• 한국식품위생안전성학회지
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• 제11권4호
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• pp.227-234
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• 1996

This study was designed to characterize endotoxin-induced prostaglandin production in primary cultured rat vascular smooth muscle cells (VSMC). The time course for prostaglandin synthesis in lipopolysaccharide (LPS)-stimulated VSMC showed that the maximum production was reached in 12 hours. LPS induced prostaglandin H2 synthase (PGHS) activity in VSMC and the time course profile in the changes of PGHS activity paralleled that of total prostaglandin production. Differential treatment showed that 4 hours' exposure to LPS was enough for the maximum effect on the prostaglandin production and this effect was completely inhibited by the co-treatment of actinomycin D, a transcription inhibitor. These results suggest that LPS effect might be determined within 4 hours. Actinomycin D increased PGHS activity without affecting prostaglandin production if added 4 hours after LPS treatment. On the other hand, cyclogeximide, a translation inhibitor, augmented LPS-induced prostaglandin production if treated during first four hours, but it inhibited LPS-induced PGHS activity regardless of treatment schedule. These results suggest the existence of multiple regulating mechanisms in the LPS-induced prostaglandin synthesis.

• 한국인쇄학회지
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• 제29권3호
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• pp.65-76
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• 2011

This research attempts to analyze communication effect of book-trailer as the promotion tool for book from various genre. For this research, existing book-trailers were classified into five types and prospective readers were selected as respondents for this research. Letter explanation type, Interview, cinematic production, stills and straplines, and animation were major type of book-trailer. Findings are 1) communication effect are different according to the type of book-trailers; 2) cinematic production and animation are the most effective type of book-trailers; 3) for memory and confirmation(sharing), a)stills and straplines, interview type, b) cinematic production and animation are founded as similar groups creating communication effect. Result of this research proposed the direction of production and practical use of book-trailer by scientific basis for publication marketer and book-trailer producer. ANOVA was used for analysis of hypothesis; measuring communication effect according to the type of book-trailer and sexuality.

• 기술혁신학회지
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• 제5권2호
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• pp.245-256
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• 2002

Measurement standards, as being widely recognized, is necessary for national economic development and advanced industrialization. Also measurement standards give reliability and fair trade to the producers and consumers. Macro-effect of measurement standards using estimation of cost function has four effects: 1) value-added causing effect, 2) effect of employment, 3) reduction effect transaction cost, 4) reduction effect defect rates. In this study, to investigate the impacts between specific and the other industries, we used I-O Table of Korea Bank. The relation between the value-added produced by original production factors and final use is determined through production level, and the relation can be investigated with production causing coefficient matrix. In this study, it was showed that the measurement standards investments including measurement only man power of industries were increased from 1995 rapidly. The establishment and maintenance of measurement standards contributes to reduce the defect rate of products in production process and improve the confidence of the product quality. The results from this study show that measurement technology contributes to improve quality, decrease defect rate, improve production process, develope new products, reduce prime cost and increase the consumer's confidence on the firms. Since these results indicate that measurement standards are very important in the point of their vast contribution, we hope our findings can contribute to encourage measurement activities in industries.

• 미생물학회지
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• 제25권4호
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• pp.360-366
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• 1987

For the production of pullulan from the high concentration of sugar, the utilization of sugars by a pullulan-producing fungus, Aureobasidium pullulans was examined. A. pullulans showed the different utilization patterns for sugars such as sucrose, maltose, and maltotriose. Especially for maltotriose, the hydrolysis of sugar was accompanied by a transferase activity. Glucose and maltose showed the inhibitory effect on the cell growth and the pullulan production at the sugar concentration higher than 0.28M, but sucrose showed the inhibitory effect at the sugar concentration higher than 0.14M. Among the sugars examined, sucrose gave the best result for the pullulan production. 27.5g/l of pullulan was obtained from 5% sucrose.

• 한국유기농업학회지
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• 제27권4호
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• pp.391-408
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• 2019

The purpose of this study is to analyze the spillover effect of R & D investment focusing on agriculture sector. Therefore, the Korean industry is divided into 18 industries and the data period including 1970 ~ 2014 is analyzed. In addition, the method is based on the analysis of the production function, the growth contribution of the production factor, and the spillover effect of other industries that affect the agricultural output. The results of this study are summarized as follows. First, R & D investment has a positive effect on the production of Korean agriculture. Second, the impact of high tech industry R & D investment on Korean agriculture is positive. Third, the R & D investment in the public sector is relatively higher than the R & D investment in the private sector. In the R & D stage, the R & D investment of the first level technology has a great influence on the production of agriculture. As a result of this study, governments should consider the above mentioned research results to determine resource priorities based on limited resources in relation to R & D investments that contribute to production and economic growth.

• Journal of Plant Biology
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• 제35권4호
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• pp.409-414
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• 1992

Quercetin(3,5,7,3'-4'-OH-flavone)이 보리(Hordeum vulgare var. hexastichon ASCHERS.) 자엽초 조직에서 옥신유발 에틸렌 생성을 현저히 촉진시켰다. $3{\times}10^{-5}\;M$의 quercetin에서 배양한 보리 자엽초 조직에서 옥신 유발 에틸렌 생성은 4시간 이후부터 증가되기 시작하여 8시간 이후에는 200%까지 증가되었다. Quercetin은 내재옥신인 indol-3-acetic acid(IAA)에 의한 에틸렌 생성은 촉진하나 합성 옥신인 2,4-dichlorophenoxyacetic acid(2,4-D)나 naphthaleneacetic acid(NAA)에 의한 에틸렌 생성에는 아무런 영향을 주지 않았다. 또한, 에틸렌 전구체인 1-aminocyclopropen-1-carboxylic acid(ACC) 유발 에틸렌 생성에도 촉진효과가 없었다. 이러한 결과는 에틸렌 생성에 대한 quercetin의 효과는 ACC 전단계에 작용한다는 것을 의미한다. Quercetin이 IAA 대사에 어떠한 영향을 미치는지 확인한 결과 조직을 quercetin에 1시간 배양시켰을 때 조직내 IAA oxidase 효소 활성이 90% 감소되었으며, IAA conjugation에는 별 영향을 미치지 않았다. 따라서, 옥신 유발 에틸렌 생성에 대한 quercetin의 촉진작용은 quercetin이 IAA oxidase의 활성을 억제시켜 높아진 IAA 수준이 옥신 유발 에틸렌 생성을 증가시키는 것으로 생각된다.

• Journal of Plant Biology
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• 제38권3호
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• pp.235-242
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• 1995

Effects of methyl jasmonate (MeJA) on ethylene production in tomato(Lycopersicon esculentum Mill.) hypocotyl segments and fruits were studied. Ethylene production in tomato hypocotyl segments was inhibited by the increasing concentratons of MeJA, and 450 $\mu$M of MeJA showed 50% inhibitory effect. Time course data indicate that this inhibitory effect of MeJA appeared after 3 h of incubation period and continued until 24 h. Inhibition of ethylene producton by MeJA was due to the decrease in 1-aminocyclopropane-1-carboxylic acid(ACC) synthase activity. However, MeJA treatment had no effect on ACC oxidase activity and the accumulaton of ACC oxidase mRNAs. MeJA also inhibited auxin-induced ethylene production by decreasing in ACC synthase activity. In contrast, MeJA stimulated ethylene production in tomato fruits. When 30 $\mu$L/mL MeJA was treated in a gaseous state, ethylene production doubled and this stimulating effect continued until 4 days. To investigate the mechanisms of MeJA on ethylene production, ACC synthase and ACC oxidase activities were examined after MeJA treatment. MeJA increased the activities of both ACC synthase and ACC oxidase, and induced ACC oxidase mRNA accumulation. These data suggest that MeJA plays distinct roles in the ethylene production in different tomato tissues. It is possible that MeJA affects differently the mechanisms of signal transuction leading to the ethylene biosynthesis.

• Asian-Australasian Journal of Animal Sciences
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• 제17권5호
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• pp.684-687
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• 2004

A study was conducted to determine the effect of live weight of pheasants on egg production and egg quality characteristics. A total of 48 ring-necked pheasants were divided into control, heavy, middle and light BW groups. Live weights of the control were 1,187 g, 1,352.92 g for heavy group, 1,247.92 g for middle group and 1,003.33 g for light group. Egg production of groups were found as 47.32, 42.82, 45.79 and 46.51% respectively, in 10 weeks of period. There were no statistical differences on egg production among the groups. The effect of live weight on egg weight, shape index, specific gravity, shell weight, shell thickness, Haugh Unit, yolk weight and albumen weight were found statistically significant (p<0.05). The effect of live weight on albumen index, membrane weight and membrane thickness were found not important (p>0.05). On the other hand, other important factors to be effective on the egg quality of pheasants should be investigated. As a result of this study, live weight of pheasant hens is not an important factor to obtain high egg production in pheasants. But, body conformation of breeding materials should be in good conditions.

• 약학회지
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• 제52권6호
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• pp.441-445
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• 2008

To investigate effect of caffeic acid on the intracellular reactive oxygen species production, we used DHE for intracellular superoxide anion production, DCF for intracellular ${H_2}{O_2}$ production and DHR for intracellular hydroperoxide production in Raw 264.7 cells. DPPH assay showed that antioxidant activity of caffeic acid with 39.5 ${\mu}M$ of ${IC}_{50}$ values was similar to that of ascorbic acid with 41.3 ${\mu}M$ of ${IC}_{50}$ values. Caffeic acid dose-dependently inhibited silica-induced ${H_2}{O_2}$ and hydroperoxide production but did not affect superoxide anion production in Raw 264.7 cells, which suggest that antioxidant effect of caffeic acid acts on the post-step of superoxide anion. On the other hand, caffeic acid showed a potent antioxidant effect in $lCuSO_4$-induced lipid peroxidation. Furthermore, plasma superoxide dismutase activity (3.43${\pm}$0.23 U/ml) in 10 mg/kg caffeic acid-fed mice was significantly higher than that (2.32${\pm}$0.24 U/ml) of control. From the above results, it is referred that caffeic acid appears to have potent anti-oxidant activity in both cell system and in vivo system.

• 디지털융복합연구
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• 제14권6호
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• pp.85-91
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• 2016

최근의 여러 연구는 럭셔리 브랜드가 자선과 결부될 때 긍정적으로 나타나는 소비자 반응의 기저에 죄책감 감소가 있음을 밝혔다. 본 연구는 더 나아가 럭셔리 브랜드가 부정적인 경영활동을 통해 이윤을 취함을 소비자가 알때, 럭셔리 브랜드가 자선활동을 하거나 하지 않음에 따라 죄책감 감소의 영향이 달라지며, 이로 인해 소비자의 구매의도도 상이하게 나타남을 보이고자 하였다. 2(자선활동 연계 여부) x 2(생산방식 지각: 부정 vs. 통제) 피험자 간 설계로 진행된 실험 결과, 럭셔리 브랜드의 자선 연계는 제품 구매의도에 긍정적으로 영향을 미쳤으며, 제품 생산방식이 부정적이라고 지각한 경우 그렇지 않을 때보다 구매의도가 낮았다. 그런데 자선 연계가 구매의도에 미치는 영향은 제품 생산방식의 지각에 의해 조절되었는데, 자선 연계가 되어있을 때의 지각의 차이가 미치는 영향이 자선 연계가 없을 때의 지각의 차이가 미치는 영향보다 큰 것으로 나타났다. 한편 자선 연계 여부가 구매의도에 미치는 영향 및 자선 연계 여부와 생산방식 지각의 상호작용이 구매의도에 미치는 영향 모두 죄책감 감소에 의해 매개되는 것으로 나타났다. 본 연구는 럭셔리 브랜드 제품의 자선연계에 있어 소비자가 제품 생산 방식의 윤리성을 어떻게 지각하는 지가 중요한 요인이 될 수 있음을 밝혔다는 데 학문적 및 실무적으로 기여하고 있다.