• 한국가금학회지
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• 제34권1호
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• pp.77-83
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• 2007

Poultry products including meat and eggs constitute a major protein source in the American diet and disease-causing pathogens represent major challenges to the poultry industry. More than 95% of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper-virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2005년도 국제심포지움
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• pp.19-27
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• 2005

• 한국가금학회지
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• 제26권3호
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• pp.149-170
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• 1999

Protozoa of the genus Eimeria are the etiologic agents of avian coccidiosis, the most economically important Parasitic disease for the poultry industry. Coccidia multiply in intestinal epithelial cells of a wide range of hosts, including livestock in addition to poultry. Chemotherapy is extensively used to control coccidiosis. However, development of drug resistance by Eimeria parasites, the intensive cost and labor involved in the identification of new anticoccidial compounds and public awareness of drug residues in foods warrant alternative methods to prevent coccidiocic in the fast growing poultry industry. For these reasons, there is a great interest in developing vaccines against avian coccidiosis. Live Eimeria vaccines confer protective immunity, however a significant disadvantage of using these types of vaccines is their pathogenicity. Live parasites with attenuated pathogenicity also usually produce immunity but may revert back to a pathogenic form and may be contaminated with other pathogenic organisms. Killed Eimeria vaccines are safer but, unlike live attenuated vaccines, are not able to generate cytotoxic T lymphocyte responses. Recombinant vaccines are biochemically purified proteins produced by genetic engineering that consist of particular epitopes or metabolites of Eimeria. Unlike live attenuated organisms, recombinant vaccines do not possess as much risk and generally are able to induce both humoral and cell mediated immunity. DNA vaccines consist of genes encoding immunogenic proteins of pathogens that are directly administered into the host in a manner that the gene is expressed and the resulting protein generates a protective immune response. Although all of these different types of vaccines have been applied to coccidiosis, this disease continues to cause substantial morbidity and mortality in the poultry industry. Future development of an effective vaccine against coccidiosis will depend on further investigation of protective immunity to Eimeria infection and identification of important immundgenic parasite molecules.

• 한국가금학회지
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• 제5권1호
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• pp.18-22
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• 1978

수요급증에 대비한 과감한 기전구축, 축산자급 기반구축을 위한 자금의 확대지원, 축산물의 안정적 공급을 위한 안정가격제 확립, 축산물과 사료의 수급원활과 유통혁신, 산지개발의 촉진과 축산단지 및 전기업 목장의 확대조성, 축산의 원활한 진흥을 위한 제도적 미비점 보완. (중략)

• 한국가금학회지
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• 제5권1호
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• pp.7-14
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• 1978

미국의 양계산업은 한마디로 해서 산의 정상에 도달한 감이 있다. 즉 근년에 와서는 호당 사양규모는 증가하고 있으나 사양수수는 2억 7천만수를 전후하여 년도에 따라서 큰 변동이 없다. 계란소비량은 10년전만 해도 1인당 년간 350개정도 소비하였으나 차차로 감소하여 근년에 와서는 1인당 소비량이 270개로 감소하고 있는 현상을 볼 수 있다. (중략)

• 한국가금학회지
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• 제6권2호
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• pp.109-109
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• 1979

양계 업자와 사료업자는 가금의 질병, 영양, 유전이 끊임없이 변화하는 복잡한 환경에서 적절한 경영방법을 결정하지 않으면 안된다. (중략)

• 한국가금학회지
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• 제5권1호
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• pp.23-45
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• 1978

금번 미사료곡물협회 한국지부의 주선과 정부의 파견추천에 의하여 선진 양계국인 미국의 양계관련 산업분야를 시찰하게 되었으며 이를 계기로 하여 브라질, 리오데자네이로에서 개최되는 제16차 세계 가금학회 총회까지 참석하게 되었다. 1978년 9월 2일부터 동년 9월 27일까지 25일간 학계와 관련업계가 같은 Team으로 (12명) 참여하게 된 것은 퍽 뜻이 있었던 것으로 생각된다. (중략)

• Asian-Australasian Journal of Animal Sciences
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• 제18권1호
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• pp.113-132
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• 2005

With the demand for free-range products increasing and the pressure on the intensive poultry industry to improve poultry welfare especially in western countries, the number of free-range poultry farms has increased significantly. The USA, Australia and European countries have developed Codes of Practice for free-range poultry farming which detail the minimum standards of husbandry and welfare for birds. However, the performance and liveability of free-range birds needs to be improved and more knowledge is required on bird husbandry, feed supply, disease control and heat wave management. This review examines the husbandry, welfare, nutrition and disease issues associated with free-range poultry systems and discusses the potential of incorporating free-range poultry into a crop-pasture rotation system.

• 한국가금학회지
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• 제39권1호
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• pp.53-62
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• 2012

In the past, poultry nutrition has focussed on increasing the production efficiency to meet the progress achieved in the genetic potential of broilers and layers. Future directions in poultry nutrition will be driven by not only by the need to maximise biological and economic performance of birds, but also by societal issues (environment, antibiotic growth promoters, welfare, traceability and use of genetically modified ingredients). Key advances in poultry nutrition are discussed and future directions, which can be expected, are highlighted. Given the tightening supply and ever-increasing cost of raw materials, there will be more pressure to extract every unit of energy and nutrients from feed ingredients. In this context, a number of feed additives are expected to play an increasingly significant role. Feed enzymes and crystalline amino acids, in particular, will have a profound effect on future sustainability of the poultry industry. Future nutritional research need to focus on identifying the barriers to effective digestion and utilisation of nutrients and, to achieve this objective, nutritionists must combine their expertise with those of specialising in other biological sciences, including immunology, microbiology, histology and molecular biology.

• 한국가금학회지
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• 제20권3호
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• pp.161-170
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• 1993

Prospects are briefly reviewed for further advances in current poultry industry technology in the foreseeable future. It is concluded that in the most advanced industries progress should continue at a similar rate to the recent past in conventional genetics and breeding, nutrition and disease control. Significant benefits will also follow in the short-term from the application of molecular biotechnology to disease diagnosis and vaccine production. Technical advances now make it possible to produce transgenic chickens at acceptable success rates but applications of this technology to poultry breeding will not become significant till we have sufficient knowledge of the poultry genome, and especially the genes involved in production performance. For the undeveloped and less advanced industries it is argued that the level of advanced technologies to be implemented in those countries should be decided largely on market forces, informed by objective assessment of the diverse options available. The need for urgent international action on conservation of poultry genetic resources is also stressed.