• Communications of the Korean Mathematical Society
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• v.12 no.3
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• pp.717-723
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• 1997

The compact transformation group has been developed with lots of properties. Many properties which are satisfied on G-space for compact group G do not hold for noncompact case. To recover some theory on spaces with noncompact group action we give some restriction on G-spaces. Hence we introduced Cartan G-spaces and proper G-spaces for our goal and we prove some properties on these G-spaces with noncompact G.

• Bulletin of the Korean Mathematical Society
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• v.40 no.2
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• pp.309-317
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• 2003

In this paper we study the relation of Euler characteristic with respect to cohomology with compact support in F$_{p}$-coefficient for the fibration of ENR's and generalize some properties on proper G-spaces for locally compact Lie group G.G.

• Bulletin of the Korean Mathematical Society
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• v.31 no.2
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• pp.167-172
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• 1994

For a given $C^{*}$-dynamical system (A, G, .alpha.) with a G-simple $C^{*}$-algebra A (that is A has no proper .alpha.-invariant ideal) many authors have studied the simplicity of a $C^{*}$-crossed product A $x_{\alpha{r}}$ G. In [1] topological freeness of an action is shown to guarantee the simplicity of the reduced $C^{*}$-crossed product A $x_{\alpha{r}}$ G when A is G-simple. In this paper we investigate the pure infiniteness of a simple $C^{*}$-crossed product A $x_{\alpha}$ G of a purely infinite simple $C^{*}$-algebra A and a topologically free action .alpha. of a finite group G, and find a sufficient condition in terms of the action on the spectrum of the multiplier algebra M(A) of A. Showing this we also prove that some extension of a topologically free action is still topologically free.

• Bulletin of the Korean Mathematical Society
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• v.30 no.2
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• pp.193-199
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• 1993

A hereditary $C^{*}$-subalgebra B of a $C^{*}$-algebra A is said to be full if B is not contained in any proper closed two-sided ideal in A, so each hereditary $C^{*}$-subalgebra of a simple $C^{*}$-algebra is always full. It is well known that every $C^{*}$-algebra is strong Morita equivalent to its full hereditary $C^{*}$-subalgebra, but the strong Morita equivalence of a $C^{*}$-algebra A and its hereditary $C^{*}$-subalgebra B does not imply the fullness of B, ingeneral. We present the following lemma for our computational convenience in the course of the proof of the main theorem. Note that $L_{B}$, $L_{B}$$^{*}$ and $L_{B}$ $L_{B}$$^{*}$ are all .alpha.-invariant whenever B is .alpha.-invariant under the action .alpha. of G.a. of G.a. of G.a. of G.f G.

• Magazine of the Korean Society of Agricultural Engineers
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• v.38 no.5
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• pp.116-124
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• 1996

The purpose of The work described in this paper is to clear up the initial moisture content, specific surface, air drying and freezing-thawing process on liquid limit of clayey soils distributed widely at estuary of three main rivers in the west coast. To this end, a series of tests were conducted on clayey soils samples with natural state and treated state. From the test results, the liquid limit was decreased with decrement of initial moisture content, air drying process, and freezing-thawing cycles and increased with increment of specific surface. The specific surface which influenced on the liquid limit is over $25 m^2$m$^2$/g, and their relationships are well formulated. Air drying process is expected to improve the engineering properties of the soils such the pro-water properties were changed to anti-water proper-ties through lowering of water holding as resulted to incline from A-7-5 to A-5 on the soil classificaction plastic chart. The freezing-thawing process decreased 20% of liquid limit, especially under the first cycle of the behavious, as a result of above mentioned reasons, phase change of soil-water system brought the decrement of specific surface and affected to the liquid limit.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.221-226
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• 2023

Proper activation and aggregation of platelets are necessary, but excessive or abnormal aggregation can lead to cardiovascular diseases such as stroke, thrombosis, and atherosclerosis. Therefore, identifying a substance that can regulate or inhibit platelet aggregation is important for preventing and treating these diseases. Several studies have shown that certain ginsenoside compounds in Panax ginseng can inhibit platelet aggregation. Among these compounds, Rk3 (G-Rk3) from Panax ginseng needs to be further explored in order to reveal the mechanisms of action during inhibition. G-Rk3 significantly increased amounts of cyclic adenosine monophosphate (cAMP) and led to significant phosphorylation of cAMP-dependent kinase substrates vasodilator-stimulated phosphoprotein and inositol 1,4,5-trisphosphate receptor. Furthermore, the effect of G-Rk3 extended to the inhibition of PI3K/Akt phosphorylation resulting in the reduced secretion of intracellular granules. Ultimately, G-Rk3 effectively inhibited platelet aggregation. Therefore, we suggest G-Rk3's potential as a prophylactic or therapeutic agent for cardiovascular diseases caused by faulty platelet aggregation.

• Structural Engineering and Mechanics
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• v.24 no.2
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• pp.155-180
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• 2006

Many applications in mechanical design involve elastic bodies coming into contact under the action of the applied load. The distribution of the contact pressure throughout the contact interface plays an important role in the performance of the contact system. In many applications, it is desirable to minimize the maximum contact pressure or to have an approximately uniform contact pressure distribution. Such requirements can be attained through a proper design of the initial surfaces of the contacting bodies. This problem involves a combination of two disciplines, contact mechanics and shape optimization. Therefore, the objective of the present paper is to develop an integrated procedure capable of evaluating the optimal shape of contacting bodies. The adaptive incremental convex programming method is adopted to solve the contact problem, while the augmented Lagrange multiplier method is used to control the shape optimization procedure. Further, to accommodate the manufacturing requirements, surface parameterization is considered. The proposed procedure is applied to a couple of problems, with different geometry and boundary conditions, to demonstrate the efficiency and versatility of the proposed procedure.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.9-10
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• 2002

Human circulatory system between heart and tissue is not directly connected in normal condition but mandatory to go through the capillary system in order to fulfill its physiologic aim to deliver oxygen and nutrients, etc. to the tissue and retrieve used blood together with waste products from the tissue properly. When abnormal connection between arterial and venous system (AV fistula), these two circulatory systems respond differently to the hemodynamic impact of this abnormal connection between high pressure (artery) and low pressure (vein) system. Depending upon the location and/or degree (e.g. size and flow) of fistulous condition, each circulatory system exerts different compensatory hemodynamic response to this newly developed abnormal inter-relationship between two systems in order to minimize its hemodynamic impact to own system of different hemodynamic characteristics. Pump action of the heart can assist the failing arterial system directly to maintain arterial circulation against newly established low peripheral resistance by the AV fistula during the compensation period, while it affects venous system in negative way with increased venous loading. However, the negative impact of increased heart action to the venous system is partly compensated by the lymphatic system which is the third circulatory system to assist venous system independently with different hemodynamics. The lymphatic system with own unique Iymphodynamics based on peristaltic circulation from low resistance to high resistance condition, also increases its circulation to assist the compensation of overloaded venous system. Once these compensation mechanisms should fail to fight to newly established hemodynamic condition due to this abnormal AV connection, each system start to show different physiologic ${\underline{de}compensation}$ including heart and lymphatic system. The vicious cycle of decompensation between arterial and vein, two circulatory system affecting each other by mutually negative way steadily progresses to show series of hemodynamic change throughout entire circulation system altogether including heart. Clinical outcome of AV fistula from the compensated status to decompensated status is closely affected by various biological and mechanical factors to make the hemodynmic status more complicated. Proper understanding of these crucial biomechanical factors iii particular on hemodyanmic point of view is mandatory for the advanced assessment of biomechanical impact of AV fistula, since this new advanced concept of AY fistula based on blomechanical information will be able to improve clinical control of the complicated AV fistula, either congenital or acquired.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2002.09a
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• pp.75-80
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• 2002

Enormous volumes of mining wastes from the abandoned and closed mines are disposed without a proper treatment at Southeastern part of Kangwon Province. Erosion of these wastes contaminates soil, surface water, and sediments with heavy metals. Objectives of this research were to fractionate heavy metals in the mine waste and to assess the potential S. P. A. G.(Soil Pollution Assesment Guidance) of each metal fraction. Mine wastes analyzed for physical and chemical properties. pH of wastes ranged from 3.3 to 8.0. Contents of total N and loss on ignition matter were in the ranges of 0.2~5.6%, and 0.8~15.3%, respectively. Heavy metals in the wastes were higher in the coal mines than those in the other mine wastes. Total concentrations of metals in the wastes were in the orders of Pb > Zn > Cu > Cd, exceeded the corrective action level of the Soil Environment Conservation Law and higher than the natural abundance levels reported from uncontaminated soils. Relative distribution of heavy metal fractions was residual > organic > reducible > carbonate > adsorbed, reversing the degree of metal bioavailability. Mobile fractions of metals were relatively small compared to the total concentrations. Soil Pollution Assesment Guidance(SPAG) values were ranged from 0.08 to 9.14 based on labile fraction of metal concentrations. SPAG values of labile concentration were lower than those of total concentration.

• Animal cells and systems
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• v.11 no.2
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• pp.129-134
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• 2007

The initiation of eukaryotic DNA replication requires assembly of the pre-replicative complex (Pre-RC) through the concerted action of Orc, Cdc6, Cdt1 and Mcm2-7 complex during G1 phase. The pre-RC assembly licenses individual replication origins for the initiation of DNA replication and sufficient number of the pre-RC is essential for proper progression of S phase. However, it is not well known how cells recognize the completion of the pre-RC assembly before G1-S transition. In order to understand the cellular responses to the defects in pre-RC assembly, we depleted the known components of pre-RC proteins using the small interference RNAs in HeLa cells. Although the defects of pre-RC assembly by the depletion of the pre-RC proteins such as Orc2, Cdt1, Mcm2 & Mcm10 did not elicit the activation of Chk1- or Chk2-dependent checkpoint pathways, these cells still showed significant decrease in the cellular level of Cdc25A proteins. These results suggests that a novel checkpoint pathway exist in HeLa cells, which is not dependent upon Chk1 or Chk2 proteins and play essential roles in the cellular responses to the defects in the pre-RC assembly. Also, among those four proteins tested in this study, the depletion of Mcm10 and Cdt1 proteins significantly increased the apoptotic cell death in HeLa cells, suggesting that these proteins not only play roles in the pre-RC assembly, but also are involved in the checkpoint responses to the defects in the pre-RC assembly.