DOI QR코드

DOI QR Code

Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus Patient with Delayed Improvement after Tap Test

  • Kang, Kyunghun (Department of Neurology, School of Medicine, Kyungpook National University) ;
  • Hwang, Sung Kyoo (Department of Neurosurgery, School of Medicine, Kyungpook National University) ;
  • Lee, Ho-Won (Department of Neurology, School of Medicine, Kyungpook National University)
  • 투고 : 2013.06.03
  • 심사 : 2013.11.11
  • 발행 : 2013.11.28

초록

The cerebrospinal fluid tap test (CSFTT) is recommended as a key step in the diagnosis of idiopathic normal pressure hydrocephalus (iNPH). While there is no generally accepted evaluation period for ascertaining a CSFTT responder, a substantial number of patients are evaluated only once within 24 hours of the test for improvement in gait. We report an iNPH patient with a favorable response to shunt surgery, who was first judged a non-responder by this standard, though subsequently was judged a responder in virtue of repetitively testing gait over 7 days. A 68-year-old man presented with progressive impairment of gait, balance, and memory. He was diagnosed as iNPH with an Evans' ratio of 0.35. At first hospitalization, change in gait was evaluated 24 hours after the CSFTT. He didn't show any significant improvement and was judged as a non-responder. However, at the second CSFTT, we repetitively tested his change in gait over seven days. Forty-eight hours after the tap, he showed significant improvement in his gait. He was then confirmed as a responder. After the operation, the gait difficulties were almost fully resolved. Further studies developing the standard procedure of the CSFTT should be considered.

키워드

참고문헌

  1. Adams RD, Fisher CM, Hakim S, Ojemann RG, Sweet WH : Symptomatic occult hydrocephalus with "normal" cerebrospinal-fluid pressure.a treatable syndrome. N Engl J Med 273 : 117-126, 1965 https://doi.org/10.1056/NEJM196507152730301
  2. Choi SH, Na DL, Lee BH, Hahm DS, Jeong JH, Yoon SJ, et al. : Estimating the validity of the Korean Version of Expanded Clinical Dementia Rating (CDR) Scale. J Korean Neurol Assoc 19 : 585-591, 2001
  3. Damasceno BP, Carelli EF, Honorato DC, Facure JJ : The predictive value of cerebrospinal fluid tap-test in normal pressure hydrocephalus. Arq Neuropsiquiatr 55 : 179-185, 1997 https://doi.org/10.1590/S0004-282X1997000200003
  4. Evans WA : An encephalographic ratio for estimating ventricular enlargement and cerebral atrophy. Arch Neurol Psychiatry 47 : 931-937, 1942 https://doi.org/10.1001/archneurpsyc.1942.02290060069004
  5. Ishikawa M, Hashimoto M, Kuwana N, Mori E, Miyake H, Wachi A, et al. : Guidelines for management of idiopathic normal pressure hydrocephalus. Neurol Med Chir (Tokyo) 48 Suppl : S1-S23, 2008 https://doi.org/10.2176/nmc.48.S1
  6. Ishikawa M, Hashimoto M, Mori E, Kuwana N, Kazui H : The value of the cerebrospinal fluid tap test for predicting shunt effectiveness in idiopathic normal pressure hydrocephalus. Fluids Barriers CNS 9 : 1, 2012 https://doi.org/10.1186/2045-8118-9-1
  7. Kahlon B, Sundbarg G, Rehncrona S : Comparison between the lumbar infusion and CSF tap tests to predict outcome after shunt surgery in suspected normal pressure hydrocephalus. J Neurol Neurosurg Psychiatry 73 : 721-726, 2002 https://doi.org/10.1136/jnnp.73.6.721
  8. Kang Y, Na DL, Hahn S : A validity study on the Korean Mini-Mental State Examination (K-MMSE) in dementia patients. J Korean Neurol Assoc 15 : 300-308, 1997
  9. Kubo Y, Kazui H, Yoshida T, Kito Y, Kimura N, Tokunaga H, et al. : Validation of grading scale for evaluating symptoms of idiopathic normal-pressure hydrocephalus. Dement Geriatr Cogn Disord 25 : 37-45, 2008 https://doi.org/10.1159/000111149
  10. Lee WC, Seo DH, Choe IS, Park SC, Ha YS, Lee KC : A comparative result of ventriculoperitoneal shunt, focusing mainly on gravity-assisted valve and programmable valve. J Korean Neurosurg Soc 48 : 251-258, 2010 https://doi.org/10.3340/jkns.2010.48.3.251
  11. Lee WJ, Wang SJ, Hsu LC, Lirng JF, Wu CH, Fuh JL : Brain MRI as a predictor of CSF tap test response in patients with idiopathic normal pressure hydrocephalus. J Neurol 257 : 1675-1681, 2010 https://doi.org/10.1007/s00415-010-5602-8
  12. Lim TS, Yong SW, Moon SY : Repetitive lumbar punctures as treatment for normal pressure hydrocephalus. Eur Neurol 62 : 293-297, 2009 https://doi.org/10.1159/000235808
  13. Malm J, Kristensen B, Karlsson T, Fagerlund M, Elfverson J, Ekstedt J : The predictive value of cerebrospinal fluid dynamic tests in patients with th idiopathic adult hydrocephalus syndrome. Arch Neurol 52 : 783-789, 1995 https://doi.org/10.1001/archneur.1995.00540320059013
  14. Marmarou A, Bergsneider M, Klinge P, Relkin N, Black PM : The value of supplemental prognostic tests for the preoperative assessment of idiopathic normal-pressure hydrocephalus. Neurosurgery 57 (3 Suppl) : S17-S28; discussion ii-v, 2005 https://doi.org/10.1227/01.NEU.0000144844.72403.7B
  15. Podsiadlo D, Richardson S : The timed "Up & Go" : a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39 : 142-148, 1991
  16. Ravdin LD, Katzen HL, Jackson AE, Tsakanikas D, Assuras S, Relkin NR : Features of gait most responsive to tap test in normal pressure hydrocephalus. Clin Neurol Neurosurg 110 : 455-461, 2008 https://doi.org/10.1016/j.clineuro.2008.02.003
  17. Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM : Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery 57 (3 Suppl) : S4-S16; discussion ii-v, 2005
  18. Sand T, Bovim G, Grimse R, Myhr G, Helde G, Cappelen J : Idiopathic normal pressure hydrocephalus : the CSF tap-test may predict the clinical response to shunting. Acta Neurol Scand 89 : 311-316, 1994
  19. Steffen TM, Hacker TA, Mollinger L : Age- and gender-related test performance in community-dwelling elderly people : Six-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and gait speeds. Phys Ther 82 : 128-137, 2002 https://doi.org/10.1093/ptj/82.2.128
  20. Udvarhelyi GB, Wood JH, James AE Jr, Bartelt D : Results and complications in 55 shunted patients with normal pressure hydrocephalus. Surg Neurol 3 : 271-275, 1975
  21. Virhammar J, Cesarini KG, Laurell K : The CSF tap test in normal pressure hydrocephalus : evaluation time, reliability and the influence of pain. Eur J Neurol 19 : 271-276, 2012 https://doi.org/10.1111/j.1468-1331.2011.03486.x
  22. Walchenbach R, Geiger E, Thomeer RT, Vanneste JA : The value of temporary external lumbar CSF drainage in predicting the outcome of shunting on normal pressure hydrocephalus. J Neurol Neurosurg Psychiatry 72 : 503-506, 2002
  23. Wikkelso C, Andersson H, Blomstrand C, Lindqvist G : The clinical effect of lumbar puncture in normal pressure hydrocephalus. J Neurol Neurosurg Psychiatry 45 : 64-69, 1982 https://doi.org/10.1136/jnnp.45.1.64

피인용 문헌

  1. Asymmetric and Upper Body Parkinsonism in Patients with Idiopathic Normal-Pressure Hydrocephalus vol.12, pp.4, 2013, https://doi.org/10.3988/jcn.2016.12.4.452
  2. Progressive histomorphometric analysis of the lateral ventricle and cerebral cortex of Wistar rats following kaolin-induced hydrocephalus vol.17, pp.1, 2013, https://doi.org/10.4103/njhs.njhs_9_17
  3. CSF Dynamics for Shunt Prognostication and Revision in Normal Pressure Hydrocephalus vol.10, pp.8, 2021, https://doi.org/10.3390/jcm10081711