• 제목/요약/키워드: progressive patient

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Cerebellar Liponeurocytoma with an Unusually Aggressive Histopathology : Case Report and Review of the Literature

  • Chung, Sang-Bong;Suh, Yeon-Lim;Lee, Jung-Il
    • Journal of Korean Neurosurgical Society
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    • 제52권3호
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    • pp.250-253
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    • 2012
  • We report a rare case of cerebellar liponeurocytoma with an unusually aggressive histopathology. A 49-year-old man presented with a four-month history of headache, vertigo, and progressive swaying gait. Magnetic resonance imaging showed a $3{\times}3.5cm$ sized relatively well-demarcated round mass lesion in the fourth ventricle, characterized by high signal intensity on T2-weighted images. Postcontrast images revealed strong enhancement of the solid portion and the cyst wall. The patient underwent suboccipital craniectomy and tumor removal. The pathologic diagnosis was cerebellar liponeurocytoma. Adjuvant radiotherapy was offered due to concerns related to the high proliferative index (Ki-67, 13.68%) of the tumor. At the last routine postoperative follow-up visit (12 months), the patient complained of no specific symptom and there was no evidence of tumor recurrence. However, longterm follow-up and the analysis of similar cases are necessary because of the low number of reports and the short follow-up of cases.

Thoracic Re-irradiation for Locally Recurrent Lung Cancer

  • Aktan, Meryem;Kanyilmaz, Gul;Koc, Mehmet;Aras, Serhat
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권11호
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    • pp.5041-5045
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    • 2016
  • Background: Patients with recurrent or progressive lung cancer experience a significant symptom burden, negatively affecting quality of life and reducing life expectancy. Thoracic re-irradiation can be used for palliative treatment to relieve symptoms or as a curative treatment. Methods: Using patient charts, we identified and reviewed 28 cases that had received palliative thoracic re-irradiation for recurrent lung cancer. Results: Before re-irradiation, 32% of patients had stage III non-small cell lung cancer and six had small cell lung cancer. The median interval between treatments was 18.7 months. Median follow-up was 31.2 months from the initial radiotherapy and 5 months after re-irradiation. A better performance status before re-irradiation (<80 vs >80, p=0.09) and a lower overlap 90% isodose (<70 vs >70, p=0.09) showed trends toward improved survival. Grade 1-2 toxicity from re-irradiation was recorded in 12/28 patients, and no grade 3 or 4 acute toxicity was encountered. Conclusion: The role of palliative treatment in survival is not clear but it can provide symptomatic relief in patients, with no high grade toxicity. Further studies with greater patient numbers and longer follow-up times should facilitate determination of the role of this treatment in toxicity and effects on survival.

Isolated Spinal Neurocysticercosis : Unusual Ocular Presentation Mimicking Pseudotumor Cerebri

  • Seo, Jong-Hun;Seo, Hong-Ju;Kim, Seok-Won;Shin, Ho
    • Journal of Korean Neurosurgical Society
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    • 제49권5호
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    • pp.296-298
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    • 2011
  • Spinal intradural cysticercosis is a rare manifestation of neurocysticercosis. We report a unique patient who showed visual symptoms and normal imaging of the brain caused by isolated spinal neurocysticercosis. A 59-year-old male patient was admitted to the emergency unit with a history of severe headache and progressive blurred vision. Brain computed tomographic scanning and magnetic resonance imaging showed normal cerebral anatomy without hydrocephalus. The fundoscopic evaluation by an ophthalmologist showed bilateral papilledema. Perimetry studies revealed visual field defects in both eyes. With the diagnosis of pseudotumor cerebri, a lumbar tap was attempted; however, we could not drain the cerebrospinal fluid in spite of appropriate attempts. Lumbar magnetic resonance imaging revealed multilevel intraspinal lesions that were confirmed histologically to be neurocysticercosis. An intraoperative lumbar puncture revealed an increased opening pressure and cytochemical analysis showed elevated cerebrospinal fluid protein level. The headache resolved immediately after surgery. However, the visual symptoms remained and recovered only marginally despite antihelminthic medications after six months of operation.

A Personalized Healthcare Analysis System in Ubiquitous Environment

  • Sain, Mangal;Chung, Wan-Young;Lee, Hoon-Jae
    • Journal of information and communication convergence engineering
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    • 제9권2호
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    • pp.235-243
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    • 2011
  • With the recent trends and the adaptation of further advancement in personal healthcare system leads to develop some application which can work independent and user can operate that application without much interference of physician or any specialist user. To meet these needs, this paper proposes and implements a progressive architecture for the personal healthcare information system. This new architecture will not only play the role of middleware but also provide a analysis tool to process that different sensor data which is collected from different sensors implemented on patient body and environment. After collecting that data, with the help of various developed applications this data can be convert into useful information which will be stored in application server for further use and research. These features can be enabled by simple and effortless interactions of normal users and act autonomously to support their activities. This proposed personal healthcare architecture will also provide analysis report to the doctors and patient or various users for further instructions. The analysis report consists of healthcare data analysis results and history of patients. We are considering healthcare data like ECG, which is an important aspect for basic healthcare need.

Decompressive Surgery in a Patient with Posttraumatic Syringomyelia

  • Byun, Min-Seok;Shin, Jun-Jae;Hwang, Yong-Soon;Park, Sang-Keun
    • Journal of Korean Neurosurgical Society
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    • 제47권3호
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    • pp.228-231
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    • 2010
  • Posttraumatic syringomyelia may result from a variety of inherent conditions and traumatic events, or from some combination of these. Many hypotheses have arisen to explain this complex disorder, but no consensus has emerged. A 28-year-old man presented with progressive lower extremity weakness, spasticity, and decreased sensation below the T4 dermatome five years after an initial trauma. Magnetic resonance imaging (MRI) revealed a large, multi-septate syrinx cavity extending from C5 to L1, with a retropulsed bony fragment of L2. We performed an L2 corpectomy, L1-L3 interbody fusion using a mesh cage and screw fixation, and a wide decompression and release of the ventral portion of the spinal cord with an operating microscope. The patient showed complete resolution of his neurological symptoms, including the bilateral leg weakness and dysesthesia. Postoperative MRI confirmed the collapse of the syrinx and restoration of subarachnoid cerebrospinal fluid (CSF) flow. These findings indicate a good correlation between syrinx collapse and symptomatic improvement. This case showed that syringomyelia may develop through obstruction of the subarachnoid CSF space by a bony fracture and kyphotic deformity. Ventral decompression of the obstructed subarachnoid space, with restoration of spinal alignment, effectively treated the spinal canal encroachment and post-traumatic syringomyelia.

Phlegmonous Gastritis with Early Gastric Cancer

  • Kim, Kyung Hee;Kim, Chan Gyoo;Kim, Young-Woo;Moon, Hae;Choi, Jee Eun;Cho, Soo-Jeong;Lee, Jong Yeul;Choi, Il Ju
    • Journal of Gastric Cancer
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    • 제16권3호
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    • pp.195-199
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    • 2016
  • Phlegmonous gastritis is a rare and rapidly progressive bacterial infection of the stomach wall, with a high mortality rate. Antibiotics with or without surgical treatment are required for treatment. We present a case in which phlegmonous gastritis occurred during the diagnostic evaluation of early gastric cancer. The patient showed improvement after antibiotic treatment, but attempted endoscopic submucosal dissection failed because of submucosal pus. We immediately applied argon plasma coagulation since surgical resection was also considered a high-risk procedure because of the submucosal pus and multiple comorbidities. However, there was local recurrence two years later, and the patient underwent subtotal gastrectomy with lymph node dissection. Considering the risk of incomplete treatment immediately after recovery from phlegmonous gastritis and that recurrent disease can be more difficult to manage, delaying treatment and evaluation until after complete recovery of PG might be a better option in this particular clinical situation.

Delayed Diagnosis of Probable Radiation Induced Spinal Cord Vascular Disorders

  • Won, Young Il;Kim, Chi Heon;Chung, Chun Kee;Yun, Tae Jin
    • Journal of Korean Neurosurgical Society
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    • 제57권3호
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    • pp.215-218
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    • 2015
  • Occasionally, unexpected neurological deficits occur after lumbar spinal surgery. We report a case of monoparesis after lumbar decompressive surgery. A 63-year-old man, who had undergone decompression of L4-5 for spinal stenosis 4 days previously in the other hospital, visted the emergency department with progressive weakness in the left leg and hypoesthesia below sensory level T7 on the right side. He had been cured of lung cancer with chemotherapy and radiation therapy 10 years previously, but detailed information of radiotherapy was not available. Whole spine magnetic resonance (MR) imaging showed fatty marrow change from T1 to T8, most likely due to previous irradiation. The T2-weighted MR image showed a high-signal T4-5 spinal cord lesion surrounded by a low signal rim, and the T1-weighted MR image showed focal high signal intensity with focal enhancement. The radiological diagnosis was vascular disorders with suspicious bleeding. Surgical removal was refused by the patient. With rehabilitation, the patient could walk independently without assistance 2 months later. Considering radiation induced change at thoracic vertebrae, vascular disorders may be induced by irradiation. If the spinal cord was previously irradiated, radiation induced vascular disorders needs to be considered.

Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus Patient with Delayed Improvement after Tap Test

  • Kang, Kyunghun;Hwang, Sung Kyoo;Lee, Ho-Won
    • Journal of Korean Neurosurgical Society
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    • 제54권5호
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    • pp.437-440
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    • 2013
  • The cerebrospinal fluid tap test (CSFTT) is recommended as a key step in the diagnosis of idiopathic normal pressure hydrocephalus (iNPH). While there is no generally accepted evaluation period for ascertaining a CSFTT responder, a substantial number of patients are evaluated only once within 24 hours of the test for improvement in gait. We report an iNPH patient with a favorable response to shunt surgery, who was first judged a non-responder by this standard, though subsequently was judged a responder in virtue of repetitively testing gait over 7 days. A 68-year-old man presented with progressive impairment of gait, balance, and memory. He was diagnosed as iNPH with an Evans' ratio of 0.35. At first hospitalization, change in gait was evaluated 24 hours after the CSFTT. He didn't show any significant improvement and was judged as a non-responder. However, at the second CSFTT, we repetitively tested his change in gait over seven days. Forty-eight hours after the tap, he showed significant improvement in his gait. He was then confirmed as a responder. After the operation, the gait difficulties were almost fully resolved. Further studies developing the standard procedure of the CSFTT should be considered.

Primary Glioblastoma of the Cerebellopontine Angle : Case Report and Review of the Literature

  • Lee, Ji-Hye;Kim, Jong Hyun;Kwon, Taek-Hyun
    • Journal of Korean Neurosurgical Society
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    • 제60권3호
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    • pp.380-384
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    • 2017
  • Glioblastoma multiforme (GBM) is located most frequently in the cerebral hemispheres. Glioblastoma presenting as an extraaxial mass of cerebellopontine angle (CPA) is very rare in adults. We report a rare case of GBM arising in the CPA. The patient was a 71-year-old female, who complained of progressive gait disturbance and poor memory. Initial magnetic resonance imaging (MRI) revealed a $1.4{\times}1.3cm$ mass in the left CPA, with broad base to the petrous bone, showing homogenous enhancement. Follow-up MRI showed a rapid increase in size of mass ($2.7{\times}2.2cm$) with a necrotic portion. A stereotactic biopsy was done under the guidance of navigation system, and the histopathologic diagnosis was GBM, World Heath Organization grade IV. Further surgical resection was not performed considering her general condition, and the patient underwent concurrent chemotherapy with radiation therapy. Although rare, the possibility of glioblastoma should be included in the differential diagnosis of atypical CPA tumor.

외상성으로 인한 안면마비 및 청력장애를 호소하는 환자 1례 (A Case of Facial Palsy and Hearing Disturbance Caused by Traumatic Disorder)

  • 신동길;김덕곤;김기훈
    • 대한한방소아과학회지
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    • 제17권2호
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    • pp.137-148
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    • 2003
  • Objective : Oriental medical treatment may be possible or effective in patients with facial palsy and hearing disturbance caused by traumatic disorder Methods : The authors observed objectively improvement state of patient that treated by acupuncture, herbal medicine Results : 1. A Facial nerve travel long and narrow bone canal in temporal bone. so slow progressive palsy is caused by nerve swelling and impedimental blood circulation in bone canal, if bruise happens. 2. A patient with traumatic facial palsy, acupuncture, herbal medicine(Igigeopung-tang, Boicyangwitang etc.), electro acupuncture are effective to improving symptoms. 3. Despite acupuncture treatment is taken, hearing disturbance is not improved. 4. In general, everyone consider surgical operation first of all, in the case of having traumatic facial palsy. Though this case, the author are thought that can attempt access of Oriental medical treatment without doing surgical operation.

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