissue were mainly inflammatory cells, which is gradually increased from control to precancerous and cancer stage. But HSP47 positive cells after 14 weeks were decreased, especially normal and cancer adjacent epithelium. 3. The positive staining cells of HSP70 in control, dysplastic, and CIS stage were not seen. But they were mild findings in basal layer and moderate findings in spinous layer after experimental 14 weeks (cancer stage). 4. HSP70 positive cells were increased in precancerous and cancer stage than control group in connective tissue. After experimental 16 weeks, we could not find the HSP expression in cancer cells according to cancer differentiation or cancer stage. It is concluded that HSP70 or HSP47 expression is not a definitive marker of oral malignancy or malignant potential. However, with further development, HSP immunoreactivity may be valuable as an adjunct to conventional histology for assessing the malignant potential of oral mucosal lesions.

• Journal of the Korean Association of Geographic Information Studies
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• v.19 no.1
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• pp.1-11
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• 2016

Climate change is the issue that attracts the most attention in the field of environment, as well as the most challenging task faced by the human race. There are various ways to resolve this issue. South Korea has established the primary and secondary national climate change adaptation plans at the national level, and is making it compulsory for each local government (lower and municipal-level) to establish climate change adaptation plans. Climate change vulnerability assessment plays an essential role in establishing climate change adaptation action plans. However, vulnerability assessment has a difficulty performing individual assessments since the results are produced through complex calculations of multiple impact factors. Accordingly, this study developed a web-based supporting tool(VESTAP) for climate change vulnerability assesment that can be used by lower and municipal-level local governments. The VESTAP consists of impact DB and vulnerability assessment and display tool. The index DB includes total 455 impacts of future climate data simulated with RCP (Representative Concentration Pathways) 4.5 and 8.5, atmospheric environment data, other humanities and social statistics, and metadata. The display tool has maximized convenience by providing various analytical functions such as spatial distribution, bias and schematization of each vulnerability assessment result. A pilot test of health vulnerability assessment by particulate matters in Sejong Metropolitan Autonomous City was performed using the VESTAP, and Bukang-myeon showed the highest vulnerability. By using the developed tool, each local government is expected to be able to establish climate change adaptation action plans more easily and conveniently based on scientific evidence.

• Korean Journal of Social Welfare
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• v.69 no.1
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• pp.103-123
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• 2017

This article examines the existing literature on the intersection of care and migration in Europe and the potential contributions of the Korean case. The paper reviews the three bodies of research: care, migration and their intersections. When defined as social reproductive labour, the concept of care not only captures individual/family level of experiences but it can also be an effective tool to analyse the diversity of the welfare state and the path of its evolution. Furthermore, in the context of globalisation and international migration, the concept of care can help overcome so-called 'the methodological nationalism' in the welfare state research. Accumulated evidence shows that only by applying a transnational perspective to the relationship between such social realities as class, gender and race, can we properly examine the dynamics of care distribution. Existing care-migration nexus research has found a widely observed trend of the 'migrantisation of care' in European welfare states; however, the actual modality of care-migration intersection varies reflecting historical and institutional contexts. This is why care-migration nexus research must go beyond the well-known welfare regime types. The Korean case can expand the geographical coverage and theoretical applicability of the intersection research by including a new welfare state regime type (productivist or developmental welfare states) and new patterns of migration (co-ethnic migration and marriage migration) which were rarely dealt with in this scholarship.

• Clinical and Experimental Reproductive Medicine
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• v.36 no.1
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• pp.71-80
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• 2009

Objective: PCOS is one of the most common endocrine disorder affecting reproductive age women. It shows wide range of reproductive and metabolic manifestations. This study was to determine the differences of clinical and laboratory characteristics between adolescent and adult Korean Daegu Kyungpook PCOS patients. We also compared clinical and laboratory values of Korean PCOS patients to Turkish and American PCOS patients. Methods: 88 cases were diagnosed and enrolled as PCOS patients, based on 2003 Rotterdam criteria, who visited KNUH Reproductive Endocrinology division between Jan. 2000 and Apr. 2008. We retrospectively reviewed clinical characteristics, serum hormone levels, ultrasono-graphic findings. And we divided into 2 groups, adolescent and adult. We analyzed them with Chi-square test and Student's t-test statistically. Results: There were no statistically significant differences between adult and adolescent Korean PCOS patients. The prevalence of hyperandrogenism such as facial acne or hirsutism, obesity, and insulin resistance of Korean PCOS women was significantly lower than Turkish and American PCOS women. Conclusion: From the results of this study, we can suggest that it is sure that there are differences of clinical and laboratory characteristics of PCOS patients between races. Genetic background, dietary habits and life style affect the expression of clinical symptoms of PCOS. But we could not find out the difference between adolescent and adult PCOS patients of same race. It might be due to the limitation of small patient number and narrow range of age distribution. So, there must be large scale and multi-center and multi-regional study.

• Journal of the Korean Society of Radiology
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• v.14 no.5
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• pp.685-693
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• 2020

This study was performed to compare the differences between total fat area, subcutaneous fat area and visceral fat area according to L1-S1 inter vertebral disc level in asymptomatic Korean patients with non-contrast abdominal CT scan. The location of the maximum fat ratio of the total fat area is the total fat area measured in male L2-3, L3-4, L4-5, female L4-5, and L5-S1. The location showing the maximum fat ratio of the subcutaneous fat area is the subcutaneous fat area measured in male L4-5, and the woman is the subcutaneous fat area measured in L4-5 and L5-S1. The location of the maximum fat ratio of visceral fat area was the visceral fat area measured in L1-2 and L2-3 males, and there was no difference in visceral fat area according to the measured position in females. Although abdominal fat measurement is common at the L4-5 inter vertebral disc level, fat distribution varies widely depending on nationality, race, and gender. Therefore, it is necessary to analyze through the research data which location to choose according to the research purpose, and to mention why the location is appropriate.