• Asian Oncology Nursing
• /
• v.11 no.3
• /
• pp.171-178
• /
• 2011

Purpose: This literature review was conducted to provide a summary of the findings from research on knowledge and attitudes about human papilloma virus (HPV) and HPV vaccination, and studies of its actual uptake among women in Asian countries. Methods: The author searched the Pubmed, CINAHL, and KISS electronic databases to identify peer-reviewed articles published between 2006 and 2011. Results: Seventeen peer-reviewed studies met the inclusion criteria (13 quantitative, 4 qualitative). Findings from seven Asian countries that measured female adult's knowledge of HPV related issues and attitudes toward HPV vaccination were reviewed. Low level of knowledge about HPV and its related conditions, willingness to be vaccinated, and low uptake of vaccines were identified across the studies. Cultural barriers and social stigmatization about HPV vaccination were also discussed. Conclusion: Findings from this review indicate that adult women in Asian countries are in urgent need of improving HPV related knowledge and its actual vaccination. Policy makers, health care providers, and public health educators should take into account the cultural barriers and attitudes toward HPV vaccination in the process of developing and implementing educational programs and interventions for adult women in Asian countries.

• Journal of Korean Traditional Oncology
• /
• v.19 no.1
• /
• pp.1-24
• /
• 2014

Objectives : The purpose of this study was to present the clinical guidelines for gastric cancer. Methods : The literature on Western and Oriental medical treatment of gastric cancer were collected, analyzed and summarized from the Google Scholar, KIOM OASIS and PUBMED from 1993 to 2014. Results : Gastric cancer is the second most common cancer in Korea. In recent studies, applying integrative oriental and western medicine can suppress the tumor, improve the survival, the immune system, and the quality of life in gastric cancer. But there isn't still a unified protocol for gastric cancer treatment, so we have difficulty in clinical application. This study will be helpful for understanding and building systems for integrative gastric cancer treatment. Conclusion : Further studies on integrative gastric cancer treatment are needed to improve the survival of gastric cancer patients and build the clinical practice guidelines of gastric cancer.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.2
• /
• pp.1043-1047
• /
• 2013

Although there have been many studies investigating possible associations between the C1653T mutation and risk of HCC, the results have been inconsistent. We conducted searches of the published literature in Pubmed and Embase databases up to January 2013. Seventeen studies with a total of 1,085 HCC cases and 1,365 healthy controls were retrieved. We found a significant association between the C1653T mutation and HCC risk (OR = 2.01, 95%CI= 1.49-2.70). In the subgroup analysis by ethnicity, a significant association was also found in Asians (OR = 2.07, 95%CI= 1.71-2.51). In subgroup analysis by HBV genotype, B and C were linked with development of HCC (B:OR = 2.21, 95%CI= 1.13-4.34; C:OR = 2.26, 95%CI= 1.61-3.16). However, no significant association was found between the C1653T mutation and HCC risk in HBeAg positive cases. In conclusion, this meta-analysis suggests that the C1653T mutation may be associated with susceptibility to HCC.

• Journal of TMJ Balancing Medicine
• /
• v.4 no.1
• /
• pp.5-7
• /
• 2014

Objectives: Neurological examination on balance function is widely applied in clinical practice. Balance function may be clinically relevant to an assessment of yinyang balance in such therapies as temporomandibular joint balancing medicine. Fukuda stepping test is a relatively not-well-known method of balance function test. This study reviewed the procedures and criteria of Fukuda stepping test. Method: Recent articles on Fukuda stepping test were searched in public database (Pubmed, Proquest) and reviewed for its procedures and clinical implications. Results: Fukuda stepping test adopts 50 steps or 100 steps with subsequent assessment of the deviation or displacement of the subject. It may not be reliable during acute phase. Conclusion: Fukuda stepping test may be utilized and be further developed to assess balance function in the neurological management of functions.

• The Journal of Korean Medicine
• /
• v.31 no.5
• /
• pp.12-32
• /
• 2010

Objective: This study aimed to review herbal remedy-based RCTs on cancer patients in order to produce helpful information for clinical study of herbal medicine in the future. Methods: We collected all RCTs using herbal remedies on cancer patients from Pubmed and Cochrane databases until November 1st, 2009. Elementary information such as nation where performed, clinical question, design, randomization, double-blinding and allocation concealment were analyzed. Results: 153 RCTs were finally selected. 119 RCTs were conduced in China while only 2 were done in Korea. The most frequent targeted cancer was lung cancer as 29 RCTs. The main clinical questions included improvement of quality of life, elongation of survival rate and regression of tumor being 83, 62 and 55 respectively. 112 RCTs used herbal remedies with western therapy. Adequate methods for randomization and allocation concealment were found in 37% and 10% of trials respectively. Conclusions: We found that herbal remedies are used on cancer patients in aspects of both caring for the human body and tumor treatment itself. The study might provide us useful data for cancer-related clinical study using herbal remedies in the future.

• The Journal of Internal Korean Medicine
• /
• v.36 no.2
• /
• pp.153-164
• /
• 2015

Objectives: The aim of this study was to collect and analyze studies on acupuncture therapies for treatment of voiding difficulty in stroke patients and to suggest methods of study for acupuncture therapies. Methods: Electronic searches were performed on search sites including NDSL, 국회도서관, RISS4U, DBPIA, KISS, KMBASE, KoreaMed, 한국전통지식포탈, OASIS, Pubmed, CNKI, using the search words ‘중풍’, ‘뇌졸중’, ‘stroke’, ‘배뇨장애’, ‘voiding’, ‘urinary’, ‘incontinence’, ‘retention’, ‘ ’, ‘침치료’, and ‘acupuncture’ as single or combined keywords, from January 1990 to August 2013 with language limitation, Korean, English, Chinese. Also, quality of the studies were evaluated using Jadad score. Results: The searches identified 16 studies for selection and analysis. In the present study, voiding difficulty includes urinary incontinence and urinary retention. The acupuncture points CV4, SP6, and CV3 were the most frequently used. Treatments were most frequently applied daily. The times and terms of acupuncture treatment, were most frequently 30 minutes per treatment for 4 weeks Conclusions: The acupuncture therapies were effective in the treatment of voiding difficulty in stroke patients, but the study of acupuncture therapy as a treatment for this issue in stroke patients needs to be standardized and high-quality study models should be introduced.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.31 no.3
• /
• pp.20-32
• /
• 2018

Objectives: The purpose of this study is to identify the effectiveness of fumigation treatment, provide a clinical basis for fumigation therapy, and develop treatment protocols through consideration of treatment methods and herbal medicines. Methods: We searched for randomized controlled clinical trials using fumigation treatment on mycotic vaginitis in 8 electronic databases such as EMBASE, Pubmed, and CNKI. The results of the studies were analyzed and the risk of bias was assessed by using Cochrane risk of bias tool. A meta-analysis was performed to reveal the effectiveness of fumigation compared to control treatments. Results: We finally selected 5 studies among 54 articles according to inclusion criteria and exclusion criteria. In all selected studies, herbal fumigation was more effective than any control treatment and all the studies were statistically significant. Conclusions: The study provides a basis for applying fumigation treatment to patients with mycotic vaginitis and helps developing a treatment protocol of caring patients of mycotic vaginitis. But the limitation of this study is that the number of studies included is small and quantitative synthesis of all results has not been achieved.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.30 no.3
• /
• pp.166-181
• /
• 2017

Objectives : The study was done to verify the relation between early-onset androgenetic alopecia(AGA) and metabolic syndrome(MetS). Methods : Data were collected through electronic database including KoreaMed, National Assembly Library, KMBASE, NDSL, KCI, KERIS, Google Scholar, Pubmed, Cochrane CENTRAL and EBSCO MEDLINE. A total of 13 case-control studies related to the MetS of early-onset alopecia patients were used for the systematic review and meta-analysis. Risk of bias of included studies were assessed by RoBANS tool. RevMan5.3, CMA3 were used for the meta-analysis. Results : In 13 evaluated articles, most frequent bias was the participant selection bias that was found in 10 articles. Significant association between early-onset AGA and MetS was found in 10(76.9%) out of 13 articles in the systematic review. In meta-analysis, early-onset male AGA was associated with increased risk of metabolic syndrome(OR: 3.73, 95% CI:2.49 -5.61). Conclusions : AGA, particularly early -onset male AGA, is significantly associated with MetS. Therefore all patients with early onset male AGA should be suggested to take preventive treatment to reduce the risk of MetS and various problems associated with it.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.31 no.4
• /
• pp.22-30
• /
• 2018

Objectives : The aim of this study is to investigate the relationship between chronic low grade inflammation theory, psoriasis, and herbal medicine. Methods : We reviewed recent studies on the relationship between chronic low-grade inflammation, psoriasis, and herbal medicine through Pubmed. Results : The pathological basis for psoriasis is the action of inflammatory mediators by the activation of the immune response, which can be a cause of various cardiovascular, metabolic and psychological symptoms of psoriasis patients, in addition to skin lesions. The herbal medicines improve these inflammatory conditions and improve local lesions through herbal medicine such as Qingdai, which have a strong inhibitory effect on IL-17,22 production. Conclusions : Herbal medicines used in psoriasis are thought to be effective not only for the improvement of local psoriasis lesions through anti-inflammatory effect but also for the improvement of systemic inflammation associated with chronic low grade inflammation.

• Journal of Haehwa Medicine
• /
• v.20 no.2
• /
• pp.91-98
• /
• 2012

Objective : This is a comprehensive review summary of anticancer effect through autophagy using herb. Method : Data were retrieved from pubmed and authorized texts concerning anticancer effect through autophagy using herb.g its ant Results : A total of 5 potentially relevant studies were identified with including 4 in vitro papers. All papers were related to single herb extract or its compound providini-cancer effect through autophagy mechanisms of up-regulated pro-autophagy proteins and down-regulated anti-autophagy proteins. Conclusion : We can search five potentially relevant studies with anticancer treatment through enhancing autophagy mechanism. Autophagy will be a good pathway mechanism to explore novel experimental therapeutics in herb.